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Gene: BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase) Homo sapiens
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Symbol: BTRC
Name: beta-transducin repeat containing E3 ubiquitin protein ligase
Description: Exhibits beta-catenin binding activity. Contributes to ubiquitin protein ligase activity. Involved in several processes, including cellular protein metabolic process; positive regulation of proteolysis; and protein destabilization. Localizes to SCF ubiquitin ligase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BETA-TRCP; beta-TrCP1; betaTrCP; bTrCP; bTrCP1; E3RSIkappaB; epididymis tissue protein Li 2a; F-box and WD repeats protein beta-TrCP; F-box and WD-repeat protein 1B; F-box/WD repeat-containing protein 1A; FBW1A; FBXW1; FBXW1A; FWD1; MGC4643; pIkappaBalpha-E3 receptor subunit
Orthologs:
Related Pseudogenes: BTRCP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl10101,354,033 - 101,557,321 (+)EnsemblGRCh38hg38GRCh38
GRCh3810101,353,808 - 101,557,321 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710103,113,790 - 103,317,078 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610103,103,815 - 103,307,060 (+)NCBINCBI36hg18NCBI36
Build 3410103,103,814 - 103,307,058NCBI
Celera1096,852,547 - 97,055,847 (+)NCBI
Cytogenetic Map10q24.32NCBI
HuRef1096,743,700 - 96,947,675 (+)NCBIHuRef
CHM1_110103,397,663 - 103,600,757 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on BTRC
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1347748
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.