TRIM26 (tripartite motif containing 26) - Rat Genome Database

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Gene: TRIM26 (tripartite motif containing 26) Homo sapiens
Analyze
Symbol: TRIM26
Name: tripartite motif containing 26
RGD ID: 1346405
HGNC Page HGNC
Description: Predicted to enable ubiquitin protein ligase activity. Involved in several processes, including negative regulation of viral entry into host cell; negative regulation of viral release from host cell; and positive regulation of DNA-binding transcription factor activity. Predicted to be located in cytosol. Predicted to be active in cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acid finger protein; AFP; FLJ16483; RING finger protein 95; RNF95; tripartite motif-containing 26; tripartite motif-containing protein 26; widely expressed acid zinc finger protein; zinc finger protein 173; ZNF173
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: TRIM26BP  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl630,184,455 - 30,213,427 (-)EnsemblGRCh38hg38GRCh38
GRCh38630,184,453 - 30,213,435 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37630,152,232 - 30,181,183 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,260,211 - 30,289,132 (-)NCBINCBI36hg18NCBI36
Build 34630,260,212 - 30,289,132NCBI
Celera631,750,448 - 31,779,361 (-)NCBI
Cytogenetic Map6p22.1NCBI
HuRef629,950,359 - 29,979,394 (-)NCBIHuRef
CHM1_1630,154,280 - 30,183,313 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cellular_component  (ND)
cytoplasm  (IBA,ISO)
cytosol  (TAS)
nucleus  (IEA)

Molecular Function

References

Additional References at PubMed
PMID:8530076   PMID:9624122   PMID:11331580   PMID:12477932   PMID:14702039   PMID:15385968   PMID:15489334   PMID:16159877   PMID:16196087   PMID:16344560   PMID:17643375   PMID:18248090  
PMID:19394292   PMID:19549727   PMID:19851445   PMID:20593013   PMID:20805509   PMID:21139048   PMID:21145461   PMID:21516116   PMID:21750715   PMID:21873635   PMID:21890473   PMID:21906983  
PMID:21926974   PMID:21963094   PMID:21987572   PMID:21988832   PMID:22294275   PMID:22433715   PMID:22493164   PMID:22505724   PMID:22883433   PMID:22939629   PMID:23077300   PMID:23105109  
PMID:23453885   PMID:23667531   PMID:24457600   PMID:24489884   PMID:24623722   PMID:25147182   PMID:25416956   PMID:25544563   PMID:25693804   PMID:25763818   PMID:26043685   PMID:26186194  
PMID:26496610   PMID:26611359   PMID:26638075   PMID:26673895   PMID:26725010   PMID:26760575   PMID:28077445   PMID:28431233   PMID:28514442   PMID:28611215   PMID:28675297   PMID:28986522  
PMID:29229926   PMID:29395067   PMID:29509190   PMID:29610152   PMID:29845934   PMID:29911972   PMID:29956500   PMID:30232004   PMID:30471916   PMID:30927273   PMID:31495888   PMID:31527615  
PMID:31586073   PMID:31980649   PMID:32051553   PMID:32052576   PMID:32296183   PMID:32552912   PMID:32807901   PMID:32877691   PMID:33419081   PMID:33523994   PMID:33549581   PMID:34079125  


Genomics

Comparative Map Data
TRIM26
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl630,184,455 - 30,213,427 (-)EnsemblGRCh38hg38GRCh38
GRCh38630,184,453 - 30,213,435 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37630,152,232 - 30,181,183 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,260,211 - 30,289,132 (-)NCBINCBI36hg18NCBI36
Build 34630,260,212 - 30,289,132NCBI
Celera631,750,448 - 31,779,361 (-)NCBI
Cytogenetic Map6p22.1NCBI
HuRef629,950,359 - 29,979,394 (-)NCBIHuRef
CHM1_1630,154,280 - 30,183,313 (-)NCBICHM1_1
Trim26
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,148,016 - 37,170,290 (+)NCBIGRCm39mm39
GRCm39 Ensembl1737,148,026 - 37,170,290 (+)Ensembl
GRCm381736,837,123 - 36,859,398 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1736,837,134 - 36,859,398 (+)EnsemblGRCm38mm10GRCm38
MGSCv371736,974,086 - 36,996,325 (+)NCBIGRCm37mm9NCBIm37
MGSCv361736,445,234 - 36,467,430 (+)NCBImm8
Celera1740,256,349 - 40,278,617 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
Trim26
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2201,708,297 - 1,731,176 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl202,201,683 - 2,224,463 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0202,201,685 - 2,224,481 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0204,239,932 - 4,248,755 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,802,458 - 1,811,283 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1201,802,469 - 1,811,281 (-)NCBI
Celera202,418,533 - 2,427,356 (-)NCBICelera
Cytogenetic Map20p12NCBI
Trim26
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955583303,081 - 325,560 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955583303,081 - 325,560 (-)NCBIChiLan1.0ChiLan1.0
TRIM26
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1630,632,948 - 30,660,809 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl630,632,948 - 30,660,809 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0629,962,838 - 29,990,710 (-)NCBIMhudiblu_PPA_v0panPan3
Trim26
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494632,732,023 - 32,762,964 (-)NCBI
SpeTri2.0NW_004936723827,847 - 859,860 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM26
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,756,345 - 22,780,174 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,757,794 - 22,767,662 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2724,795,848 - 24,819,779 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM26
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11742,284,454 - 42,312,150 (+)NCBI
ChlSab1.1 Ensembl1742,283,713 - 42,313,292 (+)Ensembl
Vero_WHO_p1.0NW_02366604429,844,053 - 29,873,853 (-)NCBI
Trim26
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475425,238,992 - 25,258,454 (+)NCBI

Position Markers
RH93306  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,152,257 - 30,152,382UniSTSGRCh37
Build 36630,260,236 - 30,260,361RGDNCBI36
Celera631,750,473 - 31,750,598RGD
Cytogenetic Map6p21.3UniSTS
HuRef629,950,384 - 29,950,509UniSTS
GeneMap99-GB4 RH Map6117.36UniSTS
Trim26  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,153,680 - 30,154,335UniSTSGRCh37
Build 36630,261,659 - 30,262,314RGDNCBI36
Celera631,751,896 - 31,752,551RGD
HuRef629,951,807 - 29,952,462UniSTS
RH17987  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,152,445 - 30,152,600UniSTSGRCh37
Build 36630,260,424 - 30,260,579RGDNCBI36
Celera631,750,661 - 31,750,816RGD
Cytogenetic Map6p21.3UniSTS
HuRef629,950,572 - 29,950,727UniSTS
GeneMap99-GB4 RH Map6116.32UniSTS
NCBI RH Map6400.0UniSTS
D6S2704  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,176,650 - 30,176,813UniSTSGRCh37
GRCh37630,176,645 - 30,176,863UniSTSGRCh37
Build 36630,284,629 - 30,284,792RGDNCBI36
Celera631,774,846 - 31,775,068UniSTS
Celera631,774,851 - 31,775,018RGD
HuRef629,974,774 - 29,974,933UniSTS
HuRef629,974,769 - 29,974,983UniSTS
D6S2267  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,157,385 - 30,157,562UniSTSGRCh37
Build 36630,265,364 - 30,265,541RGDNCBI36
Celera631,755,596 - 31,755,773RGD
Cytogenetic Map6p21.3UniSTS
HuRef629,955,506 - 29,955,683UniSTS
D6S1944  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,152,276 - 30,152,601UniSTSGRCh37
Build 36630,260,255 - 30,260,580RGDNCBI36
Celera631,750,492 - 31,750,817RGD
Cytogenetic Map6p21.3UniSTS
HuRef629,950,403 - 29,950,728UniSTS
GeneMap99-GB4 RH Map6116.82UniSTS
GeneMap99-GB4 RH Map6117.03UniSTS
Whitehead-RH Map6164.0UniSTS
Whitehead-YAC Contig Map6 UniSTS
NCBI RH Map6474.2UniSTS
D6S2198  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,171,600 - 30,171,749UniSTSGRCh37
Build 36630,279,579 - 30,279,728RGDNCBI36
Celera631,769,802 - 31,769,951RGD
Cytogenetic Map6p21.3UniSTS
HuRef629,969,726 - 29,969,875UniSTS
RH37470  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,181,547 - 30,181,669UniSTSGRCh37
Build 36630,289,526 - 30,289,648RGDNCBI36
Celera631,779,755 - 31,779,878RGD
Cytogenetic Map6p21.3UniSTS
HuRef629,979,670 - 29,979,792UniSTS
GeneMap99-GB4 RH Map6116.53UniSTS
C5_2_3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,176,511 - 30,176,815UniSTSGRCh37
Build 36630,284,490 - 30,284,794RGDNCBI36
Celera631,774,712 - 31,775,020RGD
Cytogenetic Map6p21.3UniSTS
HuRef629,974,635 - 29,974,935UniSTS
D6S2848  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37630,176,590 - 30,176,772UniSTSGRCh37
Build 36630,284,569 - 30,284,751RGDNCBI36
Celera631,774,791 - 31,774,977RGD
HuRef629,974,714 - 29,974,892UniSTS
D6S2704  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6p21.3UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3854
Count of miRNA genes:972
Interacting mature miRNAs:1159
Transcripts:ENST00000416596, ENST00000418026, ENST00000434785, ENST00000437089, ENST00000453195, ENST00000454678, ENST00000480999, ENST00000487829
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2427 2299 1710 617 1812 458 3937 1429 3139 401 1451 1606 171 1204 2369 4 2
Low 12 692 16 7 139 7 420 768 595 18 9 7 4 1 419 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001242783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005249374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005249375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005249376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005249377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005249378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006715180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011514859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017011263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB088090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB103596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB202086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK096996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK314782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL671855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL844220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL845450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BA000025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX248419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX927189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX927221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB988131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR388382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR759838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR788282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA234548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000416596   ⟹   ENSP00000413673
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,196,536 - 30,213,419 (-)Ensembl
RefSeq Acc Id: ENST00000418026   ⟹   ENSP00000387530
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,198,491 - 30,213,385 (-)Ensembl
RefSeq Acc Id: ENST00000434785   ⟹   ENSP00000400920
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,198,738 - 30,213,366 (-)Ensembl
RefSeq Acc Id: ENST00000437089   ⟹   ENSP00000395491
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,184,455 - 30,204,765 (-)Ensembl
RefSeq Acc Id: ENST00000453195   ⟹   ENSP00000391879
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,184,455 - 30,213,427 (-)Ensembl
RefSeq Acc Id: ENST00000454678   ⟹   ENSP00000410446
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,184,455 - 30,213,406 (-)Ensembl
RefSeq Acc Id: ENST00000480999
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,184,455 - 30,190,394 (-)Ensembl
RefSeq Acc Id: ENST00000487829
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl630,198,764 - 30,213,365 (-)Ensembl
RefSeq Acc Id: NM_001242783   ⟹   NP_001229712
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,184,455 - 30,213,406 (-)NCBI
GRCh37630,152,232 - 30,181,271 (-)ENTREZGENE
HuRef629,950,359 - 29,979,394 (-)ENTREZGENE
CHM1_1630,154,280 - 30,183,313 (-)NCBI
Sequence:
RefSeq Acc Id: NM_003449   ⟹   NP_003440
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,184,455 - 30,213,406 (-)NCBI
GRCh37630,152,232 - 30,181,271 (-)ENTREZGENE
Build 36630,260,211 - 30,289,132 (-)NCBI Archive
Celera631,750,448 - 31,779,361 (-)RGD
HuRef629,950,359 - 29,979,394 (-)ENTREZGENE
CHM1_1630,154,280 - 30,183,313 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005249374   ⟹   XP_005249431
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,184,453 - 30,213,401 (-)NCBI
GRCh37630,152,232 - 30,181,271 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005249375   ⟹   XP_005249432
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,184,453 - 30,213,424 (-)NCBI
GRCh37630,152,232 - 30,181,271 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005249376   ⟹   XP_005249433
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,184,453 - 30,213,385 (-)NCBI
GRCh37630,152,232 - 30,181,271 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005249377   ⟹   XP_005249434
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,184,453 - 30,213,366 (-)NCBI
GRCh37630,152,232 - 30,181,271 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005249378   ⟹   XP_005249435
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,184,453 - 30,213,435 (-)NCBI
GRCh37630,152,232 - 30,181,271 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006715180   ⟹   XP_006715243
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,184,453 - 30,213,424 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011514859   ⟹   XP_011513161
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,184,453 - 30,213,401 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017011263   ⟹   XP_016866752
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,184,453 - 30,213,435 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001229712 (Get FASTA)   NCBI Sequence Viewer  
  NP_003440 (Get FASTA)   NCBI Sequence Viewer  
  XP_005249431 (Get FASTA)   NCBI Sequence Viewer  
  XP_005249432 (Get FASTA)   NCBI Sequence Viewer  
  XP_005249433 (Get FASTA)   NCBI Sequence Viewer  
  XP_005249434 (Get FASTA)   NCBI Sequence Viewer  
  XP_005249435 (Get FASTA)   NCBI Sequence Viewer  
  XP_006715243 (Get FASTA)   NCBI Sequence Viewer  
  XP_011513161 (Get FASTA)   NCBI Sequence Viewer  
  XP_016866752 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH24039 (Get FASTA)   NCBI Sequence Viewer  
  AAH32297 (Get FASTA)   NCBI Sequence Viewer  
  AQY77163 (Get FASTA)   NCBI Sequence Viewer  
  AQY77164 (Get FASTA)   NCBI Sequence Viewer  
  AQY77165 (Get FASTA)   NCBI Sequence Viewer  
  AQY77166 (Get FASTA)   NCBI Sequence Viewer  
  AQY77167 (Get FASTA)   NCBI Sequence Viewer  
  AQY77168 (Get FASTA)   NCBI Sequence Viewer  
  AQY77169 (Get FASTA)   NCBI Sequence Viewer  
  BAB63330 (Get FASTA)   NCBI Sequence Viewer  
  BAC54923 (Get FASTA)   NCBI Sequence Viewer  
  BAE78607 (Get FASTA)   NCBI Sequence Viewer  
  BAF31258 (Get FASTA)   NCBI Sequence Viewer  
  EAX03272 (Get FASTA)   NCBI Sequence Viewer  
  EAX03273 (Get FASTA)   NCBI Sequence Viewer  
  EAX03274 (Get FASTA)   NCBI Sequence Viewer  
  EAX03275 (Get FASTA)   NCBI Sequence Viewer  
  EAX03276 (Get FASTA)   NCBI Sequence Viewer  
  Q12899 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_003440   ⟸   NM_003449
- UniProtKB: Q12899 (UniProtKB/Swiss-Prot),   A0A024RCP3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001229712   ⟸   NM_001242783
- UniProtKB: Q12899 (UniProtKB/Swiss-Prot),   A0A024RCP3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005249435   ⟸   XM_005249378
- Peptide Label: isoform X1
- UniProtKB: Q12899 (UniProtKB/Swiss-Prot),   A0A024RCP3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005249432   ⟸   XM_005249375
- Peptide Label: isoform X1
- UniProtKB: Q12899 (UniProtKB/Swiss-Prot),   A0A024RCP3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005249431   ⟸   XM_005249374
- Peptide Label: isoform X1
- UniProtKB: Q12899 (UniProtKB/Swiss-Prot),   A0A024RCP3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005249433   ⟸   XM_005249376
- Peptide Label: isoform X1
- UniProtKB: Q12899 (UniProtKB/Swiss-Prot),   A0A024RCP3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005249434   ⟸   XM_005249377
- Peptide Label: isoform X1
- UniProtKB: Q12899 (UniProtKB/Swiss-Prot),   A0A024RCP3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006715243   ⟸   XM_006715180
- Peptide Label: isoform X1
- UniProtKB: Q12899 (UniProtKB/Swiss-Prot),   A0A024RCP3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011513161   ⟸   XM_011514859
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_016866752   ⟸   XM_017011263
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSP00000391879   ⟸   ENST00000453195
RefSeq Acc Id: ENSP00000410446   ⟸   ENST00000454678
RefSeq Acc Id: ENSP00000413673   ⟸   ENST00000416596
RefSeq Acc Id: ENSP00000387530   ⟸   ENST00000418026
RefSeq Acc Id: ENSP00000400920   ⟸   ENST00000434785
RefSeq Acc Id: ENSP00000395491   ⟸   ENST00000437089
Protein Domains
B box-type   B30.2/SPRY   RING-type

Promoters
RGD ID:6872366
Promoter ID:EPDNEW_H9347
Type:initiation region
Name:TRIM26_1
Description:tripartite motif containing 26
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38630,213,363 - 30,213,423EPDNEW
RGD ID:6813111
Promoter ID:HG_ACW:67897
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid
Transcripts:TRIM26.IAPR07-UNSPLICED
Position:
Human AssemblyChrPosition (strand)Source
Build 36630,260,546 - 30,262,092 (-)MPROMDB
RGD ID:6804886
Promoter ID:HG_KWN:52808
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:OTTHUMT00000253444
Position:
Human AssemblyChrPosition (strand)Source
Build 36630,266,166 - 30,266,802 (-)MPROMDB
RGD ID:6804887
Promoter ID:HG_KWN:52810
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000396558,   NM_003449,   OTTHUMT00000253445,   OTTHUMT00000253446,   OTTHUMT00000253447,   OTTHUMT00000253448,   UC010JRY.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36630,289,046 - 30,290,052 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6p22.3-21.33(chr6:18120520-30767516)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|See cases [RCV000052180] Chr6:18120520..30767516 [GRCh38]
Chr6:18120751..30735293 [GRCh37]
Chr6:18228730..30843272 [NCBI36]
Chr6:6p22.3-21.33
pathogenic
NM_001242783.1(TRIM26):c.860C>T (p.Ser287Leu) single nucleotide variant Malignant melanoma [RCV000067264] Chr6:30189462 [GRCh38]
Chr6:30157239 [GRCh37]
Chr6:30265218 [NCBI36]
Chr6:6p22.1
not provided
GRCh38/hg38 6p25.2-21.33(chr6:3224310-30657190)x3 copy number gain See cases [RCV000138956] Chr6:3224310..30657190 [GRCh38]
Chr6:3224544..30624967 [GRCh37]
Chr6:3169543..30732946 [NCBI36]
Chr6:6p25.2-21.33
pathogenic
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p22.1-21.32(chr6:28130359-32108367)x3 copy number gain not provided [RCV000745592] Chr6:28130359..32108367 [GRCh37]
Chr6:6p22.1-21.32
uncertain significance
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367) copy number gain not provided [RCV000767714] Chr6:29455465..81447367 [GRCh37]
Chr6:6p22.1-q14.1
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:12962 AgrOrtholog
COSMIC TRIM26 COSMIC
Ensembl Genes ENSG00000137313 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000226060 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000228881 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000230230 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000231002 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000231641 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000234046 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000234127 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000331131 UniProtKB/Swiss-Prot
  ENSP00000373102 UniProtKB/Swiss-Prot
  ENSP00000379806 UniProtKB/Swiss-Prot
  ENSP00000387530 UniProtKB/TrEMBL
  ENSP00000388005 UniProtKB/TrEMBL
  ENSP00000389203 UniProtKB/Swiss-Prot
  ENSP00000389386 UniProtKB/TrEMBL
  ENSP00000390258 UniProtKB/Swiss-Prot
  ENSP00000390908 UniProtKB/TrEMBL
  ENSP00000391031 UniProtKB/TrEMBL
  ENSP00000391602 UniProtKB/TrEMBL
  ENSP00000391879 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000392805 UniProtKB/Swiss-Prot
  ENSP00000393011 UniProtKB/Swiss-Prot
  ENSP00000393753 UniProtKB/TrEMBL
  ENSP00000393827 UniProtKB/TrEMBL
  ENSP00000394371 UniProtKB/Swiss-Prot
  ENSP00000394421 UniProtKB/Swiss-Prot
  ENSP00000395491 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000395820 UniProtKB/TrEMBL
  ENSP00000396089 UniProtKB/TrEMBL
  ENSP00000396188 UniProtKB/Swiss-Prot
  ENSP00000397048 UniProtKB/TrEMBL
  ENSP00000398545 UniProtKB/Swiss-Prot
  ENSP00000400655 UniProtKB/TrEMBL
  ENSP00000400920 UniProtKB/TrEMBL
  ENSP00000402135 UniProtKB/TrEMBL
  ENSP00000402395 UniProtKB/Swiss-Prot
  ENSP00000402684 UniProtKB/TrEMBL
  ENSP00000402990 UniProtKB/TrEMBL
  ENSP00000403395 UniProtKB/TrEMBL
  ENSP00000403765 UniProtKB/TrEMBL
  ENSP00000403887 UniProtKB/TrEMBL
  ENSP00000405526 UniProtKB/TrEMBL
  ENSP00000405710 UniProtKB/TrEMBL
  ENSP00000405791 UniProtKB/TrEMBL
  ENSP00000405923 UniProtKB/TrEMBL
  ENSP00000406707 UniProtKB/Swiss-Prot
  ENSP00000407035 UniProtKB/TrEMBL
  ENSP00000407294 UniProtKB/Swiss-Prot
  ENSP00000407876 UniProtKB/Swiss-Prot
  ENSP00000408233 UniProtKB/Swiss-Prot
  ENSP00000409182 UniProtKB/Swiss-Prot
  ENSP00000410446 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000412165 UniProtKB/TrEMBL
  ENSP00000412641 UniProtKB/TrEMBL
  ENSP00000412838 UniProtKB/TrEMBL
  ENSP00000413673 UniProtKB/TrEMBL
  ENSP00000414248 UniProtKB/Swiss-Prot
  ENSP00000415328 UniProtKB/Swiss-Prot
  ENSP00000415755 UniProtKB/Swiss-Prot
  ENSP00000416276 UniProtKB/TrEMBL
  ENSP00000416664 UniProtKB/TrEMBL
  ENSP00000416737 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000327357 UniProtKB/Swiss-Prot
  ENST00000383607 UniProtKB/Swiss-Prot
  ENST00000396558 UniProtKB/Swiss-Prot
  ENST00000412755 UniProtKB/TrEMBL
  ENST00000415789 UniProtKB/TrEMBL
  ENST00000415923 UniProtKB/Swiss-Prot
  ENST00000415966 UniProtKB/TrEMBL
  ENST00000416596 UniProtKB/TrEMBL
  ENST00000418026 UniProtKB/TrEMBL
  ENST00000419171 UniProtKB/TrEMBL
  ENST00000419401 UniProtKB/TrEMBL
  ENST00000422349 UniProtKB/Swiss-Prot
  ENST00000422802 UniProtKB/TrEMBL
  ENST00000422881 UniProtKB/TrEMBL
  ENST00000423901 UniProtKB/TrEMBL
  ENST00000424124 UniProtKB/TrEMBL
  ENST00000425523 UniProtKB/Swiss-Prot
  ENST00000425831 UniProtKB/Swiss-Prot
  ENST00000427535 UniProtKB/Swiss-Prot
  ENST00000427612 UniProtKB/TrEMBL
  ENST00000428486 UniProtKB/Swiss-Prot
  ENST00000429583 UniProtKB/TrEMBL
  ENST00000431641 UniProtKB/TrEMBL
  ENST00000432326 UniProtKB/Swiss-Prot
  ENST00000433314 UniProtKB/Swiss-Prot
  ENST00000433361 UniProtKB/TrEMBL
  ENST00000433836 UniProtKB/TrEMBL
  ENST00000434785 UniProtKB/TrEMBL
  ENST00000435387 UniProtKB/TrEMBL
  ENST00000436219 UniProtKB/Swiss-Prot
  ENST00000437089 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000438064 UniProtKB/TrEMBL
  ENST00000438384 UniProtKB/Swiss-Prot
  ENST00000438785 UniProtKB/TrEMBL
  ENST00000438908 UniProtKB/Swiss-Prot
  ENST00000439094 UniProtKB/Swiss-Prot
  ENST00000440149 UniProtKB/TrEMBL
  ENST00000444979 UniProtKB/TrEMBL
  ENST00000445259 UniProtKB/Swiss-Prot
  ENST00000445457 UniProtKB/TrEMBL
  ENST00000446196 UniProtKB/TrEMBL
  ENST00000446540 UniProtKB/TrEMBL
  ENST00000447711 UniProtKB/Swiss-Prot
  ENST00000447942 UniProtKB/TrEMBL
  ENST00000449136 UniProtKB/TrEMBL
  ENST00000450103 UniProtKB/TrEMBL
  ENST00000450392 UniProtKB/Swiss-Prot
  ENST00000451189 UniProtKB/TrEMBL
  ENST00000453195 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000453442 UniProtKB/TrEMBL
  ENST00000454678 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000455000 UniProtKB/Swiss-Prot
  ENST00000456093 UniProtKB/Swiss-Prot
  ENST00000456770 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.920 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000137313 GTEx
  ENSG00000226060 GTEx
  ENSG00000228881 GTEx
  ENSG00000230230 GTEx
  ENSG00000231002 GTEx
  ENSG00000231641 GTEx
  ENSG00000234046 GTEx
  ENSG00000234127 GTEx
HGNC ID HGNC:12962 ENTREZGENE
Human Proteome Map TRIM26 Human Proteome Map
InterPro B30.2/SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_B-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_B-box_chordata UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:7726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 7726 ENTREZGENE
OMIM 600830 OMIM
Pfam PRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-B_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA37544 PharmGKB
PRINTS BBOXZNFINGER UniProtKB/TrEMBL
  BUTYPHLNCDUF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024RCP3 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JIW2_HUMAN UniProtKB/TrEMBL
  A2AE48_HUMAN UniProtKB/TrEMBL
  A2AE50_HUMAN UniProtKB/TrEMBL
  Q12899 ENTREZGENE
  Q5SPU2_HUMAN UniProtKB/TrEMBL
  TRI26_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary A6NG96 UniProtKB/Swiss-Prot
  Q5SRL2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-09-01 TRIM26  tripartite motif containing 26  TRIM26  tripartite motif containing 26  Symbol and/or name change 5135510 APPROVED
2011-07-27 TRIM26  tripartite motif containing 26  TRIM26  tripartite motif-containing 26  Symbol and/or name change 5135510 APPROVED