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lutein - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:lutein
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Accession:CHEBI:28838 term browser browse the term
Definition:A carotenol that has formula C40H56O2.
Synonyms:exact_synonym: (3R,3'R,6'R)-beta,epsilon-carotene-3,3'-diol
 related_synonym: (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL;   Bo-Xan;   E 161b;   Formula=C40H56O2;   InChI=1S/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-25,35-37,41-42H,26-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+/t35-,36+,37-/m0/s1;   InChIKey=KBPHJBAIARWVSC-RGZFRNHPSA-N;   SMILES=CC(\\C=C\\C=C(C)\\C=C\\[C@H]1C(C)=C[C@H](O)CC1(C)C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)C[C@@H](O)CC1(C)C;   Xanthophyll
 alt_id: CHEBI:27324;   CHEBI:43817;   CHEBI:6576
 xref: CAS:127-40-2;   DrugBank:DB00137;   Drug_Central:4145;   HMDB:HMDB0003233;   KEGG:C08601;   KNApSAcK:C00003776;   LIPID_MAPS_instance:LMPR01070274
 xref_mesh: MESH:D014975
 xref: MetaCyc:CPD1F-119;   PDBeChem:LUT;   PMID:10714278;   PMID:14670087;   PMID:23543147;   PMID:24451312;   Reaxys:2068550;   Wikipedia:Lutein

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lutein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 multiple interactions
decreases expression 		ISO [Cisplatin co-treated with Lutein] results in decreased expression of ALS2 mRNA; [Cisplatin co-treated with Lutein] results in increased expression of ALS2 mRNA
Lutein results in decreased expression of ALS2 mRNA 		CTD PMID:24865317 NCBI chr 9:68,107,310...68,180,192
Ensembl chr 9:60,613,167...60,670,737 		JBrowse link
G Apc APC regulator of WNT signaling pathway multiple interactions ISO [Cisplatin co-treated with Lutein] results in increased expression of APC mRNA CTD PMID:24865317 NCBI chr18:26,138,382...26,196,021
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Aqr aquarius intron-binding spliceosomal factor decreases expression
multiple interactions 		ISO Lutein results in decreased expression of AQR mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of AQR mRNA 		CTD PMID:24865317 NCBI chr 3:121,329,287...121,399,375
Ensembl chr 3:100,874,987...100,945,044 		JBrowse link
G Atr ATR serine/threonine kinase multiple interactions
decreases expression 		ISO [Cisplatin co-treated with Lutein] results in decreased expression of ATR mRNA
Lutein results in decreased expression of ATR mRNA 		CTD PMID:24865317 NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Lutein results in increased expression of BAX protein CTD PMID:17455471 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Lutein results in decreased expression of BCL2 protein CTD PMID:17455471 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO Lutein results in increased expression of BCL2L1 protein CTD PMID:10750663 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bco2 beta-carotene oxygenase 2 increases metabolic processing
multiple interactions
affects metabolic processing 		ISO BCO2 protein results in increased metabolism of Lutein
[BCO2 protein affects the metabolism of Lutein] which results in increased abundance of 3'-dehydrolutein; [BCO2 protein results in increased metabolism of Lutein] which results in increased chemical synthesis of apocarotenal metabolite 		CTD PMID:21106934 NCBI chr 8:59,778,571...59,803,597
Ensembl chr 8:50,882,181...50,915,467 		JBrowse link
G Cat catalase multiple interactions ISO Lutein inhibits the reaction [deoxynivalenol results in increased expression of CAT protein] CTD PMID:20347963 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Lutein results in decreased expression of CCND1 protein CTD PMID:17718427 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression ISO Lutein results in increased expression of CCS mRNA CTD PMID:24865317 NCBI chr 1:211,543,192...211,564,354
Ensembl chr 1:202,113,804...202,134,915 		JBrowse link
G Cfd complement factor D decreases expression
decreases secretion 		ISO Lutein results in decreased expression of CFD mRNA
Lutein results in decreased secretion of CFD protein 		CTD PMID:26504594 NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Ckb creatine kinase B multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in increased activity of CKB protein] CTD PMID:34435724 NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Ctsb cathepsin B increases expression
multiple interactions 		ISO Lutein results in increased expression of CTSB mRNA
Cisplatin inhibits the reaction [Lutein results in increased expression of CTSB mRNA] 		CTD PMID:24865317 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions
decreases expression 		ISO [Cisplatin co-treated with Lutein] results in decreased expression of CYBA mRNA
Lutein results in decreased expression of CYBA mRNA 		CTD PMID:24865317 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Des desmin multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in decreased expression of DES protein] CTD PMID:34435724 NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression
multiple interactions 		ISO Lutein results in decreased expression of ERCC2 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of ERCC2 mRNA 		CTD PMID:24865317 NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor decreases expression ISO Lutein results in decreased expression of ERCC6 mRNA CTD PMID:24865317 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 decreases expression ISO Lutein results in decreased expression of FMO2 mRNA CTD PMID:24865317 NCBI chr13:77,755,131...77,777,597
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Gab1 GRB2-associated binding protein 1 decreases expression
multiple interactions 		ISO Lutein results in decreased expression of GAB1 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of GAB1 mRNA 		CTD PMID:24865317 NCBI chr19:44,035,693...44,143,617
Ensembl chr19:27,131,262...27,239,236 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression 		ISO Cisplatin inhibits the reaction [Lutein results in increased expression of GPX1 mRNA]; Lutein inhibits the reaction [Lipopolysaccharides results in decreased expression of GPX1 mRNA] CTD PMID:22040935 PMID:24865317 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Lutein co-treated with Cisplatin] results in increased expression of GPX2 mRNA CTD PMID:24865317 NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of GPX3 mRNA CTD PMID:24865317 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression
multiple interactions 		ISO Lutein results in increased expression of GSR mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of GSR mRNA 		CTD PMID:24865317 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of GSTK1 mRNA CTD PMID:24865317 NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:71,118,896...71,123,292 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression 		ISO arsenic trioxide promotes the reaction [Lutein results in increased expression of HMOX1 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of HMOX1 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of HMOX1 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of HMOX1 protein]
Lutein results in increased expression of HMOX1 mRNA; Lutein results in increased expression of HMOX1 protein 		CTD PMID:25815309 PMID:26187899 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions
decreases expression 		ISO [Cisplatin co-treated with Lutein] results in decreased expression of IDH1 mRNA
Lutein results in decreased expression of IDH1 mRNA 		CTD PMID:24865317 NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Ift172 intraflagellar transport 172 multiple interactions
decreases expression 		ISO [Cisplatin co-treated with Lutein] results in decreased expression of IFT172 mRNA
Lutein results in decreased expression of IFT172 mRNA 		CTD PMID:24865317 NCBI chr 6:30,801,841...30,841,239
Ensembl chr 6:25,081,980...25,120,860 		JBrowse link
G Ins1 insulin 1 multiple interactions
decreases expression 		EXP [Lutein co-treated with alpha-Tocopherol] results in decreased expression of INS1 protein; [Lutein co-treated with Ascorbic Acid] results in decreased expression of INS1 protein
Lutein results in decreased expression of INS1 protein 		CTD PMID:12949374 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Kif9 kinesin family member 9 multiple interactions
increases expression 		ISO Lutein promotes the reaction [Cisplatin results in decreased expression of KIF9 mRNA]
Lutein results in increased expression of KIF9 mRNA 		CTD PMID:24865317 NCBI chr 8:119,338,014...119,406,632
Ensembl chr 8:110,459,383...110,505,252 		JBrowse link
G Mb myoglobin increases expression ISO Lutein results in increased expression of MB mRNA CTD PMID:24865317 NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 multiple interactions
increases expression 		ISO arsenic trioxide promotes the reaction [Lutein results in increased expression of MGST1 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of MGST1 mRNA] CTD PMID:25815309 PMID:26187899 NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
G Miat myocardial infarction associated transcript multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in increased expression of MIAT] CTD PMID:34435724 NCBI chr12:50,075,026...50,090,259 JBrowse link
G Mir200a microRNA 200a multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in decreased expression of MIR200A mRNA] CTD PMID:34435724 NCBI chr 5:171,930,717...171,930,805 JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression 		ISO
EXP 		arsenic trioxide promotes the reaction [Lutein results in increased expression of NFE2L2 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of NFE2L2 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NFE2L2 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NFE2L2 protein]; Lutein results in increased expression of and affects the localization of NFE2L2 protein
Lutein results in increased expression of NFE2L2 mRNA; Lutein results in increased expression of NFE2L2 protein
Lutein inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 protein] 		CTD PMID:25815309 PMID:26187899 PMID:34435724 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ngb neuroglobin increases expression ISO Lutein results in increased expression of NGB mRNA CTD PMID:24865317 NCBI chr 6:112,475,332...112,480,786
Ensembl chr 6:106,744,378...106,749,830 		JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions
decreases expression 		ISO [Cisplatin co-treated with Lutein] results in decreased expression of NOX4 mRNA
Lutein results in decreased expression of NOX4 mRNA 		CTD PMID:24865317 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Noxo1 NADPH oxidase organizer 1 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of NOXO1 mRNA CTD PMID:24865317 NCBI chr10:14,226,473...14,230,541
Ensembl chr10:13,721,473...13,726,061 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression 		ISO [Cisplatin co-treated with Lutein] results in increased expression of NQO1 mRNA; arsenic trioxide promotes the reaction [Lutein results in increased expression of NQO1 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of NQO1 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NQO1 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NQO1 protein]
Lutein results in increased expression of NQO1 mRNA; Lutein results in increased expression of NQO1 protein 		CTD PMID:24865317 PMID:25815309 PMID:26187899 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nudt15 nudix hydrolase 15 decreases expression
multiple interactions 		ISO Lutein results in decreased expression of NUDT15 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of NUDT15 mRNA 		CTD PMID:24865317 NCBI chr15:55,117,312...55,123,983
Ensembl chr15:48,709,700...48,747,363 		JBrowse link
G Nxn nucleoredoxin increases expression
multiple interactions 		ISO Lutein results in increased expression of NXN mRNA
Lutein inhibits the reaction [Cisplatin results in increased expression of NXN mRNA] 		CTD PMID:24865317 NCBI chr10:61,607,557...61,745,807
Ensembl chr10:61,110,020...61,248,251 		JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of PARK7 mRNA CTD PMID:24865317 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B multiple interactions
decreases expression 		ISO [Cisplatin co-treated with Lutein] results in decreased expression of PPP1R15B mRNA
Lutein results in decreased expression of PPP1R15B mRNA 		CTD PMID:24865317 NCBI chr13:47,130,000...47,137,805
Ensembl chr13:44,577,932...44,585,737 		JBrowse link
G Prdx4 peroxiredoxin 4 increases expression ISO Lutein results in increased expression of PRDX4 mRNA CTD PMID:24865317 NCBI chr  X:43,876,374...43,893,815
Ensembl chr  X:40,026,651...40,044,066 		JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression ISO Lutein results in decreased expression of PRDX5 mRNA CTD PMID:24865317 NCBI chr 1:213,529,042...213,532,787
Ensembl chr 1:204,099,826...204,114,268 		JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions
decreases expression 		ISO [Cisplatin co-treated with Lutein] results in decreased expression of PRDX6 mRNA
Lutein results in decreased expression of PRDX6 mRNA 		CTD PMID:24865317 NCBI chr13:76,062,082...76,072,631
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of PTGS1 mRNA CTD PMID:24865317 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Lutein inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein] CTD PMID:20347963 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Lutein inhibits the reaction [deoxynivalenol affects the localization of RELA protein]; Lutein inhibits the reaction [deoxynivalenol results in increased expression of RELA protein] CTD PMID:20347963 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions
decreases expression 		ISO [Cisplatin co-treated with Lutein] results in decreased expression of SCD1 mRNA
Lutein results in decreased expression of SCD1 mRNA 		CTD PMID:24865317 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression 		ISO Lutein inhibits the reaction [Lipopolysaccharides results in decreased expression of SOD1 mRNA]
Lutein results in increased expression of SOD1 mRNA 		CTD PMID:22040935 PMID:24865317 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression 		ISO [Cisplatin co-treated with Lutein] results in decreased expression of SOD2 mRNA; Lutein inhibits the reaction [Lipopolysaccharides results in decreased expression of SOD2 mRNA]
Lutein results in decreased expression of SOD2 mRNA 		CTD PMID:22040935 PMID:24865317 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions
decreases expression 		ISO [Cisplatin co-treated with Lutein] results in decreased expression of SOD3 mRNA
Lutein results in decreased expression of SOD3 mRNA 		CTD PMID:24865317 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions
decreases expression 		ISO [Cisplatin co-treated with Lutein] results in decreased expression of SRXN1 mRNA
Lutein results in decreased expression of SRXN1 mRNA 		CTD PMID:24865317 NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Tnnt2 troponin T2, cardiac type multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in decreased expression of TNNT2 protein] CTD PMID:34435724 NCBI chr13:49,819,123...49,837,125
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in decreased expression of TXN protein] CTD PMID:34435724 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txnip thioredoxin interacting protein multiple interactions EXP Lutein inhibits the reaction [Isoproterenol results in increased expression of TXNIP protein] CTD PMID:34435724 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases expression
multiple interactions 		ISO Lutein results in decreased expression of TXNRD1 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of TXNRD1 mRNA 		CTD PMID:24865317 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Ucp3 uncoupling protein 3 increases expression ISO Lutein results in increased expression of UCP3 mRNA CTD PMID:24865317 NCBI chr 1:164,227,910...164,240,893
Ensembl chr 1:154,815,777...154,828,762 		JBrowse link
G Vim vimentin increases expression ISO Lutein results in increased expression of VIM mRNA CTD PMID:24865317 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Xirp1 xin actin-binding repeat containing 1 increases expression ISO Lutein results in increased expression of XIRP1 mRNA CTD PMID:24865317 NCBI chr 8:128,625,111...128,635,011
Ensembl chr 8:119,747,419...119,757,349 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      application 19697
        food additive 16851
          food colouring 12072
            lutein 61
              lutein 5,6-epoxide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    main group molecular entity 19824
                      s-block molecular entity 19658
                        hydrogen molecular entity 19640
                          hydrides 19145
                            organic hydride 18698
                              organic fundamental parent 18698
                                hydrocarbon 18446
                                  terpene 14074
                                    tetraterpene 610
                                      carotene 610
                                        carotenoid 610
                                          carotenoid beta-end derivative 275
                                            alpha-carotene 62
                                              (6'R)-beta,epsilon-carotene 61
                                                lutein 61
                                                  lutein 5,6-epoxide 0
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