CYP51A1 (cytochrome P450 family 51 subfamily A member 1)

Gene: CYP51A1 (cytochrome P450 family 51 subfamily A member 1) Chlorocebus sabaeus

Analyze

Symbol:

CYP51A1

Name:

cytochrome P450 family 51 subfamily A member 1

RGD ID:

18759176

Description:

ENCODES a protein that exhibits sterol 14-demethylase activity (ortholog); INVOLVED IN cholesterol biosynthetic process via 24,25-dihydrolanosterol (ortholog); negative regulation of amyloid-beta clearance (ortholog); negative regulation of protein catabolic process (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH Antley-Bixler syndrome (ortholog); cataract (ortholog); cerebral cavernous malformation (ortholog); FOUND IN acrosomal vesicle (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

lanosterol 14-alpha demethylase

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	56,865,498 - 56,888,196 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	56,865,312 - 56,886,698 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	47,377,473 - 47,400,184 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Antley-Bixler syndrome (ISO)

cataract (ISO)

cerebral cavernous malformation (ISO)

diabetes mellitus (ISO)

genetic disease (ISO)

Hypercholesterolemia (ISO)

long QT syndrome (ISO)

pleomorphic xanthoastrocytoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bile acid biosynthetic process (IEA)

cholesterol biosynthetic process via 24,25-dihydrolanosterol (ISO)

cholesterol homeostasis (IEA)

cholesterol metabolic process (IEA)

negative regulation of amyloid-beta clearance (ISO)

negative regulation of protein catabolic process (ISO)

negative regulation of protein secretion (ISO)

organic hydroxy compound biosynthetic process (IEA)

positive regulation of oocyte development (ISO)

response to human chorionic gonadotropin (ISO)

response to insulin (ISO)

response to lead ion (ISO)

small molecule biosynthetic process (IEA)

spermatogenesis (ISO)

steroid biosynthetic process (IEA)

sterol metabolic process (IEA)

Cellular Component

acrosomal vesicle (ISO)

endoplasmic reticulum membrane (IEA)

intracellular membrane-bounded organelle (IEA)

membrane (IEA)

Molecular Function

heme binding (IEA)

iron ion binding (IEA)

metal ion binding (IEA)

monooxygenase activity (IEA)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (IEA)

oxysterol 7-alpha-hydroxylase activity (IEA)

steroid 7-alpha-hydroxylase activity (IEA)

sterol 14-demethylase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

alendronate pharmacodynamics pathway (ISO)

cholesterol biosynthetic pathway (ISO)

cholesterol ester storage disease pathway (ISO)

congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway (ISO)

desmosterolosis pathway (ISO)

hypercholesterolemia pathway (ISO)

ibandronate pharmacodynamics pathway (ISO)

mevalonic aciduria pathway (ISO)

nitrogenous bisphosphonate pharmacodynamics pathway (ISO)

pamidronate pharmacodynamics pathway (ISO)

risedronate pharmacodynamics pathway (ISO)

Smith-Lemli-Opitz Syndrome pathway (ISO)

statin pharmacodynamics pathway (ISO)

Wolman disease pathway (ISO)

X-linked dominant chondrodysplasia punctata 2 pathway (ISO)

zoledronate pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

CYP51A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	56,865,498 - 56,888,196 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	56,865,312 - 56,886,698 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	47,377,473 - 47,400,184 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

CYP51A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	92,112,153 - 92,134,803 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	92,084,987 - 92,134,803 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	91,741,467 - 91,764,117 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	91,579,402 - 91,601,946 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	91,386,116 - 91,408,661	NCBI
Celera	7	86,446,011 - 86,468,618 (-)	NCBI		Celera
Cytogenetic Map	7	q21.2	NCBI
HuRef	7	86,348,902 - 86,371,499 (-)	NCBI		HuRef
CHM1_1	7	91,671,533 - 91,694,128 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	93,353,434 - 93,376,082 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	91,070,701 - 91,093,297 (-)	NCBI

Cyp51
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	4,130,674 - 4,154,697 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	4,131,145 - 4,154,746 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	4,080,674 - 4,104,697 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	4,081,145 - 4,104,746 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	4,080,674 - 4,104,697 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	4,086,680 - 4,110,703 (-)	NCBI		MGSCv36	mm8
Celera	5	4,010,747 - 4,034,762 (-)	NCBI		Celera
Cytogenetic Map	5	A1	NCBI
cM Map	5	2.3	NCBI

Cyp51
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	30,991,693 - 31,010,147 (+)	NCBI		GRCr8
mRatBN7.2	4	30,036,956 - 30,055,410 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	30,036,865 - 30,055,410 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	35,009,705 - 35,028,159 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	30,935,797 - 30,954,251 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	29,331,773 - 29,350,227 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	27,175,564 - 27,194,018 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	27,175,243 - 27,194,018 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	27,078,790 - 27,097,244 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	26,752,677 - 26,771,131 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	26,758,233 - 26,776,686 (+)	NCBI
Celera	4	25,462,810 - 25,481,264 (+)	NCBI		Celera
Cytogenetic Map	4	q13	NCBI

LOC102027002
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955432	9,092,933 - 9,112,615 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955432	9,092,923 - 9,112,615 (-)	NCBI	ChiLan1.0	ChiLan1.0

CYP51A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	109,998,616 - 110,022,815 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	158,262,334 - 158,287,365 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	84,110,130 - 84,132,870 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	97,708,806 - 97,730,486 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	97,708,806 - 97,729,824 (-)	Ensembl	panpan1.1		panPan2

CYP51A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	17,746,654 - 17,767,019 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	17,746,656 - 17,766,658 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	17,307,241 - 17,328,397 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	17,552,569 - 17,573,808 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	17,550,375 - 17,573,565 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	17,710,915 - 17,732,068 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	17,425,396 - 17,446,546 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	17,699,282 - 17,720,469 (-)	NCBI		UU_Cfam_GSD_1.0

LOC101955024
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	31,136,259 - 31,159,424 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936621	2,209,199 - 2,232,531 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936621	2,209,255 - 2,232,404 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CYP51A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	72,057,511 - 72,079,444 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	72,057,506 - 72,079,587 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	78,792,905 - 78,814,951 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC101724157
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624809	1,080,656 - 1,100,254 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624809	1,080,427 - 1,110,802 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium	36	1	60
Low		19
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007982191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007982192	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000010644 ⟹ ENSCSAP00000008733

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	21	56,865,312 - 56,886,698 (+)	Ensembl

RefSeq Acc Id:

XM_007982191 ⟹ XP_007980382

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	21	56,865,612 - 56,888,196 (+)	NCBI
Vero_WHO_p1.0	NW_023666042	47,377,473 - 47,400,068 (-)	NCBI

Sequence:

show sequence

GTGACGCACAAGGTGGCGCGCGTGGAACCCGAGGGGTGGGGCTGGGTTTAGTAGGAAACCTGGG
GGCCGGGGCCGCCTGTGGACGACCATCTGCCAGCTTCTCTCGCTCCGTCGACTAGGAGGAGCGG
TGGCGACCTCGGCCTTCAGTGTCTTCGGCAGAGTGAAATGGCGGCGGCGGCCGGGATGATGTTG
CTGGGCTTGCTGCAGGCGGGTGGGTCGGTGCTGGGCCAGGCGATGGAGAAGGTGACAGGCGGCA
ACCTCCTGTCCATGCTGCTGATCGCCTGCGCCTTCACCCTCAGCTTAGTCTACCTGTTCCGTCT
CGCCGCCGGCCACCTGGTCCAGCTGCCCGCAGGGGCGAAAAGTCCTCCATACATTTTCTCCCCG
ATTCCATTCCTTGGGCATGCCATAGCATTTGGGAAAAGTCCAGTTGAATTTCTAGAAAATGCAT
ATGAGAAGTATGGACCTGTATTTAGTTTTACCATGGTAGGCAAGACATTTACTTACCTTCTGGG
GAGTGATGCTGCTGCACTGCTTTTTAATAGTAAAAATGAAGACCTGAATGCAGAAGATGTCTAC
AGTCGCCTGACAACACCTGTGTTTGGGAAGGGAGTTGCATACGATGTGCCTAATCCAGTTTTCT
TGGAGCAGAAGAAAATGTTAAAAAGTGGCCTTAACATTGCCCACTTTAAACAGCATGTTTCTAT
AATTGAAAAAGAAACAAAGGAATACTTTCAGAGTTGGGGAGAAAGTGGAGAAAAAAATGTGTTT
GAAGCTCTTTCTGAGCTCATAATTTTAACAGCTAGCCATTGTTTGCATGGAAAGGAAATCAGAA
GTCAACTCAATGAAAAGGTGGCACAGCTGTATGCAGATTTGGATGGAGGTTTCAGCCATGCAGC
CTGGCTGTTACCAGGTTGGCTGCCTTTGCCTAGTTTCAGACGCAGGGACAGAGCTCATCGGGAA
ATCAAGAATATTTTCTATAAGGCAATCCAGAAACGCAGACAGTCTCAAGAAAAAATTGATGACA
TTCTGCAAACTTTACTAGATGCTACATACAAGGATGGGCGTCCTTTGACTGACGATGAAGTAGC
AGGGATGCTTATTGGACTACTCTTGGCAGGGCAGCATACATCCTCAACTACTAGTGCTTGGATG
GGCTTCTTTTTGGCCAGAGACAAAACACTTCAAGAAAAATGTTATTTAGAACAGAAAACAGTCT
GTGGAGAGAATCTGCCTCCTTTAACTTATGACCAGCTCAAGGATCTAAATTTACTTGATCGTTG
TATAAAAGAAACATTAAGACTTAGACCTCCTATAATGATCATGATGAGAATGGCCAGAACTCCT
CAGACTGTGGCAGGGTATACCATTCCTCCAGGACATCAGGTGTGTGTTTCTCCCACTGTCAATC
AAAGACTTAAAGACTCATGGGTAGAACGCCTGGACTTTAATCCTGATCGCTACTTACAGGATAA
CCCAGCATCAGGGGAAAAGTTTGCCTATGTGCCGTTTGGAGCTGGGCGTCATCGTTGTATTGGG
GAAAATTTTGCCTATGTTCAAATTAAGACAATTTGGTCCACTATGCTTCGTTTATATGAATTTG
ATCTCATTGATGGATACTTTCCCACCGTGAATTATACAACTATGATTCACACCCCTGAAAACCC
AGTTATTCGTTACAAACGAAGATCAAAATGAGAAGACTGCCAGGAACTAATATATGTGATCGTC
ACTGTAAGCCATAAAGGCGTTCGAAGAGAATGAAGTGTACAAAACAACTCTTGTAGTGTACTGT
TTTTTTGAGTGTGTAATTCTAAAAGCCAGTTTAACTTATGATTTAGTATTTTGTTAACTGAATG
GTTCTATCAAATATAAGAGCATTTGAAACATTTTCTAATAGTTATGATACTTATACATGTGCTT
TCAGGAAGTTCATTAGTAAAACAACTGTTCAGGGGGGGATCTAGGTAATTGGCAGATTCTAAAT
AATATAATTTCCATGTAGTAATTTTAAGAGCATAGCTCTTGCCAAGTAAGTTCAGGGTATTCAA
ACCTTGGACTAGTCCTGCAAGGTATAAAGAATAAAAATCCCAGTGAGATACTTGGAAACCACAG
GTTATTATTTATCTGGGCAATTATTGTGTGTGTGAGGACGGAAGAGGGAATAATCGAACATCTA
AAGCCTTGAATAAGAGAATACTAACTGTTTTAGTATGATGATATTCAGAAATGGAGATGTTATA
GAAAAATAAATCCTTTGGAATTTTAACTAAAATCACTGCATATAGGAAATTAAGAGATCTAGGA
CCATATTTTATAAGATTTCTTAAAAATAATGTAATTATTAATGCTAAAGACTGCTCGTGTATCT
TGATCTAATTACTAAATAATTACATATTTACCTGATAAGTATGTATCTAGTTCTACAAGGTCAC
ATTTATGTGGAAGTCCAAAGTCAAGTCCTTAGGGGATAATTTTGTTTTGGCTCACATGTTCCCT
GCTTCCTCTCTTTTTTTTTTTTTTGAGATGGAGTCTAGCTCTGTTGCCCAGGCTGGAGTGCAGT
GGCACGATCTCGGCTCATTGGATCCTCCGCCTCCCGGGTTCAAGCAAATCTCTGCCTCAGCCTC
CCAAGTAGTTGGGATTACAGGCGCCTACCACCATGCCTGGCTAATTTTTTGTATTTTTAGTAGA
GACGGAGGTTTCACTATGTTGGCCAGGCTAGTCTTGAACTCCTGACCTCGTGATCCACCTGCCT
CAGCCTCCCGAAGTGCTGGGGTTACAGGCATGAGCCACCGGGCCTGGCCTTCCCTGCTTCCTCT
CTAGAATCCAGTTAGGGATGTTTGTTACTACTTGTGTTAAAACAGTTAAACTAACTTTTTTCTT
TTAAAAATGTGAGATCAGTGAACTCTGACTTTAAGATAATCTGAAACAAGGTCCTTGGGAGTAA
TATAATTGGTCACATTCTGTAAAGCACGTTCTGTTTAGGAATCAACTGATCTTAAATTATAACT
CCGGGCCTAACTATATGAGATGGCTGAAAAAATACCACATCATCTGTTTTCACTAGATGATGCC
AAAATATTTTGCTTTATGTATATTACAGTTATTTTTAAAAGGCTGGAAGACTCATGTTAAACTC
TAATTGTGAAGGCAGAATCTCTGCTAATTTTTCACATTAAAATTCTCTTTGAAAAAA

hide sequence

RefSeq Acc Id:

XM_007982192 ⟹ XP_007980383

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	21	56,865,498 - 56,886,892 (+)	NCBI
Vero_WHO_p1.0	NW_023666042	47,378,865 - 47,400,184 (-)	NCBI

Sequence:

show sequence

ACTGTGCCACAGGCACAGCCCGCTTCCTCAGGTCCCCTATCCCGCGCAAGAAGACCACGGCTTC
GCAGAGTGTTATTTAAGAGGCGTGGCCAGCGGAACATCCCGCCCCATTCTGTGACGCACAAGAA
AAGTCCTCCATACATTTTCTCCCCGATTCCATTCCTTGGGCATGCCATAGCATTTGGGAAAAGT
CCAGTTGAATTTCTAGAAAATGCATATGAGAAGTATGGACCTGTATTTAGTTTTACCATGGTAG
GCAAGACATTTACTTACCTTCTGGGGAGTGATGCTGCTGCACTGCTTTTTAATAGTAAAAATGA
AGACCTGAATGCAGAAGATGTCTACAGTCGCCTGACAACACCTGTGTTTGGGAAGGGAGTTGCA
TACGATGTGCCTAATCCAGTTTTCTTGGAGCAGAAGAAAATGTTAAAAAGTGGCCTTAACATTG
CCCACTTTAAACAGCATGTTTCTATAATTGAAAAAGAAACAAAGGAATACTTTCAGAGTTGGGG
AGAAAGTGGAGAAAAAAATGTGTTTGAAGCTCTTTCTGAGCTCATAATTTTAACAGCTAGCCAT
TGTTTGCATGGAAAGGAAATCAGAAGTCAACTCAATGAAAAGGTGGCACAGCTGTATGCAGATT
TGGATGGAGGTTTCAGCCATGCAGCCTGGCTGTTACCAGGTTGGCTGCCTTTGCCTAGTTTCAG
ACGCAGGGACAGAGCTCATCGGGAAATCAAGAATATTTTCTATAAGGCAATCCAGAAACGCAGA
CAGTCTCAAGAAAAAATTGATGACATTCTGCAAACTTTACTAGATGCTACATACAAGGATGGGC
GTCCTTTGACTGACGATGAAGTAGCAGGGATGCTTATTGGACTACTCTTGGCAGGGCAGCATAC
ATCCTCAACTACTAGTGCTTGGATGGGCTTCTTTTTGGCCAGAGACAAAACACTTCAAGAAAAA
TGTTATTTAGAACAGAAAACAGTCTGTGGAGAGAATCTGCCTCCTTTAACTTATGACCAGCTCA
AGGATCTAAATTTACTTGATCGTTGTATAAAAGAAACATTAAGACTTAGACCTCCTATAATGAT
CATGATGAGAATGGCCAGAACTCCTCAGACTGTGGCAGGGTATACCATTCCTCCAGGACATCAG
GTGTGTGTTTCTCCCACTGTCAATCAAAGACTTAAAGACTCATGGGTAGAACGCCTGGACTTTA
ATCCTGATCGCTACTTACAGGATAACCCAGCATCAGGGGAAAAGTTTGCCTATGTGCCGTTTGG
AGCTGGGCGTCATCGTTGTATTGGGGAAAATTTTGCCTATGTTCAAATTAAGACAATTTGGTCC
ACTATGCTTCGTTTATATGAATTTGATCTCATTGATGGATACTTTCCCACCGTGAATTATACAA
CTATGATTCACACCCCTGAAAACCCAGTTATTCGTTACAAACGAAGATCAAAATGAGAAGACTG
CCAGGAACTAATATATGTGATCGTCACTGTAAGCCATAAAGGCGTTCGAAGAGAATGAAGTGTA
CAAAACAACTCTTGTAGTGTACTGTTTTTTTGAGTGTGTAATTCTAAAAGCCAGTTTAACTTAT
GATTTAGTATTTTGTTAACTGAATGGTTCTATCAAATATAAGAGCATTTGAAACATTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_007980382	(Get FASTA)	NCBI Sequence Viewer
	XP_007980383	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000008733
	ENSCSAP00000008733.1

RefSeq Acc Id:	XP_007980383 ⟸ XM_007982192
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_007980382 ⟸ XM_007982191
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RJE4 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000008733 ⟸ ENSCSAT00000010644

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000012548	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000010644.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.630.10	UniProtKB/TrEMBL
InterPro	Cyt_P450	UniProtKB/TrEMBL
	Cyt_P450_CS	UniProtKB/TrEMBL
	Cyt_P450_E_grp-IV	UniProtKB/TrEMBL
	Cyt_P450_sf	UniProtKB/TrEMBL
KEGG Report	csab:103226567	UniProtKB/TrEMBL
NCBI Gene	CYP51A1	ENTREZGENE
PANTHER	24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE	UniProtKB/TrEMBL
	CYTOCHROME P450 FAMILY 7	UniProtKB/TrEMBL
Pfam	p450	UniProtKB/TrEMBL
PRINTS	EP450IV	UniProtKB/TrEMBL
	P450	UniProtKB/TrEMBL
PROSITE	CYTOCHROME_P450	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48264	UniProtKB/TrEMBL
UniProt	A0A0D9RJE4	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:83416	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - SMPDB