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Gene: ANGPTL8 (angiopoietin like 8) Homo sapiens
Symbol: ANGPTL8
Name: angiopoietin like 8
Description: ENCODES a protein that exhibits hormone activity (inferred); INVOLVED IN positive regulation of protein processing; regulation of lipid metabolic process; regulation of lipoprotein metabolic process; FOUND IN extracellular region; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; benzo[a]pyrene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: angiopoietin-like 8; angiopoietin-like protein 8; betatrophin; betatrophin variant 1; betatrophin variant 2; C19orf80; hepatocellular carcinoma-associated gene TD26; hepatocellular carcinoma-associated protein TD26; lipasin; PRO1185; PVPA599; RIFL; TD26
Mus musculus (house mouse) : Angptl8 (angiopoietin-like 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Angptl8 (angiopoietin-like 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Angptl8 (angiopoietin like 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ANGPTL8 (angiopoietin like 8)
Canis lupus familiaris (dog) : ANGPTL8 (angiopoietin like 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Angptl8 (angiopoietin like 8)
Sus scrofa (pig) : ANGPTL8 (angiopoietin like 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381911,239,619 - 11,241,943 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371911,350,295 - 11,352,619 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361911,209,817 - 11,213,619 (+)NCBINCBI36hg18NCBI36
Celera1911,245,140 - 11,247,464 (+)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1910,926,369 - 10,928,693 (+)NCBIHuRef
CHM1_11911,351,357 - 11,353,681 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ANGPTL8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1607022
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-10-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.