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Gene: AMOT (angiomotin) Homo sapiens
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Symbol: AMOT
Name: angiomotin
Description: Exhibits angiostatin binding activity and signaling receptor activity. Involved in several processes, including hippo signaling; negative regulation of vascular permeability; and positive regulation of blood vessel endothelial cell migration. Localizes to several cellular components, including the actin cytoskeleton; bicellular tight junction; and ruffle. Colocalizes with the COP9 signalosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: angiomotin p130 isoform; angiomotin p80 isoform; KIAA1071
Orthologs:
Mus musculus (house mouse) : Amot (angiomotin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Amot (angiomotin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Amot (angiomotin)
Pan paniscus (bonobo/pygmy chimpanzee) : AMOT (angiomotin)
Canis lupus familiaris (dog) : AMOT (angiomotin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Amot (angiomotin)
Sus scrofa (pig) : AMOT (angiomotin)
Chlorocebus sabaeus (African green monkey) : AMOT (angiomotin)
Heterocephalus glaber (naked mole-rat) : Amot (angiomotin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX112,774,503 - 112,840,815 (-)Ensembl
GRCh38X112,774,503 - 112,840,946 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X112,018,105 - 112,084,136 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X111,904,761 - 111,970,699 (-)NCBINCBI36hg18NCBI36
Build 34X111,823,875 - 111,890,188NCBI
CeleraX112,502,736 - 112,568,672 (-)NCBI
Cytogenetic MapXq23NCBI
HuRefX101,645,090 - 101,710,229 (-)NCBIHuRef
CHM1_1X111,929,234 - 111,995,169 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on AMOT
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1344662
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.