ONTOLOGY REPORT - ANNOTATIONS
Term: ubiquitin protein ligase activity
Accession: GO:0061630
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Definition: Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S = X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
Comment: This enzyme catalyzes a transferase reaction.
Synonyms: exact_synonym: protein ubiquitination activity; ubiquitin ligase activity
related_synonym: E3; ER-associated E3 ligase
alt_id: GO:0090302; GO:0090622; GO:1904264; GO:1904822
xref: Reactome:R-HSA-183036 "Ubiquitination of stimulated EGFR (CBL:GRB2)"; Reactome:R-HSA-9685195 "SARS-CoV-1 9b recruits ITCH to MAVS"; Reactome:R-HSA-9686920 "PELI1 ubiquitinates RIPK3 at K363"; Reactome:R-HSA-9686969 "APC/C:Cdh1 polyubiquitinates SKP2"; Reactome:R-HSA-9705738 "SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7"; Reactome:R-HSA-9706354 "Ubiquitination of FLT3"; Reactome:R-HSA-9706356 "CBL mutants don't ubiquitinate FLT3"; Reactome:R-HSA-9708517 "FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2))"; Reactome:R-HSA-9733316 "p-Y-CBL autoubiquitinates and multiubiquitinates p-Y561-CSF1R in CSF1 dimer:p-Y561-CSF1R dimer:p-Y-CBL"; Reactome:R-HSA-9755304 "MUL1 ubiquitinates UBXN7"; Reactome:R-HSA-9755505 "KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2"; Reactome:R-HSA-9759154 "TRIM21 ubiquitinates SQSTM1"; Reactome:R-HSA-9759172 "KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer"; Reactome:R-HSA-9762091 "NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1"; Reactome:R-HSA-9766645 "CUL3:RBX1 ubiquitinates KEAP1"; Reactome:R-HSA-990526 "Recruitment of ITCH and K48 ubiquitination of MAVS"; reactome:R-HSA-1225956 "Inefficient ubiquitination of ligand-responsive p-6Y-EGFR mutants by p-Y371-CBL"; reactome:R-HSA-1504190 "DVL is ubiquitinated by CUL3:KLHL12:RBX1"; reactome:R-HSA-201445 "Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8"; reactome:R-HSA-3322429 "XIAP monoubiquinates TLE"; reactome:R-HSA-3640861 "RNF146 ubiquitinates ADP-ribosylated AXIN"; reactome:R-HSA-4608852 "SMURF1/2 ubiquitinates PRICKLE1"; reactome:R-HSA-4641129 "AXIN is ubiquitinated by SMURF2"; reactome:R-HSA-4641159 "DVL1 is ubiquitinated by HECW1"; reactome:R-HSA-4641246 "ZNRF3 autoubiquitinates to promote its internalization"; reactome:R-HSA-4641253 "ZNRF3 ubiquitinates FZD to promote its downregulation"; reactome:R-HSA-5246693 "APC is K63-polyubiquitinated"; reactome:R-HSA-5610737 "NUMB:ITCH bind and ubiquitnate GLI1"; reactome:R-HSA-5632648 "SMURF1/2 ubiquitinates PTCH1"; reactome:R-HSA-5635856 "SPOP:CUL3:RBX1 ubiquitinates GLI2,3"; reactome:R-HSA-5635864 "NUMB:ITCH ubiquitinates GLI1"; reactome:R-HSA-5654672 "CBL ubiquitinates FRS2 and FGFR1"; reactome:R-HSA-5654677 "CBL ubiquitinates FRS2 and FGFR2"; reactome:R-HSA-5654679 "CBL ubiquitinates FRS2 and FGFR3"; reactome:R-HSA-5654684 "CBL ubiquitinates FRS2 and FGFR4"; reactome:R-HSA-5658424 "KBTBD7:CUL3:RBX1 ubiquitinates NF1"; reactome:R-HSA-5674022 "BRAP autoubiquitinates"; reactome:R-HSA-5682858 "RNF8 and RNF168 ubiquitinate H2AFX"; reactome:R-HSA-5684071 "RNF4 ubiquitinates MDC1"; reactome:R-HSA-5687081 "MAPK6 is ubiquitinated at the N-terminal"; reactome:R-HSA-5689111 "PARK2 autoubiquitinates"; reactome:R-HSA-5690827 "TNFAIP3 (A20) ubiquitinates RIPK1"; reactome:R-HSA-6781867 "ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II"; reactome:R-HSA-6782943 "UV-DDB ubiquitinates XPC"; reactome:R-HSA-6785361 "Monoubiquitination of FANCD2:FANCI"; reactome:R-HSA-6790487 "RNF111 ubiquitinates SUMOylated XPC"; reactome:R-HSA-6798373 "MDM2 ubiquitinates DYRK2"; reactome:R-HSA-6804253 "MDM2 ubiquitinates JMY"; reactome:R-HSA-6804441 "RNF34 or RFFL ubiquitinates phosphorylated TP53"; reactome:R-HSA-6804724 "MDM2 ubiquitinates phosphorylated MDM4"; reactome:R-HSA-6804879 "MDM2 ubiquitinates TP53"; reactome:R-HSA-6804942 "MDM2 homodimers auto-ubiquitinate"; reactome:R-HSA-6807106 "PTEN undergoes monoubiquitination"; reactome:R-HSA-6807134 "NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN"; reactome:R-HSA-68946 "Phosphorylated Orc1 is ubiquitinated while still associated with chromatin"; reactome:R-HSA-69015 "Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex"; reactome:R-HSA-8848829 "CBL autoubiquitinates"; reactome:R-HSA-8851011 "TRIM27 polyubiquitinates PTEN"; reactome:R-HSA-8854041 "SCF-FBXL7 ubiquitinates AURKA"; reactome:R-HSA-8854051 "SCF-FBXL18 ubiquitinates FBXL7"; reactome:R-HSA-8854628 "MYLIP dimer ubiquitinates VLDLR on Lys-839"; reactome:R-HSA-8866546 "RNF5 and RNF185 ubiquitinate misfolded CFTR"; reactome:R-HSA-8866856 "RNF5 and RNF185 ubiquitinate CFTR F508del"; reactome:R-HSA-8867288 "OS9:SEL1:ERAD E3 ligase:DERL2 ubiquitinates unfolded protein:(GlcNAc)2 (Man)9-5"; reactome:R-HSA-8875183 "CBL monoubiquitinates activated MET"; reactome:R-HSA-8875431 "LRIG1 undergoes ubiquitination"; reactome:R-HSA-8876258 "CBL monoubiquitinates InlB-bound MET"; reactome:R-HSA-8877003 "CBLL1 ubiqutinates the InlA-bound CDH1 complex"; reactome:R-HSA-8938773 "RNF144A polyubiquitinates PRKDC"; reactome:R-HSA-8938815 "RNF152 polyubiquitinates RRAGA"; reactome:R-HSA-8939335 "RNF181 polyubiquinates BCL10"; reactome:R-HSA-8939706 "SCF(SKP2) polyubiquitinates RUNX2"; reactome:R-HSA-8942101 "RNF20:RNF40 monoubiquitinates Histone H2B"; reactome:R-HSA-8943003 "SHPRH polyubiquitinates monoubiquitinated PCNA"; reactome:R-HSA-8943040 "HLTF polyubiquitinates monoubiquitinated PCNA"; reactome:R-HSA-8943080 "TMEM129 polyubiquitinates HLA (MHC class I heavy chain) bound to cytomegalovirus US11"; reactome:R-HSA-8948775 "MKRN1 polyubiquitinates PTEN"; reactome:R-HSA-8948832 "RNF146 polyubiquitinates PARylated PTEN"; reactome:R-HSA-8952382 "MDM2 polyubiquitinates RUNX3"; reactome:R-HSA-8952419 "SMURFs ubiquitinate RUNX3"; reactome:R-HSA-8953946 "PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11"; reactome:R-HSA-8956026 "CUL9:RBX1 ubiquitinates BIRC5"; reactome:R-HSA-8956684 "ITCH polyubiquitinates TP73"; reactome:R-HSA-9008076 "WWP1 polyubiquitinates RUNX2"; reactome:R-HSA-9009308 "STUB1 polyubiquitinates RUNX2"; reactome:R-HSA-9009403 "SMURF1 polyubiquitinates RUNX2"; reactome:R-HSA-9011300 "ZSWIM8 ubiquitinates ROBO3.1"; reactome:R-HSA-9021523 "WWP2 ubiquitinates NOTCH3"; reactome:R-HSA-9033485 "PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11"; reactome:R-HSA-934604 "Phosphorylated SPRY2 is ubiquitinated by CBL"; reactome:R-HSA-936462 "PIN1 mediated IRF3 degradation"; reactome:R-HSA-936475 "Negative regulation of DDX58/IFIH1 signaling by RNF216"; reactome:R-HSA-9604629 "FBXW7 promotes ubiquitination of p-NICD4"
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AL110118.1
novel protein
enables
IEA
InterPro
GO_REF:0000002
Ensembl chr14:93,184,973...93,218,586
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AMFR
autocrine motility factor receptor
enables
TAS IBA IEA IMP IDA
(PMID:24424410) (PMID:37119330) (PMID:17310145), (PMID:24424410), (PMID:28604676)
Reactome GO_Central TreeGrafter UniProt ParkinsonsUK-UCL
PMID:17310145 PMID:24424410 PMID:28604676 PMID:37119330
GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-8867288
NCBI chr16:56,361,452...56,425,545
Ensembl chr16:56,361,452...56,425,545
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ANAPC11
anaphase promoting complex subunit 11
enables
IDA IBA IEA
(PMID:10230407)
MGI GO_Central InterPro
PMID:10230407
GO_REF:0000002 GO_REF:0000033
NCBI chr17:81,890,790...81,900,533
Ensembl chr17:81,890,790...81,900,991
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ANKIB1
ankyrin repeat and IBR domain containing 1
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 7:92,245,974...92,401,383
Ensembl chr 7:92,245,974...92,401,383
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AREL1
apoptosis resistant E3 ubiquitin protein ligase 1
enables
IDA IBA
(PMID:25752577)
UniProt GO_Central
PMID:25752577
GO_REF:0000033
NCBI chr14:74,661,256...74,713,080
Ensembl chr14:74,653,437...74,713,117
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ARIH1
ariadne RBR E3 ubiquitin protein ligase 1
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987
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ARIH2
ariadne RBR E3 ubiquitin protein ligase 2
enables
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr 3:48,918,842...48,986,382
Ensembl chr 3:48,918,821...48,986,382
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ARK2C
arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C
enables
IEA IBA
Ensembl TreeGrafter GO_Central InterPro
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr18:46,334,018...46,463,140
Ensembl chr18:46,326,809...46,463,140
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ARK2N
arkadia (RNF111) N-terminal like PKA signaling regulator 2N
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr18:46,173,553...46,266,992
Ensembl chr18:46,173,553...46,266,992
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ASB1
ankyrin repeat and SOCS box containing 1
contributes_to
IDA
(PMID:16325183)
UniProt
PMID:16325183
NCBI chr 2:238,426,927...238,452,250
Ensembl chr 2:238,426,742...238,452,250
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ASB12
ankyrin repeat and SOCS box containing 12
contributes_to
IDA IBA
(PMID:16325183)
UniProt GO_Central
PMID:16325183
GO_REF:0000033
NCBI chr X:64,224,194...64,230,607
Ensembl chr X:64,224,194...64,230,607
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ASB2
ankyrin repeat and SOCS box containing 2
contributes_to
IDA
(PMID:16325183)
UniProt
PMID:16325183
NCBI chr14:93,934,166...93,976,570
Ensembl chr14:93,934,166...93,976,739
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ASB4
ankyrin repeat and SOCS box containing 4
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 7:95,470,656...95,551,317
Ensembl chr 7:95,478,444...95,540,233
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BFAR
bifunctional apoptosis regulator
enables
IDA IBA IEA
(PMID:21068390)
ParkinsonsUK-UCL GO_Central TreeGrafter
PMID:21068390
GO_REF:0000033 GO_REF:0000118
NCBI chr16:14,632,951...14,669,236
Ensembl chr16:14,632,931...14,669,236
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BIRC2
baculoviral IAP repeat containing 2
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670
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BIRC3
baculoviral IAP repeat containing 3
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
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BIRC7
baculoviral IAP repeat containing 7
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr20:63,235,905...63,240,495
Ensembl chr20:63,235,883...63,240,495
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BIRC8
baculoviral IAP repeat containing 8
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr19:53,289,601...53,291,434
Ensembl chr19:53,289,664...53,291,131 Ensembl chr19:53,289,664...53,291,131
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BRAP
BRCA1 associated protein
enables
TAS IBA IEA IDA
(PMID:14724641)
Reactome GO_Central TreeGrafter MGI
PMID:14724641
GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-5674022
NCBI chr12:111,642,146...111,685,956
Ensembl chr12:111,642,146...111,685,956
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BSPRY
B-box and SPRY domain containing
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 9:113,349,541...113,371,222
Ensembl chr 9:113,349,541...113,371,233
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BTNL9
butyrophilin like 9
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr 5:181,040,266...181,061,521
Ensembl chr 5:181,040,225...181,061,521
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BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr10:101,354,048...101,557,313
Ensembl chr10:101,354,033...101,557,321
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C10orf90
chromosome 10 open reading frame 90
enables
ISS
UniProt
GO_REF:0000024
NCBI chr10:126,424,997...126,670,693
Ensembl chr10:126,424,997...126,798,708
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CBL
Cbl proto-oncogene
enables
ISO IBA TAS IEA
RGD GO_Central Reactome Ensembl
PMID:17675467
GO_REF:0000033 GO_REF:0000107 RGD:11576315 Reactome:R-HSA-183036 Reactome:R-HSA-8848829 Reactome:R-HSA-8875183 Reactome:R-HSA-8876258 Reactome:R-HSA-934604 Reactome:R-HSA-9706354 Reactome:R-HSA-9706356
NCBI chr11:119,206,339...119,308,149
Ensembl chr11:119,206,298...119,313,926
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CBLB
Cbl proto-oncogene B
enables
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552
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CBLC
Cbl proto-oncogene C
enables
IDA IBA
(PMID:14661060)
BHF-UCL GO_Central
PMID:14661060
GO_REF:0000033
NCBI chr19:44,777,869...44,800,652
Ensembl chr19:44,777,869...44,800,652
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CBLL1
Cbl proto-oncogene like 1
enables
IEA IBA
Ensembl TreeGrafter GO_Central InterPro
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr 7:107,744,142...107,761,667
Ensembl chr 7:107,743,073...107,761,667
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CBLL2
Cbl proto-oncogene like 2
enables
IEA IBA
InterPro GO_Central
GO_REF:0000002 GO_REF:0000033
NCBI chr X:22,272,913...22,274,461
Ensembl chr X:22,272,913...22,274,461
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CCAR1
cell division cycle and apoptosis regulator 1
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr10:68,721,239...68,792,377
Ensembl chr10:68,721,012...68,792,377
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CCNB1IP1
cyclin B1 interacting protein 1
enables
IEA
InterPro
GO_REF:0000002
NCBI chr14:20,311,370...20,333,279
Ensembl chr14:20,311,368...20,333,312
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CCNC
cyclin C
contributes_to
ISO
RGD
PMID:12149480
RGD:2304264
NCBI chr 6:99,542,387...99,568,814
Ensembl chr 6:99,542,387...99,568,825
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CDC42
cell division cycle 42
enables
IDA
(PMID:21435037)
AgBase
PMID:21435037
NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,052,627...22,101,360
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CDK8
cyclin dependent kinase 8
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr13:26,254,129...26,405,238
Ensembl chr13:26,254,104...26,420,982
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CHFR
checkpoint with forkhead and ring finger domains
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr12:132,832,356...132,887,618
Ensembl chr12:132,822,187...132,956,304
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COP1
COP1 E3 ubiquitin ligase
enables
IEA IBA IMP
(PMID:19805145)
InterPro TreeGrafter GO_Central UniProt
PMID:19805145
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr 1:175,944,831...176,207,286
Ensembl chr 1:175,944,831...176,207,286
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CUL3
cullin 3
enables
IDA
(PMID:14528312)
UniProt
PMID:14528312
NCBI chr 2:224,470,150...224,585,363
Ensembl chr 2:224,470,150...224,585,397
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CUL4A
cullin 4A
enables
IDA
(PMID:20870715)
UniProt
PMID:20870715
NCBI chr13:113,208,193...113,267,108
Ensembl chr13:113,208,193...113,267,108
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CUL9
cullin 9
enables
TAS
Reactome
Reactome:R-HSA-8956026
NCBI chr 6:43,182,196...43,224,587
Ensembl chr 6:43,182,184...43,224,587
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DCST1
DC-STAMP domain containing 1
enables
IDA
(PMID:27782195)
UniProt
PMID:27782195
NCBI chr 1:155,033,806...155,050,930
Ensembl chr 1:155,033,824...155,050,930
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DTX1
deltex E3 ubiquitin ligase 1
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr12:113,056,730...113,098,025
Ensembl chr12:113,056,730...113,098,028
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DTX2
deltex E3 ubiquitin ligase 2
enables
IEA IBA
UniProt TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000104 GO_REF:0000118
NCBI chr 7:76,461,709...76,505,991
Ensembl chr 7:76,461,676...76,505,995
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DTX3
deltex E3 ubiquitin ligase 3
enables
IEA
UniProt
GO_REF:0000104
NCBI chr12:57,604,824...57,609,802
Ensembl chr12:57,604,622...57,609,804
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DTX4
deltex E3 ubiquitin ligase 4
enables
IDA IBA
(PMID:35793002)
UniProt GO_Central
PMID:35793002
GO_REF:0000033
NCBI chr11:59,171,430...59,208,588
Ensembl chr11:59,171,430...59,208,588
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DZIP3
DAZ interacting zinc finger protein 3
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 3:108,589,510...108,694,840
Ensembl chr 3:108,589,705...108,694,840
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EIF2AK4
eukaryotic translation initiation factor 2 alpha kinase 4
enables
IEA
InterPro
GO_REF:0000002
NCBI chr15:39,934,115...40,035,591
Ensembl chr15:39,934,115...40,035,591
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ERMAP
erythroblast membrane associated protein (Scianna blood group)
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr 1:42,817,122...42,844,991
Ensembl chr 1:42,817,122...42,844,991
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FANCF
FA complementation group F
contributes_to
ISO
(PMID:21915857)
MGI
PMID:21915857
NCBI chr11:22,622,533...22,625,823
Ensembl chr11:22,622,533...22,625,823
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FANCL
FA complementation group L
enables
IEA IBA IDA
(PMID:19589784)
Ensembl GO_Central UniProt MGI
PMID:19589784
GO_REF:0000033 GO_REF:0000107 GO_REF:0000117
NCBI chr 2:58,159,243...58,241,380
Ensembl chr 2:58,159,243...58,241,410
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FBXL22
F-box and leucine rich repeat protein 22
enables
IDA
(PMID:22972877)
MGI
PMID:22972877
NCBI chr15:63,597,387...63,608,516
Ensembl chr15:63,597,353...63,602,428
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FBXO17
F-box protein 17
contributes_to
IBA
GO_Central
GO_REF:0000033
NCBI chr19:38,941,401...38,975,742
Ensembl chr19:38,941,401...38,975,742
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FBXO2
F-box protein 2
contributes_to
IBA
GO_Central
GO_REF:0000033
NCBI chr 1:11,648,387...11,654,429
Ensembl chr 1:11,637,018...11,655,785
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FBXO27
F-box protein 27
enables contributes_to
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr19:39,005,842...39,032,549
Ensembl chr19:38,990,714...39,032,785
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FBXO30
F-box protein 30
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 6:145,793,502...145,814,795
Ensembl chr 6:145,793,502...145,814,795
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FBXO4
F-box protein 4
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 5:41,925,281...42,040,404
Ensembl chr 5:41,925,254...41,941,743
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FBXO40
F-box protein 40
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 3:121,593,379...121,630,295
Ensembl chr 3:121,593,379...121,630,295
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FBXO44
F-box protein 44
contributes_to enables
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr 1:11,654,407...11,663,327
Ensembl chr 1:11,654,375...11,663,327
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FBXO6
F-box protein 6
enables contributes_to
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr 1:11,664,200...11,674,354
Ensembl chr 1:11,664,200...11,674,354
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FBXW11
F-box and WD repeat domain containing 11
enables contributes_to
IEA ISO
(PMID:11896578)
Ensembl MGI
PMID:11896578
GO_REF:0000107
NCBI chr 5:171,861,549...172,006,638
Ensembl chr 5:171,861,549...172,006,873
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G2E3
G2/M-phase specific E3 ubiquitin protein ligase
enables
ISO
(PMID:18511420)
MGI
PMID:18511420
NCBI chr14:30,559,158...30,620,064
Ensembl chr14:30,559,158...30,620,064
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GID4
GID complex subunit 4 homolog
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr17:18,039,408...18,068,405
Ensembl chr17:18,039,408...18,068,405
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HACE1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 6:104,728,094...104,859,919
Ensembl chr 6:104,728,094...104,859,919
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HECTD1
HECT domain E3 ubiquitin protein ligase 1
enables
ISS IEA IBA IDA
(PMID:33711283)
FlyBase TreeGrafter GO_Central UniProt InterPro
PMID:33711283
GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118
NCBI chr14:31,100,117...31,207,793
Ensembl chr14:31,100,117...31,207,804
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HECTD2
HECT domain E3 ubiquitin protein ligase 2
enables
IEA IBA
InterPro GO_Central TreeGrafter
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr10:91,409,235...91,514,820
Ensembl chr10:91,409,280...91,514,829
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HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
enables
TAS IEA IBA
Reactome TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-4641159
NCBI chr 7:43,112,647...43,566,001
Ensembl chr 7:43,112,629...43,566,001
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HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
enables
IEA IBA
InterPro GO_Central
GO_REF:0000002 GO_REF:0000033
NCBI chr 2:196,194,072...196,593,554
Ensembl chr 2:196,189,099...196,593,684
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HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
enables
IDA IBA
(PMID:20304803)
UniProt GO_Central
PMID:20304803
GO_REF:0000033
NCBI chr15:28,111,040...28,322,179
Ensembl chr15:28,111,040...28,322,179
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HERC2P3
HERC2 pseudogene 3
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr15:20,408,396...20,506,180
Ensembl chr15:20,431,093...20,505,462 Ensembl chr15:20,431,093...20,505,462
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HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
enables
IEA IBA
InterPro GO_Central
GO_REF:0000002 GO_REF:0000033
NCBI chr 4:88,523,843...88,708,539
Ensembl chr 4:88,592,434...88,708,541 Ensembl chr 4:88,592,434...88,708,541
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HERC4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr10:67,921,905...68,075,283
Ensembl chr10:67,921,899...68,075,301
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HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5
enables
IDA IBA IEA
(PMID:15331633)
MGI GO_Central InterPro
PMID:15331633
GO_REF:0000002 GO_REF:0000033
NCBI chr 4:88,457,119...88,506,163
Ensembl chr 4:88,457,119...88,506,163
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HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 4:88,378,852...88,443,097
Ensembl chr 4:88,378,739...88,443,097
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HLTF
helicase like transcription factor
enables
EXP
(PMID:18316726), (PMID:18719106), (PMID:19723507), (PMID:21396873), (PMID:26350214)
Reactome
PMID:18316726 PMID:18719106 PMID:19723507 PMID:21396873 PMID:26350214
NCBI chr 3:149,030,063...149,086,533
Ensembl chr 3:149,030,127...149,086,554
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HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
enables
IDA IEA IBA IMP
(PMID:30217973) (PMID:26214738)
UniProt TreeGrafter GO_Central
PMID:26214738 PMID:30217973
GO_REF:0000033 GO_REF:0000118
NCBI chr X:53,532,096...53,686,719
Ensembl chr X:53,532,096...53,686,752
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IRF2BP1
interferon regulatory factor 2 binding protein 1
enables
IDA
(PMID:18671972)
ARUK-UCL
PMID:18671972
NCBI chr19:45,883,608...45,886,141
Ensembl chr19:45,883,608...45,886,141
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IRF2BPL
interferon regulatory factor 2 binding protein like
enables
IDA
(PMID:29374064)
UniProt
PMID:29374064
NCBI chr14:77,024,543...77,028,708
Ensembl chr14:77,024,543...77,028,708
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ITCH
itchy E3 ubiquitin protein ligase
enables
IEA IMP NAS IDA IBA TAS
(PMID:15051726), (PMID:22009753), (PMID:24790097) (PMID:10940313) (PMID:15678106), (PMID:17592138), (PMID:27736772), (PMID:29378950), (PMID:34927784)
InterPro UniProt TreeGrafter GO_Central Reactome
PMID:10940313 PMID:15051726 PMID:15678106 PMID:17592138 PMID:22009753 PMID:24790097 PMID:27736772 PMID:29378950 PMID:34927784 More...
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-5610737 Reactome:R-HSA-5635864 Reactome:R-HSA-8956684 Reactome:R-HSA-9685195 Reactome:R-HSA-990526
NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773
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JADE2
jade family PHD finger 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 5:134,523,952...134,583,227
Ensembl chr 5:134,524,312...134,583,230
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KCMF1
potassium channel modulatory factor 1
enables
IDA
(PMID:15581609), (PMID:34893540), (PMID:37891180), (PMID:38297121)
UniProt
PMID:15581609 PMID:34893540 PMID:37891180 PMID:38297121
NCBI chr 2:84,971,161...85,059,472
Ensembl chr 2:84,971,093...85,059,472
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LOC122513141
ring finger protein-like
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 9:137,217,494...137,219,361
Ensembl chr 9:137,217,452...137,219,361
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LONRF1
LON peptidase N-terminal domain and ring finger 1
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 8:12,721,906...12,755,526
Ensembl chr 8:12,721,906...12,756,073
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LONRF2
LON peptidase N-terminal domain and ring finger 2
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 2:100,271,875...100,322,501
Ensembl chr 2:100,271,875...100,322,501
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LONRF3
LON peptidase N-terminal domain and ring finger 3
enables
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr X:118,974,614...119,018,355
Ensembl chr X:118,974,614...119,018,355
G
LRSAM1
leucine rich repeat and sterile alpha motif containing 1
enables
IDA
(PMID:23245322)
GO_Central
PMID:23245322
NCBI chr 9:127,451,486...127,503,501
Ensembl chr 9:127,451,489...127,503,499
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LTN1
listerin E3 ubiquitin protein ligase 1
enables
IEA IBA IDA
(PMID:25578875)
InterPro GO_Central TreeGrafter UniProt Ensembl
PMID:25578875
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118
NCBI chr21:28,928,144...28,992,877
Ensembl chr21:28,928,144...28,992,956
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MAEA
macrophage erythroblast attacher, E3 ubiquitin ligase
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 4:1,289,891...1,340,137
Ensembl chr 4:1,289,887...1,340,147
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MARCHF1
membrane associated ring-CH-type finger 1
enables
IDA IEA IBA
(PMID:14722266), (PMID:18305173), (PMID:18389477), (PMID:19117940)
UniProt TreeGrafter GO_Central
PMID:14722266 PMID:18305173 PMID:18389477 PMID:19117940
GO_REF:0000033 GO_REF:0000118
NCBI chr 4:163,524,298...164,384,019
Ensembl chr 4:163,524,298...164,384,050
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MARCHF2
membrane associated ring-CH-type finger 2
enables
IMP IDA
(PMID:17980554), (PMID:31142615) (PMID:14722266)
UniProt
PMID:14722266 PMID:17980554 PMID:31142615
NCBI chr19:8,413,305...8,439,017
Ensembl chr19:8,413,270...8,439,017
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MARCHF5
membrane associated ring-CH-type finger 5
enables
IMP IBA IDA
(PMID:16874301) (PMID:16936636)
UniProt GO_Central
PMID:16874301 PMID:16936636
GO_REF:0000033
NCBI chr10:92,291,167...92,353,964
Ensembl chr10:92,291,167...92,353,964
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MARCHF6
membrane associated ring-CH-type finger 6
enables
IDA TAS
(PMID:24449766) (PMID:16373356), (PMID:25088257)
UniProt ParkinsonsUK-UCL
PMID:16373356 PMID:24449766 PMID:25088257
Reactome:R-HSA-8867288
NCBI chr 5:10,353,695...10,440,388
Ensembl chr 5:10,353,695...10,440,388
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MARCHF7
membrane associated ring-CH-type finger 7
enables
IDA
(PMID:25552655)
UniProt
PMID:25552655
NCBI chr 2:159,712,506...159,771,027
Ensembl chr 2:159,712,457...159,771,027
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MARCHF8
membrane associated ring-CH-type finger 8
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr10:45,454,585...45,594,907
Ensembl chr10:45,454,585...45,594,906
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MARVELD3
MARVEL domain containing 3
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr16:71,626,184...71,641,965
Ensembl chr16:71,626,161...71,642,114
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MDM2
MDM2 proto-oncogene
enables
IMP IBA IEA IDA TAS
(PMID:16479015), (PMID:18560357) (PMID:15314173), (PMID:17310983) (PMID:23150757)
CAFA GO_Central TreeGrafter InterPro Ensembl ARUK-UCL
PMID:15314173 PMID:16479015 PMID:17310983 PMID:18560357 PMID:23150757
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544
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MED1
mediator complex subunit 1
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr17:39,404,285...39,451,263
Ensembl chr17:39,404,285...39,451,272
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MED10
mediator complex subunit 10
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr 5:6,371,874...6,378,547
Ensembl chr 5:6,371,874...6,378,571
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MED11
mediator complex subunit 11
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12584197
GO_REF:0000107 RGD:2304263
NCBI chr17:4,731,428...4,733,607
Ensembl chr17:4,731,428...4,733,608
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MED12
mediator complex subunit 12
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr X:71,118,596...71,142,450
Ensembl chr X:71,118,543...71,144,103
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MED17
mediator complex subunit 17
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr11:93,784,282...93,814,963
Ensembl chr11:93,784,227...93,814,963
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MED18
mediator complex subunit 18
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr 1:28,329,040...28,335,965
Ensembl chr 1:28,329,002...28,335,965
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MED20
mediator complex subunit 20
contributes_to
ISO
RGD
PMID:12149480
RGD:2304264
NCBI chr 6:41,905,354...41,921,139
Ensembl chr 6:41,905,354...41,921,139
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MED21
mediator complex subunit 21
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr12:27,022,558...27,038,951
Ensembl chr12:27,022,546...27,066,343
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MED23
mediator complex subunit 23
contributes_to
ISO
RGD
PMID:12149480
RGD:2304264
NCBI chr 6:131,573,966...131,628,313
Ensembl chr 6:131,573,966...131,628,242
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MED24
mediator complex subunit 24
contributes_to
ISO
RGD
PMID:12149480
RGD:2304264
NCBI chr17:40,019,104...40,054,408
Ensembl chr17:40,019,097...40,061,215
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MED27
mediator complex subunit 27
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr 9:131,860,112...132,079,867
Ensembl chr 9:131,852,928...132,079,867
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MED30
mediator complex subunit 30
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr 8:117,520,713...117,540,262
Ensembl chr 8:117,520,713...117,540,262
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MED31
mediator complex subunit 31
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr17:6,643,311...6,651,605
Ensembl chr17:6,643,311...6,651,634
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MED6
mediator complex subunit 6
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr14:70,583,221...70,600,655
Ensembl chr14:70,581,257...70,600,690
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MED7
mediator complex subunit 7
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr 5:157,137,424...157,142,865
Ensembl chr 5:157,137,424...157,159,019
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MED8
mediator complex subunit 8
contributes_to enables
ISO IEA
RGD Ensembl
PMID:12149480
GO_REF:0000107 RGD:2304264
NCBI chr 1:43,383,917...43,389,800
Ensembl chr 1:43,383,917...43,389,808
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MEFV
MEFV innate immunity regulator, pyrin
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr16:3,242,027...3,256,633
Ensembl chr16:3,242,027...3,256,633
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MEX3C
mex-3 RNA binding family member C
enables
IDA
(PMID:22863774)
FlyBase
PMID:22863774
NCBI chr18:51,174,550...51,197,681
Ensembl chr18:51,174,550...51,218,333
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MGRN1
mahogunin ring finger 1
enables
IEA IBA
Ensembl GO_Central UniProt InterPro
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107
NCBI chr16:4,624,826...4,690,972
Ensembl chr16:4,616,493...4,690,974
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MIB1
MIB E3 ubiquitin protein ligase 1
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr18:21,704,916...21,870,953
Ensembl chr18:21,704,957...21,870,953
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MIB2
MIB E3 ubiquitin protein ligase 2
enables
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr 1:1,613,731...1,630,605
Ensembl chr 1:1,615,454...1,630,605
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MKRN1
makorin ring finger protein 1
enables
IDA IEA IBA TAS
(PMID:19536131)
FlyBase TreeGrafter GO_Central InterPro Reactome
PMID:19536131
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-8948775
NCBI chr 7:140,453,033...140,479,569
Ensembl chr 7:140,453,033...140,479,536
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MKRN2
makorin ring finger protein 2
enables
ISS IBA IEA
UniProt GO_Central InterPro Ensembl
GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr 3:12,557,087...12,583,713
Ensembl chr 3:12,557,057...12,586,208
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MKRN3
makorin ring finger protein 3
enables
ISS IBA IEA
FlyBase GO_Central InterPro
GO_REF:0000002 GO_REF:0000024 GO_REF:0000033
NCBI chr15:23,565,674...23,568,044
Ensembl chr15:23,565,674...23,630,075
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MKRN4P
makorin ring finger protein 4, pseudogene
enables
IEA IBA
InterPro GO_Central
GO_REF:0000002 GO_REF:0000033
NCBI chr X:40,834,254...40,837,807
Ensembl chr X:40,834,485...40,836,005
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MSL2
MSL complex subunit 2
enables
IEA IBA IDA
(PMID:19033443), (PMID:23874665)
InterPro GO_Central TreeGrafter UniProt
PMID:19033443 PMID:23874665
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr 3:136,148,917...136,196,335
Ensembl chr 3:136,148,917...136,197,241
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MUL1
mitochondrial E3 ubiquitin protein ligase 1
enables
IDA
(PMID:18213395), (PMID:18591963), (PMID:21597459)
UniProt
PMID:18213395 PMID:18591963 PMID:21597459
NCBI chr 1:20,499,448...20,508,151
Ensembl chr 1:20,499,448...20,508,151
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MYCBP2
MYC binding protein 2
enables
IDA IBA
(PMID:29643511)
UniProt GO_Central
PMID:29643511
GO_REF:0000033
NCBI chr13:77,044,657...77,327,094
Ensembl chr13:77,042,474...77,327,094
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MYLIP
myosin regulatory light chain interacting protein
enables
IEA IDA
(PMID:21685362)
Ensembl MGI
PMID:21685362
GO_REF:0000107
NCBI chr 6:16,129,086...16,163,887
Ensembl chr 6:16,129,086...16,148,248
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NCCRP1
NCCRP1, F-box associated domain containing
contributes_to
IBA
GO_Central
GO_REF:0000033
NCBI chr19:39,196,964...39,201,884
Ensembl chr19:39,196,964...39,201,884
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NEDD4
NEDD4 E3 ubiquitin protein ligase
enables
TAS IBA IDA
(PMID:11342538), (PMID:17116753), (PMID:17996703), (PMID:20086093), (PMID:26006083), (PMID:34880843)
Reactome GO_Central ARUK-UCL
PMID:11342538 PMID:17116753 PMID:17996703 PMID:20086093 PMID:26006083 PMID:34880843 More...
GO_REF:0000033 Reactome:R-HSA-6807134
NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660
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NEDD4L
NEDD4 like E3 ubiquitin protein ligase
enables
IEA IBA
InterPro TreeGrafter GO_Central
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540
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NEURL1
neuralized E3 ubiquitin protein ligase 1
enables
IEA IBA
Ensembl GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr10:103,493,705...103,592,546
Ensembl chr10:103,493,705...103,592,546
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NEURL1B
neuralized E3 ubiquitin protein ligase 1B
enables
ISS IBA IEA
UniProt GO_Central Ensembl
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr 5:172,641,263...172,691,540
Ensembl chr 5:172,641,263...172,691,540
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NEURL2
neuralized E3 ubiquitin protein ligase 2
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr20:45,888,634...45,891,208
Ensembl chr20:45,888,625...45,891,208
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NEURL3
neuralized E3 ubiquitin protein ligase 3
enables
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr 2:96,497,646...96,508,109
Ensembl chr 2:96,497,646...96,508,109
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NEURL4
neuralized E3 ubiquitin protein ligase 4
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr17:7,315,628...7,329,335
Ensembl chr17:7,315,628...7,329,393
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NFX1
nuclear transcription factor, X-box binding 1
enables
IDA TAS
(PMID:10500182) (PMID:15371341)
ARUK-UCL
PMID:10500182 PMID:15371341
NCBI chr 9:33,290,516...33,371,157
Ensembl chr 9:33,290,512...33,371,157
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NHLRC1
NHL repeat containing E3 ubiquitin protein ligase 1
enables
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr 6:18,120,440...18,122,677
Ensembl chr 6:18,120,440...18,122,677
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NHLRC3
NHL repeat containing 3
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr13:39,038,311...39,050,109
Ensembl chr13:39,038,306...39,050,109
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NOSIP
nitric oxide synthase interacting protein
enables
IEA
InterPro
GO_REF:0000002
NCBI chr19:49,555,468...49,580,556
Ensembl chr19:49,555,468...49,590,262
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NSMCE1
NSE1 homolog, SMC5-SMC6 complex component
enables
IEA IDA
(PMID:20864041)
UniProt
PMID:20864041
GO_REF:0000104
NCBI chr16:27,224,994...27,268,772
Ensembl chr16:27,224,994...27,268,772
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NT5C2
5'-nucleotidase, cytosolic II
enables
IDA
(PMID:36159777)
UniProt
PMID:36159777
NCBI chr10:103,088,017...103,193,272
Ensembl chr10:103,087,185...103,277,605
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PDZRN3
PDZ domain containing ring finger 3
enables
IEA IBA
Ensembl GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr 3:73,382,431...73,624,941
Ensembl chr 3:73,382,431...73,624,941
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PELI1
pellino E3 ubiquitin protein ligase 1
enables
IEA IDA IBA EXP
(PMID:29883609), (PMID:30952868)
Ensembl UniProt GO_Central TreeGrafter InterPro Reactome
PMID:29883609 PMID:30952868
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118
NCBI chr 2:64,092,652...64,144,420
Ensembl chr 2:64,092,652...64,144,420
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PELI2
pellino E3 ubiquitin protein ligase family member 2
enables
IEA IBA
InterPro GO_Central UniProt
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104
NCBI chr14:56,118,411...56,301,524
Ensembl chr14:56,117,814...56,301,524
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PELI3
pellino E3 ubiquitin protein ligase family member 3
enables
IEA IBA
InterPro TreeGrafter GO_Central
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr11:66,466,327...66,477,337
Ensembl chr11:66,466,327...66,477,337
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PEX10
peroxisomal biogenesis factor 10
enables
IDA
(PMID:24662292)
UniProt
PMID:24662292
NCBI chr 1:2,403,974...2,413,827
Ensembl chr 1:2,403,964...2,413,797
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PEX12
peroxisomal biogenesis factor 12
NOT|enables
IDA
(PMID:24662292)
UniProt
PMID:24662292
NCBI chr17:35,574,795...35,578,571
Ensembl chr17:35,574,795...35,578,863
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PEX2
peroxisomal biogenesis factor 2
enables
IDA ISS
(PMID:27597759), (PMID:34903883) (PMID:35768507)
UniProt
PMID:27597759 PMID:34903883 PMID:35768507
NCBI chr 8:76,980,258...77,001,044
Ensembl chr 8:76,980,258...77,001,044
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PJA1
praja ring finger ubiquitin ligase 1
enables
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr X:69,160,746...69,165,453
Ensembl chr X:69,160,851...69,165,521
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PJA2
praja ring finger ubiquitin ligase 2
enables
IDA
(PMID:33934390)
UniProt
PMID:33934390
NCBI chr 5:109,334,722...109,409,974
Ensembl chr 5:109,334,713...109,409,974
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PML
PML nuclear body scaffold
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827
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PPIL2
peptidylprolyl isomerase like 2
enables
IDA IEA IBA
(PMID:11435423)
MGI TreeGrafter GO_Central InterPro
PMID:11435423
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr22:21,666,012...21,700,015
Ensembl chr22:21,666,000...21,700,015
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PPP1R11
protein phosphatase 1 regulatory inhibitor subunit 11
enables
IDA
(PMID:27805901)
UniProt
PMID:27805901
NCBI chr 6:30,061,265...30,070,333
Ensembl chr 6:30,066,709...30,070,333
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PRKN
parkin RBR E3 ubiquitin protein ligase
enables
TAS IDA IBA IEA IMP NAS
(PMID:10973942), (PMID:11439185), (PMID:12150907), (PMID:12628165), (PMID:12925569), (PMID:16227987), (PMID:19229105), (PMID:19880420), (PMID:20823226), (PMID:21376232), (PMID:23685073), (PMID:23858059), (PMID:25621951) (PMID:32047033) (PMID:10973942), (PMID:18221368)
Reactome UniProt GO_Central TreeGrafter ParkinsonsUK-UCL Ensembl
PMID:10973942 PMID:11439185 PMID:12150907 PMID:12628165 PMID:12925569 PMID:16227987 PMID:18221368 PMID:19229105 PMID:19880420 PMID:20823226 PMID:21376232 PMID:23685073 PMID:23858059 PMID:25621951 PMID:32047033 More...
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 Reactome:R-HSA-5689111
NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775
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PRPF19
pre-mRNA processing factor 19
enables
IMP IEA IDA
(PMID:20595234) (PMID:11435423)
UniProt InterPro MGI
PMID:11435423 PMID:20595234
GO_REF:0000002 GO_REF:0000104
NCBI chr11:60,890,547...60,906,585
Ensembl chr11:60,890,547...60,906,585
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RABGEF1
RAB guanine nucleotide exchange factor 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 7:66,654,567...66,811,464
Ensembl chr 7:66,682,164...66,811,464
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RAD18
RAD18 E3 ubiquitin protein ligase
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 3:8,877,075...8,963,472
Ensembl chr 3:8,775,402...8,963,773
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RAG1
recombination activating 1
enables
IEA IBA
UniProt GO_Central TreeGrafter InterPro Ensembl
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118
NCBI chr11:36,510,353...36,579,762
Ensembl chr11:36,510,372...36,593,156
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RAG2
recombination activating 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr11:36,590,996...36,598,236
Ensembl chr11:36,575,574...36,598,279
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RBBP6
RB binding protein 6, ubiquitin ligase
enables
IMP IBA
(PMID:24726359)
UniProt GO_Central
PMID:24726359
GO_REF:0000033
NCBI chr16:24,539,566...24,572,863
Ensembl chr16:24,537,693...24,572,863
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RBX1
ring-box 1
enables
TAS IBA IDA
(PMID:10230407), (PMID:11027288), (PMID:16482215), (PMID:17636018), (PMID:20870715), (PMID:22017875), (PMID:22017876), (PMID:22405651), (PMID:23453970), (PMID:27626656), (PMID:29779948), (PMID:36608670)
Reactome GO_Central UniProt
PMID:10230407 PMID:11027288 PMID:16482215 PMID:17636018 PMID:20870715 PMID:22017875 PMID:22017876 PMID:22405651 PMID:23453970 PMID:27626656 PMID:29779948 PMID:36608670 More...
GO_REF:0000033 Reactome:R-HSA-1504190 Reactome:R-HSA-5635856 Reactome:R-HSA-5658424 Reactome:R-HSA-9755505 Reactome:R-HSA-9759172 Reactome:R-HSA-9762091 Reactome:R-HSA-9766645
NCBI chr22:40,951,378...40,973,309
Ensembl chr22:40,951,347...40,973,309
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RC3H1
ring finger and CCCH-type domains 1
enables
TAS IBA IEA
(PMID:19217324)
BHF-UCL GO_Central TreeGrafter
PMID:19217324
GO_REF:0000033 GO_REF:0000118
NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357
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RC3H2
ring finger and CCCH-type domains 2
enables
IDA IBA
(PMID:24448648), (PMID:26489670)
UniProt GO_Central
PMID:24448648 PMID:26489670
GO_REF:0000033
NCBI chr 9:122,844,556...122,905,359
Ensembl chr 9:122,844,556...122,905,359
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RCHY1
ring finger and CHY zinc finger domain containing 1
NOT|enables
IDA IBA
(PMID:20452352) (PMID:19483087), (PMID:33909987)
UniProt GO_Central
PMID:19483087 PMID:20452352 PMID:33909987
GO_REF:0000033
NCBI chr 4:75,479,033...75,514,715
Ensembl chr 4:75,479,033...75,514,764
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RFFL
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
enables
TAS IBA IDA
(PMID:17121812), (PMID:22609986)
Reactome GO_Central UniProt
PMID:17121812 PMID:22609986
GO_REF:0000033 Reactome:R-HSA-6804441
NCBI chr17:35,005,990...35,089,226
Ensembl chr17:35,005,990...35,089,319
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RFPL1
ret finger protein like 1
enables
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr22:29,387,909...29,442,455
Ensembl chr22:29,438,583...29,442,455
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RFPL2
ret finger protein like 2
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr22:32,190,438...32,205,073
Ensembl chr22:32,190,435...32,205,073
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RFPL3
ret finger protein like 3
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr22:32,354,885...32,361,161
Ensembl chr22:32,354,885...32,361,161
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RFPL4A
ret finger protein like 4A
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr19:55,757,294...55,763,421
Ensembl chr19:55,759,097...55,763,421
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RFPL4AL1
ret finger protein like 4A like 1
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr19:55,769,118...55,773,420
Ensembl chr19:55,769,118...55,773,420
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RFPL4B
ret finger protein like 4B
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 6:112,347,330...112,351,294
Ensembl chr 6:112,347,330...112,351,294
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RFWD3
ring finger and WD repeat domain 3
enables
IDA IBA
(PMID:20173098), (PMID:26474068), (PMID:28575657), (PMID:28575658)
UniProt GO_Central
PMID:20173098 PMID:26474068 PMID:28575657 PMID:28575658
GO_REF:0000033
NCBI chr16:74,621,399...74,666,877
Ensembl chr16:74,621,399...74,666,877
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RING1
ring finger protein 1
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 6:33,208,500...33,212,716
Ensembl chr 6:33,208,500...33,212,722
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RLIM
ring finger protein, LIM domain interacting
enables
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr X:74,582,976...74,614,624
Ensembl chr X:74,582,976...74,614,624
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RMND5A
required for meiotic nuclear division 5 homolog A
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 2:86,720,291...86,778,041
Ensembl chr 2:86,720,291...86,778,041
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RMND5B
required for meiotic nuclear division 5 homolog B
enables
IEA
InterPro
GO_REF:0000002
NCBI chr 5:178,131,014...178,150,568
Ensembl chr 5:178,130,996...178,150,568
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RNF10
ring finger protein 10
enables
IDA
(PMID:24105792), (PMID:34348161), (PMID:34469731)
UniProt
PMID:24105792 PMID:34348161 PMID:34469731
NCBI chr12:120,534,356...120,577,588
Ensembl chr12:120,533,480...120,577,588
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RNF103
ring finger protein 103
enables
TAS
Reactome
Reactome:R-HSA-8867288
NCBI chr 2:86,603,393...86,623,877
Ensembl chr 2:86,603,398...86,623,866
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RNF11
ring finger protein 11
enables
IDA IBA
(PMID:24105792)
FlyBase GO_Central
PMID:24105792
GO_REF:0000033
NCBI chr 1:51,236,273...51,273,447
Ensembl chr 1:51,236,273...51,273,447
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RNF111
ring finger protein 111
enables
TAS IBA IMP IEA
(PMID:16601693)
Reactome GO_Central BHF-UCL Ensembl
PMID:16601693
GO_REF:0000033 GO_REF:0000107 Reactome:R-HSA-6790487
NCBI chr15:58,987,663...59,097,419
Ensembl chr15:58,865,175...59,097,419
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RNF112
ring finger protein 112
enables
ISS IEA
UniProt Ensembl
GO_REF:0000024 GO_REF:0000107
NCBI chr17:19,411,232...19,417,276
Ensembl chr17:19,411,125...19,417,276
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RNF113A
ring finger protein 113A
enables
IMP
(PMID:28978524)
UniProt
PMID:28978524
NCBI chr X:119,870,475...119,871,733
Ensembl chr X:119,870,475...119,871,733
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RNF114
ring finger protein 114
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr20:49,936,397...49,953,885
Ensembl chr20:49,936,336...49,953,885
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RNF115
ring finger protein 115
enables
ISS IBA IDA IEA
(PMID:35343654)
UniProt GO_Central Ensembl
PMID:35343654
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr 1:145,738,868...145,824,095
Ensembl chr 1:145,738,868...145,824,095
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RNF121
ring finger protein 121
enables
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr11:71,929,046...71,997,597
Ensembl chr11:71,929,018...71,997,597
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RNF122
ring finger protein 122
enables
IMP
(PMID:20553626)
UniProt
PMID:20553626
NCBI chr 8:33,547,754...33,567,128
Ensembl chr 8:33,547,754...33,567,128
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RNF123
ring finger protein 123
enables
IDA
(PMID:15531880), (PMID:16227581), (PMID:25860612)
UniProt
PMID:15531880 PMID:16227581 PMID:25860612
NCBI chr 3:49,689,557...49,721,529
Ensembl chr 3:49,689,538...49,721,529
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RNF125
ring finger protein 125
enables
IDA IBA
(PMID:17460044), (PMID:25591766), (PMID:27411375)
UniProt GO_Central
PMID:17460044 PMID:25591766 PMID:27411375
GO_REF:0000033
NCBI chr18:32,018,825...32,088,144
Ensembl chr18:32,018,825...32,073,219
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RNF126
ring finger protein 126
enables
IEA IDA IBA
(PMID:23026136), (PMID:24981174), (PMID:36563124)
Ensembl UniProt TreeGrafter GO_Central InterPro
PMID:23026136 PMID:24981174 PMID:36563124
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr19:647,526...663,214
Ensembl chr19:647,526...663,233
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RNF128
ring finger protein 128
enables
IEA IBA TAS
(PMID:25635054)
Ensembl GO_Central BHF-UCL
PMID:25635054
GO_REF:0000033 GO_REF:0000107
NCBI chr X:106,693,838...106,797,016
Ensembl chr X:106,693,794...106,797,016
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RNF13
ring finger protein 13
enables
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr 3:149,812,688...149,962,139
Ensembl chr 3:149,812,770...149,962,139
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RNF130
ring finger protein 130
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 5:179,911,651...180,071,759
Ensembl chr 5:179,911,651...180,072,113
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RNF133
ring finger protein 133
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 7:122,697,735...122,699,117
Ensembl chr 7:122,697,735...122,699,117
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RNF135
ring finger protein 135
enables
IDA
(PMID:31006531)
UniProt
PMID:31006531
NCBI chr17:30,958,921...30,999,911
Ensembl chr17:30,970,984...30,999,911
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RNF138
ring finger protein 138
enables
IMP IEA IBA
(PMID:26502055), (PMID:26502057)
UniProt TreeGrafter GO_Central
PMID:26502055 PMID:26502057
GO_REF:0000033 GO_REF:0000118
NCBI chr18:32,091,874...32,131,561
Ensembl chr18:32,091,874...32,131,561
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RNF139
ring finger protein 139
enables
TAS IBA IDA
(PMID:10500182)
Reactome GO_Central UniProt
PMID:10500182
GO_REF:0000033 Reactome:R-HSA-8867288
NCBI chr 8:124,474,880...124,488,618
Ensembl chr 8:124,474,880...124,488,618
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RNF14
ring finger protein 14
enables
IEA IBA IDA
(PMID:27863242), (PMID:36638793), (PMID:37651229), (PMID:37951215), (PMID:37951216)
UniProt TreeGrafter GO_Central
PMID:27863242 PMID:36638793 PMID:37651229 PMID:37951215 PMID:37951216
GO_REF:0000033 GO_REF:0000117 GO_REF:0000118
NCBI chr 5:141,949,337...141,990,292
Ensembl chr 5:141,958,328...141,990,292
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RNF144A
ring finger protein 144A
enables
EXP IBA IDA
(PMID:24979766) (PMID:37955227)
Reactome GO_Central UniProt
PMID:24979766 PMID:37955227
GO_REF:0000033
NCBI chr 2:6,917,412...7,076,367
Ensembl chr 2:6,917,412...7,068,286
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RNF144B
ring finger protein 144B
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 6:18,387,350...18,468,870
Ensembl chr 6:18,387,350...18,468,870
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RNF145
ring finger protein 145
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 5:159,157,409...159,210,053
Ensembl chr 5:159,157,409...159,210,053
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RNF146
ring finger protein 146
enables
IEA TAS
InterPro Reactome
GO_REF:0000002 Reactome:R-HSA-3640861 Reactome:R-HSA-8948832
NCBI chr 6:127,266,682...127,288,562
Ensembl chr 6:127,266,726...127,288,567
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RNF148
ring finger protein 148
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 7:122,701,668...122,702,922
Ensembl chr 7:122,701,668...122,702,922
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RNF149
ring finger protein 149
enables
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr 2:101,271,219...101,308,701
Ensembl chr 2:101,271,219...101,308,701
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RNF150
ring finger protein 150
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 4:140,859,807...141,212,900
Ensembl chr 4:140,859,807...141,212,877
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RNF151
ring finger protein 151
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr16:1,966,856...1,968,949
Ensembl chr16:1,966,823...1,968,975
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RNF152
ring finger protein 152
enables
EXP IBA IDA IEA IMP
(PMID:25936802) (PMID:30514904)
Reactome GO_Central UniProt InterPro
PMID:25936802 PMID:30514904
GO_REF:0000002 GO_REF:0000033
NCBI chr18:61,808,067...61,894,412
Ensembl chr18:61,808,067...61,894,247
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RNF157
ring finger protein 157
enables
ISS IEA IBA
UniProt TreeGrafter GO_Central InterPro
GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118
NCBI chr17:76,142,474...76,240,493
Ensembl chr17:76,142,465...76,240,493
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RNF166
ring finger protein 166
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr16:88,696,501...88,706,408
Ensembl chr16:88,696,499...88,706,408
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RNF167
ring finger protein 167
enables
IDA IBA
(PMID:23129617), (PMID:23353890), (PMID:27808481), (PMID:33594058), (PMID:35114100)
UniProt GO_Central
PMID:23129617 PMID:23353890 PMID:27808481 PMID:33594058 PMID:35114100
GO_REF:0000033
NCBI chr17:4,940,092...4,945,222
Ensembl chr17:4,940,008...4,945,222
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RNF170
ring finger protein 170
enables
IEA IDA
(PMID:31076723)
InterPro UniProt
PMID:31076723
GO_REF:0000002
NCBI chr 8:42,849,637...42,897,299
Ensembl chr 8:42,849,637...42,897,290
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RNF175
ring finger protein 175
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 4:153,710,160...153,760,024
Ensembl chr 4:153,710,160...153,760,024
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RNF180
ring finger protein 180
enables
IEA IBA
InterPro GO_Central Ensembl
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107
NCBI chr 5:64,165,351...64,372,869
Ensembl chr 5:64,165,843...64,372,869
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RNF181
ring finger protein 181
enables
EXP IBA IDA
(PMID:26711259) (PMID:24811749)
Reactome GO_Central UniProt
PMID:24811749 PMID:26711259
GO_REF:0000033
NCBI chr 2:85,595,745...85,597,708
Ensembl chr 2:85,595,725...85,597,708
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RNF183
ring finger protein 183
enables
IDA IBA IEA IMP
(PMID:26567849) (PMID:29507230)
UniProt GO_Central Ensembl
PMID:26567849 PMID:29507230
GO_REF:0000033 GO_REF:0000107
NCBI chr 9:113,297,093...113,303,376
Ensembl chr 9:113,297,093...113,303,376
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RNF185
ring finger protein 185
enables
TAS IBA IEA IDA
(PMID:24019521), (PMID:27485036), (PMID:28273161)
Reactome GO_Central InterPro UniProt
PMID:24019521 PMID:27485036 PMID:28273161
GO_REF:0000002 GO_REF:0000033 Reactome:R-HSA-8866546 Reactome:R-HSA-8867288
NCBI chr22:31,160,182...31,207,019
Ensembl chr22:31,160,182...31,207,019
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RNF186
ring finger protein 186
enables
IDA IBA
(PMID:33280498)
UniProt GO_Central
PMID:33280498
GO_REF:0000033
NCBI chr 1:19,814,029...19,815,283
Ensembl chr 1:19,814,029...19,815,283
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RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 8:100,257,067...100,336,204
Ensembl chr 8:100,257,060...100,336,218
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RNF19B
ring finger protein 19B
enables
IDA IBA
(PMID:27485036)
UniProt GO_Central
PMID:27485036
GO_REF:0000033
NCBI chr 1:32,929,036...32,964,809
Ensembl chr 1:32,936,445...32,964,809
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RNF2
ring finger protein 2
enables
ISS IBA IEA
UniProt GO_Central Ensembl
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr 1:185,045,558...185,102,603
Ensembl chr 1:185,045,497...185,102,603
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RNF20
ring finger protein 20
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 9:101,533,853...101,563,344
Ensembl chr 9:101,533,853...101,563,344
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RNF208
ring finger protein 208
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 9:137,220,259...137,223,408
Ensembl chr 9:137,220,247...137,222,240
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RNF213
ring finger protein 213
enables
IDA
(PMID:32139119), (PMID:33842849)
UniProt
PMID:32139119 PMID:33842849
NCBI chr17:80,260,852...80,398,794
Ensembl chr17:80,260,852...80,398,794
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RNF215
ring finger protein 215
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr22:30,378,821...30,387,411
Ensembl chr22:30,368,811...30,421,771
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RNF216
ring finger protein 216
enables
EXP
(PMID:19893624)
Reactome
PMID:19893624
NCBI chr 7:5,620,047...5,781,663
Ensembl chr 7:5,620,047...5,781,696
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RNF217
ring finger protein 217
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 6:124,962,437...125,092,634
Ensembl chr 6:124,962,437...125,092,633
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RNF220
ring finger protein 220
enables
IEA IBA
Ensembl GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr 1:44,404,783...44,651,724
Ensembl chr 1:44,405,194...44,651,723
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RNF223
ring finger protein 223
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 1:1,070,967...1,074,306
Ensembl chr 1:1,070,967...1,074,306
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RNF225
ring finger protein 225
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr19:58,395,656...58,397,079
Ensembl chr19:58,395,656...58,397,079
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RNF227
ring finger protein 227
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr17:7,913,324...7,916,318
Ensembl chr17:7,913,339...7,916,289
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RNF228
ring finger protein 228
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 2:222,314,148...222,320,155
Ensembl chr 2:222,317,242...222,320,208
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RNF25
ring finger protein 25
enables
IEA IDA IBA
(PMID:26475854), (PMID:27863242), (PMID:36638793), (PMID:37651229), (PMID:37951215)
InterPro UniProt GO_Central Ensembl
PMID:26475854 PMID:27863242 PMID:36638793 PMID:37651229 PMID:37951215
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117
NCBI chr 2:218,663,892...218,672,002
Ensembl chr 2:218,663,892...218,672,002
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RNF26
ring finger protein 26
enables
IDA IEA IBA
(PMID:25254379), (PMID:27368102), (PMID:33472082)
UniProt TreeGrafter GO_Central
PMID:25254379 PMID:27368102 PMID:33472082
GO_REF:0000033 GO_REF:0000118
NCBI chr11:119,334,527...119,337,309
Ensembl chr11:119,334,527...119,337,309
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RNF31
ring finger protein 31
enables
IDA IBA IEA
(PMID:28481331)
UniProt GO_Central Ensembl
PMID:28481331
GO_REF:0000033 GO_REF:0000107
NCBI chr14:24,146,875...24,160,655
Ensembl chr14:24,146,683...24,160,660
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RNF34
ring finger protein 34
enables
IDA IBA TAS IMP
(PMID:15069192), (PMID:17121812) (PMID:22064484)
UniProt GO_Central Reactome
PMID:15069192 PMID:17121812 PMID:22064484
GO_REF:0000033 Reactome:R-HSA-6804441
NCBI chr12:121,400,118...121,424,348
Ensembl chr12:121,400,083...121,430,623
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RNF38
ring finger protein 38
enables
IDA IBA
(PMID:23973461)
FlyBase GO_Central
PMID:23973461
GO_REF:0000033
NCBI chr 9:36,336,400...36,487,669
Ensembl chr 9:36,336,396...36,487,548
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RNF39
ring finger protein 39
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 6:30,070,270...30,075,769
Ensembl chr 6:30,070,266...30,075,849
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RNF4
ring finger protein 4
enables
ISO IDA
(PMID:35013556)
RGD UniProt
PMID:21857666 PMID:35013556
RGD:9831417
NCBI chr 4:2,469,106...2,515,857
Ensembl chr 4:2,462,220...2,515,857
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RNF40
ring finger protein 40
enables
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr16:30,761,612...30,776,307
Ensembl chr16:30,761,745...30,776,307
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RNF41
ring finger protein 41
enables
IDA IBA IEA
(PMID:18541373)
ParkinsonsUK-UCL GO_Central InterPro
PMID:18541373
GO_REF:0000002 GO_REF:0000033
NCBI chr12:56,202,179...56,221,969
Ensembl chr12:56,202,179...56,221,933
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RNF43
ring finger protein 43
enables
TAS IBA
(PMID:24431302)
ParkinsonsUK-UCL GO_Central
PMID:24431302
GO_REF:0000033
NCBI chr17:58,352,500...58,417,534
Ensembl chr17:58,353,676...58,417,595
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RNF44
ring finger protein 44
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 5:176,526,712...176,543,513
Ensembl chr 5:176,526,712...176,538,025
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RNF5
ring finger protein 5
enables
TAS IEA IBA
(PMID:24019521)
Reactome TreeGrafter GO_Central UniProt InterPro
PMID:24019521
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 Reactome:R-HSA-8866546 Reactome:R-HSA-8867288
NCBI chr 6:32,178,405...32,180,793
Ensembl chr 6:32,178,405...32,180,793
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RNF6
ring finger protein 6
enables
IEA IBA ISS
Ensembl TreeGrafter GO_Central UniProt
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr13:26,132,115...26,223,085
Ensembl chr13:26,132,115...26,222,314
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RNF7
ring finger protein 7
enables
IEA IBA
InterPro TreeGrafter GO_Central
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr 3:141,738,298...141,747,560
Ensembl chr 3:141,738,249...141,747,560
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RNF8
ring finger protein 8
enables
IEA IBA IDA
(PMID:18001824), (PMID:18001825), (PMID:18948756), (PMID:21911360), (PMID:22266820), (PMID:22373579), (PMID:22980979), (PMID:23115235)
Ensembl GO_Central UniProt
PMID:18001824 PMID:18001825 PMID:18948756 PMID:21911360 PMID:22266820 PMID:22373579 PMID:22980979 PMID:23115235 More...
GO_REF:0000033 GO_REF:0000107
NCBI chr 6:37,353,983...37,394,734
Ensembl chr 6:37,353,979...37,394,734
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RNFT1
ring finger protein, transmembrane 1
enables
IDA IBA IEA
(PMID:27485036)
UniProt GO_Central InterPro
PMID:27485036
GO_REF:0000002 GO_REF:0000033
NCBI chr17:59,952,240...59,964,740
Ensembl chr17:59,952,240...59,964,761
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RNFT2
ring finger protein, transmembrane 2
enables
IEA IBA
InterPro GO_Central
GO_REF:0000002 GO_REF:0000033
NCBI chr12:116,738,315...116,853,631
Ensembl chr12:116,738,178...116,853,631
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RPGR
retinitis pigmentosa GTPase regulator
enables
IBA IEA
GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118
NCBI chr X:38,269,163...38,327,509
Ensembl chr X:38,269,163...38,327,544
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SERGEF
secretion regulating guanine nucleotide exchange factor
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr11:17,788,048...18,013,047
Ensembl chr11:17,788,048...18,013,047
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SH3RF1
SH3 domain containing ring finger 1
enables
IMP IBA
(PMID:20696164)
UniProt GO_Central
PMID:20696164
GO_REF:0000033
NCBI chr 4:169,094,259...169,270,956
Ensembl chr 4:169,094,259...169,270,956
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SH3RF2
SH3 domain containing ring finger 2
enables
IMP IBA IEA
(PMID:24130170)
UniProt GO_Central TreeGrafter
PMID:24130170
GO_REF:0000033 GO_REF:0000118
NCBI chr 5:145,936,578...146,081,773
Ensembl chr 5:145,936,578...146,081,791
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SH3RF3
SH3 domain containing ring finger 3
enables
IMP IBA
(PMID:20696164)
UniProt GO_Central
PMID:20696164
GO_REF:0000033
NCBI chr 2:109,129,205...109,504,634
Ensembl chr 2:109,129,205...109,504,634
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SHPRH
SNF2 histone linker PHD RING helicase
enables
EXP IBA IEA
(PMID:17108083), (PMID:17130289), (PMID:18719106)
Reactome GO_Central TreeGrafter
PMID:17108083 PMID:17130289 PMID:18719106
GO_REF:0000033 GO_REF:0000118
NCBI chr 6:145,857,838...145,964,358
Ensembl chr 6:145,864,245...145,964,423
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SIAH1
siah E3 ubiquitin protein ligase 1
enables
IDA IBA IEA IMP
(PMID:23001567) (PMID:28546513)
MGI GO_Central TreeGrafter UniProt
PMID:23001567 PMID:28546513
GO_REF:0000033 GO_REF:0000118
NCBI chr16:48,360,531...48,387,246
Ensembl chr16:48,356,364...48,448,402
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SIAH2
siah E3 ubiquitin protein ligase 2
enables
ISS IEA IBA
UniProt TreeGrafter GO_Central Ensembl
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr 3:150,741,125...150,763,169
Ensembl chr 3:150,741,125...150,763,477
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SIAH3
siah E3 ubiquitin protein ligase family member 3
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr13:45,777,242...45,851,753
Ensembl chr13:45,777,242...45,851,753
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SMURF1
SMAD specific E3 ubiquitin protein ligase 1
enables
IDA IBA TAS IEA
(PMID:11278251), (PMID:12151385)
BHF-UCL GO_Central Reactome InterPro
PMID:11278251 PMID:12151385
GO_REF:0000002 GO_REF:0000033 Reactome:R-HSA-201445 Reactome:R-HSA-4608852 Reactome:R-HSA-8952419
NCBI chr 7:99,027,440...99,144,108
Ensembl chr 7:99,027,440...99,144,108
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SMURF2
SMAD specific E3 ubiquitin protein ligase 2
enables
TAS IEA IBA IDA
(PMID:19122240)
Reactome TreeGrafter GO_Central BHF-UCL InterPro
PMID:19122240
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-201445 Reactome:R-HSA-4608852 Reactome:R-HSA-4641129 Reactome:R-HSA-8952419
NCBI chr17:64,542,282...64,662,307
Ensembl chr17:64,542,282...64,662,307
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STUB1
STIP1 homology and U-box containing protein 1
enables
IGI IBA IDA IMP IEA TAS
(PMID:16207813) (PMID:14610072), (PMID:16275660), (PMID:16809764), (PMID:19103148), (PMID:24043303), (PMID:24613385), (PMID:26265139) (PMID:15781469), (PMID:16809764), (PMID:23990462)
ARUK-UCL GO_Central ParkinsonsUK-UCL HGNC-UCL Ensembl Reactome
PMID:14610072 PMID:15781469 PMID:16207813 PMID:16275660 PMID:16809764 PMID:19103148 PMID:23990462 PMID:24043303 PMID:24613385 PMID:26265139 More...
GO_REF:0000033 GO_REF:0000107 Reactome:R-HSA-6807134 Reactome:R-HSA-9009308
NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870
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SYVN1
synoviolin 1
enables
NAS IBA IMP IDA TAS
(PMID:22590560) (PMID:21245296), (PMID:28842558) (PMID:12459480), (PMID:14593114), (PMID:17059562), (PMID:19103148) (PMID:21062743), (PMID:23710284)
ParkinsonsUK-UCL GO_Central MGI
PMID:12459480 PMID:14593114 PMID:17059562 PMID:19103148 PMID:21062743 PMID:21245296 PMID:22590560 PMID:23710284 PMID:28842558 More...
GO_REF:0000033 Reactome:R-HSA-8867288
NCBI chr11:65,127,279...65,134,519
Ensembl chr11:65,121,780...65,134,532
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TMEM129
transmembrane protein 129, E3 ubiquitin ligase
enables
IEA IBA IDA EXP
(PMID:24807418) (PMID:24807418), (PMID:25030448)
InterPro GO_Central ParkinsonsUK-UCL Reactome
PMID:24807418 PMID:25030448
GO_REF:0000002 GO_REF:0000033
NCBI chr 4:1,715,952...1,721,323
Ensembl chr 4:1,715,952...1,721,358
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TOPORS
TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
enables
IDA IEA IBA
(PMID:15247280)
BHF-UCL TreeGrafter GO_Central
PMID:15247280
GO_REF:0000033 GO_REF:0000118
NCBI chr 9:32,540,544...32,552,586
Ensembl chr 9:32,540,544...32,552,586
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TRAF3
TNF receptor associated factor 3
enables
IDA
(PMID:19898473)
UniProt
PMID:19898473
NCBI chr14:102,777,449...102,911,500
Ensembl chr14:102,777,449...102,911,500
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TRAF3IP2
TRAF3 interacting protein 2
enables
IEA IDA
(PMID:19825828)
Ensembl UniProt
PMID:19825828
GO_REF:0000107
NCBI chr 6:111,555,381...111,605,878
Ensembl chr 6:111,555,381...111,606,906
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TRAF6
TNF receptor associated factor 6
enables
IEA IBA IDA
(PMID:15125833), (PMID:15465037), (PMID:17135271), (PMID:18758450), (PMID:19675569), (PMID:19713527), (PMID:23015697), (PMID:23514740), (PMID:23524951), (PMID:26839314), (PMID:30927622), (PMID:33799071)
Ensembl GO_Central UniProt
PMID:15125833 PMID:15465037 PMID:17135271 PMID:18758450 PMID:19675569 PMID:19713527 PMID:23015697 PMID:23514740 PMID:23524951 PMID:26839314 PMID:30927622 PMID:33799071 More...
GO_REF:0000033 GO_REF:0000107
NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272
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TRAF7
TNF receptor associated factor 7
enables
IDA
(PMID:21518757)
UniProt
PMID:21518757
NCBI chr16:2,155,782...2,178,129
Ensembl chr16:2,155,698...2,178,129
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TRAIP
TRAF interacting protein
enables
IEA IBA
Ensembl GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr 3:49,828,601...49,856,564
Ensembl chr 3:49,828,601...49,856,574
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TRIM10
tripartite motif containing 10
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 6:30,151,943...30,164,009
Ensembl chr 6:30,151,943...30,161,211
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TRIM11
tripartite motif containing 11
enables
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr 1:228,393,676...228,406,835
Ensembl chr 1:228,393,673...228,406,835
G
TRIM13
tripartite motif containing 13
enables
TAS IBA IEA
Reactome GO_Central TreeGrafter
GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-8867288
NCBI chr13:49,997,042...50,018,467
Ensembl chr13:49,995,888...50,020,481
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TRIM14
tripartite motif containing 14
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 9:98,035,797...98,119,222
Ensembl chr 9:98,069,275...98,119,222
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TRIM15
tripartite motif containing 15
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 6:30,163,546...30,172,693
Ensembl chr 6:30,163,206...30,172,693
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TRIM17
tripartite motif containing 17
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 1:228,407,935...228,416,861
Ensembl chr 1:228,407,935...228,416,861
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TRIM2
tripartite motif containing 2
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 4:153,152,163...153,339,317
Ensembl chr 4:153,152,163...153,339,319
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TRIM21
tripartite motif containing 21
enables
TAS IBA IDA
(PMID:26342464), (PMID:36359729), (PMID:36426955), (PMID:36692217), (PMID:36943869), (PMID:37816088)
Reactome GO_Central UniProt
PMID:26342464 PMID:36359729 PMID:36426955 PMID:36692217 PMID:36943869 PMID:37816088 More...
GO_REF:0000033 Reactome:R-HSA-9759154
NCBI chr11:4,384,897...4,393,702
Ensembl chr11:4,384,897...4,393,702
G
TRIM22
tripartite motif containing 22
enables
IDA IBA IEA
(PMID:36159777)
UniProt GO_Central TreeGrafter
PMID:36159777
GO_REF:0000033 GO_REF:0000118
NCBI chr11:5,689,790...5,710,863
Ensembl chr11:5,689,610...5,737,089
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TRIM23
tripartite motif containing 23
enables
IDA
(PMID:28871090)
UniProt
PMID:28871090
NCBI chr 5:65,589,690...65,624,333
Ensembl chr 5:65,589,690...65,625,975
G
TRIM24
tripartite motif containing 24
enables
IDA IEA
(PMID:19556538)
UniProt Ensembl
PMID:19556538
GO_REF:0000107
NCBI chr 7:138,460,259...138,589,996
Ensembl chr 7:138,460,259...138,589,996
G
TRIM25
tripartite motif containing 25
enables
IMP IDA
(PMID:24810856) (PMID:16352599), (PMID:17392790), (PMID:31953436)
ParkinsonsUK-UCL UniProt
PMID:16352599 PMID:17392790 PMID:24810856 PMID:31953436
NCBI chr17:56,887,909...56,914,049
Ensembl chr17:56,836,387...56,914,080
G
TRIM26
tripartite motif containing 26
enables
IDA IBA IEA
(PMID:29203640), (PMID:34017102)
UniProt GO_Central TreeGrafter
PMID:29203640 PMID:34017102
GO_REF:0000033 GO_REF:0000118
NCBI chr 6:30,184,455...30,213,406
Ensembl chr 6:30,184,455...30,213,427
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TRIM27
tripartite motif containing 27
enables
EXP IBA IEA IDA
(PMID:23419514) (PMID:22829933), (PMID:26358190), (PMID:35670107)
Reactome GO_Central TreeGrafter UniProt
PMID:22829933 PMID:23419514 PMID:26358190 PMID:35670107
GO_REF:0000033 GO_REF:0000118
NCBI chr 6:28,903,002...28,923,985
Ensembl chr 6:28,903,002...28,923,988
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TRIM28
tripartite motif containing 28
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr19:58,544,064...58,550,715
Ensembl chr19:58,544,064...58,550,722
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TRIM3
tripartite motif containing 3
enables
IEA IBA IDA
(PMID:32878999)
Ensembl TreeGrafter GO_Central UniProt
PMID:32878999
GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr11:6,448,613...6,474,459
Ensembl chr11:6,448,613...6,474,459
G
TRIM31
tripartite motif containing 31
enables
IDA IBA IEA
(PMID:27929086), (PMID:27992402)
UniProt GO_Central TreeGrafter
PMID:27929086 PMID:27992402
GO_REF:0000033 GO_REF:0000118
NCBI chr 6:30,102,897...30,113,090
Ensembl chr 6:30,102,897...30,113,090
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TRIM32
tripartite motif containing 32
enables
IEA IBA IMP IDA
(PMID:37943659) (PMID:16816390), (PMID:28498859), (PMID:31123703)
Ensembl GO_Central UniProt BHF-UCL
PMID:16816390 PMID:28498859 PMID:31123703 PMID:37943659
GO_REF:0000033 GO_REF:0000107
NCBI chr 9:116,687,305...116,701,299
Ensembl chr 9:116,687,305...116,701,300
G
TRIM33
tripartite motif containing 33
enables
ISO
(PMID:26624618)
MGI
PMID:26624618
NCBI chr 1:114,392,790...114,511,203
Ensembl chr 1:114,392,790...114,511,203
G
TRIM34
tripartite motif containing 34
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr11:5,619,944...5,644,398
Ensembl chr11:5,619,764...5,644,398
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TRIM35
tripartite motif containing 35
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 8:27,284,886...27,311,272
Ensembl chr 8:27,284,886...27,311,272
G
TRIM37
tripartite motif containing 37
enables
IDA IBA
(PMID:28724525)
UniProt GO_Central
PMID:28724525
GO_REF:0000033
NCBI chr17:58,967,201...59,106,880
Ensembl chr17:58,982,638...59,106,921
G
TRIM38
tripartite motif containing 38
enables
ISS IBA IEA
UniProt GO_Central Ensembl
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr 6:25,962,802...25,991,231
Ensembl chr 6:25,962,802...25,991,231
G
TRIM39
tripartite motif containing 39
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 6:30,326,469...30,343,729
Ensembl chr 6:30,326,479...30,343,729
G
TRIM39-RPP21
TRIM39-RPP21 readthrough
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr 6:30,329,311...30,346,858
Ensembl chr 6:30,328,907...30,346,854
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TRIM4
tripartite motif containing 4
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 7:99,890,403...99,919,530
Ensembl chr 7:99,876,958...99,919,531
G
TRIM40
tripartite motif containing 40
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 6:30,136,140...30,148,735
Ensembl chr 6:30,136,124...30,148,735
G
TRIM41
tripartite motif containing 41
enables
IDA IBA IEA
(PMID:29760876)
UniProt GO_Central TreeGrafter
PMID:29760876
GO_REF:0000033 GO_REF:0000118
NCBI chr 5:181,223,281...181,235,808
Ensembl chr 5:181,222,499...181,235,808
G
TRIM43
tripartite motif containing 43
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 2:95,592,001...95,599,778
Ensembl chr 2:95,592,001...95,599,778
G
TRIM43B
tripartite motif containing 43B
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 2:95,477,008...95,484,754
Ensembl chr 2:95,477,008...95,484,754
G
TRIM44
tripartite motif containing 44
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr11:35,662,775...35,818,007
Ensembl chr11:35,662,775...35,818,007
G
TRIM45
tripartite motif containing 45
enables
IDA IBA
(PMID:28542145), (PMID:36681779)
FlyBase GO_Central
PMID:28542145 PMID:36681779
GO_REF:0000033
NCBI chr 1:117,111,060...117,123,927
Ensembl chr 1:117,111,060...117,122,587
G
TRIM47
tripartite motif containing 47
enables
IDA
(PMID:34110282)
UniProt
PMID:34110282
NCBI chr17:75,874,164...75,878,581
Ensembl chr17:75,874,164...75,878,581
G
TRIM48
tripartite motif containing 48
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr11:55,262,155...55,271,114
Ensembl chr11:55,262,155...55,271,114
G
TRIM49
tripartite motif containing 49
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr11:89,766,451...89,808,575
Ensembl chr11:89,797,655...89,808,575
G
TRIM49B
tripartite motif containing 49B
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr11:49,028,823...49,038,155
Ensembl chr11:49,027,501...49,038,451
G
TRIM49C
tripartite motif containing 49C
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr11:90,031,106...90,073,531
Ensembl chr11:90,031,106...90,042,025
G
TRIM49D1
tripartite motif containing 49D1
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr11:89,911,409...89,922,245
Ensembl chr11:89,911,111...89,922,245
G
TRIM49D2
tripartite motif containing 49D2
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr11:89,924,064...89,933,063
Ensembl chr11:89,924,064...89,933,063
G
TRIM5
tripartite motif containing 5
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr11:5,588,635...5,685,074
Ensembl chr11:5,663,195...5,938,619
G
TRIM50
tripartite motif containing 50
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 7:73,312,536...73,328,082
Ensembl chr 7:73,312,536...73,328,082
G
TRIM51
tripartite motif-containing 51
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr11:55,883,297...55,891,810
Ensembl chr11:55,883,297...55,891,810
G
TRIM51G
tripartite motif-containing 51G
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr11:48,975,498...48,983,885
Ensembl chr11:48,975,498...48,983,885
G
TRIM52
tripartite motif containing 52
enables
IDA
(PMID:27667714)
UniProt
PMID:27667714
NCBI chr 5:181,249,062...181,261,143
Ensembl chr 5:181,254,077...181,261,150
G
TRIM54
tripartite motif containing 54
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 2:27,282,429...27,307,435
Ensembl chr 2:27,282,429...27,307,439
G
TRIM55
tripartite motif containing 55
enables
IDA IBA
(PMID:37816088)
UniProt GO_Central
PMID:37816088
GO_REF:0000033
NCBI chr 8:66,113,351...66,175,485
Ensembl chr 8:66,126,896...66,175,485
G
TRIM56
tripartite motif containing 56
enables
ISS IBA IDA
(PMID:29426904), (PMID:35952808)
UniProt GO_Central
PMID:29426904 PMID:35952808
GO_REF:0000024 GO_REF:0000033
NCBI chr 7:101,085,481...101,097,967
Ensembl chr 7:101,085,481...101,097,967
G
TRIM58
tripartite motif containing 58
enables
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr 1:247,857,187...247,880,138
Ensembl chr 1:247,857,187...247,880,138
G
TRIM59
tripartite motif containing 59
enables
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr 3:160,435,503...160,449,786
Ensembl chr 3:160,432,445...160,485,773
G
TRIM6
tripartite motif containing 6
enables
IMP IBA IEA IDA
(PMID:24882218) (PMID:28679761), (PMID:35263596)
UniProt GO_Central TreeGrafter
PMID:24882218 PMID:28679761 PMID:35263596
GO_REF:0000033 GO_REF:0000118
NCBI chr11:5,596,111...5,612,952
Ensembl chr11:5,596,109...5,612,958
G
TRIM60
tripartite motif containing 60
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 4:165,031,999...165,041,749
Ensembl chr 4:165,016,458...165,041,749
G
TRIM61
tripartite motif containing 61
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 4:164,954,446...164,977,657
Ensembl chr 4:164,954,446...164,977,668
G
TRIM62
tripartite motif containing 62
enables
IBA IDA
(PMID:26488816)
GO_Central UniProt
PMID:26488816
GO_REF:0000033
NCBI chr 1:33,145,399...33,182,043
Ensembl chr 1:33,145,399...33,182,059
G
TRIM63
tripartite motif containing 63
enables
IDA IBA IEA
(PMID:34244144)
FlyBase GO_Central TreeGrafter
PMID:34244144
GO_REF:0000033 GO_REF:0000118
NCBI chr 1:26,051,301...26,067,630
Ensembl chr 1:26,051,301...26,068,436
G
TRIM64
tripartite motif containing 64
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr11:89,966,037...89,974,072
Ensembl chr11:89,966,037...89,974,072
G
TRIM64B
tripartite motif containing 64B
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr11:89,870,438...89,878,487
Ensembl chr11:89,870,438...89,878,487
G
TRIM64C
tripartite motif containing 64C
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr11:49,053,714...49,059,112
Ensembl chr11:49,053,714...49,059,112
G
TRIM65
tripartite motif containing 65
enables
IDA
(PMID:28594402), (PMID:31310649), (PMID:34512673)
UniProt
PMID:28594402 PMID:31310649 PMID:34512673
NCBI chr17:75,879,537...75,896,951
Ensembl chr17:75,880,335...75,896,951
G
TRIM68
tripartite motif containing 68
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr11:4,598,672...4,608,231
Ensembl chr11:4,598,672...4,608,231
G
TRIM69
tripartite motif containing 69
enables
IDA IBA
(PMID:37739411)
UniProt GO_Central
PMID:37739411
GO_REF:0000033
NCBI chr15:44,736,528...44,767,827
Ensembl chr15:44,728,988...44,767,829
G
TRIM7
tripartite motif containing 7
enables
IDA IBA IEA
(PMID:35893676)
UniProt GO_Central TreeGrafter
PMID:35893676
GO_REF:0000033 GO_REF:0000118
NCBI chr 5:181,193,924...181,205,196
Ensembl chr 5:181,193,924...181,205,293
G
TRIM71
tripartite motif containing 71
enables
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr 3:32,817,997...32,897,824
Ensembl chr 3:32,817,997...32,897,824
G
TRIM72
tripartite motif containing 72
enables
IEA IBA
Ensembl GO_Central
GO_REF:0000033 GO_REF:0000107
NCBI chr16:31,214,119...31,231,537
Ensembl chr16:31,214,119...31,231,537
G
TRIM73
tripartite motif containing 73
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 7:75,395,629...75,405,605
Ensembl chr 7:75,395,063...75,410,996
G
TRIM74
tripartite motif containing 74
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 7:72,954,868...72,969,681
Ensembl chr 7:72,959,485...72,969,466
G
TRIM75
tripartite motif containing 75
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 4:165,053,866...165,060,554
Ensembl chr 4:165,053,866...165,060,554
G
TRIM77
tripartite motif containing 77
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr11:89,710,299...89,717,872
Ensembl chr11:89,710,299...89,717,872
G
TRIM8
tripartite motif containing 8
enables
IDA
(PMID:27995356)
UniProt
PMID:27995356
NCBI chr10:102,644,479...102,658,319
Ensembl chr10:102,642,503...102,658,318
G
TRIM9
tripartite motif containing 9
enables
IDA
(PMID:20085810)
UniProt
PMID:20085810
NCBI chr14:50,975,266...51,095,105
Ensembl chr14:50,975,262...51,096,061
G
TRIML1
tripartite motif family like 1
enables
IBA
GO_Central
GO_REF:0000033
NCBI chr 4:188,137,229...188,150,767
Ensembl chr 4:188,139,441...188,147,743
G
TRIML2
tripartite motif family like 2
enables
IEA IBA
TreeGrafter GO_Central
GO_REF:0000033 GO_REF:0000118
NCBI chr 4:188,091,272...188,109,603
Ensembl chr 4:188,091,272...188,109,603
G
TRIP12
thyroid hormone receptor interactor 12
enables
IDA IBA IEA IMP
(PMID:18627766), (PMID:20208519), (PMID:30982744) (PMID:19028681)
UniProt GO_Central TreeGrafter InterPro
PMID:18627766 PMID:19028681 PMID:20208519 PMID:30982744
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118
NCBI chr 2:229,763,837...229,923,186
Ensembl chr 2:229,763,837...229,923,239
G
UBE2C
ubiquitin conjugating enzyme E2 C
enables
TAS
Reactome
Reactome:R-HSA-9686969
NCBI chr20:45,812,644...45,816,952
Ensembl chr20:45,812,576...45,816,957
G
UBE2D1
ubiquitin conjugating enzyme E2 D1
enables
IDA
(PMID:8530467)
GO_Central
PMID:8530467
NCBI chr10:58,335,006...58,370,748
Ensembl chr10:58,334,979...58,370,751
G
UBE2D2
ubiquitin conjugating enzyme E2 D2
enables
IDA
(PMID:8530467)
GO_Central
PMID:8530467
NCBI chr 5:139,526,240...139,628,434
Ensembl chr 5:139,526,431...139,628,434
G
UBE2D3
ubiquitin conjugating enzyme E2 D3
enables
IDA
(PMID:8530467)
GO_Central
PMID:8530467
NCBI chr 4:102,794,383...102,868,895
Ensembl chr 4:102,794,383...102,868,896
G
UBE2O
ubiquitin conjugating enzyme E2 O
enables
IDA
(PMID:23455153)
MGI
PMID:23455153
NCBI chr17:76,389,456...76,453,152
Ensembl chr17:76,389,456...76,453,152
G
UBE3A
ubiquitin protein ligase E3A
enables
IMP IBA IEA IDA
(PMID:7708685) (PMID:30020076)
CACAO GO_Central TreeGrafter UniProt InterPro Ensembl
PMID:7708685 PMID:30020076
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr15:25,333,728...25,439,056
Ensembl chr15:25,333,728...25,439,051
G
UBE3B
ubiquitin protein ligase E3B
enables
IEA IBA
InterPro TreeGrafter GO_Central
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr12:109,477,634...109,547,829
Ensembl chr12:109,477,402...109,536,705
G
UBE3C
ubiquitin protein ligase E3C
enables
IEA IBA IDA
(PMID:11278995), (PMID:21167755), (PMID:24811749), (PMID:25752573), (PMID:25752577), (PMID:32039437), (PMID:33637724)
InterPro TreeGrafter GO_Central UniProt
PMID:11278995 PMID:21167755 PMID:24811749 PMID:25752573 PMID:25752577 PMID:32039437 PMID:33637724 More...
GO_REF:0000002 GO_REF:0000033 GO_REF:0000118
NCBI chr 7:157,138,926...157,269,370
Ensembl chr 7:157,138,926...157,269,370
G
UBE3D
ubiquitin protein ligase E3D
enables
IDA IBA
(PMID:15749827)
UniProt GO_Central
PMID:15749827
GO_REF:0000033
NCBI chr 6:82,880,802...83,065,841
Ensembl chr 6:82,892,390...83,065,841
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UBE4A
ubiquitination factor E4A
enables
ISO
(PMID:11435423)
MGI
PMID:11435423
NCBI chr11:118,359,600...118,399,211
Ensembl chr11:118,359,600...118,399,211
G
UBE4B
ubiquitination factor E4B
enables
ISO
(PMID:11435423), (PMID:15466860), (PMID:20017557), (PMID:23509263)
MGI
PMID:11435423 PMID:15466860 PMID:20017557 PMID:23509263
NCBI chr 1:10,032,958...10,181,239
Ensembl chr 1:10,032,832...10,181,239
G
UBOX5
U-box domain containing 5
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr20:3,107,573...3,159,865
Ensembl chr20:3,107,573...3,160,196
G
UBR1
ubiquitin protein ligase E3 component n-recognin 1
enables
IEA IDA IBA
(PMID:15548684), (PMID:18162545)
InterPro UniProt GO_Central
PMID:15548684 PMID:18162545
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104
NCBI chr15:42,942,897...43,106,038
Ensembl chr15:42,942,897...43,106,113
G
UBR2
ubiquitin protein ligase E3 component n-recognin 2
enables
IEA IDA IBA
(PMID:15548684), (PMID:38225265)
UniProt GO_Central InterPro Ensembl
PMID:15548684 PMID:38225265
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107
NCBI chr 6:42,564,029...42,693,505
Ensembl chr 6:42,564,029...42,693,505
G
UBR3
ubiquitin protein ligase E3 component n-recognin 3
enables
IEA IBA
InterPro GO_Central Ensembl UniProt
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107
NCBI chr 2:169,827,454...170,084,131
Ensembl chr 2:169,827,454...170,084,131
G
UBR4
ubiquitin protein ligase E3 component n-recognin 4
enables
IDA
(PMID:23932781), (PMID:29033132), (PMID:34893540), (PMID:37891180), (PMID:38030679), (PMID:38182926), (PMID:38297121)
UniProt
PMID:23932781 PMID:29033132 PMID:34893540 PMID:37891180 PMID:38030679 PMID:38182926 PMID:38297121 More...
NCBI chr 1:19,074,510...19,210,266
Ensembl chr 1:19,074,510...19,210,266
G
UBR5
ubiquitin protein ligase E3 component n-recognin 5
enables
ISO IDA
(PMID:28689657), (PMID:29033132), (PMID:29378950), (PMID:33208877), (PMID:35217622), (PMID:37040767), (PMID:37409633), (PMID:37478846), (PMID:37478862), (PMID:37620400)
RGD UniProt
PMID:12239083 PMID:28689657 PMID:29033132 PMID:29378950 PMID:33208877 PMID:35217622 PMID:37040767 PMID:37409633 PMID:37478846 PMID:37478862 PMID:37620400 More...
RGD:625681
NCBI chr 8:102,252,273...102,412,700
Ensembl chr 8:102,252,273...102,412,759
G
UBR7
ubiquitin protein ligase E3 component n-recognin 7
enables
IEA
InterPro
GO_REF:0000002
NCBI chr14:93,207,256...93,229,215
Ensembl chr14:93,207,241...93,229,215
G
UHRF1
ubiquitin like with PHD and ring finger domains 1
enables
IEA IBA IDA ISS
(PMID:37728657)
Ensembl GO_Central UniProt BHF-UCL
PMID:37728657
GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107
NCBI chr19:4,903,080...4,962,154
Ensembl chr19:4,903,080...4,962,154
G
UHRF2
ubiquitin like with PHD and ring finger domains 2
enables
IDA IBA IEA
(PMID:14741369)
MGI GO_Central UniProt
PMID:14741369
GO_REF:0000033 GO_REF:0000104
NCBI chr 9:6,413,199...6,507,054
Ensembl chr 9:6,413,151...6,507,054
G
VPS11
VPS11 core subunit of CORVET and HOPS complexes
enables
IMP
(PMID:31015428)
FlyBase
PMID:31015428
NCBI chr11:119,067,818...119,081,972
Ensembl chr11:119,067,818...119,081,972
G
VPS18
VPS18 core subunit of CORVET and HOPS complexes
enables
IMP
(PMID:31015428)
FlyBase
PMID:31015428
NCBI chr15:40,894,450...40,903,975
Ensembl chr15:40,894,450...40,903,975
G
WDR24
WD repeat domain 24
enables
IDA
(PMID:36528027), (PMID:36732624)
UniProt
PMID:36528027 PMID:36732624
NCBI chr16:684,622...690,398
Ensembl chr16:684,622...690,444
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WSB1
WD repeat and SOCS box containing 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr17:27,294,114...27,315,926
Ensembl chr17:27,294,076...27,315,926
G
WWP1
WW domain containing E3 ubiquitin protein ligase 1
enables
IEA IBA
Ensembl TreeGrafter GO_Central InterPro
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr 8:86,342,547...86,468,503
Ensembl chr 8:86,342,547...86,478,420
G
WWP2
WW domain containing E3 ubiquitin protein ligase 2
enables
IEA IBA TAS
InterPro TreeGrafter GO_Central Reactome Ensembl
GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 Reactome:R-HSA-6807134 Reactome:R-HSA-9021523
NCBI chr16:69,762,332...69,941,739
Ensembl chr16:69,762,328...69,941,741
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XIAP
X-linked inhibitor of apoptosis
enables
EXP IEA IBA IDA TAS
(PMID:22304967) (PMID:29452636), (PMID:36394357), (PMID:36749823)
Reactome TreeGrafter GO_Central FlyBase
PMID:22304967 PMID:29452636 PMID:36394357 PMID:36749823
GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-6807134
NCBI chr X:123,859,708...123,913,972
Ensembl chr X:123,859,712...123,913,972
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ZNF598
zinc finger protein 598, E3 ubiquitin ligase
enables
IMP IBA IDA IEA
(PMID:28132843) (PMID:28065601), (PMID:28685749), (PMID:30293783), (PMID:36302773)
UniProt GO_Central InterPro
PMID:28065601 PMID:28132843 PMID:28685749 PMID:30293783 PMID:36302773
GO_REF:0000002 GO_REF:0000033
NCBI chr16:1,997,654...2,009,821
Ensembl chr16:1,997,654...2,009,821
G
ZNRF1
zinc and ring finger 1
enables
IEA IBA IDA
(PMID:22797923), (PMID:28593998), (PMID:37158982)
Ensembl GO_Central UniProt
PMID:22797923 PMID:28593998 PMID:37158982
GO_REF:0000033 GO_REF:0000107
NCBI chr16:74,999,024...75,110,994
Ensembl chr16:74,999,024...75,110,994
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ZNRF2
zinc and ring finger 2
enables
IDA IBA IEA
(PMID:22797923)
MGI GO_Central TreeGrafter
PMID:22797923
GO_REF:0000033 GO_REF:0000118
NCBI chr 7:30,284,597...30,367,689
Ensembl chr 7:30,284,597...30,367,689
G
ZNRF3
zinc and ring finger 3
enables
TAS IBA IEA
(PMID:24431302)
ParkinsonsUK-UCL GO_Central TreeGrafter
PMID:24431302
GO_REF:0000033 GO_REF:0000118
NCBI chr22:28,883,572...29,057,488
Ensembl chr22:28,883,572...29,057,488
G
ZNRF4
zinc and ring finger 4
enables
IDA IBA
(PMID:28656966)
UniProt GO_Central
PMID:28656966
GO_REF:0000033
NCBI chr19:5,455,417...5,456,856
Ensembl chr19:5,455,417...5,456,856
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ZSWIM2
zinc finger SWIM-type containing 2
enables
IEA
Ensembl InterPro
GO_REF:0000002 GO_REF:0000107
NCBI chr 2:186,827,475...186,849,170
Ensembl chr 2:186,827,475...186,849,208
G
UBR2
ubiquitin protein ligase E3 component n-recognin 2
enables
ISS
UniProt
GO_REF:0000024
NCBI chr 6:42,564,029...42,693,505
Ensembl chr 6:42,564,029...42,693,505
G
PCGF3
polycomb group ring finger 3
enables
IEA ISS
Ensembl UniProt
GO_REF:0000024 GO_REF:0000107
NCBI chr 4:705,832...770,089
Ensembl chr 4:705,748...770,089
G
PCGF5
polycomb group ring finger 5
enables
ISS IEA
UniProt Ensembl
GO_REF:0000024 GO_REF:0000107
NCBI chr10:91,156,219...91,284,337
Ensembl chr10:91,163,012...91,284,337
G
RNF2
ring finger protein 2
enables
IEA ISS
Ensembl UniProt
GO_REF:0000024 GO_REF:0000107
NCBI chr 1:185,045,558...185,102,603
Ensembl chr 1:185,045,497...185,102,603
G
TRIM37
tripartite motif containing 37
enables
IDA
(PMID:25470042)
UniProt
PMID:25470042
NCBI chr17:58,967,201...59,106,880
Ensembl chr17:58,982,638...59,106,921
G
RNF168
ring finger protein 168
enables
IDA
(PMID:27153538)
UniProt
PMID:27153538
NCBI chr 3:196,468,783...196,503,768
Ensembl chr 3:196,468,783...196,503,768
G
RNF20
ring finger protein 20
enables
IMP IEA
(PMID:16337599)
UniProt Ensembl
PMID:16337599
GO_REF:0000107
NCBI chr 9:101,533,853...101,563,344
Ensembl chr 9:101,533,853...101,563,344
G
MSL2
MSL complex subunit 2
enables
IDA
(PMID:21726816), (PMID:30930284)
UniProt
PMID:21726816 PMID:30930284
NCBI chr 3:136,148,917...136,196,335
Ensembl chr 3:136,148,917...136,197,241
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UHRF1
ubiquitin like with PHD and ring finger domains 1
enables
IEA ISS
Ensembl BHF-UCL
GO_REF:0000024 GO_REF:0000107
NCBI chr19:4,903,080...4,962,154
Ensembl chr19:4,903,080...4,962,154
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DTX3L
deltex E3 ubiquitin ligase 3L
enables
IDA
(PMID:19818714)
UniProt
PMID:19818714
NCBI chr 3:122,564,338...122,575,203
Ensembl chr 3:122,564,338...122,575,203
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DTX3L
deltex E3 ubiquitin ligase 3L
enables
IMP
(PMID:26479788)
UniProt
PMID:26479788
NCBI chr 3:122,564,338...122,575,203
Ensembl chr 3:122,564,338...122,575,203
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HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
enables
IDA
(PMID:15767685)
UniProt
PMID:15767685
NCBI chr X:53,532,096...53,686,719
Ensembl chr X:53,532,096...53,686,752
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RNF168
ring finger protein 168
enables
IDA
(PMID:19500350)
UniProt
PMID:19500350
NCBI chr 3:196,468,783...196,503,768
Ensembl chr 3:196,468,783...196,503,768
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UBR2
ubiquitin protein ligase E3 component n-recognin 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 6:42,564,029...42,693,505
Ensembl chr 6:42,564,029...42,693,505
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AMFR
autocrine motility factor receptor
enables
IDA
(PMID:24810856)
ParkinsonsUK-UCL
PMID:24810856
NCBI chr16:56,361,452...56,425,545
Ensembl chr16:56,361,452...56,425,545
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ANAPC11
anaphase promoting complex subunit 11
enables
IDA
(PMID:10230407)
MGI
PMID:10230407
NCBI chr17:81,890,790...81,900,533
Ensembl chr17:81,890,790...81,900,991
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PELI1
pellino E3 ubiquitin protein ligase 1
enables
TAS IDA
(PMID:30952868)
Reactome UniProt
PMID:30952868
Reactome:R-HSA-937050 Reactome:R-HSA-975122
NCBI chr 2:64,092,652...64,144,420
Ensembl chr 2:64,092,652...64,144,420
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PELI2
pellino E3 ubiquitin protein ligase family member 2
enables
TAS
Reactome
Reactome:R-HSA-937050 Reactome:R-HSA-975122
NCBI chr14:56,118,411...56,301,524
Ensembl chr14:56,117,814...56,301,524
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PPIL2
peptidylprolyl isomerase like 2
enables
IDA
(PMID:11435423)
MGI
PMID:11435423
NCBI chr22:21,666,012...21,700,015
Ensembl chr22:21,666,000...21,700,015
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PRPF19
pre-mRNA processing factor 19
enables
IDA
(PMID:11435423)
MGI
PMID:11435423
NCBI chr11:60,890,547...60,906,585
Ensembl chr11:60,890,547...60,906,585
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RBX1
ring-box 1
enables
IDA
(PMID:10230407)
MGI
PMID:10230407
NCBI chr22:40,951,378...40,973,309
Ensembl chr22:40,951,347...40,973,309
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RLIM
ring finger protein, LIM domain interacting
enables
IEA
TreeGrafter
GO_REF:0000118
NCBI chr X:74,582,976...74,614,624
Ensembl chr X:74,582,976...74,614,624
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STUB1
STIP1 homology and U-box containing protein 1
enables
ISS IEA
UniProt Ensembl
GO_REF:0000024 GO_REF:0000107
NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870
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TRAF6
TNF receptor associated factor 6
enables
IDA
(PMID:15465037)
UniProt
PMID:15465037
NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272
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UBE2K
ubiquitin conjugating enzyme E2 K
enables
IDA
(PMID:17873885)
UniProt
PMID:17873885
NCBI chr 4:39,698,136...39,782,792
Ensembl chr 4:39,698,109...39,782,792
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UBE4A
ubiquitination factor E4A
enables
IEA IBA
InterPro TreeGrafter GO_Central UniProt
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118
NCBI chr11:118,359,600...118,399,211
Ensembl chr11:118,359,600...118,399,211
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UBE4B
ubiquitination factor E4B
enables
IEA IBA
InterPro GO_Central TreeGrafter UniProt
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118
NCBI chr 1:10,032,958...10,181,239
Ensembl chr 1:10,032,832...10,181,239
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UBOX5
U-box domain containing 5
enables
IEA IBA ISS
Ensembl GO_Central TreeGrafter UniProt
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118
NCBI chr20:3,107,573...3,159,865
Ensembl chr20:3,107,573...3,160,196
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UBR5
ubiquitin protein ligase E3 component n-recognin 5
enables
IDA IBA IEA
(PMID:21118991)
BHF-UCL GO_Central TreeGrafter
PMID:21118991
GO_REF:0000033 GO_REF:0000118
NCBI chr 8:102,252,273...102,412,700
Ensembl chr 8:102,252,273...102,412,759
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all