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Gene: CYP51A1 (cytochrome P450 family 51 subfamily A member 1) Homo sapiens
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Symbol: CYP51A1
Name: cytochrome P450 family 51 subfamily A member 1
Description: Exhibits heme binding activity and sterol 14-demethylase activity. Involved in steroid biosynthetic process. Localizes to the endoplasmic reticulum.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CP51; CYP51; CYPL1; CYPLI; cytochrome P450 51A1; cytochrome P450, 51 (lanosterol 14-alpha-demethylase); cytochrome P450, family 51, subfamily A, polypeptide 1; cytochrome P450-14DM; cytochrome P45014DM; cytochrome P450LI; lanosterol 14-alpha demethylase; lanosterol 14-alpha-demethylase; LDM; P450-14DM; P450L1; sterol 14-alpha demethylase
Orthologs:
Mus musculus (house mouse) : Cyp51 (cytochrome P450, family 51)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cyp51 (cytochrome P450, family 51)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102027002 (lanosterol 14-alpha demethylase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100985833 (lanosterol 14-alpha demethylase)
Canis lupus familiaris (dog) : CYP51A1 (cytochrome P450 family 51 subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101955024 (lanosterol 14-alpha demethylase)
Sus scrofa (pig) : CYP51 (cytochrome P450, family 51, subfamily A, polypeptide 1)
more info ...
Related Pseudogenes: CYP51A1P1   CYP51A1P2   CYP51A1P3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38792,112,149 - 92,134,745 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37791,741,463 - 91,764,059 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36791,579,402 - 91,601,946 (-)NCBINCBI36hg18NCBI36
Build 34791,386,116 - 91,408,661NCBI
Celera786,446,011 - 86,468,618 (-)NCBI
Cytogenetic Map7q21.2NCBI
HuRef786,348,902 - 86,371,499 (-)NCBIHuRef
CHM1_1791,671,533 - 91,694,128 (-)NCBICHM1_1
CRA_TCAGchr7v2791,070,701 - 91,093,297 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CYP51A1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345262
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.