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Gene: UBE3D (ubiquitin protein ligase E3D) Homo sapiens
Symbol: UBE3D
Name: ubiquitin protein ligase E3D
Description: Exhibits cyclin binding activity; ubiquitin protein ligase activity; and ubiquitin-like protein conjugating enzyme binding activity. Involved in protein autoubiquitination; protein monoubiquitination; and protein polyubiquitination. Localizes to ubiquitin ligase complex; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C6orf157; DKFZp434A1520; E3 ubiquitin-protein ligase E3D; H10BH; HECT-type E3 ubiquitin transferase E3D; MGC126561; MGC126587; UBCH10 binding protein with a hect-like domain; ubcH10-binding protein with a HECT-like domain; UBE2CBP; ubiquitin-conjugating enzyme E2C binding protein; ubiquitin-conjugating enzyme E2C-binding protein; YJR141W
Mus musculus (house mouse) : Ube2cbp (ubiquitin-conjugating enzyme E2C binding protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ube3d (ubiquitin protein ligase E3D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ube3d (ubiquitin protein ligase E3D)
Pan paniscus (bonobo/pygmy chimpanzee) : UBE3D (ubiquitin protein ligase E3D)
Canis lupus familiaris (dog) : UBE3D (ubiquitin protein ligase E3D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ube3d (ubiquitin protein ligase E3D)
Sus scrofa (pig) : UBE3D (ubiquitin protein ligase E3D)
Chlorocebus sabaeus (African green monkey) : UBE3D (ubiquitin protein ligase E3D)
Heterocephalus glaber (naked mole-rat) : Ube3d (ubiquitin protein ligase E3D)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl682,892,390 - 83,065,841 (-)EnsemblGRCh38hg38GRCh38
GRCh38682,880,834 - 83,065,841 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37683,602,186 - 83,775,545 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36683,658,905 - 83,832,264 (-)NCBINCBI36hg18NCBI36
Celera684,035,429 - 84,208,843 (-)NCBI
Cytogenetic Map6q14.1NCBI
HuRef680,830,086 - 81,003,588 (-)NCBIHuRef
CHM1_1683,699,747 - 83,873,239 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on UBE3D
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315581
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.