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Gene: UTRN (utrophin) Homo sapiens
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Symbol: UTRN
Name: utrophin
Description: Exhibits cytoskeletal protein binding activity; integrin binding activity; and protein kinase binding activity. Involved in positive regulation of cell-matrix adhesion. Localizes to several cellular components, including the cytoplasm; filopodium membrane; and nucleoplasm. Colocalizes with the contractile ring. Biomarker of ovarian cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DMDL; DRP; DRP-1; DRP1; dystrophin-related protein 1; FLJ23678
Orthologs:
Mus musculus (house mouse) : Utrn (utrophin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Utrn (utrophin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Utrn (utrophin)
Pan paniscus (bonobo/pygmy chimpanzee) : UTRN (utrophin)
Canis lupus familiaris (dog) : UTRN (utrophin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Utrn (utrophin)
Sus scrofa (pig) : UTRN (utrophin)
Chlorocebus sabaeus (green monkey) : UTRN (utrophin)
Heterocephalus glaber (naked mole-rat) : Utrn (utrophin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl6144,285,701 - 144,853,034 (+)Ensembl
GRCh386144,284,955 - 144,853,034 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376144,606,434 - 145,174,170 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366144,654,566 - 145,215,863 (+)NCBINCBI36hg18NCBI36
Build 346144,654,657 - 145,209,657NCBI
Celera6145,353,235 - 145,914,469 (+)NCBI
Cytogenetic Map6q24.2NCBI
HuRef6142,176,382 - 142,737,622 (+)NCBIHuRef
CHM1_16144,875,601 - 145,437,493 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on UTRN
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731341
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.