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Gene: CYP51A1 (cytochrome P450 family 51 subfamily A member 1) Homo sapiens
Symbol: CYP51A1
Name: cytochrome P450 family 51 subfamily A member 1
Description: Exhibits heme binding activity and sterol 14-demethylase activity. Involved in steroid biosynthetic process. Localizes to the endoplasmic reticulum.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CP51; CYP51; CYPL1; CYPLI; cytochrome P450 51A1; cytochrome P450, 51 (lanosterol 14-alpha-demethylase); cytochrome P450, family 51, subfamily A, polypeptide 1; cytochrome P450-14DM; cytochrome P45014DM; cytochrome P450LI; lanosterol 14-alpha demethylase; lanosterol 14-alpha-demethylase; LDM; P450-14DM; P450L1; sterol 14-alpha demethylase
Mus musculus (house mouse) : Cyp51 (cytochrome P450, family 51)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cyp51 (cytochrome P450, family 51)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102027002 (lanosterol 14-alpha demethylase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100985833 (lanosterol 14-alpha demethylase)
Canis lupus familiaris (dog) : CYP51A1 (cytochrome P450 family 51 subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101955024 (lanosterol 14-alpha demethylase)
Sus scrofa (pig) : CYP51 (cytochrome P450, family 51, subfamily A, polypeptide 1)
more info ...
Related Pseudogenes: CYP51A1P1   CYP51A1P2   CYP51A1P3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38792,112,149 - 92,134,745 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37791,741,463 - 91,764,059 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36791,579,402 - 91,601,946 (-)NCBINCBI36hg18NCBI36
Build 34791,386,116 - 91,408,661NCBI
Celera786,446,011 - 86,468,618 (-)NCBI
Cytogenetic Map7q21.2NCBI
HuRef786,348,902 - 86,371,499 (-)NCBIHuRef
CHM1_1791,671,533 - 91,694,128 (-)NCBICHM1_1
CRA_TCAGchr7v2791,070,701 - 91,093,297 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CYP51A1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345262
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.