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Gene: MYCBP2 (MYC binding protein 2) Homo sapiens
Symbol: MYCBP2
Name: MYC binding protein 2
Description: Exhibits GTPase binding activity; ubiquitin protein ligase activity; and zinc ion binding activity. Involved in circadian regulation of gene expression; positive regulation of protein ubiquitination; and protein ubiquitination. Localizes to the nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686M08244; E3 ubiquitin-protein ligase MYCBP2; FLJ10106; FLJ13826; FLJ21597; FLJ21646; Highwire; KIAA0916; MYC binding protein 2, E3 ubiquitin protein ligase; myc-binding protein 2; Myc-bp2; PAM; pam/highwire/rpm-1 protein; PAM/Highwire/RPM-1 protein 1; Phr; PHR1; probable E3 ubiquitin-protein ligase MYCBP2; protein associated with Myc; RING-type E3 ubiquitin transferase MYCBP2
Mus musculus (house mouse) : Mycbp2 (MYC binding protein 2, E3 ubiquitin protein ligase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mycbp2 (MYC binding protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mycbp2 (MYC binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MYCBP2 (MYC binding protein 2)
Canis lupus familiaris (dog) : MYCBP2 (MYC binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mycbp2 (MYC binding protein 2)
Sus scrofa (pig) : MYCBP2 (MYC binding protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381377,044,657 - 77,327,098 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371377,618,792 - 77,901,177 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361376,516,793 - 76,799,178 (-)NCBINCBI36hg18NCBI36
Build 341376,516,793 - 76,799,178NCBI
Celera1358,516,778 - 58,799,215 (-)NCBI
Cytogenetic Map13q22.3NCBI
HuRef1358,316,505 - 58,599,005 (-)NCBIHuRef
CHM1_11377,586,683 - 77,869,027 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MYCBP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323830
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.