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Gene: LTN1 (listerin E3 ubiquitin protein ligase 1) Homo sapiens
Symbol: LTN1
Name: listerin E3 ubiquitin protein ligase 1
RGD ID: 1322590
Description: Predicted to have ribosomal large subunit binding activity and ubiquitin protein ligase activity. Predicted to be involved in rescue of stalled ribosome and ribosome-associated ubiquitin-dependent protein catabolic process. Predicted to localize to RQC complex and cytosol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C21orf10; C21orf98; E3 ubiquitin-protein ligase listerin; FLJ11053; KIAA0714; RING finger protein 160; RING-type E3 ubiquitin transferase listerin; RNF160; zinc finger protein 294; ZNF294
Mus musculus (house mouse) : Ltn1 (listerin E3 ubiquitin protein ligase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ltn1 (listerin E3 ubiquitin protein ligase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ltn1 (listerin E3 ubiquitin protein ligase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LTN1 (listerin E3 ubiquitin protein ligase 1)
Canis lupus familiaris (dog) : LTN1 (listerin E3 ubiquitin protein ligase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ltn1 (listerin E3 ubiquitin protein ligase 1)
Sus scrofa (pig) : LTN1 (listerin E3 ubiquitin protein ligase 1)
Chlorocebus sabaeus (African green monkey) : LTN1 (listerin E3 ubiquitin protein ligase 1)
Heterocephalus glaber (naked mole-rat) : Ltn1 (listerin E3 ubiquitin protein ligase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2128,928,144 - 28,992,956 (-)EnsemblGRCh38hg38GRCh38
GRCh382128,928,144 - 28,992,988 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372130,300,466 - 30,365,277 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362129,222,337 - 29,287,095 (-)NCBINCBI36hg18NCBI36
Build 342129,222,336 - 29,287,095NCBI
Celera2115,483,199 - 15,548,010 (-)NCBI
Cytogenetic Map21q21.3NCBI
HuRef2115,705,158 - 15,769,951 (-)NCBIHuRef
CHM1_12129,862,811 - 29,927,627 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LTN1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1322590
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.