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Gene: FRK (fyn related Src family tyrosine kinase) Homo sapiens
Symbol: FRK
Name: fyn related Src family tyrosine kinase
Description: Exhibits protein tyrosine kinase activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to cytosol and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: fyn-related kinase; fyn-related Src family tyrosine kinase; GTK; nuclear tyrosine protein kinase RAK; protein-tyrosine kinase 5; PTK5; PTK5 protein tyrosine kinase 5; RAK; tyrosine-protein kinase FRK
Mus musculus (house mouse) : Frk (fyn-related kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Frk (fyn-related Src family tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Frk (fyn related Src family tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : FRK (fyn related Src family tyrosine kinase)
Canis lupus familiaris (dog) : FRK (fyn related Src family tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Frk (fyn related Src family tyrosine kinase)
Sus scrofa (pig) : FRK (fyn related Src family tyrosine kinase)
Chlorocebus sabaeus (African green monkey) : FRK (fyn related Src family tyrosine kinase)
Heterocephalus glaber (naked mole-rat) : Frk (fyn related Src family tyrosine kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl6115,931,149 - 116,060,891 (-)EnsemblGRCh38hg38GRCh38
GRCh386115,931,149 - 116,100,739 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376116,262,691 - 116,397,360 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366116,369,386 - 116,488,614 (-)NCBINCBI36hg18NCBI36
Build 346116,369,386 - 116,488,614NCBI
Celera6117,005,260 - 117,124,941 (-)NCBI
Cytogenetic Map6q22.1NCBI
HuRef6113,842,168 - 113,962,110 (-)NCBIHuRef
CHM1_16116,525,566 - 116,645,735 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on FRK
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734122
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.