FBXL22 (F-box and leucine rich repeat protein 22)

Gene: FBXL22 (F-box and leucine rich repeat protein 22) Homo sapiens

Analyze

Symbol:

FBXL22

Name:

F-box and leucine rich repeat protein 22

RGD ID:

1350469

HGNC Page

HGNC:27537

Description:

Enables ubiquitin protein ligase activity. Acts upstream of or within proteasome-mediated ubiquitin-dependent protein catabolic process. Located in cytosol and nucleolus.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

F-box and leucine-rich protein 22; F-box and leucine-rich repeat protein 22; F-box/LRR-repeat protein 22; Fbl22; FLJ39626; MGC75496

RGD Orthologs

Alliance Genes

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	63,597,387 - 63,608,516 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	63,597,353 - 63,602,428 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	63,889,586 - 63,895,631 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	61,676,649 - 61,681,680 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	61,676,648 - 61,681,671	NCBI
Celera	15	40,768,998 - 40,774,059 (+)	NCBI		Celera
Cytogenetic Map	15	q22.31	NCBI
HuRef	15	40,713,981 - 40,719,056 (+)	NCBI		HuRef
CHM1_1	15	64,008,778 - 64,013,853 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	61,404,626 - 61,415,756 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (IAGP)

colorectal cancer (IAGP)

genetic disease (IAGP)

hypertrophic cardiomyopathy (IAGP)

nemaline myopathy 6 (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (ISO)

aflatoxin B1 (EXP)

amitrole (ISO)

amphetamine (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (ISO)

bisphenol F (ISO)

butanal (EXP)

cantharidin (ISO)

CGP 52608 (EXP)

chlorpyrifos (ISO)

diiodine (ISO)

dimethylarsinic acid (ISO)

diuron (ISO)

doxorubicin (EXP)

fenvalerate (ISO)

furan (ISO)

ketamine (ISO)

methimazole (ISO)

methylarsonic acid (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-methyl-4-phenylpyridinium (ISO)

ozone (EXP)

propiconazole (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (ISO)

sodium fluoride (ISO)

sulfadimethoxine (ISO)

sunitinib (EXP)

thioacetamide (ISO)

titanium dioxide (ISO)

triclosan (EXP)

triphenyl phosphate (EXP)

triptonide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proteasome-mediated ubiquitin-dependent protein catabolic process (IDA)

protein ubiquitination (IEA)

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IDA,TAS)

nucleolus (IDA)

SCF ubiquitin ligase complex (IEA)

Z disc (IEA)

Molecular Function

protein binding (IPI)

ubiquitin protein ligase activity (IDA)

Phenotype Annotations Click to see Annotation Detail View

Human Phenotype

Hypertrophic cardiomyopathy (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
2.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11076863	PMID:14702039	PMID:15489334	PMID:15489336	PMID:15520277	PMID:16381901	PMID:19028597	PMID:20379614	PMID:21873635	PMID:22972877	PMID:24324551	PMID:32296183
PMID:33961781

Genomics

Comparative Map Data

FBXL22
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	63,597,387 - 63,608,516 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	63,597,353 - 63,602,428 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	63,889,586 - 63,895,631 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	61,676,649 - 61,681,680 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	61,676,648 - 61,681,671	NCBI
Celera	15	40,768,998 - 40,774,059 (+)	NCBI		Celera
Cytogenetic Map	15	q22.31	NCBI
HuRef	15	40,713,981 - 40,719,056 (+)	NCBI		HuRef
CHM1_1	15	64,008,778 - 64,013,853 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	61,404,626 - 61,415,756 (+)	NCBI		T2T-CHM13v2.0

Fbxl22
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	66,415,738 - 66,425,752 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	66,415,657 - 66,421,891 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	66,508,459 - 66,514,593 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	66,508,375 - 66,514,609 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	66,356,266 - 66,362,400 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	66,306,465 - 66,312,582 (-)	NCBI		MGSCv36	mm8
Celera	9	63,742,425 - 63,748,560 (-)	NCBI		Celera
Cytogenetic Map	9	C	NCBI
cM Map	9	35.96	NCBI

Fbxl22
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	75,965,027 - 75,971,714 (-)	NCBI		GRCr8
mRatBN7.2	8	67,069,998 - 67,076,685 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	67,069,998 - 67,076,685 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	72,582,388 - 72,589,075 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	70,855,209 - 70,861,896 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	68,725,550 - 68,732,237 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	72,198,043 - 72,204,730 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	72,198,043 - 72,204,730 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	71,865,760 - 71,872,447 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	70,811,502 - 70,818,189 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	70,834,212 - 70,837,241 (-)	NCBI
Celera	8	66,455,578 - 66,462,265 (-)	NCBI		Celera
Cytogenetic Map	8	q24	NCBI

Fbxl22
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955450	11,719,678 - 11,728,093 (-)	NCBI	ChiLan1.0	ChiLan1.0

FBXL22
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	52,845,341 - 52,854,100 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	57,021,343 - 57,030,221 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	42,543,909 - 42,548,938 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	60,837,032 - 60,841,840 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	60,837,032 - 60,841,829 (+)	Ensembl	panpan1.1		panPan2

FBXL22
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	28,187,452 - 28,191,019 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	28,187,473 - 28,191,004 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	28,108,243 - 28,111,834 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	28,361,496 - 28,365,088 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	28,361,556 - 28,365,088 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	28,298,870 - 28,302,447 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	28,361,168 - 28,364,758 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	28,599,333 - 28,602,918 (+)	NCBI		UU_Cfam_GSD_1.0

Fbxl22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	106,284,463 - 106,288,271 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	24,132,226 - 24,136,676 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	24,131,046 - 24,139,835 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FBXL22
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	108,408,995 - 108,411,768 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	108,408,227 - 108,411,937 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

FBXL22
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	19,937,405 - 19,944,579 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666048	121,456,514 - 121,461,642 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fbxl22
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624781	8,910,857 - 8,915,069 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624781	8,910,778 - 8,915,393 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in FBXL22
15 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 15q22.2-26.3(chr15:59828460-101920998)x3	copy number gain	See cases [RCV000142915]	Chr15:59828460..101920998 [GRCh38] Chr15:60120659..102461201 [GRCh37] Chr15:57907951..100278724 [NCBI36] Chr15:15q22.2-26.3	pathogenic
Single allele	deletion	Nemaline myopathy 6 [RCV000677940]	Chr15:63414894..66439797 [GRCh37] Chr15:15q22.2-22.31	likely pathogenic
GRCh37/hg19 15q22.1-26.3(chr15:59297293-102480888)x3	copy number gain	not provided [RCV000415836]	Chr15:59297293..102480888 [GRCh37] Chr15:15q22.1-26.3	likely pathogenic
GRCh37/hg19 15q15.1-26.3(chr15:41745084-102354798)x4	copy number gain	See cases [RCV000447123]	Chr15:41745084..102354798 [GRCh37] Chr15:15q15.1-26.3	pathogenic
GRCh37/hg19 15q11.2-26.3(chr15:20733395-102511616)x4	copy number gain	See cases [RCV000447765]	Chr15:20733395..102511616 [GRCh37] Chr15:15q11.2-26.3	pathogenic
GRCh37/hg19 15q11.2-26.3(chr15:22770422-102429112)x3	copy number gain	See cases [RCV000510717]	Chr15:22770422..102429112 [GRCh37] Chr15:15q11.2-26.3	pathogenic
GRCh37/hg19 15q11.2-26.3(chr15:22770422-102429112)	copy number gain	See cases [RCV000512019]	Chr15:22770422..102429112 [GRCh37] Chr15:15q11.2-26.3	pathogenic
NM_001367807.1(FBXL22):c.206C>G (p.Pro69Arg)	single nucleotide variant	Inborn genetic diseases [RCV003287574]	Chr15:63597598 [GRCh38] Chr15:63889797 [GRCh37] Chr15:15q22.31	uncertain significance
Single allele	duplication	not provided [RCV000677926]	Chr15:31115047..102354857 [GRCh37] Chr15:15q13.2-26.3	pathogenic
GRCh37/hg19 15q11.1-26.3(chr15:20016811-102493540)x3	copy number gain	not provided [RCV000751155]	Chr15:20016811..102493540 [GRCh37] Chr15:15q11.1-26.3	pathogenic
GRCh37/hg19 15q11.1-26.3(chr15:20071673-102461162)x3	copy number gain	not provided [RCV000751156]	Chr15:20071673..102461162 [GRCh37] Chr15:15q11.1-26.3	pathogenic
NM_203373.3(FBXL22):c.739C>T (p.Gln247Ter)	single nucleotide variant	not provided [RCV000891661]	Chr15:63601681 [GRCh38] Chr15:63893880 [GRCh37] Chr15:15q22.31	benign
NC_000015.9:g.(?_62146656)_(64747263_?)del	deletion	not provided [RCV003107781]	Chr15:62146656..64747263 [GRCh37] Chr15:15q22.2-22.31	pathogenic
NC_000015.10:g.(?_63042820)_(63869153_?)dup	duplication	Hypertrophic cardiomyopathy [RCV001033641]	Chr15:63335019..64161352 [GRCh37] Chr15:15q22.2-22.31	uncertain significance
NC_000015.9:g.(?_63335019)_(64161352_?)dup	duplication	Hypertrophic cardiomyopathy [RCV001304134]	Chr15:63335019..64161352 [GRCh37] Chr15:15q22.2-22.31	uncertain significance
NC_000015.9:g.(?_32964879)_(91358519_?)dup	duplication	Bloom syndrome [RCV001343104]\|Familial colorectal cancer [RCV001325176]	Chr15:32964879..91358519 [GRCh37] Chr15:15q13.3-26.1	uncertain significance
NM_001367807.1(FBXL22):c.251A>G (p.Gln84Arg)	single nucleotide variant	Inborn genetic diseases [RCV002793933]	Chr15:63597643 [GRCh38] Chr15:63889842 [GRCh37] Chr15:15q22.31	uncertain significance
NM_203373.3(FBXL22):c.614C>T (p.Ser205Leu)	single nucleotide variant	Inborn genetic diseases [RCV002841937]	Chr15:63601556 [GRCh38] Chr15:63893755 [GRCh37] Chr15:15q22.31	uncertain significance
NM_203373.3(FBXL22):c.652A>G (p.Arg218Gly)	single nucleotide variant	Inborn genetic diseases [RCV002907135]	Chr15:63601594 [GRCh38] Chr15:63893793 [GRCh37] Chr15:15q22.31	uncertain significance
NM_203373.3(FBXL22):c.562G>C (p.Ala188Pro)	single nucleotide variant	Inborn genetic diseases [RCV002778699]	Chr15:63601504 [GRCh38] Chr15:63893703 [GRCh37] Chr15:15q22.31	uncertain significance
NM_203373.3(FBXL22):c.496G>A (p.Ala166Thr)	single nucleotide variant	Inborn genetic diseases [RCV002901095]	Chr15:63601438 [GRCh38] Chr15:63893637 [GRCh37] Chr15:15q22.31	uncertain significance
NM_203373.3(FBXL22):c.479G>T (p.Arg160Leu)	single nucleotide variant	Inborn genetic diseases [RCV002705139]	Chr15:63601421 [GRCh38] Chr15:63893620 [GRCh37] Chr15:15q22.31	uncertain significance
NM_001367807.1(FBXL22):c.313G>C (p.Glu105Gln)	single nucleotide variant	Inborn genetic diseases [RCV002697597]	Chr15:63597705 [GRCh38] Chr15:63889904 [GRCh37] Chr15:15q22.31	uncertain significance
NM_001367807.1(FBXL22):c.215G>A (p.Arg72His)	single nucleotide variant	Inborn genetic diseases [RCV002641030]	Chr15:63597607 [GRCh38] Chr15:63889806 [GRCh37] Chr15:15q22.31	uncertain significance
NM_001367807.1(FBXL22):c.167C>T (p.Ser56Phe)	single nucleotide variant	Inborn genetic diseases [RCV002873960]	Chr15:63597559 [GRCh38] Chr15:63889758 [GRCh37] Chr15:15q22.31	uncertain significance
NM_001367807.1(FBXL22):c.281G>A (p.Ser94Asn)	single nucleotide variant	Inborn genetic diseases [RCV002956900]	Chr15:63597673 [GRCh38] Chr15:63889872 [GRCh37] Chr15:15q22.31	uncertain significance
NM_001367807.1(FBXL22):c.163C>A (p.Arg55Ser)	single nucleotide variant	Inborn genetic diseases [RCV003205028]	Chr15:63597555 [GRCh38] Chr15:63889754 [GRCh37] Chr15:15q22.31	uncertain significance
NM_203373.3(FBXL22):c.694A>G (p.Thr232Ala)	single nucleotide variant	Inborn genetic diseases [RCV003377453]	Chr15:63601636 [GRCh38] Chr15:63893835 [GRCh37] Chr15:15q22.31	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1155
Count of miRNA genes:	602
Interacting mature miRNAs:	683
Transcripts:	ENST00000360587, ENST00000534939, ENST00000539570, ENST00000560325
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

WI-14801

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	15	63,891,567 - 63,891,716	UniSTS	GRCh37
Build 36	15	61,678,620 - 61,678,769	RGD	NCBI36
Celera	15	40,770,969 - 40,771,118	RGD
Cytogenetic Map	15	q22.31	UniSTS
HuRef	15	40,715,996 - 40,716,145	UniSTS
GeneMap99-GB4 RH Map	15	221.7	UniSTS
Whitehead-RH Map	15	223.2	UniSTS
NCBI RH Map	15	372.8	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

adipose tissue

appendage

entire extraembryonic component

pharyngeal arch

High

Medium

1326

1192

608

689

401

559

Low

1031

982

1134

237

729

2756

1020

3157

296

973

1360

151

825

1657

Below cutoff

755

563

362

1105

351

988

486

545

105

244

328

572

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NG_027784	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001367807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001367808	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001367809	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_203373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006720478	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011521468	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011521469	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011521472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047432400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054377749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AA495872	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC118274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK096945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC065833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068263	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000360587 ⟹ ENSP00000353794

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	15	63,597,353 - 63,602,428 (+)	Ensembl

RefSeq Acc Id:

ENST00000534939 ⟹ ENSP00000453697

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	15	63,597,391 - 63,601,241 (+)	Ensembl

RefSeq Acc Id:

ENST00000560325 ⟹ ENSP00000473666

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	15	63,597,702 - 63,601,605 (+)	Ensembl

RefSeq Acc Id:

ENST00000638704 ⟹ ENSP00000492359

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	15	63,597,387 - 63,601,241 (+)	Ensembl

RefSeq Acc Id:

NM_001367807 ⟹ NP_001354736

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	15	63,597,387 - 63,601,241 (+)	NCBI
T2T-CHM13v2.0	15	61,404,626 - 61,408,480 (+)	NCBI

Sequence:

show sequence

ACTCACATGTGGCCACTGCTCACCATGCACATAACCCAGCTCAACCGGGAGTGCCTGCTGCACC
TCTTCTCCTTCCTAGACAAGGACAGCAGGAAGAGCCTTGCCAGGACCTGCTCCCAGCTCCACGA
CGTGTTTGAGGACCCCGCACTCTGGTCCCTGCTGCACTTCCGTTCCCTCACTGAACTCCAGAAG
GACAACTTCCTCCTGGGCCCGGCACTCCGCAGCCTCTCCATCTGCTGGCACTCCAGCCGCGTGC
AGGTGTGCAGCATTGAGGACTGGCTCAAGAGTGCCTTCCAGAGAAGCATCTGCAGCCGGCACGA
GAGCCTGGTCAATGATTTCCTCCTCCGGGTGTGCGACAGGTGCCCCAACCTGGCGTCCGTCACG
CTCTCGGGCTGCGGCCACGTTACCGACGACTGCCTGGCGCGCCTGCTGCGCTGCTGCCCACGCC
TGCGCGCACTGCGCCTGGAGAACTGCGCGCGCGTCACCAACCGCACGTTGGCTGCCGTGGCGGC
GGACGGGCGCGCGCTGCAGACATTGCACGTGGACTTCTGCCGCAACGTGAGCGCGGCCGGCCTG
CGCCGCCTGCGCGCCGCGTGCCCGCGCCTGGCCCTGCGGGCAGAGCACAGCGCCGCCATGCTGC
CCGACCAGCCCCCGCGCCCGCGCGCGCCCGCCGCGGCCCTCGGCAAGCTGCTGCAGCGCTAGAC
GCCGCCCCGCCGCTGCCCCCGGGGAAGGAGCGCAGCCCCAGACCGTCCTGGCTTCGAACCCAGC
TCTTCCACCTTCAGACCACCACCGCATATTCTGAGCCTCATTTTCCCCGTCTGCACAGTGGGGA
TAAGAAAGCCTACCTCACGTTACGATTTTATACATAGGATAAACGCAAGATTAAATGGATATTT
GGAAAACA

hide sequence

RefSeq Acc Id:

NM_001367808 ⟹ NP_001354737

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	15	63,597,387 - 63,601,241 (+)	NCBI
T2T-CHM13v2.0	15	61,404,626 - 61,408,480 (+)	NCBI

Sequence:

show sequence

ACTCACATGTGGCCACTGCTCACCATGCACATAACCCAGCTCAACCGGGAGTGCCTGCTGCACC
TCTTCTCCTTCCTAGACAAGGACAGCAGGAAGAGCCTTGCCAGGACCTGCTCCCAGCTCCACGA
CGTGTTTGAGGACCCCGCACTCTGGTCCCTGCTGCACTTCCGTTCCCTCACTGAACTCCAGAAG
GACAACTTCCTCCTGGGCCCGGCACTCCGCAGCCTCTCCATCTGCTGGCACTCCAGCCGCGTGC
AGGTGTGCAGCATTGAGGACTGGCTCAAGAGTGCCTTCCAGAGAAGCATCTGCAGCCGGCACGA
GAGCCTGGTCAATGATTTCCTCCTCCGGGTGTGCGACAGGGTAAGAGGATTAAATGACACAGTG
GCACCTGGCACATAGTAGGTACTGATGAACGTCTACTGAATCTGGTTCTTCTGGCACTCAGCTC
AGGTCGGGAGGAATGGCTGAGGATGGCTGGGCAGGGGGACAGTCCGCTCTTTGTTTTTTCCCTG
TATCAGAATTATTCCAAAGATTCTTAGAAGAAAAGATCACCCAACACCTTTGAGGCTTAAACAC
CTAATCCTTATAACCACCTTGAAGGTAACAATTCCTCCCACTTGACAAATGAGGAAGTGACGCC
CAGCAAGGTTCAGACATCTGTCCTGGGTCTGACAGCAAATAAGTCACCAGCCAGTCACCTGAGC
TGCCGGAGCCAGTTTCTTCATGTACAAAACTGGGGGTGCAGAGGTTGACGGGGTGACTAATGAG
GGCACACAAACCTGAAGGAGGCCCGGGCTCGGTGTGACACCTGGCTGCACCCAACATATTTAAG
TTCCTTACTTCCCTCCCCTGGCACAAAGGAGCCGAGCTGGCACAGCCAGGGGCAGTCACGGAGC
TGCGGGGGAGGCTGGCAGGGAAAGGGAAACGCTTCCCCAGCCCAGACTCTAGCTCCCTCTGGCT
GCGGGGAGCCAAGGCCCCGGCCCATTAGTCGGTCCTTCTGGACTGGAAGCAGGCTGGTCCCGTT
TGTTTCCAGGGAAAGCGGGTTAGGACTGCCTGTGGAAGGCCCCGTTGCAGGCTCCTCACAACCC
CAGTGGTAGACATTATTCCCCCCACGCAGAGGAAATGAAGGCTCCGTGAGTGACTGACACGGCG
ATAAACCAAGTCTAACTTGGCTCAAGATCTTTTCTTTGCTGGGAGGGGCTGGTGAGGCTGCAGC
AGAGGGTCCCCCAAGCTTTCTGGCCAAGCGACCTGGGTGGGTGTCCGTGACTGTACCTGCTCAG
GGCTTGCCTCTAGCTGCCTCCGAACCCTACCCTTTTCCAGGCTGGTGGCCCAGGGGATGCAGGA
ACAGCTCTAGTCTACTAAGCTGAACCCGGACTCAATGCTAACGCGTGCCCCCACCGCCTTGAGG
GTTGGGATGGGCCTGTCACTAGGCCACCTCCAAGGAAACAAATCCCTCTTCCCACTCACGTCCC
GCCGGGACATTCAGGGGCCTCAGCTTGAAGCTAGACTGGAGCAATCGCCAAGCACCGCTCCCCT
GCAAGGCAGCACATCCAGAGCGAAACAAAGAGTCAAGGGTTGTGGCTCCTGGAACCGGCATTCC
CTCTGTCCACAGCCGCCCCAGGACTCTGCTGGGCCGGGGTCGGGGCTTCCCACTAGGGGCTCCC
AAGGCTACGAGCCAAGAACCCACGCAGATGAAGGTACGGTGGGGTGCAGGGGCAGAAAGAGGAG
GGAAAATGGGCCGGCCAGAAAGCCGACTTGGAACCCTGCAGTGTCATCGCAGCCAAGTGTCTTC
ACCTCGCAGGGCCCGAGTCCTCCTCGGTAAATGAGTCCACTCGGTCCCATGGGGCGGTTGGGTA
GCTTTAACAAGCCAGTGAGCCCCGGGTCACCGCACTCTCCTCACAGGTGCCCCAACCTGGCGTC
CGTCACGCTCTCGGGCTGCGGCCACGTTACCGACGACTGCCTGGCGCGCCTGCTGCGCTGCTGC
CCACGCCTGCGCGCACTGCGCCTGGAGAACTGCGCGCGCGTCACCAACCGCACGTTGGCTGCCG
TGGCGGCGGACGGGCGCGCGCTGCAGACATTGCACGTGGACTTCTGCCGCAACGTGAGCGCGGC
CGGCCTGCGCCGCCTGCGCGCCGCGTGCCCGCGCCTGGCCCTGCGGGCAGAGCACAGCGCCGCC
ATGCTGCCCGACCAGCCCCCGCGCCCGCGCGCGCCCGCCGCGGCCCTCGGCAAGCTGCTGCAGC
GCTAGACGCCGCCCCGCCGCTGCCCCCGGGGAAGGAGCGCAGCCCCAGACCGTCCTGGCTTCGA
ACCCAGCTCTTCCACCTTCAGACCACCACCGCATATTCTGAGCCTCATTTTCCCCGTCTGCACA
GTGGGGATAAGAAAGCCTACCTCACGTTACGATTTTATACATAGGATAAACGCAAGATTAAATG
GATATTTGGAAAACA

hide sequence

RefSeq Acc Id:

NM_001367809 ⟹ NP_001354738

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	15	63,597,387 - 63,603,432 (+)	NCBI
T2T-CHM13v2.0	15	61,404,626 - 61,410,671 (+)	NCBI

Sequence:

show sequence

ACTCACATGTGGCCACTGCTCACCATGCACATAACCCAGCTCAACCGGGAGTGCCTGCTGCACC
TCTTCTCCTTCCTAGACAAGGACAGCAGGAAGAGCCTTGCCAGGACCTGCTCCCAGCTCCACGA
CGTGTTTGAGGACCCCGCACTCTGGTCCCTGCTGCACTTCCGTTCCCTCACTGAACTCCAGAAG
GACAACTTCCTCCTGGGCCCGGCACTCCGCAGCCTCTCCATCTGCTGGCACTCCAGCCGCGTGC
AGGTGTGCAGCATTGAGGACTGGCTCAAGAGTGCCTTCCAGAGAAGCATCTGCAGCCGGCACGA
GAGCCTGGTCAATGATTTCCTCCTCCGGGTGTGCGACAGGGTAAGAGGATTAAATGACACAGTG
GCACCTGGCACATAGTAGGCTTTCTGCTGTGCGCTCCCCACGGAGGCGGGAGGCGCCTGCACCG
TCCTCGGGGACTCCGATCGCCGTTGGACCGAAATCACCTCGGTGGGGAGGACCTGACCACTCGG
AGTTCGCCGACTTGCGCTCGGGGGTGACGGGGGCCAGGGCTGCCGCGCGCAGGGGTCTGGGGAG
CCTCCGGGCGGAGCGACCCAGCGAGACCCCGCCGGCTCCCGGAGTGTCCTGGGGACCGCCACCT
CCAGGAGCCCCGGTGGTGATCTCGGTGAAGCAGGAGGAGGGGAAGCAGGGGCGCACGGGCAGAA
GGAGCCACCGAGCCGCTCCTCCTTGCGGTTTTGCCCGCACGCGCGTCTGCCCGCCCACCTTTCC
TGGGGCGGATGCGTTCCCGCAGTGACCGCACTCGCGATTGTAGAAAATTCGCTCCCAATTGTTG
AATGCTTACATAAACTGCATAGTTACCCATATTTTCTACTGTTCTCATAAGGGAAAAAGAAATG
ATTTGGAAGAAAAAAAAAGCCTCAAACTAAACAAAAACAAAACCAGCAGCCCTGGCTAAGCTTT
TGATAATGGAACCATTATAAGCTGACAAGCTAGATTTTTCACCTGTTGGATTTGCTGGACATGA
GCACAAGCCTAGGCTTCCAATTTGAATTTCAGGGCTGTAGTCACTGATGTGTCACATTTAGTGA
AGGCTCTCGGCCCCCCGGCAGCCGCCTGGTCCTGGGTCACTGGGGAGAATTCTGGGTGGGTGGA
AGAGGCGAGGAGCACTGTGATGGGCGCTGTTCACACTCCGGCTCCACCCAGCGCCAGCTGCGAC
AAAGCCCTTTACCCCTCCCAGGCCAGGTGTTTCTTCTGTGTGAAAGAGGAGCTTGATCCCTACT
CACAGGTTCCTTAATTCATTGCTCAAATAGGGAAACGGCAAGGAAAAAGACAAATTCTGTTCTC
ATGAAGCTTACCTTCTAGTGGGGGAAGAGACAACAGGTAACTGGTATATAAGAGGGTAGAAGGG
CCAGGTGCGGTGGCTCAATGCCTGTAATCCCAGCACTTTAGGAGGCCAAGATGGGCGATTCACG
AGGTCAGGAGATCGAGACCATCCTGGCTAACAAGGTGAAACCCCCGTCTGTACTAAAAAAAAAT
ACAAAAAATTAGCCGGGCGTGGTGGCGGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCA
GGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCA
GCCTGGGCGACAGAGAGACTCTTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAATGGTAGAAAGT
ATTTGGAAAAAAGTGCAGGCTGTAACAAGGGCTATTAGGGATTGCTGGCAAGAGATTGGGGGGT
GAAGCCTCTGAGAAAGGGTTGACCAATGTAAGCCTCACTGAGAAGATGACATCTGAGGCATGAA
GTGAGGCAGGGGGCATAGATACTCCTGGCAGAGGAACAGTCAGTGCAGAGGCCGCGGACTACAG
GCATGGCTCATGTGCAAGGAGATCAGAGTGGCTGGAGCAGAGTGAATGAGGAGGGAAGCTGAGT
AGCAGGTATCTGAGAAGCAATGCAGCCCGCAGCTTAACTTCAACATGCTTTTAAACTTTTTTCC
CATTCTCTTGAGTTTCAAGATATAACCTTGAGGAAACTCAAAATCCTTTCTCCTTAGCCTTAAA
ATAGACTCCACGTCCCTCCCCTTTCTCACCAGATATGCTCCCTTTTCATTTATCTAACTGTATG
CTACTATTTAATTGTGTGATGTCTTAGAAGTTTCAGTGGCTAATCTTGAGACAGACCAAGCCTG
GAGACCCAGCTGCAAACCTCCAAAAATTACTTCAAAATGGCTAATTAACAACCTGACCATTGTT
AAAATAATGTCAATCCGAGGTCCAGGTGGACTGAAGCCCAAGATAGCCACCAGAACAAAACACA
CAGACATCATACTCAGCCCATTTCTTGCATGCCTTCCTTATCAAGTCTTCCCTTTTAAAAACCC
TAAAAATTGCTTTCCCCTCTAAAAATTGAAGCAGTTACTTTAAATAGCAATCTGGCTACTTCCC
CCTTTACTAGTTTTGGGTAATAAATTTGCTTTTTATTACTAGA

hide sequence

RefSeq Acc Id:

NM_203373 ⟹ NP_976307

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	15	63,597,387 - 63,603,432 (+)	NCBI
GRCh37	15	63,889,327 - 63,894,627 (+)	NCBI
Build 36	15	61,676,649 - 61,681,680 (+)	NCBI Archive
Celera	15	40,768,998 - 40,774,059 (+)	RGD
HuRef	15	40,713,981 - 40,719,056 (+)	ENTREZGENE
CHM1_1	15	64,008,778 - 64,013,853 (+)	NCBI
T2T-CHM13v2.0	15	61,404,626 - 61,410,671 (+)	NCBI

Sequence:

show sequence

ACTCACATGTGGCCACTGCTCACCATGCACATAACCCAGCTCAACCGGGAGTGCCTGCTGCACC
TCTTCTCCTTCCTAGACAAGGACAGCAGGAAGAGCCTTGCCAGGACCTGCTCCCAGCTCCACGA
CGTGTTTGAGGACCCCGCACTCTGGTCCCTGCTGCACTTCCGTTCCCTCACTGAACTCCAGAAG
GACAACTTCCTCCTGGGCCCGGCACTCCGCAGCCTCTCCATCTGCTGGCACTCCAGCCGCGTGC
AGGTGTGCAGCATTGAGGACTGGCTCAAGAGTGCCTTCCAGAGAAGCATCTGCAGCCGGCACGA
GAGCCTGGTCAATGATTTCCTCCTCCGGGTGTGCGACAGGCTTTCTGCTGTGCGCTCCCCACGG
AGGCGGGAGGCGCCTGCACCGTCCTCGGGGACTCCGATCGCCGTTGGACCGAAATCACCTCGGT
GGGGAGGACCTGACCACTCGGAGTTCGCCGACTTGCGCTCGGGGGTGACGGGGGCCAGGGCTGC
CGCGCGCAGGGGTCTGGGGAGCCTCCGGGCGGAGCGACCCAGCGAGACCCCGCCGGCTCCCGGA
GTGTCCTGGGGACCGCCACCTCCAGGAGCCCCGGTGGTGATCTCGGTGAAGCAGGAGGAGGGGA
AGCAGGGGCGCACGGGCAGAAGGAGCCACCGAGCCGCTCCTCCTTGCGGTTTTGCCCGCACGCG
CGTCTGCCCGCCCACCTTTCCTGGGGCGGATGCGTTCCCGCAGTGACCGCACTCGCGATTGTAG
AAAATTCGCTCCCAATTGTTGAATGCTTACATAAACTGCATAGTTACCCATATTTTCTACTGTT
CTCATAAGGGAAAAAGAAATGATTTGGAAGAAAAAAAAAGCCTCAAACTAAACAAAAACAAAAC
CAGCAGCCCTGGCTAAGCTTTTGATAATGGAACCATTATAAGCTGACAAGCTAGATTTTTCACC
TGTTGGATTTGCTGGACATGAGCACAAGCCTAGGCTTCCAATTTGAATTTCAGGGCTGTAGTCA
CTGATGTGTCACATTTAGTGAAGGCTCTCGGCCCCCCGGCAGCCGCCTGGTCCTGGGTCACTGG
GGAGAATTCTGGGTGGGTGGAAGAGGCGAGGAGCACTGTGATGGGCGCTGTTCACACTCCGGCT
CCACCCAGCGCCAGCTGCGACAAAGCCCTTTACCCCTCCCAGGCCAGGTGTTTCTTCTGTGTGA
AAGAGGAGCTTGATCCCTACTCACAGGTTCCTTAATTCATTGCTCAAATAGGGAAACGGCAAGG
AAAAAGACAAATTCTGTTCTCATGAAGCTTACCTTCTAGTGGGGGAAGAGACAACAGGTAACTG
GTATATAAGAGGGTAGAAGGGCCAGGTGCGGTGGCTCAATGCCTGTAATCCCAGCACTTTAGGA
GGCCAAGATGGGCGATTCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACAAGGTGAAACCC
CCGTCTGTACTAAAAAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGCACCTGTAGTCCCA
GCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCA
AGATCGTGCCACTGCACTCCAGCCTGGGCGACAGAGAGACTCTTGTCTCAAAAAAAAAAAAAAA
AAAAAAAAAATGGTAGAAAGTATTTGGAAAAAAGTGCAGGCTGTAACAAGGGCTATTAGGGATT
GCTGGCAAGAGATTGGGGGGTGAAGCCTCTGAGAAAGGGTTGACCAATGTAAGCCTCACTGAGA
AGATGACATCTGAGGCATGAAGTGAGGCAGGGGGCATAGATACTCCTGGCAGAGGAACAGTCAG
TGCAGAGGCCGCGGACTACAGGCATGGCTCATGTGCAAGGAGATCAGAGTGGCTGGAGCAGAGT
GAATGAGGAGGGAAGCTGAGTAGCAGGTATCTGAGAAGCAATGCAGCCCGCAGCTTAACTTCAA
CATGCTTTTAAACTTTTTTCCCATTCTCTTGAGTTTCAAGATATAACCTTGAGGAAACTCAAAA
TCCTTTCTCCTTAGCCTTAAAATAGACTCCACGTCCCTCCCCTTTCTCACCAGATATGCTCCCT
TTTCATTTATCTAACTGTATGCTACTATTTAATTGTGTGATGTCTTAGAAGTTTCAGTGGCTAA
TCTTGAGACAGACCAAGCCTGGAGACCCAGCTGCAAACCTCCAAAAATTACTTCAAAATGGCTA
ATTAACAACCTGACCATTGTTAAAATAATGTCAATCCGAGGTCCAGGTGGACTGAAGCCCAAGA
TAGCCACCAGAACAAAACACACAGACATCATACTCAGCCCATTTCTTGCATGCCTTCCTTATCA
AGTCTTCCCTTTTAAAAACCCTAAAAATTGCTTTCCCCTCTAAAAATTGAAGCAGTTACTTTAA
ATAGCAATCTGGCTACTTCCCCCTTTACTAGTTTTGGGTAATAAATTTGCTTTTTATTACTAGA

hide sequence

RefSeq Acc Id:

XM_047432400 ⟹ XP_047288356

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	15	63,597,387 - 63,608,516 (+)	NCBI

RefSeq Acc Id:

XM_054377749 ⟹ XP_054233724

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	15	61,404,626 - 61,415,756 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001354736	(Get FASTA)	NCBI Sequence Viewer
	NP_001354737	(Get FASTA)	NCBI Sequence Viewer
	NP_001354738	(Get FASTA)	NCBI Sequence Viewer
	NP_976307	(Get FASTA)	NCBI Sequence Viewer
	XP_047288356	(Get FASTA)	NCBI Sequence Viewer
	XP_054233724	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH65833	(Get FASTA)	NCBI Sequence Viewer
	EAW77653	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000353794
	ENSP00000353794.3
	ENSP00000453697
	ENSP00000453697.2
	ENSP00000473666.1
	ENSP00000492359
	ENSP00000492359.1
GenBank Protein	Q6P050	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_976307 ⟸ NM_203373
- Peptide Label:	isoform 1
- UniProtKB:	Q6P050 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MWPLLTMHITQLNRECLLHLFSFLDKDSRKSLARTCSQLHDVFEDPALWSLLHFRSLTELQKDN FLLGPALRSLSICWHSSRVQVCSIEDWLKSAFQRSICSRHESLVNDFLLRVCDRLSAVRSPRRR EAPAPSSGTPIAVGPKSPRWGGPDHSEFADLRSGVTGARAAARRGLGSLRAERPSETPPAPGVS WGPPPPGAPVVISVKQEEGKQGRTGRRSHRAAPPCGFARTRVCPPTFPGADAFPQ hide sequence

RefSeq Acc Id:	NP_001354738 ⟸ NM_001367809
- Peptide Label:	isoform 3
- UniProtKB:	H0YMQ4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001354737 ⟸ NM_001367808
- Peptide Label:	isoform 3
- UniProtKB:	H0YMQ4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001354736 ⟸ NM_001367807
- Peptide Label:	isoform 2
- UniProtKB:	A0A1W2PQW8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSP00000492359 ⟸ ENST00000638704

RefSeq Acc Id:

ENSP00000353794 ⟸ ENST00000360587

RefSeq Acc Id:

ENSP00000453697 ⟸ ENST00000534939

RefSeq Acc Id:

ENSP00000473666 ⟸ ENST00000560325

RefSeq Acc Id:	XP_047288356 ⟸ XM_047432400
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_054233724 ⟸ XM_054377749
- Peptide Label:	isoform X1

Protein Domains

F-box

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6P050-F1-model_v2	AlphaFold	Q6P050	1-247	view protein structure

Promoters

RGD ID:

6792334

Promoter ID:

HG_KWN:21629

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, Lymphoblastoid

Transcripts:

OTTHUMT00000256412, UC002AMM.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	15	61,675,656 - 61,676,947 (+)	MPROMDB

RGD ID:

7229745

Promoter ID:

EPDNEW_H20618

Type:

initiation region

Name:

FBXL22_1

Description:

F-box and leucine rich repeat protein 22

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	15	63,597,387 - 63,597,447	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:27537	AgrOrtholog
COSMIC	FBXL22	COSMIC
Ensembl Genes	ENSG00000197361	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENST00000360587	ENTREZGENE
	ENST00000360587.2	UniProtKB/Swiss-Prot
	ENST00000534939	ENTREZGENE
	ENST00000534939.2	UniProtKB/TrEMBL
	ENST00000560325.1	UniProtKB/TrEMBL
	ENST00000638704	ENTREZGENE
	ENST00000638704.2	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1280.50	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.80.10.10	UniProtKB/TrEMBL
GTEx	ENSG00000197361	GTEx
HGNC ID	HGNC:27537	ENTREZGENE
Human Proteome Map	FBXL22	Human Proteome Map
InterPro	F-box-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	F-box_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	L_dom-like	UniProtKB/TrEMBL
	Leu-rich_rpt_Cys-con_subtyp	UniProtKB/TrEMBL
KEGG Report	hsa:283807	UniProtKB/Swiss-Prot
NCBI Gene	283807	ENTREZGENE
OMIM	609088	OMIM
PANTHER	F-BOX AND LEUCINE-RICH PROTEIN 22	UniProtKB/TrEMBL
	F-BOX/TPR REPEAT PROTEIN POF3	UniProtKB/TrEMBL
Pfam	F-box-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA134959373	PharmGKB
SMART	LRR_CC	UniProtKB/TrEMBL
Superfamily-SCOP	RNI-like	UniProtKB/TrEMBL
	SSF81383	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A1W2PQW8	ENTREZGENE, UniProtKB/TrEMBL
	FXL22_HUMAN	UniProtKB/Swiss-Prot
	H0YMQ4	ENTREZGENE, UniProtKB/TrEMBL
	Q6P050	ENTREZGENE
	R4GNI3_HUMAN	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-06-14	FBXL22	F-box and leucine rich repeat protein 22		F-box and leucine-rich repeat protein 22	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Human Phenotype Annotations - ClinVar

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Imported Disease Annotations - ClinVar

Imported Human Phenotype Annotations - ClinVar