RNF150 (ring finger protein 150) - Rat Genome Database
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Gene: RNF150 (ring finger protein 150) Homo sapiens
Analyze
Symbol: RNF150
Name: ring finger protein 150
RGD ID: 1322589
Description: Predicted to have ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to localize to cytoplasm; INTERACTS WITH 17beta-estradiol; 2-methylcholine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC125502
Orthologs:
Mus musculus (house mouse) : Rnf150 (ring finger protein 150)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rnf150 (ring finger protein 150)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf150 (ring finger protein 150)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF150 (ring finger protein 150)
Canis lupus familiaris (dog) : RNF150 (ring finger protein 150)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf150 (ring finger protein 150)
Sus scrofa (pig) : RNF150 (ring finger protein 150)
Chlorocebus sabaeus (African green monkey) : RNF150 (ring finger protein 150)
Heterocephalus glaber (naked mole-rat) : Rnf150 (ring finger protein 150)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4140,859,807 - 141,212,877 (-)EnsemblGRCh38hg38GRCh38
GRCh384140,859,807 - 141,212,858 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374141,786,708 - 142,054,630 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364142,006,175 - 142,274,066 (-)NCBINCBI36hg18NCBI36
Celera4139,117,485 - 139,385,356 (-)NCBI
Cytogenetic Map4q31.21NCBI
HuRef4137,516,392 - 137,784,285 (-)NCBIHuRef
CHM1_14141,763,725 - 142,032,048 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10574462   PMID:12477932   PMID:14702039   PMID:15489334   PMID:15815621   PMID:19322201   PMID:19690564   PMID:20379614   PMID:21873635   PMID:22658674   PMID:23144326   PMID:25609945  
PMID:28514442   PMID:29507755   PMID:29643511   PMID:32296183  


Genomics

Comparative Map Data
RNF150
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4140,859,807 - 141,212,877 (-)EnsemblGRCh38hg38GRCh38
GRCh384140,859,807 - 141,212,858 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374141,786,708 - 142,054,630 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364142,006,175 - 142,274,066 (-)NCBINCBI36hg18NCBI36
Celera4139,117,485 - 139,385,356 (-)NCBI
Cytogenetic Map4q31.21NCBI
HuRef4137,516,392 - 137,784,285 (-)NCBIHuRef
CHM1_14141,763,725 - 142,032,048 (-)NCBICHM1_1
Rnf150
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39883,589,889 - 83,817,900 (+)NCBI
GRCm38882,863,266 - 83,091,271 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl882,863,356 - 83,091,268 (+)EnsemblGRCm38mm10GRCm38
MGSCv37885,387,255 - 85,615,170 (+)NCBIGRCm37mm9NCBIm37
MGSCv36885,742,822 - 85,974,276 (+)NCBImm8
Celera887,238,149 - 87,365,916 (+)NCBICelera
Cytogenetic Map8C2NCBI
Rnf150
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01924,044,210 - 24,264,508 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1924,044,103 - 24,265,444 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01935,023,098 - 35,245,889 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41926,737,910 - 26,962,470 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11926,966,663 - 26,967,290 (-)NCBI
Celera1924,548,378 - 24,768,444 (-)NCBICelera
Cytogenetic Map19q11NCBI
Rnf150
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554712,027,027 - 2,252,734 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554712,026,779 - 2,255,816 (+)NCBIChiLan1.0ChiLan1.0
RNF150
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14144,535,446 - 144,798,256 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4144,536,761 - 144,797,587 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04133,220,007 - 133,494,884 (-)NCBIMhudiblu_PPA_v0panPan3
RNF150
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl191,817,164 - 2,053,846 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1191,817,199 - 2,053,632 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rnf150
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365356,823,946 - 7,039,354 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF150
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl886,088,013 - 86,332,935 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1886,087,938 - 86,330,418 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2891,560,067 - 91,695,534 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF150
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1787,789,859 - 88,052,237 (-)NCBI
Rnf150
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624853291,946 - 549,392 (-)NCBI

Position Markers
D4S1565  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,860,699 - 141,860,866UniSTSGRCh37
GRCh374141,860,735 - 141,860,886UniSTSGRCh37
Build 364142,080,149 - 142,080,316RGDNCBI36
Celera4139,191,447 - 139,191,602RGD
Celera4139,191,483 - 139,191,622UniSTS
Cytogenetic Map4q31.21UniSTS
HuRef4137,590,302 - 137,590,441UniSTS
HuRef4137,590,266 - 137,590,421UniSTS
Marshfield Genetic Map4143.84UniSTS
Marshfield Genetic Map4143.84RGD
Genethon Genetic Map4143.1UniSTS
TNG Radiation Hybrid Map485759.0UniSTS
Stanford-G3 RH Map47803.0UniSTS
Whitehead-YAC Contig Map4 UniSTS
NCBI RH Map41453.7UniSTS
GeneMap99-G3 RH Map47728.0UniSTS
D4S192  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,860,826 - 141,861,006UniSTSGRCh37
GRCh374141,860,744 - 141,860,846UniSTSGRCh37
GRCh374141,860,915 - 141,861,116UniSTSGRCh37
Celera4139,191,562 - 139,191,742UniSTS
Celera4139,191,651 - 139,191,852UniSTS
Celera4139,191,492 - 139,191,582UniSTS
Cytogenetic Map4q31.21UniSTS
HuRef4137,590,470 - 137,590,671UniSTS
HuRef4137,590,311 - 137,590,401UniSTS
HuRef4137,590,381 - 137,590,561UniSTS
Marshfield Genetic Map4143.31RGD
TNG Radiation Hybrid Map485751.0UniSTS
deCODE Assembly Map4138.17UniSTS
Stanford-G3 RH Map47799.0UniSTS
Whitehead-YAC Contig Map4 UniSTS
NCBI RH Map41455.1UniSTS
RH41779  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,786,727 - 141,786,939UniSTSGRCh37
Build 364142,006,177 - 142,006,389RGDNCBI36
Celera4139,117,487 - 139,117,699RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,516,394 - 137,516,606UniSTS
GeneMap99-GB4 RH Map4615.19UniSTS
NCBI RH Map41486.9UniSTS
SHGC-50203  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,820,376 - 141,820,493UniSTSGRCh37
Build 364142,039,826 - 142,039,943RGDNCBI36
Celera4139,151,133 - 139,151,250RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,550,040 - 137,550,157UniSTS
TNG Radiation Hybrid Map485715.0UniSTS
G16704  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,985,862 - 141,986,013UniSTSGRCh37
Build 364142,205,312 - 142,205,463RGDNCBI36
Celera4139,316,604 - 139,316,755RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,715,510 - 137,715,661UniSTS
SHGC-80055  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,809,801 - 141,810,101UniSTSGRCh37
Build 364142,029,251 - 142,029,551RGDNCBI36
Celera4139,140,555 - 139,140,855RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,539,462 - 137,539,762UniSTS
TNG Radiation Hybrid Map485698.0UniSTS
RH119954  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,980,367 - 141,980,493UniSTSGRCh37
Build 364142,199,817 - 142,199,943RGDNCBI36
Celera4139,311,109 - 139,311,235RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,710,013 - 137,710,139UniSTS
TNG Radiation Hybrid Map485841.0UniSTS
RH122720  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,792,688 - 141,792,976UniSTSGRCh37
Build 364142,012,138 - 142,012,426RGDNCBI36
Celera4139,123,446 - 139,123,734RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,522,353 - 137,522,641UniSTS
TNG Radiation Hybrid Map485705.0UniSTS
SHGC-141842  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374142,051,429 - 142,051,712UniSTSGRCh37
Build 364142,270,879 - 142,271,162RGDNCBI36
Celera4139,382,169 - 139,382,452RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,781,098 - 137,781,381UniSTS
TNG Radiation Hybrid Map485859.0UniSTS
SHGC-155320  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,995,355 - 141,995,677UniSTSGRCh37
Build 364142,214,805 - 142,215,127RGDNCBI36
Celera4139,326,097 - 139,326,419RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,725,004 - 137,725,326UniSTS
TNG Radiation Hybrid Map485834.0UniSTS
G34522  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,928,117 - 141,928,302UniSTSGRCh37
Build 364142,147,567 - 142,147,752RGDNCBI36
Celera4139,258,857 - 139,259,042RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,657,761 - 137,657,946UniSTS
SHGC-23687  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,928,117 - 141,928,375UniSTSGRCh37
Build 364142,147,567 - 142,147,825RGDNCBI36
Celera4139,258,857 - 139,259,115RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,657,761 - 137,658,019UniSTS
TNG Radiation Hybrid Map485820.0UniSTS
STS-N22353  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,786,752 - 141,786,879UniSTSGRCh37
Build 364142,006,202 - 142,006,329RGDNCBI36
Celera4139,117,512 - 139,117,639RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,516,419 - 137,516,546UniSTS
TNG Radiation Hybrid Map485698.0UniSTS
GeneMap99-GB4 RH Map4615.93UniSTS
NCBI RH Map41485.2UniSTS
D4S1297  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,892,285 - 141,892,436UniSTSGRCh37
Build 364142,111,735 - 142,111,886RGDNCBI36
Celera4139,223,028 - 139,223,179RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,621,836 - 137,621,987UniSTS
TNG Radiation Hybrid Map485791.0UniSTS
D4S2812  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,846,874 - 141,847,006UniSTSGRCh37
Build 364142,066,324 - 142,066,456RGDNCBI36
Celera4139,177,610 - 139,177,742RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,576,473 - 137,576,605UniSTS
Whitehead-YAC Contig Map4 UniSTS
D4S3314  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374141,820,335 - 141,820,467UniSTSGRCh37
Build 364142,039,785 - 142,039,917RGDNCBI36
Celera4139,151,092 - 139,151,224RGD
Cytogenetic Map4q31.21UniSTS
HuRef4137,549,999 - 137,550,131UniSTS
D4S1565  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4q31.21UniSTS
TNG Radiation Hybrid Map485759.0UniSTS
Stanford-G3 RH Map47803.0UniSTS
NCBI RH Map41453.7UniSTS
GeneMap99-G3 RH Map47728.0UniSTS
D4S192  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4q31.21UniSTS
TNG Radiation Hybrid Map485759.0UniSTS
Stanford-G3 RH Map47763.0UniSTS
NCBI RH Map41442.1UniSTS
D4S192  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4q21-q31UniSTS
Cytogenetic Map4q31.21UniSTS
TNG Radiation Hybrid Map485755.0UniSTS
deCODE Assembly Map4138.17UniSTS
Whitehead-YAC Contig Map4 UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:6467
Count of miRNA genes:1225
Interacting mature miRNAs:1545
Transcripts:ENST00000306799, ENST00000379512, ENST00000420921, ENST00000506101, ENST00000507500, ENST00000515057, ENST00000515673
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1331 543 473 43 85 11 441 877 733 76 525 110 34 152 313
Low 851 1654 960 294 478 166 3783 1266 2946 272 892 1384 134 1 1051 2418 3 2
Below cutoff 150 698 261 257 745 256 127 49 53 57 24 88 2 1 57 1

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000306799   ⟹   ENSP00000304321
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl4140,865,571 - 141,133,462 (-)Ensembl
RefSeq Acc Id: ENST00000420921   ⟹   ENSP00000394581
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl4140,865,571 - 141,212,877 (-)Ensembl
RefSeq Acc Id: ENST00000506101   ⟹   ENSP00000425947
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl4140,865,576 - 141,132,637 (-)Ensembl
RefSeq Acc Id: ENST00000507500   ⟹   ENSP00000425568
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl4140,911,053 - 141,133,049 (-)Ensembl
RefSeq Acc Id: ENST00000515057
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl4140,944,549 - 140,967,870 (-)Ensembl
RefSeq Acc Id: ENST00000515673   ⟹   ENSP00000425840
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl4140,859,807 - 141,133,469 (-)Ensembl
RefSeq Acc Id: NM_020724   ⟹   NP_065775
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384140,859,807 - 141,133,469 (-)NCBI
GRCh374141,786,708 - 142,054,630 (-)NCBI
Build 364142,006,175 - 142,274,066 (-)NCBI Archive
Celera4139,117,485 - 139,385,356 (-)RGD
HuRef4137,516,392 - 137,784,285 (-)RGD
CHM1_14141,763,725 - 142,032,048 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005263150   ⟹   XP_005263207
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384140,859,807 - 141,134,633 (-)NCBI
GRCh374141,786,708 - 142,054,630 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011532147   ⟹   XP_011530449
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384140,859,807 - 141,109,922 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011532148   ⟹   XP_011530450
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384140,859,807 - 141,212,858 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017008475   ⟹   XP_016863964
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384140,859,807 - 141,109,922 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017008476   ⟹   XP_016863965
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384140,859,807 - 140,977,321 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_065775   ⟸   NM_020724
- Peptide Label: precursor
- UniProtKB: Q9ULK6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005263207   ⟸   XM_005263150
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011530450   ⟸   XM_011532148
- Peptide Label: isoform X3
- UniProtKB: Q9ULK6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011530449   ⟸   XM_011532147
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_016863964   ⟸   XM_017008475
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_016863965   ⟸   XM_017008476
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSP00000304321   ⟸   ENST00000306799
RefSeq Acc Id: ENSP00000425947   ⟸   ENST00000506101
RefSeq Acc Id: ENSP00000425568   ⟸   ENST00000507500
RefSeq Acc Id: ENSP00000394581   ⟸   ENST00000420921
RefSeq Acc Id: ENSP00000425840   ⟸   ENST00000515673
Protein Domains
PA   RING-type

Promoters
RGD ID:6868546
Promoter ID:EPDNEW_H7437
Type:initiation region
Name:RNF150_3
Description:ring finger protein 150
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H7438  EPDNEW_H7439  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh384141,132,816 - 141,132,876EPDNEW
RGD ID:6868548
Promoter ID:EPDNEW_H7438
Type:initiation region
Name:RNF150_1
Description:ring finger protein 150
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H7437  EPDNEW_H7439  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh384141,133,469 - 141,133,529EPDNEW
RGD ID:6868592
Promoter ID:EPDNEW_H7439
Type:multiple initiation site
Name:RNF150_2
Description:ring finger protein 150
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H7437  EPDNEW_H7438  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh384141,212,900 - 141,212,960EPDNEW
RGD ID:6802568
Promoter ID:HG_KWN:49186
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   Jurkat
Transcripts:NM_020724,   UC003IIP.1,   UC010IOK.1
Position:
Human AssemblyChrPosition (strand)Source
Build 364142,273,829 - 142,274,329 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 4q28.2-31.21(chr4:128119872-142431375)x1 copy number loss See cases [RCV000051056] Chr4:128119872..142431375 [GRCh38]
Chr4:129041027..143352528 [GRCh37]
Chr4:129260477..143571978 [NCBI36]
Chr4:4q28.2-31.21
pathogenic
GRCh38/hg38 4q26-35.2(chr4:118065569-190042639)x3 copy number gain See cases [RCV000051785] Chr4:118065569..190042639 [GRCh38]
Chr4:118986724..190828225 [GRCh37]
Chr4:119206172..191200788 [NCBI36]
Chr4:4q26-35.2
pathogenic
GRCh38/hg38 4q27-35.2(chr4:121518223-190062270)x3 copy number gain See cases [RCV000051786] Chr4:121518223..190062270 [GRCh38]
Chr4:122439378..190828225 [GRCh37]
Chr4:122658828..191220419 [NCBI36]
Chr4:4q27-35.2
pathogenic
GRCh38/hg38 4q31.21-31.3(chr4:140876253-152186578)x3 copy number gain See cases [RCV000051787] Chr4:140876253..152186578 [GRCh38]
Chr4:141797407..153107730 [GRCh37]
Chr4:142016857..153327180 [NCBI36]
Chr4:4q31.21-31.3
pathogenic
GRCh38/hg38 4q22.2-32.3(chr4:92913386-165299707)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051775]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051775]|See cases [RCV000051775] Chr4:92913386..165299707 [GRCh38]
Chr4:93834537..166220859 [GRCh37]
Chr4:94053560..166440309 [NCBI36]
Chr4:4q22.2-32.3
pathogenic
GRCh38/hg38 4q26-31.21(chr4:116630862-145429900)x1 copy number loss See cases [RCV000053321] Chr4:116630862..145429900 [GRCh38]
Chr4:117552018..146351052 [GRCh37]
Chr4:117771466..146570502 [NCBI36]
Chr4:4q26-31.21
pathogenic
GRCh38/hg38 4q31.21(chr4:140605955-144317039)x1 copy number loss See cases [RCV000053323] Chr4:140605955..144317039 [GRCh38]
Chr4:141527109..145238191 [GRCh37]
Chr4:141746559..145457641 [NCBI36]
Chr4:4q31.21
pathogenic
NM_020724.1(RNF150):c.623C>T (p.Ser208Leu) single nucleotide variant Malignant melanoma [RCV000066280] Chr4:140967735 [GRCh38]
Chr4:141888889 [GRCh37]
Chr4:142108339 [NCBI36]
Chr4:4q31.21
not provided
GRCh38/hg38 4q31.1-35.2(chr4:138510532-189963195)x3 copy number gain See cases [RCV000136810] Chr4:138510532..189963195 [GRCh38]
Chr4:139431686..190828225 [GRCh37]
Chr4:139651136..191121344 [NCBI36]
Chr4:4q31.1-35.2
pathogenic
GRCh38/hg38 4q28.3-35.2(chr4:131985253-190095391)x3 copy number gain See cases [RCV000137721] Chr4:131985253..190095391 [GRCh38]
Chr4:132906408..190828225 [GRCh37]
Chr4:133125858..191250527 [NCBI36]
Chr4:4q28.3-35.2
pathogenic|likely benign
GRCh38/hg38 4q28.1-35.1(chr4:125432943-185761887)x3 copy number gain See cases [RCV000138578] Chr4:125432943..185761887 [GRCh38]
Chr4:126354098..186683041 [GRCh37]
Chr4:126573548..186920035 [NCBI36]
Chr4:4q28.1-35.1
pathogenic|likely benign
GRCh38/hg38 4q28.3-35.2(chr4:134935616-190036318)x3 copy number gain See cases [RCV000143559] Chr4:134935616..190036318 [GRCh38]
Chr4:135856771..190957473 [GRCh37]
Chr4:136076221..191194467 [NCBI36]
Chr4:4q28.3-35.2
pathogenic
NC_000004.12:g.141140388T>C single nucleotide variant Lung cancer [RCV000094165] Chr4:141140388 [GRCh38]
Chr4:142061542 [GRCh37]
Chr4:4q31.21
uncertain significance
GRCh37/hg19 4q28.3-35.1(chr4:136912336-184253252)x3 copy number gain See cases [RCV000240245] Chr4:136912336..184253252 [GRCh37]
Chr4:4q28.3-35.1
pathogenic
GRCh37/hg19 4q26-35.2(chr4:119437495-190904301)x3 copy number gain See cases [RCV000240392] Chr4:119437495..190904301 [GRCh37]
Chr4:4q26-35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4q25-35.2(chr4:109199664-189752726)x3 copy number gain See cases [RCV000511945] Chr4:109199664..189752726 [GRCh37]
Chr4:4q25-35.2
pathogenic
GRCh37/hg19 4q22.1-35.2(chr4:93071152-190957473)x3 copy number gain See cases [RCV000510970] Chr4:93071152..190957473 [GRCh37]
Chr4:4q22.1-35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4q31.21(chr4:141663149-143163452)x1 copy number loss not provided [RCV000682460] Chr4:141663149..143163452 [GRCh37]
Chr4:4q31.21
uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4q28.3-31.21(chr4:134054911-142601496)x1 copy number loss not provided [RCV000847693] Chr4:134054911..142601496 [GRCh37]
Chr4:4q28.3-31.21
uncertain significance
GRCh37/hg19 4q31.1-31.21(chr4:140522019-146347867)x1 copy number loss not provided [RCV000848032] Chr4:140522019..146347867 [GRCh37]
Chr4:4q31.1-31.21
uncertain significance
GRCh37/hg19 4q28.1-35.1(chr4:124873497-185278662)x3 copy number gain not provided [RCV000849686] Chr4:124873497..185278662 [GRCh37]
Chr4:4q28.1-35.1
pathogenic
GRCh37/hg19 4q31.1-31.21(chr4:141176846-142078534)x3 copy number gain not provided [RCV000847175] Chr4:141176846..142078534 [GRCh37]
Chr4:4q31.1-31.21
uncertain significance
GRCh37/hg19 4q31.1-31.21(chr4:139531815-146095109)x1 copy number loss not provided [RCV001005600] Chr4:139531815..146095109 [GRCh37]
Chr4:4q31.1-31.21
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:23138 AgrOrtholog
COSMIC RNF150 COSMIC
Ensembl Genes ENSG00000170153 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000304321 UniProtKB/Swiss-Prot
  ENSP00000394581 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000425568 UniProtKB/Swiss-Prot
  ENSP00000425840 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000425947 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENST00000306799 UniProtKB/Swiss-Prot
  ENST00000420921 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000506101 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000507500 UniProtKB/Swiss-Prot
  ENST00000515673 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000170153 GTEx
HGNC ID HGNC:23138 ENTREZGENE
Human Proteome Map RNF150 Human Proteome Map
InterPro PA_domain UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:57484 UniProtKB/Swiss-Prot
NCBI Gene 57484 ENTREZGENE
Pfam PF02225 UniProtKB/Swiss-Prot
  zf-RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134918555 PharmGKB
PROSITE ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Hs.659104 ENTREZGENE
UniProt D6RIE5_HUMAN UniProtKB/TrEMBL
  Q9ULK6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3T1D0 UniProtKB/Swiss-Prot
  Q6ZNW6 UniProtKB/Swiss-Prot