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Gene: ISX (intestine specific homeobox) Homo sapiens
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Symbol: ISX
Name: intestine specific homeobox
Description: Exhibits sequence-specific double-stranded DNA binding activity. Predicted to be involved in enteric nervous system development; negative regulation of intestinal absorption; and regulation of vitamin A metabolic process. Predicted to localize to nuclear chromatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp781N2395; intestine-specific homeobox; MGC138417; pancreas-intestine homeodomain transcription factor; Pix-1; RAX-like homeobox; RAXLX
Orthologs:
Mus musculus (house mouse) : Isx (intestine specific homeobox)  MGI  Alliance
Rattus norvegicus (Norway rat) : Isx (intestine-specific homeobox)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Isx (intestine specific homeobox)
Pan paniscus (bonobo/pygmy chimpanzee) : ISX (intestine specific homeobox)
Canis lupus familiaris (dog) : ISX (intestine specific homeobox)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Isx (intestine specific homeobox)
Sus scrofa (pig) : ISX (intestine specific homeobox)
Chlorocebus sabaeus (African green monkey) : ISX (intestine specific homeobox)
Heterocephalus glaber (naked mole-rat) : Isx (intestine specific homeobox)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2235,066,136 - 35,087,387 (+)EnsemblGRCh38hg38GRCh38
GRCh382235,066,158 - 35,087,387 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372235,462,130 - 35,483,380 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,792,130 - 33,813,380 (+)NCBINCBI36hg18NCBI36
Celera2219,264,831 - 19,286,082 (+)NCBI
Cytogenetic Map22q12.3NCBI
HuRef2218,424,658 - 18,445,908 (+)NCBIHuRef
CHM1_12235,420,992 - 35,442,242 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ISX
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605896
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.