TRIM77 (tripartite motif containing 77) - Rat Genome Database

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Gene: TRIM77 (tripartite motif containing 77) Homo sapiens
Analyze
Symbol: TRIM77
Name: tripartite motif containing 77
RGD ID: 2293601
HGNC Page HGNC:34228
Description: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to be active in cytoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: putative tripartite motif-containing protein 64D; putative tripartite motif-containing protein 77; TRIM77-isoform; TRIM77P; tripartite motif containing 77, pseudogene; tripartite motif-containing 77; tripartite motif-containing protein 77
RGD Orthologs
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Related Pseudogenes: TRIM77BP  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381189,710,299 - 89,717,872 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1189,710,299 - 89,717,872 (+)EnsemblGRCh38hg38GRCh38
GRCh371189,443,467 - 89,451,040 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361189,083,115 - 89,090,688 (+)NCBINCBI36Build 36hg18NCBI36
Celera1185,180,362 - 85,187,935 (-)NCBICelera
Cytogenetic Map11q14.3NCBI
HuRef1185,680,608 - 85,688,175 (+)NCBIHuRef
CHM1_11189,326,347 - 89,333,928 (+)NCBICHM1_1
T2T-CHM13v2.01189,629,984 - 89,637,554 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
aflatoxin B1  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16554811   PMID:21873635   PMID:22144910   PMID:30021884  


Genomics

Comparative Map Data
TRIM77
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381189,710,299 - 89,717,872 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1189,710,299 - 89,717,872 (+)EnsemblGRCh38hg38GRCh38
GRCh371189,443,467 - 89,451,040 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361189,083,115 - 89,090,688 (+)NCBINCBI36Build 36hg18NCBI36
Celera1185,180,362 - 85,187,935 (-)NCBICelera
Cytogenetic Map11q14.3NCBI
HuRef1185,680,608 - 85,688,175 (+)NCBIHuRef
CHM1_11189,326,347 - 89,333,928 (+)NCBICHM1_1
T2T-CHM13v2.01189,629,984 - 89,637,554 (+)NCBIT2T-CHM13v2.0
TRIM77
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2990,583,308 - 90,591,022 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11191,627,339 - 91,635,047 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01184,714,995 - 84,722,708 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11149,659,553 - 49,667,096 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1149,659,553 - 49,667,096 (-)Ensemblpanpan1.1panPan2
LOC485141
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12110,296,651 - 10,323,858 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2110,296,680 - 10,321,543 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2110,179,428 - 10,185,163 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02110,478,284 - 10,484,020 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2110,478,284 - 10,484,020 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12110,272,960 - 10,278,695 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02110,332,017 - 10,337,559 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02110,382,061 - 10,387,785 (-)NCBIUU_Cfam_GSD_1.0
LOC106504145
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl923,079,377 - 23,090,598 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1923,080,180 - 23,095,529 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2925,817,850 - 25,828,292 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM77
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1180,881,033 - 80,889,905 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl180,881,379 - 80,889,095 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604344,853,371 - 44,861,299 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in TRIM77
26 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q14.1-22.3(chr11:78232836-106779420)x1 copy number loss See cases [RCV000052710] Chr11:78232836..106779420 [GRCh38]
Chr11:77943882..106650146 [GRCh37]
Chr11:77621530..106155356 [NCBI36]
Chr11:11q14.1-22.3
pathogenic
GRCh38/hg38 11q14.1-22.2(chr11:85242847-102920097)x1 copy number loss See cases [RCV000052711] Chr11:85242847..102920097 [GRCh38]
Chr11:84953891..102738968 [GRCh37]
Chr11:84631539..102296037 [NCBI36]
Chr11:11q14.1-22.2
pathogenic
GRCh38/hg38 11q13.5-22.1(chr11:75941754-98357960)x1 copy number loss See cases [RCV000133838] Chr11:75941754..98357960 [GRCh38]
Chr11:75652798..98228688 [GRCh37]
Chr11:75330446..97733898 [NCBI36]
Chr11:11q13.5-22.1
pathogenic
GRCh38/hg38 11q14.3(chr11:89650515-90084741)x1 copy number loss See cases [RCV000137458] Chr11:89650515..90084741 [GRCh38]
Chr11:89383683..89817909 [GRCh37]
Chr11:89023331..89457557 [NCBI36]
Chr11:11q14.3
pathogenic|likely benign
GRCh38/hg38 11q14.3(chr11:89613604-89898870)x1 copy number loss See cases [RCV000140663] Chr11:89613604..89898870 [GRCh38]
Chr11:89346772..89632038 [GRCh37]
Chr11:88986420..89271686 [NCBI36]
Chr11:11q14.3
uncertain significance
GRCh38/hg38 11q14.3(chr11:89425778-90689442)x1 copy number loss See cases [RCV000141934] Chr11:89425778..90689442 [GRCh38]
Chr11:89158946..90422610 [GRCh37]
Chr11:88798594..90062258 [NCBI36]
Chr11:11q14.3
uncertain significance
GRCh37/hg19 11q14.1-21(chr11:80318996-96116221)x1 copy number loss See cases [RCV000446395] Chr11:80318996..96116221 [GRCh37]
Chr11:11q14.1-21
pathogenic
GRCh37/hg19 11q14.2-14.3(chr11:87099219-91921385) copy number loss Abnormal esophagus morphology [RCV000416734] Chr11:87099219..91921385 [GRCh37]
Chr11:11q14.2-14.3
likely benign
GRCh37/hg19 11q14.1-21(chr11:84924674-93574799)x1 copy number loss See cases [RCV000448436] Chr11:84924674..93574799 [GRCh37]
Chr11:11q14.1-21
likely pathogenic
GRCh37/hg19 11q14.2-22.3(chr11:88152458-109414650)x1 copy number loss See cases [RCV000510457] Chr11:88152458..109414650 [GRCh37]
Chr11:11q14.2-22.3
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
NM_001146162.1(TRIM77):c.556G>A (p.Val186Met) single nucleotide variant Inborn genetic diseases [RCV003253380] Chr11:89714240 [GRCh38]
Chr11:89447408 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.572G>A (p.Arg191His) single nucleotide variant Inborn genetic diseases [RCV003251695] Chr11:89714256 [GRCh38]
Chr11:89447424 [GRCh37]
Chr11:11q14.3
uncertain significance
GRCh37/hg19 11q13.4-23.3(chr11:71588805-116680918)x3 copy number gain not provided [RCV000683374] Chr11:71588805..116680918 [GRCh37]
Chr11:11q13.4-23.3
pathogenic
GRCh37/hg19 11q14.1-14.3(chr11:81771852-90851187) copy number loss Intellectual disability [RCV000721939] Chr11:81771852..90851187 [GRCh37]
Chr11:11q14.1-14.3
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11q14.1-23.2(chr11:80053454-113316236)x1 copy number loss not provided [RCV000737595] Chr11:80053454..113316236 [GRCh37]
Chr11:11q14.1-23.2
pathogenic
GRCh37/hg19 11q14.3(chr11:89276166-89622304)x3 copy number gain not provided [RCV000737619] Chr11:89276166..89622304 [GRCh37]
Chr11:11q14.3
benign
GRCh37/hg19 11q14.3(chr11:89322065-89486848)x3 copy number gain not provided [RCV000737620] Chr11:89322065..89486848 [GRCh37]
Chr11:11q14.3
benign
GRCh37/hg19 11q14.1-21(chr11:83179196-94716998)x3 copy number gain not provided [RCV000750120] Chr11:83179196..94716998 [GRCh37]
Chr11:11q14.1-21
pathogenic
GRCh37/hg19 11q14.3(chr11:89071360-89543740)x3 copy number gain not provided [RCV001006432] Chr11:89071360..89543740 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.935G>T (p.Ser312Ile) single nucleotide variant Inborn genetic diseases [RCV003272252] Chr11:89717454 [GRCh38]
Chr11:89450622 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.592G>A (p.Val198Ile) single nucleotide variant Inborn genetic diseases [RCV003274945] Chr11:89714276 [GRCh38]
Chr11:89447444 [GRCh37]
Chr11:11q14.3
uncertain significance
GRCh37/hg19 11q14.3(chr11:89062443-89762600)x3 copy number gain not provided [RCV001006431] Chr11:89062443..89762600 [GRCh37]
Chr11:11q14.3
likely benign
GRCh37/hg19 11q14.1-14.3(chr11:84830143-92029933)x3 copy number gain not provided [RCV001006426] Chr11:84830143..92029933 [GRCh37]
Chr11:11q14.1-14.3
pathogenic
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3
pathogenic
GRCh37/hg19 11q14.1-22.1(chr11:77855209-98002445) copy number loss not specified [RCV002052940] Chr11:77855209..98002445 [GRCh37]
Chr11:11q14.1-22.1
pathogenic
GRCh37/hg19 11q14.1-21(chr11:80318996-96116221) copy number loss not specified [RCV002052941] Chr11:80318996..96116221 [GRCh37]
Chr11:11q14.1-21
pathogenic
GRCh37/hg19 11q14.1-21(chr11:84924674-93574799) copy number loss not specified [RCV002052942] Chr11:84924674..93574799 [GRCh37]
Chr11:11q14.1-21
likely pathogenic
GRCh37/hg19 11q14.1-23.3(chr11:85422071-118022671)x1 copy number loss not provided [RCV001832892] Chr11:85422071..118022671 [GRCh37]
Chr11:11q14.1-23.3
uncertain significance
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25
pathogenic
NM_001146162.1(TRIM77):c.751G>A (p.Val251Ile) single nucleotide variant Inborn genetic diseases [RCV003282796] Chr11:89715170 [GRCh38]
Chr11:89448338 [GRCh37]
Chr11:11q14.3
likely benign
NM_001146162.1(TRIM77):c.614G>A (p.Gly205Asp) single nucleotide variant Inborn genetic diseases [RCV002906023] Chr11:89714298 [GRCh38]
Chr11:89447466 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.1006C>G (p.Leu336Val) single nucleotide variant Inborn genetic diseases [RCV003012650] Chr11:89717525 [GRCh38]
Chr11:89450693 [GRCh37]
Chr11:11q14.3
uncertain significance
GRCh37/hg19 11q14.1-22.3(chr11:81478509-104667040)x1 copy number loss not provided [RCV002475722] Chr11:81478509..104667040 [GRCh37]
Chr11:11q14.1-22.3
pathogenic
NM_001146162.1(TRIM77):c.372C>A (p.His124Gln) single nucleotide variant Inborn genetic diseases [RCV002869232] Chr11:89710670 [GRCh38]
Chr11:89443838 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.563A>C (p.Gln188Pro) single nucleotide variant Inborn genetic diseases [RCV002886921] Chr11:89714247 [GRCh38]
Chr11:89447415 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.545A>T (p.Glu182Val) single nucleotide variant Inborn genetic diseases [RCV002910294] Chr11:89714229 [GRCh38]
Chr11:89447397 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.869C>T (p.Thr290Ile) single nucleotide variant Inborn genetic diseases [RCV002983970] Chr11:89717388 [GRCh38]
Chr11:89450556 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.13A>G (p.Ile5Val) single nucleotide variant Inborn genetic diseases [RCV002666096] Chr11:89710311 [GRCh38]
Chr11:89443479 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.524G>A (p.Arg175Gln) single nucleotide variant Inborn genetic diseases [RCV002708858] Chr11:89714208 [GRCh38]
Chr11:89447376 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.748G>A (p.Asp250Asn) single nucleotide variant Inborn genetic diseases [RCV002941270] Chr11:89715167 [GRCh38]
Chr11:89448335 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.1342G>A (p.Gly448Arg) single nucleotide variant Inborn genetic diseases [RCV002855560] Chr11:89717861 [GRCh38]
Chr11:89451029 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.445A>G (p.Lys149Glu) single nucleotide variant Inborn genetic diseases [RCV002722518] Chr11:89711443 [GRCh38]
Chr11:89444611 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.17C>T (p.Thr6Met) single nucleotide variant Inborn genetic diseases [RCV003179640] Chr11:89710315 [GRCh38]
Chr11:89443483 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.247T>G (p.Cys83Gly) single nucleotide variant Inborn genetic diseases [RCV003183211] Chr11:89710545 [GRCh38]
Chr11:89443713 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.1275A>C (p.Gln425His) single nucleotide variant Inborn genetic diseases [RCV003285636] Chr11:89717794 [GRCh38]
Chr11:89450962 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.1271C>T (p.Ala424Val) single nucleotide variant Inborn genetic diseases [RCV003374550] Chr11:89717790 [GRCh38]
Chr11:89450958 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.1030G>A (p.Glu344Lys) single nucleotide variant Inborn genetic diseases [RCV003353354] Chr11:89717549 [GRCh38]
Chr11:89450717 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.1031A>G (p.Glu344Gly) single nucleotide variant Inborn genetic diseases [RCV003353355] Chr11:89717550 [GRCh38]
Chr11:89450718 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.793C>T (p.Pro265Ser) single nucleotide variant Inborn genetic diseases [RCV003356341] Chr11:89715921 [GRCh38]
Chr11:89449089 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001146162.1(TRIM77):c.76G>C (p.Val26Leu) single nucleotide variant Inborn genetic diseases [RCV003349452] Chr11:89710374 [GRCh38]
Chr11:89443542 [GRCh37]
Chr11:11q14.3
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:447
Count of miRNA genes:287
Interacting mature miRNAs:302
Transcripts:ENST00000398290, ENST00000534392, ENST00000603145
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium
Low 3 1 2 4
Below cutoff 23 26 63 50 25 49 70 21 106 4 219 29 1 8 35

Sequence


RefSeq Acc Id: ENST00000398290   ⟹   ENSP00000474003
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,710,299 - 89,717,872 (+)Ensembl
RefSeq Acc Id: ENST00000534392   ⟹   ENSP00000474353
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,710,650 - 89,717,806 (+)Ensembl
RefSeq Acc Id: NM_001146162   ⟹   NP_001139634
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,710,299 - 89,717,872 (+)NCBI
GRCh371189,443,467 - 89,451,040 (+)RGD
Celera1185,180,362 - 85,187,935 (-)RGD
HuRef1185,680,608 - 85,688,175 (+)ENTREZGENE
CHM1_11189,326,347 - 89,333,928 (+)NCBI
T2T-CHM13v2.01189,629,984 - 89,637,554 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001271942   ⟹   NP_001258871
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,710,299 - 89,717,872 (+)NCBI
GRCh371189,443,467 - 89,451,040 (+)NCBI
HuRef1185,680,608 - 85,688,175 (+)NCBI
CHM1_11189,326,347 - 89,333,928 (+)NCBI
T2T-CHM13v2.01189,629,984 - 89,637,554 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001139634 (Get FASTA)   NCBI Sequence Viewer  
  NP_001258871 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AFI99088 (Get FASTA)   NCBI Sequence Viewer  
  AFI99089 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000474003
  ENSP00000474003.1
  ENSP00000474353.1
GenBank Protein I1YAP6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001139634   ⟸   NM_001146162
- Peptide Label: isoform 1
- UniProtKB: I1YAP6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001258871   ⟸   NM_001271942
- Peptide Label: isoform 2
- UniProtKB: I1YAP7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000474003   ⟸   ENST00000398290
RefSeq Acc Id: ENSP00000474353   ⟸   ENST00000534392
Protein Domains
B30.2/SPRY

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-I1YAP6-F1-model_v2 AlphaFold I1YAP6 1-450 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:34228 AgrOrtholog
COSMIC TRIM77 COSMIC
Ensembl Genes ENSG00000214414 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000398290 ENTREZGENE
  ENST00000398290.7 UniProtKB/Swiss-Prot
  ENST00000534392.4 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/Swiss-Prot
  Classic Zinc Finger UniProtKB/Swiss-Prot
GTEx ENSG00000214414 GTEx
HGNC ID HGNC:34228 ENTREZGENE
Human Proteome Map TRIM77 Human Proteome Map
InterPro B30.2/SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_B-box UniProtKB/Swiss-Prot
  Znf_C3HC4_RING-type UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
  Znf_RING_CS UniProtKB/Swiss-Prot
KEGG Report hsa:390231 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 390231 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRIPARTITE MOTIF-CONTAINING PROTEIN 77 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/Swiss-Prot
PharmGKB PA162407029 PharmGKB
PRINTS BUTYPHLNCDUF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/Swiss-Prot
  ZF_RING_1 UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
SMART BBOX UniProtKB/Swiss-Prot
  RING UniProtKB/Swiss-Prot
Superfamily-SCOP B-box zinc-binding domain UniProtKB/Swiss-Prot
  RING/U-box UniProtKB/Swiss-Prot
  SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt I1YAP6 ENTREZGENE
  I1YAP7 ENTREZGENE, UniProtKB/TrEMBL
  S4R3H6_HUMAN UniProtKB/TrEMBL
  TRI77_HUMAN UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-22 TRIM77  tripartite motif containing 77  TRIM77P  tripartite motif containing 77, pseudogene  Symbol and/or name change 5135510 APPROVED
2011-07-27 TRIM77P  tripartite motif containing 77, pseudogene  TRIM77  tripartite motif-containing 77  Symbol and/or name change 5135510 APPROVED