TRIM49C (tripartite motif containing 49C) - Rat Genome Database

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Gene: TRIM49C (tripartite motif containing 49C) Homo sapiens
Analyze
Symbol: TRIM49C
Name: tripartite motif containing 49C
RGD ID: 4143019
HGNC Page HGNC:38877
Description: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response and regulation of gene expression. Predicted to be active in cytoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC105378955; MGC161748; TRIM49L2; tripartite motif containing 49-like 2; tripartite motif-containing 49-like; tripartite motif-containing 49-like 2; tripartite motif-containing protein 43B; tripartite motif-containing protein 49-like protein 2; tripartite motif-containing protein 49C; Tripartite motif-containing protein LOC642612
RGD Orthologs
Dog
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381190,031,106 - 90,073,531 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1190,031,106 - 90,042,025 (+)EnsemblGRCh38hg38GRCh38
GRCh371189,764,274 - 89,775,193 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera1185,128,446 - 85,131,645 (+)NCBICelera
Cytogenetic Map11q14.3NCBI
HuRef1185,850,878 - 85,860,267 (+)NCBIHuRef
CHM1_11189,647,260 - 89,658,191 (+)NCBICHM1_1
T2T-CHM13v2.01189,951,193 - 89,993,609 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:15815621   PMID:16554811   PMID:21873635   PMID:22144910   PMID:32296183   PMID:34373451  


Genomics

Comparative Map Data
TRIM49C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381190,031,106 - 90,073,531 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1190,031,106 - 90,042,025 (+)EnsemblGRCh38hg38GRCh38
GRCh371189,764,274 - 89,775,193 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera1185,128,446 - 85,131,645 (+)NCBICelera
Cytogenetic Map11q14.3NCBI
HuRef1185,850,878 - 85,860,267 (+)NCBIHuRef
CHM1_11189,647,260 - 89,658,191 (+)NCBICHM1_1
T2T-CHM13v2.01189,951,193 - 89,993,609 (+)NCBIT2T-CHM13v2.0
LOC608075
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12110,341,561 - 10,373,222 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2110,194,843 - 10,224,001 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02110,439,966 - 10,463,159 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12110,242,704 - 10,257,826 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02110,301,739 - 10,316,873 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02110,343,747 - 10,366,938 (+)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in TRIM49C
33 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3		 pathogenic
GRCh38/hg38 11q14.1-22.3(chr11:78232836-106779420)x1 copy number loss See cases [RCV000052710] Chr11:78232836..106779420 [GRCh38]
Chr11:77943882..106650146 [GRCh37]
Chr11:77621530..106155356 [NCBI36]
Chr11:11q14.1-22.3		 pathogenic
GRCh38/hg38 11q14.1-22.2(chr11:85242847-102920097)x1 copy number loss See cases [RCV000052711] Chr11:85242847..102920097 [GRCh38]
Chr11:84953891..102738968 [GRCh37]
Chr11:84631539..102296037 [NCBI36]
Chr11:11q14.1-22.2		 pathogenic
NM_001195234.1(TRIM49C):c.910G>A (p.Glu304Lys) single nucleotide variant Malignant melanoma [RCV000069738] Chr11:90041101 [GRCh38]
Chr11:89774269 [GRCh37]
Chr11:89413917 [NCBI36]
Chr11:11q14.3		 not provided
GRCh38/hg38 11q13.5-22.1(chr11:75941754-98357960)x1 copy number loss See cases [RCV000133838] Chr11:75941754..98357960 [GRCh38]
Chr11:75652798..98228688 [GRCh37]
Chr11:75330446..97733898 [NCBI36]
Chr11:11q13.5-22.1		 pathogenic
GRCh38/hg38 11q14.3(chr11:89650515-90084741)x1 copy number loss See cases [RCV000137458] Chr11:89650515..90084741 [GRCh38]
Chr11:89383683..89817909 [GRCh37]
Chr11:89023331..89457557 [NCBI36]
Chr11:11q14.3		 pathogenic|likely benign
GRCh38/hg38 11q14.3(chr11:89425778-90689442)x1 copy number loss See cases [RCV000141934] Chr11:89425778..90689442 [GRCh38]
Chr11:89158946..90422610 [GRCh37]
Chr11:88798594..90062258 [NCBI36]
Chr11:11q14.3		 uncertain significance
GRCh37/hg19 11q14.1-21(chr11:80318996-96116221)x1 copy number loss See cases [RCV000446395] Chr11:80318996..96116221 [GRCh37]
Chr11:11q14.1-21		 pathogenic
GRCh37/hg19 11q14.3(chr11:89540275-89956475)x3 copy number gain See cases [RCV000448705] Chr11:89540275..89956475 [GRCh37]
Chr11:11q14.3		 benign
GRCh37/hg19 11q14.3(chr11:89514122-92745981)x1 copy number loss See cases [RCV000448827] Chr11:89514122..92745981 [GRCh37]
Chr11:11q14.3		 uncertain significance
GRCh37/hg19 11q14.2-14.3(chr11:87099219-91921385) copy number loss Abnormal esophagus morphology [RCV000416734] Chr11:87099219..91921385 [GRCh37]
Chr11:11q14.2-14.3		 likely benign
GRCh37/hg19 11q14.1-21(chr11:84924674-93574799)x1 copy number loss See cases [RCV000448436] Chr11:84924674..93574799 [GRCh37]
Chr11:11q14.1-21		 likely pathogenic
GRCh37/hg19 11q14.2-22.3(chr11:88152458-109414650)x1 copy number loss See cases [RCV000510457] Chr11:88152458..109414650 [GRCh37]
Chr11:11q14.2-22.3		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
NM_001195234.1(TRIM49C):c.328C>A (p.Leu110Met) single nucleotide variant not specified [RCV004321960] Chr11:90035539 [GRCh38]
Chr11:89768707 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.887C>A (p.Ala296Asp) single nucleotide variant not specified [RCV004326648] Chr11:90041078 [GRCh38]
Chr11:89774246 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.1223G>A (p.Arg408Gln) single nucleotide variant not specified [RCV004298556] Chr11:90041414 [GRCh38]
Chr11:89774582 [GRCh37]
Chr11:11q14.3		 uncertain significance
GRCh37/hg19 11q13.4-23.3(chr11:71588805-116680918)x3 copy number gain not provided [RCV000683374] Chr11:71588805..116680918 [GRCh37]
Chr11:11q13.4-23.3		 pathogenic
GRCh37/hg19 11q14.1-14.3(chr11:81771852-90851187) copy number loss Intellectual disability [RCV000721939] Chr11:81771852..90851187 [GRCh37]
Chr11:11q14.1-14.3		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11q14.1-23.2(chr11:80053454-113316236)x1 copy number loss not provided [RCV000737595] Chr11:80053454..113316236 [GRCh37]
Chr11:11q14.1-23.2		 pathogenic
GRCh37/hg19 11q14.1-21(chr11:83179196-94716998)x3 copy number gain not provided [RCV000750120] Chr11:83179196..94716998 [GRCh37]
Chr11:11q14.1-21		 pathogenic
Single allele deletion Neurodevelopmental disorder [RCV000787372] Chr11:89482692..90933956 [GRCh37]
Chr11:11q14.3		 uncertain significance
GRCh37/hg19 11q14.3(chr11:89659554-90697895)x3 copy number gain not provided [RCV001006433] Chr11:89659554..90697895 [GRCh37]
Chr11:11q14.3		 uncertain significance
GRCh37/hg19 11q14.1-14.3(chr11:84830143-92029933)x3 copy number gain not provided [RCV001006426] Chr11:84830143..92029933 [GRCh37]
Chr11:11q14.1-14.3		 pathogenic
NM_001195234.1(TRIM49C):c.236A>G (p.Lys79Arg) single nucleotide variant not specified [RCV004684731] Chr11:90035447 [GRCh38]
Chr11:89768615 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.1127G>T (p.Gly376Val) single nucleotide variant not specified [RCV004684737] Chr11:90041318 [GRCh38]
Chr11:89774486 [GRCh37]
Chr11:11q14.3		 uncertain significance
GRCh37/hg19 11q14.1-22.1(chr11:77855209-98002445) copy number loss not specified [RCV002052940] Chr11:77855209..98002445 [GRCh37]
Chr11:11q14.1-22.1		 pathogenic
GRCh37/hg19 11q14.1-21(chr11:80318996-96116221) copy number loss not specified [RCV002052941] Chr11:80318996..96116221 [GRCh37]
Chr11:11q14.1-21		 pathogenic
GRCh37/hg19 11q14.1-23.3(chr11:85422071-118022671)x1 copy number loss not provided [RCV001832892] Chr11:85422071..118022671 [GRCh37]
Chr11:11q14.1-23.3		 uncertain significance
GRCh37/hg19 11q14.1-21(chr11:84924674-93574799) copy number loss not specified [RCV002052942] Chr11:84924674..93574799 [GRCh37]
Chr11:11q14.1-21		 likely pathogenic
GRCh37/hg19 11q14.3(chr11:89514122-92745981) copy number loss not specified [RCV002052946] Chr11:89514122..92745981 [GRCh37]
Chr11:11q14.3		 uncertain significance
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25		 pathogenic
GRCh37/hg19 11q14.3(chr11:89474818-89887082)x1 copy number loss not provided [RCV002474964] Chr11:89474818..89887082 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.212A>G (p.Lys71Arg) single nucleotide variant not specified [RCV004200293] Chr11:90035423 [GRCh38]
Chr11:89768591 [GRCh37]
Chr11:11q14.3		 uncertain significance
GRCh37/hg19 11q14.1-22.3(chr11:81478509-104667040)x1 copy number loss not provided [RCV002475722] Chr11:81478509..104667040 [GRCh37]
Chr11:11q14.1-22.3		 pathogenic
NM_001195234.1(TRIM49C):c.91G>A (p.Gly31Arg) single nucleotide variant not specified [RCV004153998] Chr11:90035302 [GRCh38]
Chr11:89768470 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.980G>T (p.Ser327Ile) single nucleotide variant not specified [RCV004089302] Chr11:90041171 [GRCh38]
Chr11:89774339 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.356A>T (p.Gln119Leu) single nucleotide variant not specified [RCV004210702] Chr11:90035567 [GRCh38]
Chr11:89768735 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.500G>T (p.Cys167Phe) single nucleotide variant not specified [RCV004107799] Chr11:90035976 [GRCh38]
Chr11:89769144 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.179A>G (p.Glu60Gly) single nucleotide variant not specified [RCV004186666] Chr11:90035390 [GRCh38]
Chr11:89768558 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.740C>G (p.Ala247Gly) single nucleotide variant not specified [RCV004123220] Chr11:90038694 [GRCh38]
Chr11:89771862 [GRCh37]
Chr11:11q14.3		 likely benign
NM_001195234.1(TRIM49C):c.409C>T (p.Arg137Trp) single nucleotide variant not specified [RCV004089226] Chr11:90035620 [GRCh38]
Chr11:89768788 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.784A>G (p.Met262Val) single nucleotide variant not specified [RCV004190847] Chr11:90039887 [GRCh38]
Chr11:89773055 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.274A>C (p.Met92Leu) single nucleotide variant not specified [RCV004201032] Chr11:90035485 [GRCh38]
Chr11:89768653 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.785T>C (p.Met262Thr) single nucleotide variant not specified [RCV004203323] Chr11:90039888 [GRCh38]
Chr11:89773056 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.319G>A (p.Asp107Asn) single nucleotide variant not specified [RCV004231680] Chr11:90035530 [GRCh38]
Chr11:89768698 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.185T>G (p.Ile62Arg) single nucleotide variant not specified [RCV004203246] Chr11:90035396 [GRCh38]
Chr11:89768564 [GRCh37]
Chr11:11q14.3		 likely benign
NM_001195234.1(TRIM49C):c.702C>G (p.Asn234Lys) single nucleotide variant not specified [RCV004131648] Chr11:90037943 [GRCh38]
Chr11:89771111 [GRCh37]
Chr11:11q14.3		 likely benign
NM_001195234.1(TRIM49C):c.424C>A (p.Gln142Lys) single nucleotide variant not specified [RCV004260181] Chr11:90035900 [GRCh38]
Chr11:89769068 [GRCh37]
Chr11:11q14.3		 likely benign
NM_001195234.1(TRIM49C):c.1022A>G (p.Tyr341Cys) single nucleotide variant not specified [RCV004256515] Chr11:90041213 [GRCh38]
Chr11:89774381 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.878A>G (p.His293Arg) single nucleotide variant not specified [RCV004325549] Chr11:90041069 [GRCh38]
Chr11:89774237 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.210G>C (p.Leu70Phe) single nucleotide variant not specified [RCV004684732] Chr11:90035421 [GRCh38]
Chr11:89768589 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.1045G>A (p.Asp349Asn) single nucleotide variant not specified [RCV004684736] Chr11:90041236 [GRCh38]
Chr11:89774404 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.1044G>T (p.Gly348=) single nucleotide variant not provided [RCV003395992] Chr11:90041235 [GRCh38]
Chr11:89774403 [GRCh37]
Chr11:11q14.3		 likely benign
NC_000011.10:g.90072986C>T single nucleotide variant not provided [RCV003395994] Chr11:90072986 [GRCh38]
Chr11:89806154 [GRCh37]
Chr11:11q14.3		 likely benign
GRCh37/hg19 11q14.3(chr11:89602560-90979365)x3 copy number gain not provided [RCV003484848] Chr11:89602560..90979365 [GRCh37]
Chr11:11q14.3		 uncertain significance
NC_000011.10:g.90072950G>A single nucleotide variant not provided [RCV003395993] Chr11:90072950 [GRCh38]
Chr11:89806118 [GRCh37]
Chr11:11q14.3		 likely benign
NM_001195234.1(TRIM49C):c.1283G>C (p.Ser428Thr) single nucleotide variant not specified [RCV004475941] Chr11:90041474 [GRCh38]
Chr11:89774642 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.364C>T (p.Arg122Trp) single nucleotide variant not specified [RCV004475942] Chr11:90035575 [GRCh38]
Chr11:89768743 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.823A>T (p.Ile275Phe) single nucleotide variant not specified [RCV004475944] Chr11:90039926 [GRCh38]
Chr11:89773094 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.927G>A (p.Met309Ile) single nucleotide variant not specified [RCV004475945] Chr11:90041118 [GRCh38]
Chr11:89774286 [GRCh37]
Chr11:11q14.3		 uncertain significance
NM_001195234.1(TRIM49C):c.703G>A (p.Glu235Lys) single nucleotide variant not specified [RCV004475943] Chr11:90037944 [GRCh38]
Chr11:89771112 [GRCh37]
Chr11:11q14.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:320
Count of miRNA genes:255
Interacting mature miRNAs:261
Transcripts:ENST00000432771, ENST00000448984
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
11 51 94 60 219 47 60 7 42 2 42 177 146 1 209 18 426 48 5

Sequence


Ensembl Acc Id: ENST00000448984   ⟹   ENSP00000388299
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1190,031,106 - 90,042,025 (+)Ensembl
RefSeq Acc Id: NM_001195234   ⟹   NP_001182163
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381190,031,106 - 90,042,025 (+)NCBI
T2T-CHM13v2.01189,951,193 - 89,962,103 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017018126   ⟹   XP_016873615
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381190,035,208 - 90,042,025 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024448656   ⟹   XP_024304424
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381190,035,212 - 90,073,531 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054369639   ⟹   XP_054225614
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01189,955,295 - 89,962,103 (+)NCBI
RefSeq Acc Id: XM_054369640   ⟹   XP_054225615
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01189,955,299 - 89,993,609 (+)NCBI
Ensembl Acc Id: ENSP00000388299   ⟸   ENST00000448984
RefSeq Acc Id: NP_001182163   ⟸   NM_001195234
- UniProtKB: Q9NS80 (UniProtKB/Swiss-Prot),   Q6DJV1 (UniProtKB/Swiss-Prot),   P0CI26 (UniProtKB/Swiss-Prot),   A0AVR9 (UniProtKB/Swiss-Prot),   A0AVR7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_054225614   ⟸   XM_054369639
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054225615   ⟸   XM_054369640
- Peptide Label: isoform X2
RefSeq Acc Id: XP_016873615   ⟸   XM_017018126
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024304424   ⟸   XM_024448656
- Peptide Label: isoform X2
- Sequence:
Protein Domains
B30.2/SPRY

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0CI26-F1-model_v2 AlphaFold P0CI26 1-452 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:38877 AgrOrtholog
COSMIC TRIM49C COSMIC
Ensembl Genes ENSG00000204449 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000448984 ENTREZGENE
  ENST00000448984.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.920 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
  Classic Zinc Finger UniProtKB/Swiss-Prot
GTEx ENSG00000204449 GTEx
HGNC ID HGNC:38877 ENTREZGENE
Human Proteome Map TRIM49C Human Proteome Map
InterPro B30.2/SPRY UniProtKB/Swiss-Prot
  B30.2/SPRY_sf UniProtKB/Swiss-Prot
  Butyrophylin_SPRY UniProtKB/Swiss-Prot
  ConA-like_dom_sf UniProtKB/Swiss-Prot
  SPRY_dom UniProtKB/Swiss-Prot
  TRIM/RBCC UniProtKB/Swiss-Prot
  Znf_B-box UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
KEGG Report hsa:642612 UniProtKB/Swiss-Prot
NCBI Gene TRIM49C ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM UniProtKB/Swiss-Prot
  TRIPARTITE MOTIF-CONTAINING PROTEIN 49-RELATED UniProtKB/Swiss-Prot
Pfam SPRY UniProtKB/Swiss-Prot
  zf-B_box UniProtKB/Swiss-Prot
  zf-C3HC4_4 UniProtKB/Swiss-Prot
PharmGKB PA166049036 PharmGKB
PRINTS BUTYPHLNCDUF UniProtKB/Swiss-Prot
PROSITE B302_SPRY UniProtKB/Swiss-Prot
  ZF_BBOX UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
SMART BBOX UniProtKB/Swiss-Prot
  RING UniProtKB/Swiss-Prot
  SPRY UniProtKB/Swiss-Prot
Superfamily-SCOP B-box zinc-binding domain UniProtKB/Swiss-Prot
  RING/U-box UniProtKB/Swiss-Prot
  SSF49899 UniProtKB/Swiss-Prot
UniProt A0AVR7 ENTREZGENE
  A0AVR9 ENTREZGENE
  P0CI26 ENTREZGENE
  Q6DJV1 ENTREZGENE
  Q9NS80 ENTREZGENE
  TR49C_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary A0AVR7 UniProtKB/Swiss-Prot
  A0AVR9 UniProtKB/Swiss-Prot
  Q6DJV1 UniProtKB/Swiss-Prot
  Q9NS80 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-12-21 TRIM49C  tripartite motif containing 49C  LOC105378955  tripartite motif-containing protein 43B  Data Merged 737654 PROVISIONAL
2012-05-29 TRIM49C  tripartite motif containing 49C  TRIM49L2  tripartite motif containing 49-like 2  Symbol and/or name change 5135510 APPROVED
2011-07-27 TRIM49L2  tripartite motif containing 49-like 2  TRIM49L2  tripartite motif-containing 49-like 2  Symbol and/or name change 5135510 APPROVED