Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of UBE2D2A mRNA | CTD | PMID:36331819 | (S)-nicotine | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 1,2-dimethylhydrazine | decreases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of UBE2D2 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of UBE2D2A mRNA | CTD | PMID:22206623 | 1,3-dinitrobenzene | increases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | 3-dinitrobenzene results in increased expression of UBE2D2 mRNA | CTD | PMID:24140754 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | decreases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 17alpha-ethynylestradiol | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBE2D2 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of UBE2D2 mRNA | CTD | PMID:17942748 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of UBE2D2 mRNA | CTD | PMID:19167446 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of UBE2D2 mRNA and Tetrachlorodibenzodioxin affects the expression of UBE2D2A mRNA | CTD | PMID:21570461 and PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of UBE2D2 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBE2D2 mRNA | CTD | PMID:17942748 | 2,4-dinitrotoluene | affects expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of UBE2D2 mRNA | CTD | PMID:21346803 | 3H-1,2-dithiole-3-thione | decreases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of UBE2D2 mRNA | CTD | PMID:19162173 | aflatoxin B1 | increases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of UBE2D2 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases methylation | EXP | | 6480464 | Aflatoxin B1 results in increased methylation of UBE2D2 intron | CTD | PMID:30157460 | amiodarone | increases expression | EXP | | 6480464 | Amiodarone results in increased expression of UBE2D2 mRNA | CTD | PMID:19774075 | ammonium chloride | affects expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of UBE2D2 mRNA | CTD | PMID:16483693 | antirheumatic drug | increases expression | EXP | | 6480464 | Antirheumatic Agents results in increased expression of UBE2D2 mRNA | CTD | PMID:24449571 | arsane | decreases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Arsenic results in decreased expression of UBE2D2 mRNA | CTD | PMID:24212999 | arsenic atom | decreases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Arsenic results in decreased expression of UBE2D2 mRNA | CTD | PMID:24212999 | arsenite(3-) | multiple interactions | EXP | | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to UBE2D2 mRNA] | CTD | PMID:32406909 | arsenous acid | multiple interactions | EXP | | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to UBE2D2 protein] | CTD | PMID:26598702 | benzo[a]pyrene diol epoxide I | decreases expression | EXP | | 6480464 | 7 more ... | CTD | PMID:19150397 | benzo[e]pyrene | decreases methylation | EXP | | 6480464 | benzo(e)pyrene results in decreased methylation of UBE2D2 intron | CTD | PMID:30157460 | biochanin A | decreases expression | EXP | | 6480464 | biochanin A results in decreased expression of UBE2D2 mRNA | CTD | PMID:12111696 | bis(2-ethylhexyl) phthalate | increases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Diethylhexyl Phthalate results in increased expression of UBE2D2 mRNA | CTD | PMID:21318169 | bisphenol A | increases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of UBE2D2 mRNA | CTD | PMID:25181051 | cadmium atom | decreases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Cadmium results in decreased expression of UBE2D2 and Cadmium results in decreased expression of UBE2D2 mRNA | CTD | PMID:21467746 and PMID:24212999 | cadmium atom | decreases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Cadmium results in decreased expression of UBE2D2 mRNA | CTD | PMID:21467746 | caffeine | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | calcium atom | affects expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Calcium affects the expression of UBE2D2 mRNA | CTD | PMID:15913539 | calcium(0) | affects expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Calcium affects the expression of UBE2D2 mRNA | CTD | PMID:15913539 | cannabidiol | increases expression | EXP | | 6480464 | Cannabidiol results in increased expression of UBE2D2 mRNA | CTD | PMID:28025562 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of UBE2D2 mRNA | CTD | PMID:19376846 | copper atom | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of UBE2D2 mRNA | CTD | PMID:15467011 | copper(0) | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of UBE2D2 mRNA | CTD | PMID:15467011 | coumestrol | decreases expression | EXP | | 6480464 | Coumestrol results in decreased expression of UBE2D2 mRNA | CTD | PMID:19167446 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of UBE2D2 mRNA | CTD | PMID:20106945 | delta-tocotrienol | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | tocotrienol and delta inhibits the reaction [Lipopolysaccharides results in decreased expression of UBE2D2A mRNA] | CTD | PMID:22185406 | delta-tocotrienol | decreases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | tocotrienol and delta results in decreased expression of UBE2D2A mRNA | CTD | PMID:22185406 | dexamethasone | decreases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Dexamethasone results in decreased expression of UBE2D2A mRNA | CTD | PMID:22185406 | dexamethasone | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | Dexamethasone inhibits the reaction [Lipopolysaccharides results in decreased expression of UBE2D2A mRNA] | CTD | PMID:22185406 | diarsenic trioxide | multiple interactions | EXP | | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to UBE2D2 protein] | CTD | PMID:26598702 | diazinon | increases methylation | EXP | | 6480464 | Diazinon results in increased methylation of UBE2D2 gene | CTD | PMID:22964155 | dibutyl phthalate | decreases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of UBE2D2 mRNA | CTD | PMID:17361019 and PMID:21266533 | dinophysistoxin 1 | increases expression | EXP | | 6480464 | dinophysistoxin 1 results in increased expression of UBE2D2 mRNA | CTD | PMID:28939011 | dioxygen | multiple interactions | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of UBE2D2 mRNA | CTD | PMID:33729688 | disodium selenite | increases expression | EXP | | 6480464 | Sodium Selenite results in increased expression of UBE2D2 mRNA | CTD | PMID:18175754 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of UBE2D2 mRNA | CTD | PMID:29803840 | epoxiconazole | increases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | epoxiconazole results in increased expression of UBE2D2A mRNA | CTD | PMID:35436446 | fenthion | decreases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Fenthion results in decreased expression of UBE2D2A mRNA | CTD | PMID:34813904 | folic acid | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of UBE2D2A mRNA | CTD | PMID:22206623 | gentamycin | increases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of UBE2D2 mRNA | CTD | PMID:22061828 | gonadorelin | increases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Gonadotropin-Releasing Hormone results in increased expression of UBE2D2 mRNA and Gonadotropin-Releasing Hormone results in increased expression of UBE2D2 protein | CTD | PMID:16055746 | lipopolysaccharide | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | Dexamethasone inhibits the reaction [Lipopolysaccharides results in decreased expression of UBE2D2A mRNA] more ... | CTD | PMID:22185406 | lipopolysaccharide | decreases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Lipopolysaccharides results in decreased expression of UBE2D2A mRNA | CTD | PMID:22185406 | methapyrilene | decreases methylation | EXP | | 6480464 | Methapyrilene results in decreased methylation of UBE2D2 intron | CTD | PMID:30157460 | methidathion | decreases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | methidathion results in decreased expression of UBE2D2A mRNA | CTD | PMID:34813904 | N-nitrosodiethylamine | decreases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Diethylnitrosamine results in decreased expression of UBE2D2 mRNA | CTD | PMID:19638242 | nicotine | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | paracetamol | affects expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Acetaminophen affects the expression of UBE2D2 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of UBE2D2 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of UBE2D2A mRNA | CTD | PMID:36331819 | phenytoin | increases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Phenytoin results in increased expression of UBE2D2 mRNA | CTD | PMID:20345932 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of UBE2D2 mRNA | CTD | PMID:19162173 | quercetin | decreases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Quercetin results in decreased expression of UBE2D2A mRNA | CTD | PMID:22185406 | quercetin | multiple interactions | ISO | Ube2d2a (Mus musculus) | 6480464 | Quercetin inhibits the reaction [Lipopolysaccharides results in decreased expression of UBE2D2A mRNA] | CTD | PMID:22185406 | rotenone | decreases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Rotenone results in decreased expression of UBE2D2 mRNA | CTD | PMID:23186747 | sunitinib | increases expression | EXP | | 6480464 | Sunitinib results in increased expression of UBE2D2 mRNA | CTD | PMID:31533062 | tamoxifen | increases expression | ISO | Ube2d2a (Mus musculus) | 6480464 | Tamoxifen results in increased expression of UBE2D2 mRNA | CTD | PMID:17555576 | trichloroethene | decreases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of UBE2D2 mRNA | CTD | PMID:33387578 | uranium atom | affects expression | EXP | | 6480464 | Uranium affects the expression of UBE2D2 mRNA | CTD | PMID:15672453 | valproic acid | increases expression | ISO | Ube2d2 (Rattus norvegicus) | 6480464 | Valproic Acid results in increased expression of UBE2D2 mRNA | CTD | PMID:21318169 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of UBE2D2 mRNA | CTD | PMID:23179753 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of UBE2D2 mRNA | CTD | PMID:25979313 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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