RNF26 (ring finger protein 26) - Rat Genome Database

Name: RNF26
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Advanced Search (OLGA)

Gene: RNF26 (ring finger protein 26) Homo sapiens

Analyze

Symbol:

RNF26

Name:

ring finger protein 26

RGD ID:

1314288

HGNC Page

HGNC:14646

Description:

Enables ubiquitin protein ligase activity. Involved in several processes, including negative regulation of defense response to virus; protein K11-linked ubiquitination; and protein localization to perinuclear region of cytoplasm. Is active in endoplasmic reticulum membrane.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

E3 ubiquitin-protein ligase RNF26; MGC2642; ring finger protein with leucine zipper

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Rnf26 (ring finger protein 26)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Rnf26 (ring finger protein 26)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Chinchilla lanigera (long-tailed chinchilla):	Rnf26 (ring finger protein 26)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	RNF26 (ring finger protein 26)	NCBI	Ortholog
Canis lupus familiaris (dog):	RNF26 (ring finger protein 26)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnf26 (ring finger protein 26)	NCBI	Ortholog
Sus scrofa (pig):	RNF26 (ring finger protein 26)	HGNC	EggNOG, Ensembl, NCBI, OMA, OrthoDB, Panther, Treefam
Chlorocebus sabaeus (green monkey):	RNF26 (ring finger protein 26)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Rnf26 (ring finger protein 26)	NCBI	Ortholog
Other homologs ²
Mus musculus (house mouse):	Rnf26rt (ring finger protein 26, retrotransposed)	HGNC	EggNOG, Ensembl, Inparanoid, OrthoMCL, Panther, Treefam
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Rnf26 (ring finger protein 26)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rnf26 (ring finger protein 26)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rnf26rt (ring finger protein 26, retrotransposed)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rnf26 (ring finger protein 26)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Caenorhabditis elegans (roundworm):	C56A3.4	Alliance	DIOPT (Ensembl Compara\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG2617	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector)
Xenopus tropicalis (tropical clawed frog):	rnf26	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus laevis (African clawed frog):	rnf26.L	Alliance	DIOPT (Xenbase)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	119,334,527 - 119,337,309 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	119,334,527 - 119,337,309 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	119,205,237 - 119,208,019 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	118,710,447 - 118,713,232 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	118,710,446 - 118,713,231	NCBI
Celera	11	116,365,908 - 116,368,693 (+)	NCBI		Celera
Cytogenetic Map	11	q23.3	NCBI
HuRef	11	115,145,909 - 115,148,723 (+)	NCBI		HuRef
CHM1_1	11	119,091,769 - 119,094,583 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	119,355,164 - 119,357,946 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

CD3epsilon deficiency (IAGP)

chromosome 11 partial duplication syndrome (IAGP)

Dwarfism (IAGP)

immunodeficiency 17 (IAGP)

immunodeficiency 18 (IAGP)

immunodeficiency 19 (IAGP)

inflammatory bowel disease 28 (IAGP)

isolated microphthalmia 5 (IAGP)

RASopathy (IAGP)

schizophrenia (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (EXP)

4,4'-diaminodiphenylmethane (ISO)

acetylsalicylic acid (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

amphetamine (ISO)

aristolochic acid A (EXP)

atrazine (EXP)

benzo[a]pyrene (EXP)

benzo[a]pyrene diol epoxide I (EXP)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

buspirone (ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

CGP 52608 (EXP)

chromium(6+) (EXP)

cisplatin (EXP)

cobalt dichloride (ISO)

copper(II) sulfate (EXP)

coumestrol (EXP)

cyclosporin A (EXP)

dexamethasone (EXP)

dicrotophos (EXP)

Enterolactone (EXP)

epoxiconazole (ISO)

ethanol (ISO)

hydrogen peroxide (EXP)

hypochlorous acid (ISO)

indometacin (EXP)

leflunomide (EXP)

methyl methanesulfonate (EXP)

nimesulide (ISO)

nitrofen (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

potassium chromate (EXP)

resveratrol (EXP)

sodium arsenite (EXP)

sulindac (EXP)

thioacetamide (ISO)

thiram (EXP)

trichloroethene (ISO)

trimellitic anhydride (ISO)

troglitazone (ISO)

trovafloxacin (ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endosome organization (IDA)

negative regulation of defense response to virus (IDA)

protein K11-linked ubiquitination (IDA)

protein localization to perinuclear region of cytoplasm (IDA)

protein ubiquitination (IBA,IDA,IEA)

regulation of type I interferon production (IDA)

ubiquitin-dependent protein catabolic process (IBA)

Cellular Component

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IDA,IEA)

membrane (IEA)

Molecular Function

metal ion binding (IEA)

protein binding (IPI)

transferase activity (IEA)

ubiquitin protein ligase activity (IBA,IDA)

zinc ion binding (NAS)

Phenotype Annotations Click to see Annotation Detail View

Human Phenotype

Schizophrenia (IAGP)

Short stature (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11352657	PMID:12477932	PMID:14702039	PMID:15489334	PMID:16303743	PMID:18187620	PMID:18976975	PMID:19549727	PMID:19690564	PMID:19913121	PMID:20628086	PMID:21750715
PMID:21873635	PMID:25254379	PMID:26186194	PMID:27368102	PMID:28514442	PMID:28786561	PMID:30759391	PMID:32614325	PMID:33087821	PMID:33472082	PMID:33961781	PMID:35281267
PMID:36224200	PMID:37519262

Genomics

Comparative Map Data

RNF26
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	119,334,527 - 119,337,309 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	119,334,527 - 119,337,309 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	119,205,237 - 119,208,019 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	118,710,447 - 118,713,232 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	118,710,446 - 118,713,231	NCBI
Celera	11	116,365,908 - 116,368,693 (+)	NCBI		Celera
Cytogenetic Map	11	q23.3	NCBI
HuRef	11	115,145,909 - 115,148,723 (+)	NCBI		HuRef
CHM1_1	11	119,091,769 - 119,094,583 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	119,355,164 - 119,357,946 (+)	NCBI		T2T-CHM13v2.0

Rnf26
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	44,022,078 - 44,024,348 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	43,977,624 - 44,024,797 (-)	Ensembl		GRCm39 Ensembl
GRCm39 Ensembl	9	44,006,928 - 44,024,814 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	44,110,781 - 44,113,051 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	44,095,631 - 44,113,517 (-)	Ensembl	GRCm38		mm10	GRCm38
GRCm38.p6 Ensembl	9	44,066,327 - 44,113,500 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	43,918,864 - 43,921,134 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	43,861,776 - 43,864,046 (-)	NCBI		MGSCv36	mm8
Celera	6	78,512,145 - 78,514,433 (-)	NCBI		Celera
Cytogenetic Map	9	A5.1	NCBI
cM Map	9	24.53	NCBI

Rnf26
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	53,351,388 - 53,353,586 (-)	NCBI		GRCr8
mRatBN7.2	8	44,454,551 - 44,456,745 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	44,454,292 - 44,457,331 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	49,952,792 - 49,954,990 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	48,231,502 - 48,233,700 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	46,099,121 - 46,101,309 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	48,447,113 - 48,449,311 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	48,447,113 - 48,449,311 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	47,062,942 - 47,065,140 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	47,092,910 - 47,095,108 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	47,102,330 - 47,104,426 (-)	NCBI
Celera	8	44,041,748 - 44,043,946 (-)	NCBI		Celera
Cytogenetic Map	8	q22	NCBI

Rnf26
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	20,416,067 - 20,417,368 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	20,415,468 - 20,418,263 (+)	NCBI	ChiLan1.0	ChiLan1.0

RNF26
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	120,042,260 - 120,045,069 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	121,145,774 - 121,148,583 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	114,175,586 - 114,178,379 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	118,102,883 - 118,105,698 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	118,103,505 - 118,104,806 (+)	Ensembl	panpan1.1		panPan2

RNF26
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	14,564,949 - 14,567,756 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	14,618,431 - 14,621,237 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	14,508,302 - 14,511,107 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	5	14,646,590 - 14,649,394 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	14,550,582 - 14,553,387 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	14,590,708 - 14,593,515 (-)	NCBI		UU_Cfam_GSD_1.0

Rnf26
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	101,343,833 - 101,346,628 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936542	4,265,226 - 4,268,037 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNF26
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	46,543,735 - 46,546,569 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	46,543,732 - 46,546,570 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	51,577,978 - 51,580,815 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RNF26
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	110,713,453 - 110,716,281 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	110,714,081 - 110,715,379 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	15,318,719 - 15,321,545 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnf26
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624784	14,703,369 - 14,706,194 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in RNF26
29 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 11q23.3-25(chr11:116851395-134998513)x3	copy number gain	See cases [RCV000050331]	Chr11:116851395..134998513 [GRCh38] Chr11:116722111..134868407 [GRCh37] Chr11:116227321..134373617 [NCBI36] Chr11:11q23.3-25	pathogenic
GRCh38/hg38 11q23.2-23.3(chr11:113444446-120648921)x3	copy number gain	See cases [RCV000050627]	Chr11:113444446..120648921 [GRCh38] Chr11:113315168..120519630 [GRCh37] Chr11:112820378..120024840 [NCBI36] Chr11:11q23.2-23.3	pathogenic
GRCh38/hg38 11q23.3-25(chr11:118789765-134998513)x3	copy number gain	See cases [RCV000051213]	Chr11:118789765..134998513 [GRCh38] Chr11:118660474..134868407 [GRCh37] Chr11:118165684..134373617 [NCBI36] Chr11:11q23.3-25	pathogenic
GRCh38/hg38 11q23.3-25(chr11:119215032-134998654)x1	copy number loss	See cases [RCV000052715]	Chr11:119215032..134998654 [GRCh38] Chr11:119085742..134868548 [GRCh37] Chr11:118590952..134373758 [NCBI36] Chr11:11q23.3-25	pathogenic
GRCh38/hg38 11q22.1-25(chr11:100348599-135040246)x3	copy number gain	See cases [RCV000053638]	Chr11:100348599..135040246 [GRCh38] Chr11:100219331..134910140 [GRCh37] Chr11:99724541..134415350 [NCBI36] Chr11:11q22.1-25	pathogenic
NM_032015.4(RNF26):c.985C>T (p.Pro329Ser)	single nucleotide variant	Malignant melanoma [RCV000069190]	Chr11:119336107 [GRCh38] Chr11:119206817 [GRCh37] Chr11:118712027 [NCBI36] Chr11:11q23.3	not provided
GRCh38/hg38 11q23.3-25(chr11:116851372-134998526)x3	copy number gain	See cases [RCV000134064]	Chr11:116851372..134998526 [GRCh38] Chr11:116722088..134868420 [GRCh37] Chr11:116227298..134373630 [NCBI36] Chr11:11q23.3-25	pathogenic
GRCh38/hg38 11q23.2-25(chr11:112864326-131189315)x3	copy number gain	See cases [RCV000137582]	Chr11:112864326..131189315 [GRCh38] Chr11:112832130..131059210 [GRCh37] Chr11:112240259..130564420 [NCBI36] Chr11:11q23.2-25	pathogenic
GRCh38/hg38 11q23.3-25(chr11:116868935-135075271)x3	copy number gain	See cases [RCV000137453]	Chr11:116868935..135075271 [GRCh38] Chr11:116739651..134945165 [GRCh37] Chr11:116244861..134450377 [NCBI36] Chr11:11q23.3-25	pathogenic\|conflicting data from submitters
GRCh38/hg38 11q23.3-25(chr11:116806268-135075271)x3	copy number gain	See cases [RCV000138307]	Chr11:116806268..135075271 [GRCh38] Chr11:116676984..134945165 [GRCh37] Chr11:116182194..134450377 [NCBI36] Chr11:11q23.3-25	pathogenic
GRCh38/hg38 11q23.3-24.2(chr11:117333952-127709156)x3	copy number gain	See cases [RCV000139362]	Chr11:117333952..127709156 [GRCh38] Chr11:117204668..127579051 [GRCh37] Chr11:116709878..127084261 [NCBI36] Chr11:11q23.3-24.2	pathogenic
GRCh38/hg38 11q23.3-25(chr11:116851395-134998513)x3	copy number gain	See cases [RCV000148276]	Chr11:116851395..134998513 [GRCh38] Chr11:116722111..134868407 [GRCh37] Chr11:116227321..134373617 [NCBI36] Chr11:11q23.3-25	pathogenic
GRCh37/hg19 11q23.3(chr11:115215434-120559928)x3	copy number gain	See cases [RCV000240308]	Chr11:115215434..120559928 [GRCh37] Chr11:11q23.3	pathogenic
GRCh37/hg19 11q23.3-25(chr11:116700253-134904063)	copy number gain	not provided [RCV000767816]	Chr11:116700253..134904063 [GRCh37] Chr11:11q23.3-25	pathogenic
GRCh37/hg19 11q23.3-25(chr11:116681007-134938470)x3	copy number gain	See cases [RCV000449449]	Chr11:116681007..134938470 [GRCh37] Chr11:11q23.3-25	pathogenic
GRCh37/hg19 11q23.3-25(chr11:116684163-134938470)x3	copy number gain	See cases [RCV000447848]	Chr11:116684163..134938470 [GRCh37] Chr11:11q23.3-25	pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)	copy number gain	See cases [RCV000511729]	Chr11:230616..134938470 [GRCh37] Chr11:11p15.5-q25	pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3	copy number gain	See cases [RCV000510881]	Chr11:230616..134938470 [GRCh37] Chr11:11p15.5-q25	pathogenic
GRCh37/hg19 11q23.3-25(chr11:116681007-134938470)x3	copy number gain	See cases [RCV000512291]	Chr11:116681007..134938470 [GRCh37] Chr11:11q23.3-25	pathogenic
GRCh37/hg19 11q23.3-25(chr11:116681007-134938470)x3	copy number gain	not provided [RCV000683373]	Chr11:116681007..134938470 [GRCh37] Chr11:11q23.3-25	pathogenic
GRCh37/hg19 11q23.3(chr11:116669751-120979377)x3	copy number gain	not provided [RCV000683365]	Chr11:116669751..120979377 [GRCh37] Chr11:11q23.3	likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3	copy number gain	not provided [RCV000737348]	Chr11:198510..134934063 [GRCh37] Chr11:11p15.5-q25	pathogenic
Single allele	duplication	Schizophrenia [RCV000754124]	Chr11:118989374..135076622 [GRCh38] Chr11:11q23.3-25	likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3	copy number gain	not provided [RCV000749874]	Chr11:70864..134938470 [GRCh37] Chr11:11p15.5-q25	pathogenic
GRCh37/hg19 11q23.3-25(chr11:116697066-134934063)x3	copy number gain	not provided [RCV000737686]	Chr11:116697066..134934063 [GRCh37] Chr11:11q23.3-25	pathogenic
GRCh37/hg19 11q23.3-25(chr11:116691675-134889485)	copy number gain	not provided [RCV000767667]	Chr11:116691675..134889485 [GRCh37] Chr11:11q23.3-25	pathogenic
GRCh37/hg19 11q23.3-25(chr11:117830263-134938470)x3	copy number gain	not provided [RCV000848151]	Chr11:117830263..134938470 [GRCh37] Chr11:11q23.3-25	pathogenic
GRCh37/hg19 11q23.3(chr11:118280670-119650105)x3	copy number gain	not provided [RCV001006451]	Chr11:118280670..119650105 [GRCh37] Chr11:11q23.3	uncertain significance
Single allele	deletion	Short stature [RCV001003892]	Chr11:114433313..131230466 [GRCh37] Chr11:11q23.2-25	likely pathogenic
NC_000011.9:g.(?_119077108)_(120133495_?)dup	duplication	RASopathy [RCV001314250]	Chr11:119077108..120133495 [GRCh37] Chr11:11q23.3	uncertain significance
NC_000011.9:g.104288964_134937416dup	duplication	Distal trisomy 11q [RCV001250234]	Chr11:104288964..134937416 [GRCh37] Chr11:11q22.3-25	pathogenic
NC_000011.9:g.(?_116691583)_(121500272_?)dup	duplication	Combined immunodeficiency due to CD3gamma deficiency [RCV003119252]\|Immunodeficiency 18 [RCV003109226]\|Immunodeficiency 19 [RCV003109224]\|Inflammatory bowel disease 28 [RCV003109225]\|Isolated microphthalmia 5 [RCV003119251]\|RASopathy [RCV003119250]	Chr11:116691583..121500272 [GRCh37] Chr11:11q23.3-24.1	uncertain significance
GRCh37/hg19 11q23.1-24.3(chr11:112375478-128785742)x3	copy number gain	not provided [RCV001829187]	Chr11:112375478..128785742 [GRCh37] Chr11:11q23.1-24.3	pathogenic
NC_000011.9:g.(?_116660844)_(121500272_?)dup	duplication	not provided [RCV003107886]	Chr11:116660844..121500272 [GRCh37] Chr11:11q23.3-24.1	uncertain significance
NC_000011.9:g.(?_119103138)_(121060609_?)dup	duplication	not provided [RCV003116365]	Chr11:119103138..121060609 [GRCh37] Chr11:11q23.3	uncertain significance
NC_000011.9:g.(?_117209303)_(120133495_?)dup	duplication	not provided [RCV003122151]	Chr11:117209303..120133495 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.392G>A (p.Arg131His)	single nucleotide variant	not specified [RCV004294177]	Chr11:119335514 [GRCh38] Chr11:119206224 [GRCh37] Chr11:11q23.3	uncertain significance
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3	copy number gain	MISSED ABORTION [RCV002282973]	Chr11:32799481..134938470 [GRCh37] Chr11:11p13-q25	pathogenic
NM_032015.5(RNF26):c.968G>A (p.Arg323Gln)	single nucleotide variant	not specified [RCV004195087]	Chr11:119336090 [GRCh38] Chr11:119206800 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.434C>T (p.Ala145Val)	single nucleotide variant	not specified [RCV004092482]	Chr11:119335556 [GRCh38] Chr11:119206266 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.887A>G (p.Gln296Arg)	single nucleotide variant	not specified [RCV004170231]	Chr11:119336009 [GRCh38] Chr11:119206719 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.97C>G (p.Leu33Val)	single nucleotide variant	not specified [RCV004114530]	Chr11:119335219 [GRCh38] Chr11:119205929 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.523G>A (p.Gly175Arg)	single nucleotide variant	not specified [RCV004075989]	Chr11:119335645 [GRCh38] Chr11:119206355 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.719T>C (p.Val240Ala)	single nucleotide variant	not specified [RCV004234948]	Chr11:119335841 [GRCh38] Chr11:119206551 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.574T>G (p.Ser192Ala)	single nucleotide variant	not specified [RCV004243945]	Chr11:119335696 [GRCh38] Chr11:119206406 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.375T>G (p.Ser125Arg)	single nucleotide variant	not specified [RCV004245556]	Chr11:119335497 [GRCh38] Chr11:119206207 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.1265G>A (p.Arg422His)	single nucleotide variant	not specified [RCV004150320]	Chr11:119336387 [GRCh38] Chr11:119207097 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.956C>T (p.Ser319Leu)	single nucleotide variant	not specified [RCV004231760]	Chr11:119336078 [GRCh38] Chr11:119206788 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.1187G>A (p.Arg396Gln)	single nucleotide variant	not specified [RCV004168461]	Chr11:119336309 [GRCh38] Chr11:119207019 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.778C>G (p.Gln260Glu)	single nucleotide variant	not specified [RCV004166813]	Chr11:119335900 [GRCh38] Chr11:119206610 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.155C>T (p.Thr52Ile)	single nucleotide variant	not specified [RCV004149409]	Chr11:119335277 [GRCh38] Chr11:119205987 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.791G>A (p.Arg264Gln)	single nucleotide variant	not specified [RCV004289706]	Chr11:119335913 [GRCh38] Chr11:119206623 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.835C>T (p.Arg279Cys)	single nucleotide variant	not specified [RCV004254168]	Chr11:119335957 [GRCh38] Chr11:119206667 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.1082C>T (p.Pro361Leu)	single nucleotide variant	not specified [RCV004272300]	Chr11:119336204 [GRCh38] Chr11:119206914 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.472G>A (p.Gly158Ser)	single nucleotide variant	not specified [RCV004248640]	Chr11:119335594 [GRCh38] Chr11:119206304 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.790C>T (p.Arg264Trp)	single nucleotide variant	not specified [RCV004290880]	Chr11:119335912 [GRCh38] Chr11:119206622 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.764C>G (p.Thr255Ser)	single nucleotide variant	not specified [RCV004348927]	Chr11:119335886 [GRCh38] Chr11:119206596 [GRCh37] Chr11:11q23.3	uncertain significance
Single allele	duplication	not provided [RCV003448710]	Chr11:102134973..134945611 [GRCh37] Chr11:11q22.2-25	pathogenic
GRCh37/hg19 11q23.3-25(chr11:116683755-134937416)x3	copy number gain	not provided [RCV004442759]	Chr11:116683755..134937416 [GRCh37] Chr11:11q23.3-25	pathogenic
NM_032015.5(RNF26):c.232G>C (p.Gly78Arg)	single nucleotide variant	not specified [RCV004446721]	Chr11:119335354 [GRCh38] Chr11:119206064 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.577A>G (p.Ser193Gly)	single nucleotide variant	not specified [RCV004446722]	Chr11:119335699 [GRCh38] Chr11:119206409 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.907C>T (p.Arg303Trp)	single nucleotide variant	not specified [RCV004446724]	Chr11:119336029 [GRCh38] Chr11:119206739 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.1045C>A (p.Pro349Thr)	single nucleotide variant	not specified [RCV004446720]	Chr11:119336167 [GRCh38] Chr11:119206877 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.697T>A (p.Leu233Met)	single nucleotide variant	not specified [RCV004446723]	Chr11:119335819 [GRCh38] Chr11:119206529 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.947G>A (p.Arg316Lys)	single nucleotide variant	not specified [RCV004665505]	Chr11:119336069 [GRCh38] Chr11:119206779 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.221G>C (p.Arg74Pro)	single nucleotide variant	not specified [RCV004665508]	Chr11:119335343 [GRCh38] Chr11:119206053 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.948G>T (p.Arg316Ser)	single nucleotide variant	not specified [RCV004665506]	Chr11:119336070 [GRCh38] Chr11:119206780 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.1045C>T (p.Pro349Ser)	single nucleotide variant	not specified [RCV004665507]	Chr11:119336167 [GRCh38] Chr11:119206877 [GRCh37] Chr11:11q23.3	uncertain significance
NM_032015.5(RNF26):c.70C>A (p.Leu24Ile)	single nucleotide variant	not specified [RCV004665509]	Chr11:119335192 [GRCh38] Chr11:119205902 [GRCh37] Chr11:11q23.3	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	590
Count of miRNA genes:	431
Interacting mature miRNAs:	477
Transcripts:	ENST00000311413
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCh38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
407314133	GWAS963109_H	platelet count QTL GWAS963109 (human)		5e-25	platelet quantity (VT:0003179)	platelet count (CMO:0000029)	11	119337218	119337219	Human
406893876	GWAS542852_H	complement C1q tumor necrosis factor-related protein 5 measurement QTL GWAS542852 (human)		4e-21	complement C1q tumor necrosis factor-related protein 5 measurement		11	119336631	119336632	Human
1559115	SCL20_H	Serum cholesterol level QTL 20 (human)	3.22	0.001213	Lipid level	LDL cholesterol	11	100442501	126442501	Human
407199562	GWAS848538_H	blood protein measurement QTL GWAS848538 (human)		2e-27	blood protein measurement	blood protein measurement (CMO:0000028)	11	119336736	119336737	Human

Markers in Region

A005D38

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	11	119,207,802 - 119,208,018	UniSTS	GRCh37
Build 36	11	118,713,012 - 118,713,228	RGD	NCBI36
Celera	11	116,368,473 - 116,368,689	RGD
Cytogenetic Map	11	q23	UniSTS
HuRef	11	115,148,501 - 115,148,717	UniSTS
GeneMap99-GB4 RH Map	11	386.42	UniSTS
Whitehead-RH Map	11	533.4	UniSTS

Bdaa7g02

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	11	119,207,869 - 119,207,972	UniSTS	GRCh37
Build 36	11	118,713,079 - 118,713,182	RGD	NCBI36
Celera	11	116,368,540 - 116,368,643	RGD
Cytogenetic Map	11	q23	UniSTS
HuRef	11	115,148,568 - 115,148,671	UniSTS
GeneMap99-GB4 RH Map	11	386.52	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system	visual system
1204	2439	2788	2253	4974	1726	2351	6	624	1950	465	2270	7305	6471	53	3734	1	852	1744	1617	175	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_032015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB055622	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK075379	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK122642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL702838	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AP003396	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC000058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC007534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BQ953192	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX647424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX648447	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK821090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068267	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CS051427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000311413 ⟹ ENSP00000312439

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	11	119,334,527 - 119,337,309 (+)	Ensembl

RefSeq Acc Id:

NM_032015 ⟹ NP_114404

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	11	119,334,527 - 119,337,309 (+)	NCBI
GRCh37	11	119,205,210 - 119,208,024 (+)	NCBI
Build 36	11	118,710,447 - 118,713,232 (+)	NCBI Archive
Celera	11	116,365,908 - 116,368,693 (+)	RGD
HuRef	11	115,145,909 - 115,148,723 (+)	NCBI
CHM1_1	11	119,091,769 - 119,094,583 (+)	NCBI
T2T-CHM13v2.0	11	119,355,164 - 119,357,946 (+)	NCBI

Sequence:

show sequence

ACACAAGATGGCGGCGCCCAGCGGAGTAGGGGCTGCGCTTGGGGTTTGCTGAAGCTGGCTGCCT
CTCCCACTCCCCTTTTGGGTGCAAAGCGCCGCTAGCGGGAAGACGGGGGCCGGGCGGGGACAGG
GGCACCTGCGTAGCTGGACTGAGAGCCTGCGCCCAGCTTACATCGACCCCACCCGGCCCCGGCC
CGACCCGACGCGACCCGATCCGATCCGATCCCATTCCATCCGTTCCTCGTCTCCTCCCGGTCTG
ACCCGTTGCCCGGCCGTGGTTCGCCACACCAGGCATCCAAAGCTGAGGTCGCTCCTACGGCCTG
GGCTCGCCTTCGCTTTAGAGATGTTTGGCCTCTTCCCTCCCAAACAGCCCATCTTCAAAACCTG
GACTCTTGGACTGGCACCTGGCCACCTTTCCCTCTACCAAGACTCCACTTCCGTCTTACCCACT
TCTTCCTCAGATTCTTGGTACCCCCTGGGTTGGAGACTGCTCATTTTCCTTCCAAATTAATCCC
AGACCCCCTAAAATATTGACAACCTTGACAACCCCCCAACCGAGGAGCCAGACTTTGTTTTGGA
CTAACTTCCATAGCCCTATCATGGAGGCAGTGTACCTGGTAGTGAATGGGTTGGGCCTGGTGCT
GGACGTGCTGACCTTGGTGTTGGACCTCAACTTCCTGCTGGTGTCCTCCCTCCTGGCTTCCCTG
GCCTGGCTCCTGGCCTTCGTCTACAACCTGCCGCACACGGTACTGACTAGTCTTCTGCACTTGG
GCCGCGGAGTCTTGCTTTCATTGCTGGCCTTGATCGAAGCCGTGGTCCGGTTCACATGTGGGGG
CTTGCAGGCCTTGTGTACTCTGCTGTATAGCTGCTGCTCTGGCCTAGAGAGCCTAAAGCTCCTG
GGGCACCTGGCCTCTCATGGGGCACTGCGGAGCAGGGAGATACTGCACCGGGGCGTCCTCAATG
TGGTCTCCAGTGGCCATGCTTTGCTGCGCCAGGCCTGTGACATCTGTGCCATTGCCATGAGCCT
GGTGGCTTATGTGATCAACAGCCTGGTCAACATCTGCCTCATCGGCACTCAGAACCTCTTTTCC
CTGGTGCTGGCCCTGTGGGATGCAGTGACCGGGCCTCTGTGGAGGATGACGGACGTAGTGGCTG
CCTTCCTAGCCCACATTTCCAGCAGTGCTGTGGCCATGGCCATCCTCCTTTGGACACCCTGCCA
ACTAGCCCTGGAGCTGCTGGCCTCAGCTGCCCGCCTCCTGGCCAGCTTTGTGCTTGTCAATCTC
ACTGGCTTGGTGTTGCTAGCTTGTGTGCTGGCAGTGACGGTGACTGTGTTGCATCCGGACTTCA
CCCTGAGGCTGGCTACCCAGGCACTCAGCCAGCTCCATGCCCGGCCATCCTACCACCGTCTTCG
AGAGGATGTCATGCGGCTCTCTCGCCTAGCACTGGGCTCAGAGGCCTGGCGCCGAGTCTGGAGC
CGCAGTCTGCAGCTGGCGAGTTGGCCAAACCGGGGAGGGGCACCTGGAGCTCCCCAGGGTGACC
CTATGAGGGTATTCTCAGTTAGGACCCGGAGACAGGACACTCTTCCTGAAGCGGGGCGCAGATC
AGAGGCAGAAGAGGAGGAGGCCAGGACCATCAGAGTGACACCTGTCAGGGGCCGAGAGAGGCTC
AATGAGGAGGAGCCTCCAGGTGGGCAAGACCCTTGGAAATTGCTGAAGGAGCAAGAGGAGCGGA
AGAAGTGTGTCATCTGCCAGGACCAGAGCAAGACAGTGTTGCTCCTGCCCTGCCGGCATCTGTG
CCTGTGCCAGGCCTGCACTGAAATCCTGATGCGCCACCCCGTCTACCACCGCAATTGCCCGCTC
TGCCGCCGGGGCATCCTGCAGACCCTCAATGTCTACCTCTGAAGCCTCCTTCCCTGCCTGCCCA
CCCCTCCATGCTCCACGCAGGCACTCACGCTAGGACAGCATTAACACCTCATCTCCGGGTCCTG
GTCTGAATCCCCTCCTACCCCTGTGGCCATCCTGCCATACATCCAGGACATTGAGTTGGAAGAC
TATGATCTGGGTGGGGGCAGGATAACATGGCTTCTCTTTACCCAGTGGGTCCCTTCGATGCTGA
GGGTGGTGAGTATGTCACTATGCAAGGGCCCTGAGACTATTTGCTGTGGGCTCTCCTCCAGCCT
GCCCAGGGCCCACCCAGATGCCTCTGGGGTTACCCCTGTCTGCTTCTGGTTTTTCTGTTGGAGA
TCTATAGGTCCTTTTCCTGCCTCCTTCACATTTCCTCCCCAGCTTTTGCGGCCACAACACATCA
GTGTCATTTGGGTGTTTTGGCAACTCAGGGGCCTTCGGATGATCTTAAACCTTTGTGTTCAGCC
AGAGCCCCTGTGCCCTGGTAGGCGTTGGGGTTAGTATCTCTCGGGTGCCCTCAGAGCCACCTCT
GCCTGTGATCGTCTGATGAGGCTCCCTCCCAACCTGATCCAAAAGCCAGTCTCAGGAGTTTACC
CCTGGGATGGGGGATGCATCTGCACCTGACTTTGGGGCCACGTGCCCTGTGGCACCCCAGCTCA
CTGGGAGTCTCAGGAGGGATAACCGGATTTCTGCTCTTTCCCCTGTCACTCCCACATCACACAG
AAAAATGGCATTCCTCTCTGTCTCTCCCTGGCATGGAGAGGGCAGACTGTGCACATTTCACTAG
GGTCCAAATACAGAAGGGCCCAGGGCCCAGGGGCTTGCAGCTTCGTGAGGGGTCTCTGGCCCAG
TTTCCAATGAATAAAGTTCTCTTGACAGCTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_114404	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH00058	(Get FASTA)	NCBI Sequence Viewer
	AAH07534	(Get FASTA)	NCBI Sequence Viewer
	BAB40955	(Get FASTA)	NCBI Sequence Viewer
	BAC11580	(Get FASTA)	NCBI Sequence Viewer
	BAG53635	(Get FASTA)	NCBI Sequence Viewer
	CAI72207	(Get FASTA)	NCBI Sequence Viewer
	EAW67479	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000312439
	ENSP00000312439.4
GenBank Protein	Q9BY78	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_114404 ⟸ NM_032015

- UniProtKB:

Q542Y8 (UniProtKB/Swiss-Prot), Q9BY78 (UniProtKB/Swiss-Prot), B3KV23 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEAVYLVVNGLGLVLDVLTLVLDLNFLLVSSLLASLAWLLAFVYNLPHTVLTSLLHLGRGVLLS
LLALIEAVVRFTCGGLQALCTLLYSCCSGLESLKLLGHLASHGALRSREILHRGVLNVVSSGHA
LLRQACDICAIAMSLVAYVINSLVNICLIGTQNLFSLVLALWDAVTGPLWRMTDVVAAFLAHIS
SSAVAMAILLWTPCQLALELLASAARLLASFVLVNLTGLVLLACVLAVTVTVLHPDFTLRLATQ
ALSQLHARPSYHRLREDVMRLSRLALGSEAWRRVWSRSLQLASWPNRGGAPGAPQGDPMRVFSV
RTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEEPPGGQDPWKLLKEQEERKKCVICQ
DQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCRRGILQTLNVYL

hide sequence

Ensembl Acc Id:

ENSP00000312439 ⟸ ENST00000311413

Protein Domains

RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9BY78-F1-model_v2	AlphaFold	Q9BY78	1-433	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:14646	AgrOrtholog
COSMIC	RNF26	COSMIC
Ensembl Genes	ENSG00000173456	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000311413	ENTREZGENE
	ENST00000311413.5	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000173456	GTEx
HGNC ID	HGNC:14646	ENTREZGENE
Human Proteome Map	RNF26	Human Proteome Map
InterPro	RNF26_mRING-HC-C3HC5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:79102	UniProtKB/Swiss-Prot
NCBI Gene	79102	ENTREZGENE
OMIM	606130	OMIM
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE RNF26	UniProtKB/Swiss-Prot
	E3 UBIQUITIN-PROTEIN LIGASE RNF26	UniProtKB/Swiss-Prot
	E3 UBIQUITIN-PROTEIN LIGASE RNF26	UniProtKB/TrEMBL
	E3 UBIQUITIN-PROTEIN LIGASE RNF26	UniProtKB/TrEMBL
Pfam	zf-C3HC4_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA34430	PharmGKB
PROSITE	ZF_RING_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	B3KV23	ENTREZGENE, UniProtKB/TrEMBL
	Q542Y8	ENTREZGENE
	Q9BY78	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q542Y8	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Human Phenotype Annotations - ClinVar

Send us a Message

Imported Disease Annotations - ClinVar

Imported Human Phenotype Annotations - ClinVar