regulation of body fluid levels - Ontology Report

GO_REF:0000107

NCBI chr20:109,747,883...109,954,936
Ensembl chr20:109,746,925...109,890,777

HEG1

heart development protein with EGF like domains 1

acts_upstream_of_or_within
involved_in

(PMID:19151727)

PMID:19151727

GO_REF:0000107

NCBI chr22:55,782,039...55,874,679
Ensembl chr22:55,809,901...55,871,402

PDSS2

decaprenyl diphosphate synthase subunit 2

acts_upstream_of_or_within
involved_in

(PMID:5098070)

PMID:5098070

GO_REF:0000107

NCBI chr13:66,405,014...66,704,559
Ensembl chr13:66,405,521...66,704,696

SCNN1A

sodium channel epithelial 1 subunit alpha

NCBI chr11:6,384,073...6,418,620
Ensembl chr11:6,383,956...6,416,337

activation of blood coagulation via clotting cascade

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANO6

anoctamin 6

involved_in

GO_REF:0000107

NCBI chr11:41,420,206...41,633,323
Ensembl chr11:41,419,901...41,633,347

von Willebrand factor

acts_upstream_of_or_within

(PMID:30573509)

PMID:30573509

NCBI chr11:5,994,499...6,176,949
Ensembl chr11:5,994,039...6,162,260

blood coagulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANGPT1

angiopoietin 1

involved_in

GO_REF:0000002

NCBI chr 8:102,020,346...102,268,443

ANGPT2

angiopoietin 2

involved_in

GO_REF:0000002

NCBI chr 8:6,283,619...6,345,320
Ensembl chr 8:6,280,584...6,344,729

angiopoietin 4

involved_in

GO_REF:0000002

NCBI chr 2:55,619,463...55,654,843
Ensembl chr 2:55,620,694...55,654,001

angiopoietin like 1

involved_in

GO_REF:0000002

NCBI chr25:50,468,283...50,489,283
Ensembl chr25:50,468,826...50,490,343

ANGPTL2

angiopoietin like 2

involved_in

GO_REF:0000002

NCBI chr12:11,013,553...11,049,254
Ensembl chr12:11,013,598...11,050,522

ANGPTL3

angiopoietin like 3

involved_in

GO_REF:0000002

NCBI chr20:70,452,771...70,461,590
Ensembl chr20:70,449,227...70,460,469

ANGPTL4

angiopoietin like 4

involved_in

GO_REF:0000002

NCBI chr 6:7,719,359...7,728,799
Ensembl chr 6:7,719,400...7,729,302

angiopoietin like 6

involved_in

GO_REF:0000002

Ensembl chr 6:9,160,144...9,164,609

ANGPTL7

angiopoietin like 7

involved_in

GO_REF:0000002

NCBI chr20:120,589,968...120,598,751
Ensembl chr20:120,589,812...120,597,017

ANO6

anoctamin 6

involved_in

(PMID:23021219)

PMID:23021219

NCBI chr11:41,420,206...41,633,323
Ensembl chr11:41,419,901...41,633,347

AP3B1

adaptor related protein complex 3 subunit beta 1

acts_upstream_of_or_within
involved_in

(PMID:6696991)

GO_REF:0000107

NCBI chr 4:72,225,658...72,524,971
Ensembl chr 4:72,225,599...72,524,933

BLOC1S3

biogenesis of lysosomal organelles complex 1 subunit 3

acts_upstream_of_or_within
involved_in

(PMID:15265785)

PMID:15265785

GO_REF:0000107

NCBI chr 6:38,623,639...38,642,217
Ensembl chr 6:38,639,659...38,640,261

BLOC1S6

biogenesis of lysosomal organelles complex 1 subunit 6

acts_upstream_of_or_within
involved_in

(PMID:6696991)

GO_REF:0000107

NCBI chr26:37,605,891...37,622,302
Ensembl chr26:37,604,412...37,622,083

COMP

cartilage oligomeric matrix protein

involved_in
acts_upstream_of_or_within

(PMID:26045608)

PMID:26045608

GO_REF:0000107

NCBI chr 6:17,246,617...17,255,561
Ensembl chr 6:17,246,762...17,255,126

DTNBP1

dystrobrevin binding protein 1

involved_in
acts_upstream_of_or_within

(PMID:1936982)

PMID:1936982

GO_REF:0000107

NCBI chr17:56,500,523...56,650,925
Ensembl chr17:56,500,574...56,651,491

ENPP4

ectonucleotide pyrophosphatase/phosphodiesterase 4

involved_in

GO_REF:0000043

NCBI chr17:26,102,687...26,117,142
Ensembl chr17:26,102,510...26,117,080

F10

coagulation factor X

involved_in

GO_REF:0000002 GO_REF:0000043

NCBI chr 3:91,125,097...91,154,000
Ensembl chr 3:91,124,766...91,157,376

F11

coagulation factor XI

involved_in

UniProt
Ensembl

GO_REF:0000043 GO_REF:0000107

NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155

coagulation factor XII

acts_upstream_of_or_within
involved_in

MGI
UniProt
Ensembl
TreeGrafter

(PMID:15351846)

PMID:15351846

GO_REF:0000043 GO_REF:0000107 GO_REF:0000118

NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298

F13A1

coagulation factor XIII A chain

acts_upstream_of_or_within
involved_in

(PMID:12529747)

PMID:12529747

GO_REF:0000107

NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040

F13B

coagulation factor XIII B chain

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973

coagulation factor II thrombin receptor

involved_in

GO_REF:0000002 GO_REF:0000043

NCBI chr 4:70,992,406...71,010,512
Ensembl chr 4:70,992,477...71,009,456

F2RL1

F2R like trypsin receptor 1

involved_in

GO_REF:0000002

NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005

F2RL2

coagulation factor II thrombin receptor like 2

involved_in

GO_REF:0000002

NCBI chr 4:70,887,979...70,895,419
Ensembl chr 4:70,886,113...70,895,113

F2RL3

F2R like thrombin or trypsin receptor 3

involved_in

GO_REF:0000002

NCBI chr 6:15,397,552...15,400,708

coagulation factor III, tissue factor

involved_in

InterPro
UniProt
Ensembl

GO_REF:0000002 GO_REF:0000043 GO_REF:0000107

NCBI chr20:38,726,690...38,738,457
Ensembl chr20:38,726,798...38,739,408

coagulation factor V

acts_upstream_of_or_within
involved_in

(PMID:12816857), (PMID:12855561)
(PMID:8900278)

PMID:8900278 PMID:12816857 PMID:12855561

GO_REF:0000107

NCBI chr25:59,465,610...59,539,022
Ensembl chr25:59,466,378...59,538,872

coagulation factor VII

involved_in
acts_upstream_of_or_within

(PMID:9384381)

UniProt
MGI
Ensembl

PMID:9384381

GO_REF:0000043 GO_REF:0000107

NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327

coagulation factor IX

involved_in
acts_upstream_of_or_within

InterPro
TreeGrafter
MGI
UniProt
Ensembl

(PMID:15178576)

PMID:15178576

GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118

NCBI chr X:114,618,397...114,650,827
Ensembl chr X:114,618,639...114,651,365

fibrinogen alpha chain

involved_in
acts_upstream_of_or_within

(PMID:10930441)

UniProt
MGI
InterPro
Ensembl

PMID:10930441

GO_REF:0000002 GO_REF:0000043 GO_REF:0000107

NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405

fibrinogen beta chain

involved_in

UniProt
InterPro

GO_REF:0000002 GO_REF:0000043

NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662

fibrinogen gamma chain

involved_in

GO_REF:0000002 GO_REF:0000043

NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111

fibrinogen like 1

involved_in

GO_REF:0000002

NCBI chr 8:15,962,625...16,016,118
Ensembl chr 8:15,962,053...15,982,336

GAS6

growth arrest specific 6

involved_in

GO_REF:0000107

Ensembl chr 3:91,720,882...91,738,069

glycoprotein Ib platelet subunit alpha

acts_upstream_of_or_within
involved_in

PMID:18187573 PMID:20650879 PMID:21037087

(PMID:21037087)
(PMID:18187573)
(PMID:20650879), (PMID:21037087)

MGI
ComplexPortal

NCBI chr16:4,412,693...4,415,841

glycoprotein Ib platelet subunit alpha

involved_in

GO_REF:0000107

Ensembl chr16:4,413,307...4,415,475

GP1BB

glycoprotein Ib platelet subunit beta

involved_in

(PMID:18187573)

PMID:18187573

NCBI chr19:6,020,618...6,021,646

glycoprotein V platelet

involved_in

(PMID:18187573)

PMID:18187573

NCBI chr15:88,491,781...88,495,601
Ensembl chr15:88,492,336...88,494,018

GP9

glycoprotein IX platelet

involved_in

Ensembl
UniProt

GO_REF:0000043 GO_REF:0000107

NCBI chr22:52,000,620...52,013,570
Ensembl chr22:52,000,758...52,001,291

HGFAC

HGF activator

involved_in

InterPro
TreeGrafter

GO_REF:0000002 GO_REF:0000118

NCBI chr27:45,283,213...45,290,922
Ensembl chr27:45,283,206...45,290,644

HNF4A

hepatocyte nuclear factor 4 alpha

involved_in

GO_REF:0000107

NCBI chr 2:19,390,870...19,466,300
Ensembl chr 2:19,388,891...19,421,664

HPS1

HPS1 biogenesis of lysosomal organelles complex 3 subunit 1

acts_upstream_of_or_within

(PMID:6696991)

NCBI chr 9:91,575,408...91,606,514
Ensembl chr 9:91,576,600...91,604,972

HPS4

HPS4 biogenesis of lysosomal organelles complex 3 subunit 2

involved_in
acts_upstream_of_or_within

(PMID:6696991)

GO_REF:0000107

NCBI chr19:9,356,868...9,387,847
Ensembl chr19:9,356,145...9,386,254

HPS5

HPS5 biogenesis of lysosomal organelles complex 2 subunit 2

involved_in
acts_upstream_of_or_within

(PMID:6696991)

GO_REF:0000107

NCBI chr 1:46,620,544...46,665,334
Ensembl chr 1:46,619,914...46,664,126

HPS6

HPS6 biogenesis of lysosomal organelles complex 2 subunit 3

involved_in
acts_upstream_of_or_within

(PMID:6696991)

UniProt
Ensembl
MGI

GO_REF:0000104 GO_REF:0000107

NCBI chr 9:95,098,879...95,101,643
Ensembl chr 9:95,099,095...95,101,422

histidine rich glycoprotein

involved_in

GO_REF:0000043

NCBI chr15:2,753,819...2,766,946
Ensembl chr15:2,753,810...2,766,478

KLKB1

kallikrein B1

involved_in

GO_REF:0000043

NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187

LNPK

lunapark, ER junction formation factor

involved_in
acts_upstream_of_or_within

(PMID:8835524)

PMID:8835524

GO_REF:0000107

NCBI chr10:61,498,749...61,575,166
Ensembl chr10:61,499,617...61,574,794

LOC103214855

growth arrest-specific protein 6

acts_upstream_of_or_within

(PMID:15184064)

PMID:15184064

NCBI chr 3:91,720,871...91,762,712

prothrombin

involved_in

GO_REF:0000002 GO_REF:0000043

NCBI chr 1:18,589,658...18,627,459
Ensembl chr 1:18,620,215...18,627,511
Ensembl chr 1:18,620,215...18,627,511

LYST

lysosomal trafficking regulator

acts_upstream_of_or_within

(PMID:6696991)

NCBI chr25:72,827,997...73,048,645
Ensembl chr25:72,828,006...72,991,970

MPIG6B

megakaryocyte and platelet inhibitory receptor G6b

acts_upstream_of_or_within
involved_in

(PMID:23112346)

PMID:23112346

GO_REF:0000107 GO_REF:0000118

NCBI chr17:40,297,946...40,300,442
Ensembl chr17:40,298,473...40,300,174

NBEAL2

neurobeachin like 2

acts_upstream_of_or_within

(PMID:23863626)

PMID:23863626

NCBI chr22:8,385,109...8,414,553
Ensembl chr22:8,385,229...8,414,655

P2RY12

purinergic receptor P2Y12

involved_in

GO_REF:0000002

NCBI chr15:39,315,140...39,361,614
Ensembl chr15:39,359,612...39,360,637

PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

involved_in
acts_upstream_of_or_within

(PMID:8835524)

PMID:8835524

GO_REF:0000107

NCBI chr 9:81,102,477...81,191,951
Ensembl chr 9:81,102,520...81,190,230

plasminogen

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644

PROC

protein C, inactivator of coagulation factors Va and VIIIa

involved_in

UniProt
InterPro

GO_REF:0000002 GO_REF:0000043

NCBI chr10:2,789,227...2,799,783
Ensembl chr10:2,789,277...2,799,531

PROS1

protein S

involved_in

GO_REF:0000043

NCBI chr22:86,728,089...86,840,413
Ensembl chr22:86,728,339...86,840,356

PROZ

protein Z, vitamin K dependent plasma glycoprotein

involved_in
acts_upstream_of_or_within

UniProt
TreeGrafter
MGI
InterPro
Ensembl

(PMID:10829076)

PMID:10829076

GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118

NCBI chr 3:91,156,880...91,171,333
Ensembl chr 3:91,157,307...91,171,042

PTPRJ

protein tyrosine phosphatase receptor type J

involved_in

GO_REF:0000107

NCBI chr 1:17,137,896...17,328,836
Ensembl chr 1:17,135,907...17,328,590

RAB27A

RAB27A, member RAS oncogene family

involved_in
acts_upstream_of_or_within

(PMID:10859366)

PMID:10859366

GO_REF:0000107

NCBI chr26:28,140,972...28,227,847
Ensembl chr26:28,197,464...28,227,963

SERPINA10

serpin family A member 10

involved_in

GO_REF:0000002

NCBI chr24:72,059,523...72,069,989
Ensembl chr24:72,058,780...72,069,085

SERPIND1

serpin family D member 1

involved_in

GO_REF:0000002

NCBI chr19:4,709,896...4,724,620
Ensembl chr19:4,715,806...4,726,111

serpin family E member 2

involved_in
acts_upstream_of_or_within

(PMID:19855083)

PMID:19855083

GO_REF:0000107

NCBI chr10:109,921,619...109,988,137
Ensembl chr10:109,921,598...109,987,513

SHH

sonic hedgehog signaling molecule

involved_in
acts_upstream_of_or_within

(PMID:8835524)

PMID:8835524

GO_REF:0000107

NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395

SLC4A1

solute carrier family 4 member 1 (Diego blood group)

acts_upstream_of_or_within
involved_in

(PMID:9716609)

PMID:9716609

GO_REF:0000107

NCBI chr16:62,126,370...62,146,192
Ensembl chr16:62,131,709...62,146,182

TFPI

tissue factor pathway inhibitor

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr10:73,004,762...73,105,772
Ensembl chr10:73,002,522...73,105,858

TFPI2

tissue factor pathway inhibitor 2

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr21:55,134,921...55,139,862
Ensembl chr21:55,135,198...55,140,801

THBD

thrombomodulin

involved_in

GO_REF:0000043

NCBI chr 2:52,041,950...52,045,946
Ensembl chr 2:52,043,746...52,045,626

TSPAN32

tetraspanin 32

acts_upstream_of_or_within
involved_in

(PMID:16720835)

PMID:16720835

GO_REF:0000107

NCBI chr 1:2,110,218...2,125,839
Ensembl chr 1:2,110,467...2,125,616

VKORC1

vitamin K epoxide reductase complex subunit 1

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640

von Willebrand factor

involved_in
acts_upstream_of_or_within

UniProt
Ensembl
TreeGrafter
MGI

(PMID:17380206), (PMID:21037087), (PMID:9689113)

PMID:9689113 PMID:17380206 PMID:21037087

GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118

NCBI chr11:5,994,499...6,176,949
Ensembl chr11:5,994,039...6,162,260

blood coagulation, common pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

angiopoietin 4

involved_in

GO_REF:0000118

NCBI chr 2:55,619,463...55,654,843
Ensembl chr 2:55,620,694...55,654,001

angiopoietin like 1

involved_in

GO_REF:0000118

NCBI chr25:50,468,283...50,489,283
Ensembl chr25:50,468,826...50,490,343

angiopoietin like 6

involved_in

GO_REF:0000118

Ensembl chr 6:9,160,144...9,164,609

fibrinogen alpha chain

involved_in

GO_REF:0000118

NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405

fibrinogen beta chain

involved_in

GO_REF:0000118

NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662

fibrinogen gamma chain

involved_in

GO_REF:0000118

NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111

fibrinogen like 1

involved_in

GO_REF:0000118

NCBI chr 8:15,962,625...16,016,118
Ensembl chr 8:15,962,053...15,982,336

blood coagulation, fibrin clot formation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F13A1

coagulation factor XIII A chain

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr17:65,885,498...66,040,026
Ensembl chr17:65,885,658...66,040,040

F13B

coagulation factor XIII B chain

involved_in

GO_REF:0000107

NCBI chr25:32,357,540...32,390,349
Ensembl chr25:32,357,993...32,389,973

FBLN1

fibulin 1

involved_in

GO_REF:0000107

NCBI chr19:27,962,669...28,061,356
Ensembl chr19:27,962,642...28,061,364

fibrinogen alpha chain

involved_in

(PMID:16846481)

PMID:16846481

NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405

fibrinogen beta chain

involved_in

GO_REF:0000107

NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662

fibrinogen gamma chain

involved_in

GO_REF:0000107

NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111

ITGB3

integrin subunit beta 3

involved_in
acts_upstream_of_or_within

(PMID:28576878)

GO_REF:0000107

NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857

PDIA4

protein disulfide isomerase family A member 4

acts_upstream_of_or_within

(PMID:28576878)

NCBI chr21:117,574,932...117,601,896
Ensembl chr21:117,574,427...117,601,960

blood coagulation, intrinsic pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apolipoprotein H

involved_in

(PMID:4052628)

PMID:4052628

NCBI chr16:55,209,142...55,231,176

apolipoprotein H

involved_in

GO_REF:0000107

Ensembl chr16:55,209,156...55,231,076

coagulation factor VIII

NCBI chr X:129,090,140...129,315,343
Ensembl chr X:129,088,611...129,312,909

glycoprotein Ib platelet subunit alpha

involved_in

(PMID:10501658)

PMID:10501658

NCBI chr16:4,412,693...4,415,841

glycoprotein Ib platelet subunit alpha

involved_in

GO_REF:0000107

Ensembl chr16:4,413,307...4,415,475

GP1BB

glycoprotein Ib platelet subunit beta

involved_in

(PMID:10501658)

PMID:10501658

NCBI chr19:6,020,618...6,021,646

glycoprotein V platelet

involved_in

GO_REF:0000107

NCBI chr15:88,491,781...88,495,601
Ensembl chr15:88,492,336...88,494,018

GP9

glycoprotein IX platelet

involved_in

GO_REF:0000107

NCBI chr22:52,000,620...52,013,570
Ensembl chr22:52,000,758...52,001,291

body fluid secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

annexin A2

NCBI chr26:23,100,000...23,147,687
Ensembl chr26:23,099,992...23,145,457

EDN1

endothelin 1

acts_upstream_of_or_within
involved_in

(PMID:15314687)

PMID:15314687

GO_REF:0000107

NCBI chr17:59,854,186...59,861,319
Ensembl chr17:59,853,699...59,861,198

GUCA2B

guanylate cyclase activator 2B

acts_upstream_of_or_within

(PMID:14561709)

PMID:14561709

NCBI chr20:90,767,183...90,770,403
Ensembl chr20:90,767,609...90,770,198

RAB14

RAB14, member RAS oncogene family

NCBI chr12:18,382,118...18,406,353
Ensembl chr12:18,390,806...18,403,185

TSC22D3

TSC22 domain family member 3

NCBI chr X:95,535,798...95,606,309
Ensembl chr X:95,535,783...95,539,669

cerebrospinal fluid secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1 (Colton blood group)

involved_in

GO_REF:0000107

NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728

AQP4

aquaporin 4

involved_in

(PMID:30293570)

CACAO

PMID:30293570

NCBI chr18:53,729,143...53,742,916
Ensembl chr18:53,729,186...53,743,156

CELSR2

cadherin EGF LAG seven-pass G-type receptor 2

acts_upstream_of_or_within
involved_in

(PMID:20473291)

PMID:20473291

GO_REF:0000107

NCBI chr20:24,270,963...24,296,263
Ensembl chr20:24,270,952...24,296,647

SLC4A5

solute carrier family 4 member 5

acts_upstream_of_or_within

(PMID:21705333)

PMID:21705333

NCBI chr14:32,923,507...33,060,085

TP73

tumor protein p73

acts_upstream_of_or_within

(PMID:10716451)

PMID:10716451

NCBI chr20:127,958,002...128,035,792
Ensembl chr20:127,958,809...128,013,691

fibrinolysis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

angiopoietin 4

involved_in

GO_REF:0000118

NCBI chr 2:55,619,463...55,654,843
Ensembl chr 2:55,620,694...55,654,001

angiopoietin like 1

involved_in

GO_REF:0000118

NCBI chr25:50,468,283...50,489,283
Ensembl chr25:50,468,826...50,490,343

angiopoietin like 6

involved_in

GO_REF:0000118

Ensembl chr 6:9,160,144...9,164,609

ANXA2

annexin A2

acts_upstream_of_or_within

(PMID:14702107)

PMID:14702107

NCBI chr26:23,100,000...23,147,687
Ensembl chr26:23,099,992...23,145,457

CPB2

carboxypeptidase B2

involved_in

RGD
TreeGrafter
InterPro

PMID:11848438

GO_REF:0000002 GO_REF:0000118 RGD:632532

NCBI chr 3:24,108,854...24,161,669
Ensembl chr 3:24,109,416...24,161,408

coagulation factor XII

involved_in

GO_REF:0000043

NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298

fibrinogen alpha chain

involved_in

GO_REF:0000118

NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405

fibrinogen beta chain

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662

fibrinogen gamma chain

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111

fibrinogen like 1

involved_in

GO_REF:0000118

NCBI chr 8:15,962,625...16,016,118
Ensembl chr 8:15,962,053...15,982,336

glycoprotein Ib platelet subunit alpha

involved_in

(PMID:12855810)

PMID:12855810

NCBI chr16:4,412,693...4,415,841

glycoprotein Ib platelet subunit alpha

involved_in

GO_REF:0000107

Ensembl chr16:4,413,307...4,415,475

histidine rich glycoprotein

involved_in
acts_upstream_of

(PMID:15869579)

UniProt
MGI

PMID:15869579

GO_REF:0000043

NCBI chr15:2,753,819...2,766,946
Ensembl chr15:2,753,810...2,766,478

prothrombin

involved_in

GO_REF:0000107

NCBI chr 1:18,589,658...18,627,459
Ensembl chr 1:18,620,215...18,627,511
Ensembl chr 1:18,620,215...18,627,511

PLAU

plasminogen activator, urokinase

acts_upstream_of_or_within
involved_in

(PMID:9733098)

PMID:9733098

GO_REF:0000107 GO_REF:0000118

NCBI chr 9:57,452,904...57,459,345
Ensembl chr 9:57,452,761...57,459,286

plasminogen

involved_in

GO_REF:0000043 GO_REF:0000104

NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644

PROS1

protein S

involved_in

GO_REF:0000043

NCBI chr22:86,728,089...86,840,413
Ensembl chr22:86,728,339...86,840,356

hemostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANXA7

annexin A7

acts_upstream_of_or_within

(PMID:12925238)

PMID:12925238

NCBI chr 9:57,863,482...57,900,972
Ensembl chr 9:57,863,546...57,900,324

glycoprotein Ib platelet subunit alpha

acts_upstream_of_or_within

(PMID:10706630)

PMID:10706630

NCBI chr16:4,412,693...4,415,841

glycoprotein Ib platelet subunit alpha

involved_in

GO_REF:0000107

Ensembl chr16:4,413,307...4,415,475

TSPAN18

tetraspanin 18

involved_in
acts_upstream_of_or_within

(PMID:30573509)

PMID:30573509

GO_REF:0000107

NCBI chr 1:20,418,064...20,628,756
Ensembl chr 1:20,419,131...20,442,651

TSPAN32

tetraspanin 32

acts_upstream_of_or_within
involved_in

(PMID:16720835)

PMID:16720835

GO_REF:0000107

NCBI chr 1:2,110,218...2,125,839
Ensembl chr 1:2,110,467...2,125,616

von Willebrand factor

acts_upstream_of_or_within
involved_in

(PMID:9689113)

PMID:9689113

GO_REF:0000107

NCBI chr11:5,994,499...6,176,949
Ensembl chr11:5,994,039...6,162,260

ZNF385A

zinc finger protein 385A

involved_in
acts_upstream_of_or_within

(PMID:11927637)

PMID:11927637

GO_REF:0000107

NCBI chr11:50,483,974...50,507,178
Ensembl chr11:50,483,666...50,507,233

lactation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCB1

ATP binding cassette subfamily B member 1

NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274

ALAS2

5'-aminolevulinate synthase 2

NCBI chr X:51,086,062...51,108,564
Ensembl chr X:51,086,066...51,103,505

APRT

adenine phosphoribosyltransferase

NCBI chr 5:74,196,858...74,199,789
Ensembl chr 5:74,194,013...74,199,891

ATP2B2

ATPase plasma membrane Ca2+ transporting 2

acts_upstream_of_or_within

(PMID:15302868)

PMID:15302868

NCBI chr22:46,360,306...46,742,446
Ensembl chr22:46,368,243...46,662,220

ATP7A

ATPase copper transporting alpha

NCBI chr X:66,843,519...66,985,655
Ensembl chr X:66,843,558...66,985,709

ATP7B

ATPase copper transporting beta

acts_upstream_of_or_within

PMID:1588441 PMID:6863890 PMID:16741141 PMID:28089327

(PMID:1588441), (PMID:6863890)

RGD
MGI

MGI:71982 RGD:1599391 RGD:25671605

NCBI chr 3:29,817,712...29,899,302
Ensembl chr 3:29,816,860...29,899,077

BCAT2

branched chain amino acid transaminase 2

PMID:11171603 PMID:11787736

RGD

RGD:1599445 RGD:62398

NCBI chr 6:42,031,003...42,051,770
Ensembl chr 6:42,030,984...42,049,050

CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

NCBI chr14:80,371,154...80,399,193
Ensembl chr14:80,371,096...80,398,914

CAV1

caveolin 1

involved_in
acts_upstream_of_negative_effect

(PMID:12388746)

PMID:12388746

GO_REF:0000107

NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627

CCND1

cyclin D1

involved_in
acts_upstream_of_or_within

(PMID:11747812)
(PMID:10419681)

PMID:10419681 PMID:11747812

GO_REF:0000107

NCBI chr 1:4,909,616...4,922,272
Ensembl chr 1:4,907,353...4,922,357

CDO1

cysteine dioxygenase type 1

NCBI chr23:19,049,612...19,061,783
Ensembl chr23:19,049,262...19,061,740

CHUK

component of inhibitor of nuclear factor kappa B kinase complex

acts_upstream_of_or_within

(PMID:11747812)

PMID:11747812

NCBI chr 9:93,219,374...93,263,077
Ensembl chr 9:93,219,383...93,262,700

CREB1

cAMP responsive element binding protein 1

acts_upstream_of_or_within
involved_in

(PMID:16141355)

PMID:16141355

GO_REF:0000107

NCBI chr10:93,316,774...93,395,187
Ensembl chr10:93,316,840...93,388,832

CSN2

casein beta

involved_in

GO_REF:0000107

NCBI chr 7:18,439,757...18,448,210
Ensembl chr 7:18,441,387...18,445,142

CSN3

casein kappa

acts_upstream_of_or_within
involved_in

(PMID:16698927)

PMID:16698927

GO_REF:0000107 GO_REF:0000118

NCBI chr 7:18,728,058...18,740,953
Ensembl chr 7:18,730,495...18,737,644

CYP27B1

cytochrome P450 family 27 subfamily B member 1

NCBI chr11:53,675,704...53,681,372
Ensembl chr11:53,675,226...53,680,443

DHODH

dihydroorotate dehydrogenase (quinone)

NCBI chr 5:55,161,788...55,177,383
Ensembl chr 5:55,161,916...55,180,896

EIF2AK3

eukaryotic translation initiation factor 2 alpha kinase 3

acts_upstream_of_or_within

(PMID:18852460)

PMID:18852460

NCBI chr14:18,135,973...18,209,471
Ensembl chr14:18,136,291...18,209,457

ERBB4

erb-b2 receptor tyrosine kinase 4

involved_in

(PMID:15534001)
(PMID:10508857)

PMID:10508857 PMID:15534001

NCBI chr10:97,099,090...98,281,697

FOXB1

forkhead box B1

involved_in

GO_REF:0000107

NCBI chr26:23,502,048...23,505,390
Ensembl chr26:23,503,545...23,504,522

GC vitamin D binding protein

NCBI chr 7:20,254,604...20,298,384
Ensembl chr 7:20,253,879...20,298,265

GHRHR

growth hormone releasing hormone receptor

acts_upstream_of_or_within
involved_in

(PMID:1270792), (PMID:2980124)

PMID:1270792 PMID:2980124

GO_REF:0000107

NCBI chr21:27,402,765...27,417,536
Ensembl chr21:27,404,886...27,417,521

GOT2

glutamic-oxaloacetic transaminase 2

NCBI chr 5:44,645,721...44,670,917
Ensembl chr 5:44,645,602...44,670,918

GPAT4

glycerol-3-phosphate acyltransferase 4

involved_in
acts_upstream_of_or_within

(PMID:16449762)

PMID:16449762

GO_REF:0000107

NCBI chr 8:39,557,262...39,598,544
Ensembl chr 8:39,557,275...39,601,567

HIF1A

hypoxia inducible factor 1 subunit alpha

involved_in
acts_upstream_of_or_within

(PMID:12620994)

PMID:12620994

GO_REF:0000107

NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288

hexokinase 2

NCBI chr14:32,385,237...32,443,864
Ensembl chr14:32,385,249...32,442,403

KALRN

kalirin RhoGEF kinase

involved_in
acts_upstream_of_or_within

(PMID:23116210)

PMID:23116210

GO_REF:0000107

NCBI chr22:56,106,677...56,820,004
Ensembl chr22:56,151,819...56,754,538

mucin-4

NCBI chr15:91,313,060...91,345,172

LOC103242912

nucleoside diphosphate kinase A

involved_in
acts_upstream_of_or_within

(PMID:12848338)

PMID:12848338

GO_REF:0000107

NCBI chr16:42,186,039...42,195,608
Ensembl chr16:42,185,260...42,195,616

LOC103243413

signal transducer and activator of transcription 5B

involved_in
acts_upstream_of_or_within

PMID:9630227 PMID:11706048

(PMID:11706048), (PMID:9630227)

UniProt
Ensembl
MGI

GO_REF:0000043 GO_REF:0000107

NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445

MED1

mediator complex subunit 1

involved_in
acts_upstream_of_or_within

(PMID:15647257)

PMID:15647257

GO_REF:0000107

NCBI chr16:66,719,393...66,764,902
Ensembl chr16:66,719,423...66,762,896

MET

MET proto-oncogene, receptor tyrosine kinase

NCBI chr21:85,370,574...85,486,405
Ensembl chr21:85,397,645...85,488,093

metaxin 1

NCBI chr20:8,617,321...8,621,899

NCOA1

nuclear receptor coactivator 1

NCBI chr14:82,898,368...83,028,137
Ensembl chr14:82,897,348...83,013,589

NCOR1

nuclear receptor corepressor 1

NCBI chr16:15,442,315...15,629,411
Ensembl chr16:15,462,640...15,628,512

NCOR2

nuclear receptor corepressor 2

NCBI chr11:119,675,363...119,917,059
Ensembl chr11:119,676,345...119,917,000

NEURL1

neuralized E3 ubiquitin protein ligase 1

acts_upstream_of_or_within
involved_in

(PMID:11585928)

PMID:11585928

GO_REF:0000107

NCBI chr 9:96,542,046...96,641,912
Ensembl chr 9:96,542,473...96,639,761

PAM

peptidylglycine alpha-amidating monooxygenase

NCBI chr23:6,316,428...6,482,959
Ensembl chr23:6,316,428...6,486,751

PMCH

pro-melanin concentrating hormone

NCBI chr11:97,436,682...97,438,345

PPAT

phosphoribosyl pyrophosphate amidotransferase

NCBI chr 7:12,201,434...12,242,418
Ensembl chr 7:12,191,784...12,243,488

PRL

prolactin

involved_in

GO_REF:0000043

NCBI chr17:49,922,750...49,938,084
Ensembl chr17:49,928,321...49,938,631

PRLR

prolactin receptor

involved_in
acts_upstream_of_or_within

(PMID:11445538)
(PMID:11706048), (PMID:16469767)

PMID:11445538 PMID:11706048 PMID:16469767

GO_REF:0000107

NCBI chr 4:33,933,601...34,108,653
Ensembl chr 4:33,949,935...34,108,619

RPLP0

ribosomal protein lateral stalk subunit P0

NCBI chr11:115,547,430...115,552,242
Ensembl chr11:115,547,427...115,550,209

SERPINC1

serpin family C member 1

NCBI chr25:55,271,823...55,289,855

SLC29A1

solute carrier family 29 member 1 (Augustine blood group)

NCBI chr17:27,934,537...27,949,120
Ensembl chr17:27,931,945...27,949,006

SLC29A2

solute carrier family 29 member 2

NCBI chr 1:7,904,813...7,914,344
Ensembl chr 1:7,905,297...7,917,309

SLC30A4

solute carrier family 30 member 4

NCBI chr26:37,692,164...37,732,102
Ensembl chr26:37,692,219...37,731,292

SLC6A3

solute carrier family 6 member 3

acts_upstream_of_or_within
involved_in

(PMID:9247269)

PMID:9247269

GO_REF:0000107

NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866

SOCS2

suppressor of cytokine signaling 2

involved_in
acts_upstream_of_or_within

(PMID:11445538)

PMID:11445538

GO_REF:0000107

NCBI chr11:88,964,805...88,971,147
Ensembl chr11:88,966,940...88,971,515

STAT5A

signal transducer and activator of transcription 5A

acts_upstream_of_or_within
involved_in

PMID:7519723 PMID:8584036 PMID:9630227 PMID:11706048

(PMID:9630227)
(PMID:11706048)

RGD
MGI
UniProt

GO_REF:0000043 RGD:151665740 RGD:730121

NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026

UMPS

uridine monophosphate synthetase

NCBI chr22:56,081,897...56,097,164
Ensembl chr22:56,082,103...56,097,105

UPRT

uracil phosphoribosyltransferase homolog

NCBI chr X:64,815,163...64,846,198
Ensembl chr X:64,815,183...64,849,547

USF2

upstream transcription factor 2, c-fos interacting

acts_upstream_of_or_within
involved_in

(PMID:12907752)

PMID:12907752

GO_REF:0000107

NCBI chr 6:30,202,224...30,212,783
Ensembl chr 6:30,202,375...30,213,058

VDR

vitamin D receptor

involved_in
acts_upstream_of_or_within

(PMID:15178742)

PMID:15178742

GO_REF:0000107

NCBI chr11:44,062,198...44,126,295
Ensembl chr11:44,065,457...44,166,684

VEGFA

vascular endothelial growth factor A

acts_upstream_of_or_within

(PMID:17625068)

PMID:17625068

NCBI chr17:28,377,959...28,394,508

VEGFA

vascular endothelial growth factor A

involved_in

GO_REF:0000107

Ensembl chr17:28,379,880...28,393,995

XDH

xanthine dehydrogenase

involved_in
acts_upstream_of_or_within

(PMID:12502743)

PMID:12502743

GO_REF:0000107

NCBI chr14:76,084,693...76,162,840
Ensembl chr14:76,085,368...76,163,936

ZBTB7B

zinc finger and BTB domain containing 7B

involved_in

GO_REF:0000107

NCBI chr20:8,812,514...8,829,128
Ensembl chr20:8,812,351...8,817,286

milk ejection reflex

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GJA1

gap junction protein alpha 1

involved_in
acts_upstream_of_or_within

(PMID:20089884)

PMID:20089884

GO_REF:0000107

NCBI chr13:52,397,291...52,410,341
Ensembl chr13:52,396,109...52,410,339

mucus secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADA

adenosine deaminase

acts_upstream_of

(PMID:15630442)
(PMID:15240734), (PMID:15630442)

PMID:15240734 PMID:15630442

NCBI chr 2:19,167,209...19,200,233

ADORA1

adenosine A1 receptor

acts_upstream_of
involved_in

(PMID:15630442)

PMID:15630442

GO_REF:0000107

NCBI chr25:26,180,898...26,221,424
Ensembl chr25:26,182,446...26,220,776

AGR2

anterior gradient 2, protein disulphide isomerase family member

involved_in
acts_upstream_of_or_within

(PMID:19359471)

PMID:19359471

GO_REF:0000107

NCBI chr21:41,311,250...41,324,806
Ensembl chr21:41,312,415...41,326,663

ANO1

anoctamin 1

involved_in

GO_REF:0000107

NCBI chr 1:4,373,256...4,581,914
Ensembl chr 1:4,373,252...4,490,557

ATG5

autophagy related 5

acts_upstream_of
involved_in

(PMID:24185898)

GO_REF:0000107

NCBI chr13:67,482,538...67,619,201
Ensembl chr13:67,482,595...67,617,902

ATG7

autophagy related 7

acts_upstream_of

(PMID:24185898)

NCBI chr22:47,187,305...47,571,309
Ensembl chr22:47,325,614...47,571,070

ENPP1

ectonucleotide pyrophosphatase/phosphodiesterase 1

involved_in

(PMID:27959908)

PMID:27959908

NCBI chr13:41,670,416...41,755,549

FOSL2

FOS like 2, AP-1 transcription factor subunit

involved_in
acts_upstream_of_or_within

(PMID:30233597)

PMID:30233597

GO_REF:0000107

NCBI chr14:79,201,128...79,222,363
Ensembl chr14:79,201,649...79,222,373

HTR4

5-hydroxytryptamine receptor 4

involved_in

GO_REF:0000107

NCBI chr23:51,087,430...51,279,915
Ensembl chr23:51,087,285...51,182,200

LOC103224223

adenosine receptor A3

acts_upstream_of

(PMID:15240734)

PMID:15240734

NCBI chr20:22,043,367...22,127,103
Ensembl chr20:22,106,190...22,123,629

LOC103233451

cytochrome b-245 light chain

involved_in
acts_upstream_of

(PMID:24185898)

GO_REF:0000107

NCBI chr 5:74,023,134...74,030,793
Ensembl chr 5:74,023,082...74,030,750

MAP1LC3B

microtubule associated protein 1 light chain 3 beta

acts_upstream_of

(PMID:24185898)

NCBI chr 5:72,762,428...72,774,204
Ensembl chr 5:72,763,050...72,772,770

MUC2

mucin 2, oligomeric mucus/gel-forming

involved_in

(PMID:17058067)
(PMID:35337837)

PMID:17058067 PMID:35337837

NCBI chr 1:893,554...926,854

P2RY2

purinergic receptor P2Y2

acts_upstream_of

(PMID:17728398)

NCBI chr 1:64,461,929...64,481,429
Ensembl chr 1:64,479,642...64,480,775

PRKCE

protein kinase C epsilon

involved_in
acts_upstream_of

(PMID:17728398)

GO_REF:0000107

NCBI chr14:61,022,903...61,570,390
Ensembl chr14:61,026,017...61,242,343

SCNN1B

sodium channel epithelial 1 subunit beta

involved_in
acts_upstream_of_or_within

(PMID:22419116)

PMID:22419116

GO_REF:0000107

NCBI chr 5:21,021,181...21,107,746
Ensembl chr 5:21,022,133...21,107,824

TRAF3IP2

TRAF3 interacting protein 2

involved_in

GO_REF:0000107

NCBI chr13:62,272,893...62,320,096
Ensembl chr13:62,285,589...62,324,312

VAMP2

vesicle associated membrane protein 2

NOT|involved_in

(PMID:22144578)

PMID:22144578

NCBI chr16:7,539,098...7,542,466

VAMP3

vesicle associated membrane protein 3

NOT|involved_in

(PMID:22144578)

PMID:22144578

NCBI chr20:123,973,672...123,984,230
Ensembl chr20:123,971,992...123,984,187

VAMP8

vesicle associated membrane protein 8

involved_in

GO_REF:0000107

NCBI chr14:21,575,057...21,580,054
Ensembl chr14:21,575,161...21,579,820

multicellular organismal-level water homeostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1 (Colton blood group)

involved_in
acts_upstream_of_or_within

(PMID:12034763)

PMID:12034763

GO_REF:0000107

NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728

AQP4

aquaporin 4

acts_upstream_of_or_within
involved_in

(PMID:12034763)

PMID:12034763

GO_REF:0000107

NCBI chr18:53,729,143...53,742,916
Ensembl chr18:53,729,186...53,743,156

arginine vasopressin

NCBI chr 2:33,761,066...33,764,608
Ensembl chr 2:33,761,140...33,763,172

BPIFA1

BPI fold containing family A member 1

involved_in

GO_REF:0000107

NCBI chr 2:37,571,577...37,579,529
Ensembl chr 2:37,573,837...37,578,667

CFTR

CF transmembrane conductance regulator

involved_in

(PMID:19621064)

PMID:19621064

NCBI chr21:86,154,313...86,332,436

EXT1

exostosin glycosyltransferase 1

acts_upstream_of_or_within

(PMID:31365577)

PMID:31365577

NCBI chr 8:112,435,733...112,751,301

EXT1

exostosin glycosyltransferase 1

involved_in

GO_REF:0000107

Ensembl chr 8:112,436,088...112,474,443

EXT2

exostosin glycosyltransferase 2

involved_in
acts_upstream_of_or_within

(PMID:31365577)

PMID:31365577

GO_REF:0000107

NCBI chr 1:21,077,159...21,282,317
Ensembl chr 1:21,119,987...21,281,635

SCNN1A

sodium channel epithelial 1 subunit alpha

involved_in

GO_REF:0000107

NCBI chr11:6,384,073...6,418,620
Ensembl chr11:6,383,956...6,416,337

SCNN1B

sodium channel epithelial 1 subunit beta

involved_in
acts_upstream_of_or_within

(PMID:17430990), (PMID:28567665)

PMID:17430990 PMID:28567665

GO_REF:0000107

NCBI chr 5:21,021,181...21,107,746
Ensembl chr 5:21,022,133...21,107,824

SCNN1G

sodium channel epithelial 1 subunit gamma

involved_in

GO_REF:0000107

NCBI chr 5:20,860,062...20,924,628
Ensembl chr 5:20,891,416...20,924,819

TRPV4

transient receptor potential cation channel subfamily V member 4

involved_in

GO_REF:0000107

NCBI chr11:105,020,972...105,072,660

UMOD

uromodulin

acts_upstream_of_or_within
involved_in

(PMID:29357410)

PMID:29357410

GO_REF:0000107

NCBI chr 5:18,620,927...18,641,312
Ensembl chr 5:18,619,895...18,638,719

negative regulation of blood coagulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADTRP

androgen dependent TFPI regulating protein

involved_in

GO_REF:0000107

NCBI chr17:60,371,412...60,436,988
Ensembl chr17:60,368,546...60,438,864

annexin A5

NCBI chr 7:68,940,365...68,970,324
Ensembl chr 7:68,940,304...68,970,811

APOE

apolipoprotein E

involved_in

GO_REF:0000107

NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438

apolipoprotein H

involved_in

(PMID:4052628)

PMID:4052628

NCBI chr16:55,209,142...55,231,176

apolipoprotein H

involved_in

GO_REF:0000107

Ensembl chr16:55,209,156...55,231,076

KNG1

kininogen 1

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr15:81,002,287...81,027,893

prothrombin

involved_in

GO_REF:0000107

NCBI chr 1:18,589,658...18,627,459
Ensembl chr 1:18,620,215...18,627,511
Ensembl chr 1:18,620,215...18,627,511

PROC

protein C, inactivator of coagulation factors Va and VIIIa

involved_in
acts_upstream_of_or_within

PMID:1440533 PMID:9616155 PMID:9788960

(PMID:9788960)
(PMID:9616155)

RGD
TreeGrafter
MGI

GO_REF:0000118 RGD:11100042

NCBI chr10:2,789,227...2,799,783
Ensembl chr10:2,789,277...2,799,531

serpin family E member 2

involved_in

GO_REF:0000107

NCBI chr10:109,921,619...109,988,137
Ensembl chr10:109,921,598...109,987,513

TFPI

tissue factor pathway inhibitor

involved_in

GO_REF:0000107

NCBI chr10:73,004,762...73,105,772
Ensembl chr10:73,002,522...73,105,858

THBD

thrombomodulin

involved_in

GO_REF:0000107

NCBI chr 2:52,041,950...52,045,946
Ensembl chr 2:52,043,746...52,045,626

tetraspanin 8

NCBI chr11:66,726,714...66,882,234
Ensembl chr11:66,725,231...66,758,091

negative regulation of fibrinolysis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apolipoprotein H

involved_in

(PMID:14726399)

PMID:14726399

NCBI chr16:55,209,142...55,231,176

apolipoprotein H

involved_in

GO_REF:0000107

Ensembl chr16:55,209,156...55,231,076

carboxypeptidase B2

NCBI chr 3:24,108,854...24,161,669
Ensembl chr 3:24,109,416...24,161,408

histidine rich glycoprotein

acts_upstream_of_or_within
involved_in

(PMID:15869579)

MGI
TreeGrafter

PMID:15869579

GO_REF:0000118

NCBI chr15:2,753,819...2,766,946
Ensembl chr15:2,753,810...2,766,478

plasminogen

involved_in

(PMID:14726399)

PMID:14726399

NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644

SERPINE1

serpin family E member 1

involved_in

GO_REF:0000107

NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202

SERPINF2

serpin family F member 2

involved_in

RGD
Ensembl
InterPro

PMID:6506034

GO_REF:0000002 GO_REF:0000107 RGD:1625541

NCBI chr16:1,392,562...1,404,574
Ensembl chr16:1,392,571...1,404,636

THBS1

thrombospondin 1

involved_in

GO_REF:0000107

NCBI chr26:43,410,693...43,427,816
Ensembl chr26:43,410,580...43,427,812

negative regulation of glomerular filtration

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

coagulation factor II thrombin receptor

involved_in

PMID:12644441

NCBI chr 4:70,992,406...71,010,512
Ensembl chr 4:70,992,477...71,009,456

GJA5

gap junction protein alpha 5

protein tyrosine phosphatase receptor type O

involved_in

PMID:19403647

NCBI chr11:15,225,375...15,494,559
Ensembl chr11:15,392,926...15,495,807

TTR

transthyretin

involved_in

(PMID:11036082)

PMID:11036082

NCBI chr18:49,124,302...49,131,495
Ensembl chr18:49,124,121...49,131,399

urotensin 2

NCBI chr20:123,903,137...123,910,180

urotensin 2 receptor

NCBI chr16:74,284,472...74,291,074
Ensembl chr16:74,288,333...74,289,502

negative regulation of glomerular filtration by angiotensin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LOC103233451

cytochrome b-245 light chain

NCBI chr 5:74,023,134...74,030,793
Ensembl chr 5:74,023,082...74,030,750

negative regulation of hemostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

COMP

cartilage oligomeric matrix protein

involved_in
acts_upstream_of_or_within

(PMID:26045608)

PMID:26045608

GO_REF:0000107

NCBI chr 6:17,246,617...17,255,561
Ensembl chr 6:17,246,762...17,255,126

negative regulation of mucus secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADA

adenosine deaminase

acts_upstream_of_or_within

(PMID:15240734), (PMID:15630442)
(PMID:15630442)

PMID:15240734 PMID:15630442

NCBI chr 2:19,167,209...19,200,233

ADORA1

adenosine A1 receptor

acts_upstream_of_or_within
involved_in

(PMID:15630442)

PMID:15630442

GO_REF:0000107

NCBI chr25:26,180,898...26,221,424
Ensembl chr25:26,182,446...26,220,776

negative regulation of pancreatic amylase secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MADD

MAP kinase activating death domain

NCBI chr 1:17,987,573...18,041,317
Ensembl chr 1:17,986,860...18,042,266

negative regulation of pancreatic juice secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NR1H3

nuclear receptor subfamily 1 group H member 3

involved_in

GO_REF:0000107

NCBI chr 1:18,041,495...18,061,196
Ensembl chr 1:18,041,830...18,051,501

STK39

serine/threonine kinase 39

involved_in

GO_REF:0000107

NCBI chr10:53,451,035...53,747,847
Ensembl chr10:53,450,891...53,682,993

WNK1

WNK lysine deficient protein kinase 1

involved_in
acts_upstream_of_or_within

(PMID:21317537)

PMID:21317537

GO_REF:0000107

NCBI chr11:736,668...893,404
Ensembl chr11:737,590...890,762

WNK3

WNK lysine deficient protein kinase 3

involved_in

GO_REF:0000107

NCBI chr X:50,320,585...50,452,911
Ensembl chr X:50,320,674...50,452,943

WNK4

WNK lysine deficient protein kinase 4

acts_upstream_of_or_within

(PMID:21317537)

PMID:21317537

NCBI chr16:63,494,090...63,512,068

negative regulation of platelet activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

APOE

apolipoprotein E

involved_in

GO_REF:0000107

NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438

C1QTNF1

C1q and TNF related 1

involved_in

GO_REF:0000107

NCBI chr16:70,993,035...71,018,240
Ensembl chr16:70,992,936...71,018,327

glycoprotein V platelet

acts_upstream_of_or_within

(PMID:10557321), (PMID:11435305)

PMID:10557321 PMID:11435305

NCBI chr15:88,491,781...88,495,601
Ensembl chr15:88,492,336...88,494,018

PDGFA

platelet derived growth factor subunit A

involved_in

GO_REF:0000107

NCBI chr28:21,044,549...21,068,411
Ensembl chr28:21,047,219...21,069,827

PDGFB

platelet derived growth factor subunit B

involved_in

GO_REF:0000107

NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395

PDGFRA

platelet derived growth factor receptor alpha

involved_in

GO_REF:0000107

NCBI chr 7:14,243,291...14,307,373
Ensembl chr 7:14,241,070...14,307,422

serpin family E member 2

involved_in
acts_upstream_of_or_within

(PMID:19855083)

PMID:19855083

GO_REF:0000107

NCBI chr10:109,921,619...109,988,137
Ensembl chr10:109,921,598...109,987,513

negative regulation of platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADAMTS18

ADAM metallopeptidase with thrombospondin type 1 motif 18

involved_in
acts_upstream_of_or_within

(PMID:19218546)

PMID:19218546

GO_REF:0000107

NCBI chr 5:62,764,081...62,921,394
Ensembl chr 5:62,765,939...62,918,697

ALOX12

arachidonate 12-lipoxygenase, 12S type

involved_in

GO_REF:0000107

NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738

C1QTNF1

C1q and TNF related 1

involved_in

GO_REF:0000107

NCBI chr16:70,993,035...71,018,240
Ensembl chr16:70,992,936...71,018,327

CD9

CD9 molecule

involved_in

GO_REF:0000107

NCBI chr11:6,236,449...6,275,904
Ensembl chr11:6,236,494...6,275,909

CEACAM1

CEA cell adhesion molecule 1

involved_in

(PMID:19008452)

PMID:19008452

NCBI chr 6:36,708,368...36,731,729
Ensembl chr 6:36,708,311...36,730,189

PRKCD

protein kinase C delta

involved_in

GO_REF:0000107

NCBI chr22:14,561,401...14,592,877
Ensembl chr22:14,565,282...14,592,873

PRKG1

protein kinase cGMP-dependent 1

involved_in

(PMID:16990611)

PMID:16990611

NCBI chr 9:78,858,269...80,188,163

PRKG1

protein kinase cGMP-dependent 1

involved_in

GO_REF:0000107

Ensembl chr 9:78,858,137...79,352,802

serpin family E member 2

involved_in

GO_REF:0000107

NCBI chr10:109,921,619...109,988,137
Ensembl chr10:109,921,598...109,987,513

SH2B3

SH2B adaptor protein 3

involved_in

GO_REF:0000107

NCBI chr11:106,657,601...106,703,940
Ensembl chr11:106,670,685...106,700,619

TMX1

thioredoxin related transmembrane protein 1

involved_in

GO_REF:0000107

NCBI chr24:28,334,017...28,350,571
Ensembl chr24:28,333,357...28,352,457

UBASH3B

ubiquitin associated and SH3 domain containing B

acts_upstream_of_or_within
involved_in

(PMID:20585042)

PMID:20585042

GO_REF:0000107

NCBI chr 1:114,053,792...114,218,909
Ensembl chr 1:114,054,384...114,218,912

negative regulation of saliva secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DCANP1

dendritic cell associated nuclear protein 1

involved_in

(PMID:23419067)

CAFA

PMID:23419067

NCBI chr23:38,224,287...38,227,481

NEUROG1

neurogenin 1

involved_in

GO_REF:0000107

NCBI chr23:38,318,432...38,320,099
Ensembl chr23:38,319,121...38,319,834

TIFAB

TIFA inhibitor

involved_in

(PMID:23419067)

CAFA

PMID:23419067

NCBI chr23:38,228,904...38,232,892

TIFAB

TIFA inhibitor

involved_in

GO_REF:0000107

Ensembl chr23:38,229,485...38,232,210

negative regulation of urine volume

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCY6

adenylate cyclase 6

involved_in

(PMID:20466003)

PMID:20466003

NCBI chr11:45,006,220...45,031,481
Ensembl chr11:45,005,637...45,025,501

adrenoceptor beta 1

NCBI chr 9:106,920,520...106,923,424
Ensembl chr 9:106,920,610...106,922,058

adrenoceptor beta 2

NCBI chr23:51,445,920...51,447,942
Ensembl chr23:51,446,154...51,447,401

AVPR2

arginine vasopressin receptor 2

NCBI chr X:128,328,728...128,331,482
Ensembl chr X:128,329,449...128,331,019

MLLT6

MLLT6, PHD finger containing

involved_in
acts_upstream_of_or_within

(PMID:21546577)

PMID:21546577

GO_REF:0000107

NCBI chr16:67,466,001...67,490,019
Ensembl chr16:67,465,913...67,490,251

OXT

oxytocin/neurophysin I prepropeptide

NCBI chr 2:33,749,520...33,750,981
Ensembl chr 2:33,750,108...33,750,968

SLC4A1

solute carrier family 4 member 1 (Diego blood group)

acts_upstream_of_or_within
involved_in

(PMID:17409310)

PMID:17409310

GO_REF:0000107

NCBI chr16:62,126,370...62,146,192
Ensembl chr16:62,131,709...62,146,182

SLC5A2

solute carrier family 5 member 2

NCBI chr 5:28,183,141...28,191,352
Ensembl chr 5:28,183,618...28,191,120

urotensin 2

NCBI chr20:123,903,137...123,910,180

urotensin 2 receptor

NCBI chr16:74,284,472...74,291,074
Ensembl chr16:74,288,333...74,289,502

pancreatic juice secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1 (Colton blood group)

involved_in

GO_REF:0000107

NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728

AQP5

aquaporin 5

involved_in

GO_REF:0000107

NCBI chr11:46,190,504...46,195,461

CEL

carboxyl ester lipase

involved_in

GO_REF:0000107

NCBI chr12:5,053,817...5,077,487
Ensembl chr12:5,066,882...5,077,227

COPA

COPI coat complex subunit alpha

acts_upstream_of_or_within
involved_in

(PMID:1429581)

PMID:1429581

GO_REF:0000107

NCBI chr20:3,605,903...3,658,555
Ensembl chr20:3,606,293...3,659,402

phosphatidylserine exposure on blood platelet

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ANO6

anoctamin 6

involved_in

GO_REF:0000107

NCBI chr11:41,420,206...41,633,323
Ensembl chr11:41,419,901...41,633,347

platelet activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTN1

actinin alpha 1

NOT|involved_in

(PMID:24069336)

PMID:24069336

NCBI chr24:46,089,989...46,196,897
Ensembl chr24:46,085,751...46,196,886

ADRA2A

adrenoceptor alpha 2A

involved_in

GO_REF:0000002

NCBI chr 9:104,015,577...104,019,364
Ensembl chr 9:104,016,580...104,017,932

ADRA2B

adrenoceptor alpha 2B

involved_in

GO_REF:0000002

NCBI chr14:558,876...562,959
Ensembl chr14:561,057...562,400

ADRA2C

adrenoceptor alpha 2C

involved_in

GO_REF:0000002

NCBI chr27:44,950,928...44,953,245
Ensembl chr27:44,951,457...44,952,827

AXL

AXL receptor tyrosine kinase

involved_in
acts_upstream_of_or_within

(PMID:15650770)

Ensembl
TreeGrafter
MGI

PMID:15650770

GO_REF:0000107 GO_REF:0000118

NCBI chr 6:35,537,718...35,580,143
Ensembl chr 6:35,537,773...35,580,716

BLOC1S3

biogenesis of lysosomal organelles complex 1 subunit 3

involved_in

GO_REF:0000107

NCBI chr 6:38,623,639...38,642,217
Ensembl chr 6:38,639,659...38,640,261

C1GALT1C1

C1GALT1 specific chaperone 1

acts_upstream_of_or_within
involved_in

(PMID:22988088)

GO_REF:0000107

CD40 ligand

involved_in

UniProt
Ensembl

GO_REF:0000104 GO_REF:0000107

NCBI chr X:111,655,301...111,667,602
Ensembl chr X:111,655,397...111,666,639

CTSG

cathepsin G

involved_in

GO_REF:0000107

NCBI chr24:1,518,004...1,521,980
Ensembl chr24:1,518,119...1,520,709

DGKA

diacylglycerol kinase alpha

involved_in

GO_REF:0000117

NCBI chr11:51,871,566...51,901,593
Ensembl chr11:51,871,563...51,892,637

DGKB

diacylglycerol kinase beta

involved_in

GO_REF:0000117

NCBI chr21:43,176,715...43,929,833
Ensembl chr21:43,176,989...43,746,258

DGKD

diacylglycerol kinase delta

involved_in

GO_REF:0000117

NCBI chr10:119,390,217...119,509,148
Ensembl chr10:119,390,330...119,511,134

DGKE

diacylglycerol kinase epsilon

involved_in

GO_REF:0000117

NCBI chr16:36,540,155...36,575,506
Ensembl chr16:36,546,670...36,574,820

DGKG

diacylglycerol kinase gamma

involved_in

GO_REF:0000117

NCBI chr15:3,062,445...3,275,933
Ensembl chr15:3,104,120...3,273,344

DGKH

diacylglycerol kinase eta

involved_in

GO_REF:0000117

NCBI chr 3:20,224,255...20,408,493
Ensembl chr 3:20,233,249...20,407,927

DGKI

diacylglycerol kinase iota

involved_in

GO_REF:0000117

NCBI chr21:106,074,522...106,544,009
Ensembl chr21:106,076,928...106,317,825

DGKK

diacylglycerol kinase kappa

involved_in

GO_REF:0000117

NCBI chr X:47,156,308...47,265,027
Ensembl chr X:47,156,317...47,264,824

DGKQ

diacylglycerol kinase theta

involved_in

GO_REF:0000117

NCBI chr27:47,804,904...47,819,291
Ensembl chr27:47,805,017...47,817,583

DGKZ

diacylglycerol kinase zeta

involved_in

GO_REF:0000117

NCBI chr 1:18,949,360...18,997,957
Ensembl chr 1:18,948,425...18,982,354

ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

acts_upstream_of_or_within

(PMID:11929769)

PMID:11929769

NCBI chr 9:88,921,826...89,034,418
Ensembl chr 9:88,922,007...89,032,880

ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

acts_upstream_of_or_within
involved_in

(PMID:11929769)

PMID:11929769

GO_REF:0000107

NCBI chr12:1,137,500...1,142,798
Ensembl chr12:1,137,495...1,143,231

coagulation factor II thrombin receptor

involved_in

GO_REF:0000107

NCBI chr 4:70,992,406...71,010,512
Ensembl chr 4:70,992,477...71,009,456

F2RL3

F2R like thrombin or trypsin receptor 3

involved_in

GO_REF:0000107

NCBI chr 6:15,397,552...15,400,708

fibrinogen alpha chain

involved_in

GO_REF:0000002

NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405

fibrinogen beta chain

involved_in

GO_REF:0000002

NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662

fibrinogen gamma chain

involved_in

GO_REF:0000002

NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111

FZD6

frizzled class receptor 6

acts_upstream_of_or_within
involved_in

(PMID:19901330)

PMID:19901330

GO_REF:0000107

NCBI chr 8:98,154,173...98,187,864
Ensembl chr 8:98,154,196...98,188,069

galactosidase alpha

NCBI chr X:89,738,097...89,749,740
Ensembl chr X:89,737,966...89,750,539

GNA13

G protein subunit alpha 13

acts_upstream_of_or_within
involved_in

(PMID:14528298)

PMID:14528298

GO_REF:0000107

NCBI chr16:56,372,146...56,419,754
Ensembl chr16:56,372,276...56,414,827

glycoprotein V platelet

acts_upstream_of

(PMID:10557321), (PMID:11435305)

PMID:10557321 PMID:11435305

NCBI chr15:88,491,781...88,495,601
Ensembl chr15:88,492,336...88,494,018

histidine rich glycoprotein

involved_in

GO_REF:0000107

NCBI chr15:2,753,819...2,766,946
Ensembl chr15:2,753,810...2,766,478

ITGB3

integrin subunit beta 3

involved_in

GO_REF:0000107

NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857

ITPR3

inositol 1,4,5-trisphosphate receptor type 3

involved_in

GO_REF:0000107

NCBI chr17:38,381,862...38,456,505
Ensembl chr17:38,381,743...38,456,499

prothrombin

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 1:18,589,658...18,627,459
Ensembl chr 1:18,620,215...18,627,511
Ensembl chr 1:18,620,215...18,627,511

LOC119623289

diacylglycerol kinase theta

involved_in

GO_REF:0000117

MERTK

MER proto-oncogene, tyrosine kinase

acts_upstream_of_or_within
involved_in

(PMID:15650770)

PMID:15650770

GO_REF:0000107

NCBI chr14:14,971,858...15,100,736
Ensembl chr14:15,001,471...15,101,025

P2RX1

purinergic receptor P2X 1

acts_upstream_of_or_within
involved_in

(PMID:12913094)

PMID:12913094

GO_REF:0000107

NCBI chr16:3,377,526...3,399,374
Ensembl chr16:3,377,483...3,398,360

P2RY12

purinergic receptor P2Y12

acts_upstream_of_or_within
involved_in

(PMID:11413167)

PMID:11413167

GO_REF:0000107

NCBI chr15:39,315,140...39,361,614
Ensembl chr15:39,359,612...39,360,637

PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

acts_upstream_of_or_within

(PMID:15834429)

PMID:15834429

NCBI chr15:51,705,585...51,885,848
Ensembl chr15:51,775,733...51,889,238

PPIA

peptidylprolyl isomerase A

involved_in

(PMID:24429998)

PMID:24429998

NCBI chr21:13,876,099...13,883,546
Ensembl chr21:13,876,099...13,883,462

RAP2B

RAP2B, member of RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr15:37,502,236...37,505,829
Ensembl chr15:37,504,830...37,505,378

RASA3

RAS p21 protein activator 3

involved_in

GO_REF:0000107

NCBI chr 3:91,848,158...91,974,675
Ensembl chr 3:91,848,160...91,974,555

serpin family E member 2

involved_in
acts_upstream_of

(PMID:19855083)

PMID:19855083

GO_REF:0000107

NCBI chr10:109,921,619...109,988,137
Ensembl chr10:109,921,598...109,987,513

SRF

serum response factor

acts_upstream_of_or_within
involved_in

(PMID:20525922)

PMID:20525922

GO_REF:0000107

NCBI chr17:28,983,161...28,993,465
Ensembl chr17:28,983,002...28,992,995

TREML1

triggering receptor expressed on myeloid cells like 1

involved_in

GO_REF:0000107

NCBI chr17:31,002,893...31,008,366
Ensembl chr17:31,003,331...31,008,036

TYRO3

TYRO3 protein tyrosine kinase

acts_upstream_of_or_within
involved_in

(PMID:15650770)

PMID:15650770

GO_REF:0000107

NCBI chr26:41,429,667...41,449,130
Ensembl chr26:41,429,556...41,449,175

UBASH3B

ubiquitin associated and SH3 domain containing B

acts_upstream_of_or_within
involved_in

(PMID:27609517)

PMID:27609517

GO_REF:0000107

NCBI chr 1:114,053,792...114,218,909
Ensembl chr 1:114,054,384...114,218,912

von Willebrand factor

involved_in
NOT|acts_upstream_of_or_within

PMID:10930441 PMID:17380206 PMID:21037087

(PMID:17380206)
(PMID:10930441), (PMID:21037087)

UniProt
Ensembl
MGI

GO_REF:0000104 GO_REF:0000107

NCBI chr11:5,994,499...6,176,949
Ensembl chr11:5,994,039...6,162,260

WNT3A

Wnt family member 3A

acts_upstream_of_or_within
involved_in

(PMID:19901330)

PMID:19901330

GO_REF:0000107

NCBI chr25:1,664,316...1,675,006
Ensembl chr25:1,666,053...1,719,881

platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACTB

actin beta

involved_in

(PMID:23382103)

NCBI chr28:16,195,676...16,197,161
Ensembl chr12:52,426,752...52,427,879

ACTG1

actin gamma 1

involved_in

(PMID:23382103)

NCBI chr16:73,456,907...73,459,777

ACTN1

actinin alpha 1

NOT|involved_in

(PMID:23434115)

PMID:23434115

NCBI chr24:46,089,989...46,196,897
Ensembl chr24:46,085,751...46,196,886

angiopoietin 4

involved_in

GO_REF:0000118

NCBI chr 2:55,619,463...55,654,843
Ensembl chr 2:55,620,694...55,654,001

angiopoietin like 1

involved_in

GO_REF:0000118

NCBI chr25:50,468,283...50,489,283
Ensembl chr25:50,468,826...50,490,343

angiopoietin like 6

involved_in

GO_REF:0000118

Ensembl chr 6:9,160,144...9,164,609

BLOC1S4

biogenesis of lysosomal organelles complex 1 subunit 4

acts_upstream_of_or_within
involved_in

(PMID:11110696)

PMID:11110696

GO_REF:0000107

NCBI chr27:42,836,231...42,837,514
Ensembl chr27:42,836,366...42,837,016

CFH

complement factor H

acts_upstream_of_or_within

(PMID:28057640)

PMID:28057640

NCBI chr25:32,557,697...32,744,763

CLIC1

chloride intracellular channel 1

involved_in

(PMID:23382103)

NCBI chr17:40,286,051...40,292,377
Ensembl chr17:40,286,491...40,292,113

COMP

cartilage oligomeric matrix protein

involved_in
acts_upstream_of_or_within

(PMID:26045608)

PMID:26045608

GO_REF:0000107

NCBI chr 6:17,246,617...17,255,561
Ensembl chr 6:17,246,762...17,255,126

CSRP1

cysteine and glycine rich protein 1

involved_in

(PMID:23382103)

NCBI chr25:27,908,426...27,932,107
Ensembl chr25:27,908,554...27,933,275

ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

involved_in

GO_REF:0000107

NCBI chr 9:88,921,826...89,034,418
Ensembl chr 9:88,922,007...89,032,880

F2RL3

F2R like thrombin or trypsin receptor 3

acts_upstream_of_or_within

(PMID:28032533)

PMID:28032533

NCBI chr 6:15,397,552...15,400,708

FERMT3

FERM domain containing kindlin 3

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 1:10,012,007...10,031,177
Ensembl chr 1:10,009,626...10,031,209

fibrinogen alpha chain

involved_in

GO_REF:0000118

NCBI chr 7:101,127,554...101,134,881
Ensembl chr 7:101,125,791...101,134,405

fibrinogen beta chain

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 7:101,106,468...101,114,566
Ensembl chr 7:101,106,483...101,114,662

fibrinogen gamma chain

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 7:101,148,457...101,157,245
Ensembl chr 7:101,148,058...101,157,111

fibrinogen like 1

involved_in

GO_REF:0000118

NCBI chr 8:15,962,625...16,016,118
Ensembl chr 8:15,962,053...15,982,336

FIBP

FGF1 intracellular binding protein

involved_in

GO_REF:0000118

NCBI chr 1:8,369,279...8,374,246

FLNA

filamin A

involved_in

(PMID:23382103)

NCBI chr X:128,657,580...128,683,812
Ensembl chr X:128,657,393...128,680,531

GATA1

GATA binding protein 1

involved_in

GO_REF:0000107

NCBI chr X:45,912,638...45,920,415
Ensembl chr X:45,917,231...45,920,268

galactosidase alpha

NCBI chr X:89,738,097...89,749,740
Ensembl chr X:89,737,966...89,750,539

GP6

glycoprotein VI platelet

involved_in
acts_upstream_of_or_within

PMID:17322098 PMID:28032533

(PMID:28032533)

Ensembl
MGI
RGD

GO_REF:0000107 RGD:401824682

NCBI chr 6:47,614,221...47,630,020
Ensembl chr 6:47,614,384...47,624,160

HSPB1

heat shock protein family B (small) member 1

involved_in

(PMID:23382103)

NCBI chr28:10,442,530...10,443,804
Ensembl chr28:10,442,398...10,443,855

ILK

integrin linked kinase

involved_in

(PMID:23382103)

NCBI chr 1:58,214,630...58,221,770
Ensembl chr 1:58,213,310...58,221,217

ITGB3

integrin subunit beta 3

involved_in
acts_upstream_of_or_within

(PMID:28576878)

Ensembl
TreeGrafter
MGI

GO_REF:0000107 GO_REF:0000118

NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857

LOC103218397

tetraspanin-9

acts_upstream_of_or_within

(PMID:28032533)

PMID:28032533

NCBI chr11:3,138,764...3,347,796
Ensembl chr11:3,145,015...3,347,849

LOC103220052

acidic fibroblast growth factor intracellular-binding protein

involved_in

GO_REF:0000118

NCBI chr14:33,730,781...33,732,322

LOC103222703

myosin regulatory light chain 12A

involved_in

(PMID:23382103)

NCBI chr18:62,496,372...62,504,835
Ensembl chr18:62,501,879...62,505,937

LOC103243509

neuroendocrine secretory protein 55

involved_in

(PMID:12719376)

PMID:12719376

NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192

LOC119618117

guanine nucleotide-binding protein G(s) subunit alpha

involved_in

GO_REF:0000107

Ensembl chr 2:5,233,874...5,249,192

METAP1

methionyl aminopeptidase 1

involved_in

(PMID:23382103)

NCBI chr 7:47,114,609...47,181,611
Ensembl chr 7:47,114,505...47,180,118

MYH9

myosin heavy chain 9

involved_in

(PMID:23382103)

NCBI chr19:18,985,709...19,093,304
Ensembl chr19:18,986,598...19,052,671

MYL9

myosin light chain 9

involved_in

(PMID:23382103)

NCBI chr 2:57,397,836...57,405,856
Ensembl chr 2:57,397,874...57,406,630

P2RY12

purinergic receptor P2Y12

involved_in

GO_REF:0000107

NCBI chr15:39,315,140...39,361,614
Ensembl chr15:39,359,612...39,360,637

PDGFRA

platelet derived growth factor receptor alpha

involved_in

GO_REF:0000107

NCBI chr 7:14,243,291...14,307,373
Ensembl chr 7:14,241,070...14,307,422

PDIA2

protein disulfide isomerase family A member 2

involved_in
acts_upstream_of_or_within

(PMID:28576878)

GO_REF:0000107

NCBI chr 5:229,523...233,298
Ensembl chr 5:229,607...233,200

PDIA3

protein disulfide isomerase family A member 3

acts_upstream_of_or_within
involved_in

(PMID:28576878)

GO_REF:0000107

NCBI chr26:39,273,982...39,300,170
Ensembl chr26:39,272,997...39,349,966

PDIA4

protein disulfide isomerase family A member 4

acts_upstream_of_or_within

(PMID:28576878)

NCBI chr21:117,574,932...117,601,896
Ensembl chr21:117,574,427...117,601,960

PEAR1

platelet endothelial aggregation receptor 1

involved_in

GO_REF:0000107

NCBI chr20:6,954,078...6,975,705
Ensembl chr20:6,954,600...6,965,292

PIP5K1C

phosphatidylinositol-4-phosphate 5-kinase type 1 gamma

acts_upstream_of_or_within

(PMID:23372168)

PMID:23372168

NCBI chr 6:3,389,575...3,454,108
Ensembl chr 6:3,389,056...3,453,836

PLEK

pleckstrin

involved_in

PMID:19190246 PMID:23382103

(PMID:23382103)
(PMID:19190246)

UniProt
BHF-UCL

NCBI chr14:38,689,387...38,769,090
Ensembl chr14:38,689,393...38,745,893

PPIA

peptidylprolyl isomerase A

involved_in

(PMID:24429998)

PMID:24429998

NCBI chr21:13,876,099...13,883,546
Ensembl chr21:13,876,099...13,883,462

PTPN6

protein tyrosine phosphatase non-receptor type 6

involved_in
acts_upstream_of_or_within

(PMID:23509158)

PMID:23509158

GO_REF:0000107

NCBI chr11:6,977,480...6,994,525
Ensembl chr11:6,984,710...6,994,545

RAP2B

RAP2B, member of RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr15:37,502,236...37,505,829
Ensembl chr15:37,504,830...37,505,378

SLC6A4

solute carrier family 6 member 4

involved_in

GO_REF:0000107

NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616

SLC7A11

solute carrier family 7 member 11

involved_in
acts_upstream_of_or_within

(PMID:8699821)

PMID:8699821

GO_REF:0000107

NCBI chr 7:85,149,810...85,225,061
Ensembl chr 7:85,154,068...85,225,144

STXBP1

syntaxin binding protein 1

involved_in

GO_REF:0000107

NCBI chr12:10,440,061...10,519,798
Ensembl chr12:10,439,801...10,519,777

STXBP3

syntaxin binding protein 3

involved_in

GO_REF:0000107

NCBI chr20:24,779,510...24,840,668
Ensembl chr20:24,779,271...24,840,643

TLN1

talin 1

involved_in

(PMID:23382103)

NCBI chr12:44,870,004...44,906,686
Ensembl chr12:44,876,643...44,907,072

TSPAN32

tetraspanin 32

acts_upstream_of_or_within
involved_in

(PMID:16720835)

PMID:16720835

GO_REF:0000107

NCBI chr 1:2,110,218...2,125,839
Ensembl chr 1:2,110,467...2,125,616

TUBB1

tubulin beta 1 class VI

involved_in

GO_REF:0000107

NCBI chr 2:5,115,488...5,123,089
Ensembl chr 2:5,117,326...5,122,845

TYRO3

TYRO3 protein tyrosine kinase

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr26:41,429,667...41,449,130
Ensembl chr26:41,429,556...41,449,175

UBASH3A

ubiquitin associated and SH3 domain containing A

NOT|acts_upstream_of_or_within

(PMID:27609517)

PMID:27609517

NCBI chr 2:86,279,762...86,330,281
Ensembl chr 2:86,280,198...86,332,756

UBASH3B

ubiquitin associated and SH3 domain containing B

acts_upstream_of_or_within
involved_in

(PMID:27609517)

PMID:27609517

GO_REF:0000107 GO_REF:0000118

NCBI chr 1:114,053,792...114,218,909
Ensembl chr 1:114,054,384...114,218,912

VCL

vinculin

involved_in

(PMID:23382103)

NCBI chr 9:57,253,219...57,375,947
Ensembl chr 9:57,255,166...57,376,028

WNT3A

Wnt family member 3A

acts_upstream_of_or_within
involved_in

(PMID:19901330)

PMID:19901330

GO_REF:0000107

NCBI chr25:1,664,316...1,675,006
Ensembl chr25:1,666,053...1,719,881

positive regulation of blood coagulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD36

CD36 molecule (CD36 blood group)

involved_in

GO_REF:0000107

NCBI chr21:68,214,875...68,309,336
Ensembl chr21:68,216,201...68,268,669

EMILIN2

elastin microfibril interfacer 2

involved_in

GO_REF:0000107

NCBI chr18:62,110,324...62,171,066
Ensembl chr18:62,110,616...62,170,384

ENPP4

ectonucleotide pyrophosphatase/phosphodiesterase 4

involved_in

GO_REF:0000107

NCBI chr17:26,102,687...26,117,142
Ensembl chr17:26,102,510...26,117,080

coagulation factor XII

involved_in

GO_REF:0000107

NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298

coagulation factor II thrombin receptor

acts_upstream_of_or_within
involved_in

(PMID:18305483)

PMID:18305483

GO_REF:0000107 GO_REF:0000118

NCBI chr 4:70,992,406...71,010,512
Ensembl chr 4:70,992,477...71,009,456

coagulation factor VII

NCBI chr 3:91,109,864...91,122,707
Ensembl chr 3:91,110,380...91,123,327

HPSE

heparanase

involved_in

GO_REF:0000107

NCBI chr 7:31,689,449...31,730,176
Ensembl chr 7:31,686,304...31,730,043

LOC103233689

thromboxane A2 receptor

NCBI chr 6:3,354,358...3,365,779
Ensembl chr 6:3,355,314...3,359,761

prothrombin

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr 1:18,589,658...18,627,459
Ensembl chr 1:18,620,215...18,627,511
Ensembl chr 1:18,620,215...18,627,511

NFE2L2

NFE2 like bZIP transcription factor 2

involved_in

GO_REF:0000107

NCBI chr10:62,789,647...62,825,651
Ensembl chr10:62,790,124...62,825,339

PRDX2

peroxiredoxin 2

involved_in

GO_REF:0000107

NCBI chr 6:11,484,452...11,489,067
Ensembl chr 6:11,481,784...11,489,051

S100A9

S100 calcium binding protein A9

involved_in

(PMID:24691441)

CACAO

PMID:24691441

NCBI chr20:10,391,965...10,395,216
Ensembl chr20:10,391,934...10,394,720

SERPINE1

serpin family E member 1

involved_in

GO_REF:0000107

NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202

ST3GAL4

ST3 beta-galactoside alpha-2,3-sialyltransferase 4

involved_in

GO_REF:0000107

NCBI chr 1:117,479,328...117,543,262
Ensembl chr 1:117,480,451...117,542,671

THBS1

thrombospondin 1

involved_in

GO_REF:0000107

NCBI chr26:43,410,693...43,427,816
Ensembl chr26:43,410,580...43,427,812

positive regulation of fibrinolysis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F11

coagulation factor XI

involved_in

GO_REF:0000107

NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155

coagulation factor XII

involved_in

GO_REF:0000107

NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298

KLKB1

kallikrein B1

involved_in

GO_REF:0000107

NCBI chr 7:132,143,514...132,173,189
Ensembl chr 7:132,144,420...132,173,187

plasminogen

involved_in

PMID:6438154 PMID:26667841

(PMID:26667841), (PMID:6438154)

AgBase

NCBI chr13:88,266,054...88,321,596
Ensembl chr13:88,268,198...88,322,644

positive regulation of glomerular filtration

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F2RL1

F2R like trypsin receptor 1

involved_in

PMID:12644441

NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005

GJA1

gap junction protein alpha 1

NCBI chr13:52,397,291...52,410,341
Ensembl chr13:52,396,109...52,410,339

LOC103214855

growth arrest-specific protein 6

involved_in

PMID:18374201

NCBI chr 3:91,720,871...91,762,712

PDGFB

platelet derived growth factor subunit B

involved_in

(PMID:15084468)

PMID:15084468

NCBI chr19:21,865,792...21,888,068
Ensembl chr19:21,863,768...21,886,395

positive regulation of lactation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

COMT

catechol-O-methyltransferase

RGD:11557979 (All species) (All species)

RGD

PMID:648869

NCBI chr19:5,775,829...5,803,260
Ensembl chr19:5,773,225...5,785,422

PRL

prolactin

involved_in

GO_REF:0000118

NCBI chr17:49,922,750...49,938,084
Ensembl chr17:49,928,321...49,938,631

XBP1

X-box binding protein 1

involved_in

(PMID:23623498)

PMID:23623498

NCBI chr19:11,670,605...11,677,168

positive regulation of mucus secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ALOX12B

arachidonate 12-lipoxygenase, 12R type

involved_in

GO_REF:0000107

NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934

ATG5

autophagy related 5

acts_upstream_of_or_within
involved_in

(PMID:24185898)

GO_REF:0000107

NCBI chr13:67,482,538...67,619,201
Ensembl chr13:67,482,595...67,617,902

ATG7

autophagy related 7

acts_upstream_of_or_within

(PMID:24185898)

NCBI chr22:47,187,305...47,571,309
Ensembl chr22:47,325,614...47,571,070

EGFR

epidermal growth factor receptor

NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239

LOC103224223

adenosine receptor A3

acts_upstream_of_or_within

(PMID:15240734)

PMID:15240734

NCBI chr20:22,043,367...22,127,103
Ensembl chr20:22,106,190...22,123,629

LOC103233451

cytochrome b-245 light chain

involved_in
acts_upstream_of_or_within

(PMID:24185898)

GO_REF:0000107

NCBI chr 5:74,023,134...74,030,793
Ensembl chr 5:74,023,082...74,030,750

MAP1LC3B

microtubule associated protein 1 light chain 3 beta

acts_upstream_of_or_within

(PMID:24185898)

NCBI chr 5:72,762,428...72,774,204
Ensembl chr 5:72,763,050...72,772,770

P2RY2

purinergic receptor P2Y2

involved_in
acts_upstream_of_or_within

(PMID:17728398)

InterPro
MGI

GO_REF:0000002

NCBI chr 1:64,461,929...64,481,429
Ensembl chr 1:64,479,642...64,480,775

PRKCE

protein kinase C epsilon

involved_in
acts_upstream_of_or_within

(PMID:17728398)

GO_REF:0000107

NCBI chr14:61,022,903...61,570,390
Ensembl chr14:61,026,017...61,242,343

PTGER3

prostaglandin E receptor 3

NCBI chr20:62,093,830...62,293,360
Ensembl chr20:62,095,458...62,174,959

PTGER4

prostaglandin E receptor 4

PMID:11991626 PMID:18254372

RGD

RGD:10003046 RGD:10003093

NCBI chr 4:39,440,697...39,453,983
Ensembl chr 4:39,440,276...39,454,004

SYTL2

synaptotagmin like 2

involved_in

(PMID:16716193)

PMID:16716193

NCBI chr 1:76,937,076...77,061,895

positive regulation of pancreatic amylase secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

VAMP8

vesicle associated membrane protein 8

acts_upstream_of_or_within

(PMID:18535671)

PMID:18535671

NCBI chr14:21,575,057...21,580,054
Ensembl chr14:21,575,161...21,579,820

positive regulation of pancreatic amylase secretion by cholecystokinin signaling pathway

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

cholecystokinin

NCBI chr22:3,698,192...3,705,443
Ensembl chr22:3,698,173...3,704,956

positive regulation of pancreatic juice secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NPR3

natriuretic peptide receptor 3

NCBI chr 4:31,984,712...32,062,593
Ensembl chr 4:31,986,217...32,062,199

NR1H2

nuclear receptor subfamily 1 group H member 2

involved_in

GO_REF:0000107

NCBI chr 6:43,438,428...43,445,190
Ensembl chr 6:43,437,950...43,446,063

SCT

secretin

involved_in

RGD
TreeGrafter

PMID:11123201

GO_REF:0000118 RGD:9590235

NCBI chr 1:444,487...445,535
Ensembl chr 1:444,601...445,339

SPINK1

serine peptidase inhibitor Kazal type 1

NCBI chr23:50,365,686...50,373,300
Ensembl chr23:50,365,269...50,372,814

positive regulation of pancreatic trypsinogen secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MMP13

matrix metallopeptidase 13

NCBI chr 1:94,322,473...94,370,665
Ensembl chr 1:94,322,979...94,334,747

positive regulation of platelet activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

glycoprotein Ib platelet subunit alpha

involved_in

(PMID:1939645)

PMID:1939645

NCBI chr16:4,412,693...4,415,841

glycoprotein Ib platelet subunit alpha

involved_in

GO_REF:0000107

Ensembl chr16:4,413,307...4,415,475

GP1BB

glycoprotein Ib platelet subunit beta

involved_in

(PMID:1939645)

PMID:1939645

NCBI chr19:6,020,618...6,021,646

glycoprotein V platelet

involved_in

GO_REF:0000107

NCBI chr15:88,491,781...88,495,601
Ensembl chr15:88,492,336...88,494,018

GP9

glycoprotein IX platelet

involved_in

GO_REF:0000107

NCBI chr22:52,000,620...52,013,570
Ensembl chr22:52,000,758...52,001,291

JAK2

Janus kinase 2

acts_upstream_of_or_within
involved_in

(PMID:31145836)

ARUK-UCL
Ensembl

GO_REF:0000107

NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710

podoplanin

NCBI chr20:118,644,060...118,679,508
Ensembl chr20:118,644,051...118,679,311

PEAR1

platelet endothelial aggregation receptor 1

involved_in

GO_REF:0000107

NCBI chr20:6,954,078...6,975,705
Ensembl chr20:6,954,600...6,965,292

PLA2G4A

phospholipase A2 group IVA

involved_in

GO_REF:0000107

NCBI chr25:42,443,480...42,590,895
Ensembl chr25:42,443,385...42,590,431

PLEK

pleckstrin

involved_in

(PMID:19190246)

PMID:19190246

NCBI chr14:38,689,387...38,769,090
Ensembl chr14:38,689,393...38,745,893

PTPRJ

protein tyrosine phosphatase receptor type J

involved_in

GO_REF:0000107

NCBI chr 1:17,137,896...17,328,836
Ensembl chr 1:17,135,907...17,328,590

SELP

selectin P

involved_in

GO_REF:0000107

NCBI chr25:59,420,910...59,465,140
Ensembl chr25:59,433,333...59,462,598

SVEP1

sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1

involved_in

GO_REF:0000107

NCBI chr12:28,806,583...29,183,167
Ensembl chr12:28,959,222...29,181,871

TLR4

toll like receptor 4

involved_in

(PMID:16514062)

PMID:16514062

NCBI chr12:21,873,762...21,885,562
Ensembl chr12:21,871,773...21,885,515

positive regulation of platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CTSG

cathepsin G

involved_in

GO_REF:0000107

NCBI chr24:1,518,004...1,521,980
Ensembl chr24:1,518,119...1,520,709

EMILIN2

elastin microfibril interfacer 2

involved_in

GO_REF:0000107

NCBI chr18:62,110,324...62,171,066
Ensembl chr18:62,110,616...62,170,384

F11R

F11 receptor

involved_in

GO_REF:0000107

NCBI chr20:2,966,019...2,986,177
Ensembl chr20:2,966,164...2,984,269

HTR2A

5-hydroxytryptamine receptor 2A

NCBI chr 3:24,820,029...24,884,472
Ensembl chr 3:24,820,035...24,883,432

IL6

interleukin 6

involved_in
acts_upstream_of

(PMID:31145836)

Ensembl
ARUK-UCL

GO_REF:0000107

NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237

IL6R

interleukin 6 receptor

acts_upstream_of

(PMID:31145836)

ARUK-UCL

NCBI chr20:9,345,723...9,418,963
Ensembl chr20:9,361,152...9,396,610

JAK2

Janus kinase 2

involved_in
acts_upstream_of

(PMID:31145836)

Ensembl
ARUK-UCL

GO_REF:0000107

NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710

MFSD2B

MFSD2 lysolipid transporter B, sphingolipid

involved_in

(PMID:33863882)

PMID:33863882

NCBI chr14:83,649,816...83,663,295

MMRN1

multimerin 1

involved_in

GO_REF:0000107

NCBI chr 7:38,233,562...38,310,006
Ensembl chr 7:38,250,942...38,309,972

PDPN

podoplanin

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr20:118,644,060...118,679,508
Ensembl chr20:118,644,051...118,679,311

positive regulation of renal water transport

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

INPP5K

inositol polyphosphate-5-phosphatase K

involved_in

GO_REF:0000107

NCBI chr16:1,171,059...1,192,241
Ensembl chr16:1,170,899...1,191,965

positive regulation of saliva secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1 (Colton blood group)

involved_in

GO_REF:0000107

NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728

NEGR1

neuronal growth regulator 1

acts_upstream_of_or_within

(PMID:37216094)

PMID:37216094

NCBI chr20:60,848,712...61,731,563

NEGR1

neuronal growth regulator 1

involved_in

GO_REF:0000107

Ensembl chr20:61,200,832...61,549,607

PPP3CA

protein phosphatase 3 catalytic subunit alpha

involved_in

GO_REF:0000107

NCBI chr 7:49,149,044...49,478,796
Ensembl chr 7:49,148,933...49,321,013

TAC4

tachykinin precursor 4

acts_upstream_of_or_within

(PMID:11062498)

PMID:11062498

NCBI chr16:43,489,184...43,500,908
Ensembl chr16:43,490,160...43,499,820

positive regulation of urine volume

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA2A

adenosine A2a receptor

in renal medulla

NCBI chr19:7,691,678...7,706,781
Ensembl chr19:7,691,536...7,706,926

betacellulin

NCBI chr 7:23,283,269...23,333,373
Ensembl chr 7:23,281,862...23,308,287

DRD2

dopamine receptor D2

involved_in
acts_upstream_of_or_within

(PMID:11566895)

PMID:11566895

GO_REF:0000107

NCBI chr 1:104,774,632...104,843,417
Ensembl chr 1:104,774,180...104,842,736

EDN1

endothelin 1

acts_upstream_of_or_within
involved_in

(PMID:15632412)

PMID:15632412

GO_REF:0000107

NCBI chr17:59,854,186...59,861,319
Ensembl chr17:59,853,699...59,861,198

EDNRB

endothelin receptor type B

NCBI chr 3:56,969,493...56,993,719
Ensembl chr 3:56,969,101...56,992,731

GNAI2

G protein subunit alpha i2

NCBI chr22:11,623,394...11,646,464
Ensembl chr22:11,623,408...11,647,191

HAS2

hyaluronan synthase 2

involved_in

PMID:19635555

NCBI chr 8:116,199,516...116,228,705
Ensembl chr 8:116,200,799...116,228,788

HYAL2

hyaluronidase 2

involved_in

PMID:19635555

NCBI chr22:11,704,422...11,710,013
Ensembl chr22:11,703,790...11,709,454

INPP5K

inositol polyphosphate-5-phosphatase K

involved_in

GO_REF:0000107

NCBI chr16:1,171,059...1,192,241
Ensembl chr16:1,170,899...1,191,965

NPPB

natriuretic peptide B

NCBI chr20:119,930,931...119,933,391
Ensembl chr20:119,932,021...119,933,197

NPR3

natriuretic peptide receptor 3

involved_in

GO_REF:0000107

NCBI chr 4:31,984,712...32,062,593
Ensembl chr 4:31,986,217...32,062,199

PTGER3

prostaglandin E receptor 3

acts_upstream_of_or_within

(PMID:9843913)

PMID:9843913

NCBI chr20:62,093,830...62,293,360
Ensembl chr20:62,095,458...62,174,959

PTGER4

prostaglandin E receptor 4

NCBI chr 4:39,440,697...39,453,983
Ensembl chr 4:39,440,276...39,454,004

regulation of blood coagulation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apolipoprotein H

acts_upstream_of_or_within

(PMID:11145969)

PMID:11145969

NCBI chr16:55,209,142...55,231,176

apolipoprotein H

involved_in

GO_REF:0000107

Ensembl chr16:55,209,156...55,231,076

CAV1

caveolin 1

involved_in

GO_REF:0000107

NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627

EPHB2

EPH receptor B2

involved_in

GO_REF:0000107

NCBI chr20:109,747,883...109,954,936
Ensembl chr20:109,746,925...109,890,777

F11

coagulation factor XI

acts_upstream_of_or_within
involved_in

(PMID:16533887)

PMID:16533887

GO_REF:0000107

NCBI chr 7:132,180,026...132,207,081
Ensembl chr 7:132,180,336...132,208,155

coagulation factor II thrombin receptor

involved_in

GO_REF:0000107

NCBI chr 4:70,992,406...71,010,512
Ensembl chr 4:70,992,477...71,009,456

F2RL1

F2R like trypsin receptor 1

involved_in

GO_REF:0000107

NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005

FOXA2

forkhead box A2

involved_in

GO_REF:0000107

NCBI chr 2:51,577,127...51,585,168
Ensembl chr 2:51,577,833...51,580,297

histidine rich glycoprotein

involved_in

GO_REF:0000107

NCBI chr15:2,753,819...2,766,946
Ensembl chr15:2,753,810...2,766,478

VKORC1

vitamin K epoxide reductase complex subunit 1

NCBI chr 5:27,778,553...27,782,639
Ensembl chr 5:27,776,416...27,782,640

regulation of blood volume by renal aldosterone

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CYP11B1

cytochrome P450 family 11 subfamily B member 1

involved_in

GO_REF:0000107

NCBI chr 8:137,125,409...137,132,267

CYP11B2

cytochrome P450 family 11 subfamily B member 2

involved_in

GO_REF:0000107

NCBI chr 8:137,160,919...137,168,332
Ensembl chr 8:137,162,325...137,168,350

HSD11B2

hydroxysteroid 11-beta dehydrogenase 2

NCBI chr 5:60,017,967...60,040,959
Ensembl chr 5:60,019,434...60,025,353

NR3C2

nuclear receptor subfamily 3 group C member 2

involved_in

(PMID:24206662)

PMID:24206662

NCBI chr 7:94,574,010...94,935,348

regulation of fibrinolysis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apolipoprotein H

involved_in

(PMID:16480936)

PMID:16480936

NCBI chr16:55,209,142...55,231,176

apolipoprotein H

involved_in

GO_REF:0000107

Ensembl chr16:55,209,156...55,231,076

regulation of glomerular filtration

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA1

adenosine A1 receptor

acts_upstream_of_or_within
involved_in

(PMID:15283758)

PMID:15283758

GO_REF:0000107

NCBI chr25:26,180,898...26,221,424
Ensembl chr25:26,182,446...26,220,776

CORO2B

coronin 2B

acts_upstream_of_or_within
involved_in

(PMID:29162887)

PMID:29162887

GO_REF:0000107

NCBI chr26:14,746,497...14,909,483
Ensembl chr26:14,746,379...14,895,951

EMP2

epithelial membrane protein 2

involved_in

GO_REF:0000107

NCBI chr 5:10,013,722...10,060,880
Ensembl chr 5:10,014,121...10,028,949

PTPRO

protein tyrosine phosphatase receptor type O

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr11:15,225,375...15,494,559
Ensembl chr11:15,392,926...15,495,807

regulation of hemostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TPH1

tryptophan hydroxylase 1

involved_in

(PMID:14697203)

PMID:14697203

NCBI chr 1:46,921,682...46,947,906

TPH1

tryptophan hydroxylase 1

involved_in

GO_REF:0000107

Ensembl chr 1:46,932,614...46,949,943

regulation of lactation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

OAS2

2'-5'-oligoadenylate synthetase 2

involved_in

GO_REF:0000107

NCBI chr11:108,218,645...108,251,485
Ensembl chr11:108,218,665...108,252,836

regulation of mucus secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NLRP6

NLR family pyrin domain containing 6

acts_upstream_of_or_within
involved_in

(PMID:24581500)

PMID:24581500

GO_REF:0000107

NCBI chr 1:92,213...99,919

regulation of platelet activation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FCER1G

Fc fragment of IgE receptor Ig

involved_in

GO_REF:0000118

NCBI chr20:2,763,412...2,767,774
Ensembl chr20:2,763,417...2,767,248

FUNDC2

FUN14 domain containing 2

involved_in

(PMID:30576423)

PMID:30576423

NCBI chr X:129,315,315...129,342,395
Ensembl chr X:129,315,465...129,342,193

GNAQ

G protein subunit alpha q

involved_in

(PMID:9296496)

PMID:9296496

NCBI chr12:88,666,375...88,988,989
Ensembl chr12:88,670,424...88,871,154

histidine rich glycoprotein

involved_in

GO_REF:0000118

NCBI chr15:2,753,819...2,766,946
Ensembl chr15:2,753,810...2,766,478

SYK

spleen associated tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr12:101,254,085...101,374,724
Ensembl chr12:101,260,061...101,349,856

TEC

tec protein tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr27:1,982,549...2,118,533
Ensembl chr27:2,024,719...2,117,763

regulation of platelet aggregation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

LYN

LYN proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959

PRKCA

protein kinase C alpha

involved_in

GO_REF:0000107

NCBI chr16:54,638,548...55,144,372
Ensembl chr16:54,642,729...54,948,256

PRKCQ

protein kinase C theta

involved_in

GO_REF:0000107

NCBI chr 9:6,532,438...6,675,708
Ensembl chr 9:6,532,319...6,621,487

SYK

spleen associated tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr12:101,254,085...101,374,724
Ensembl chr12:101,260,061...101,349,856

VPS33B

VPS33B late endosome and lysosome associated

involved_in

GO_REF:0000107

NCBI chr29:8,838,289...8,862,914
Ensembl chr29:8,838,735...8,862,977

regulation of saliva secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FGF10

fibroblast growth factor 10

involved_in

GO_REF:0000107

NCBI chr 4:43,080,387...43,163,355
Ensembl chr 4:43,081,831...43,163,432

OPRK1

opioid receptor kappa 1

involved_in

(PMID:9463367)

PMID:9463367

NCBI chr 8:49,337,308...49,364,724
Ensembl chr 8:49,341,427...49,362,947

regulation of urine volume

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADM

adrenomedullin

involved_in

GO_REF:0000107

NCBI chr 1:54,518,359...54,520,683
Ensembl chr 1:54,518,358...54,520,686

ADM5

adrenomedullin 5 (putative)

involved_in

(PMID:18434369)

PMID:18434369

NCBI chr 6:42,863,451...42,865,314

LOC103226928

aldo-keto reductase family 1 member B1

acts_upstream_of_or_within

(PMID:16449351)

PMID:16449351

NCBI chr21:103,060,018...103,076,844
Ensembl chr21:103,059,991...103,077,341

TRPV5

transient receptor potential cation channel subfamily V member 5

involved_in

GO_REF:0000107

NCBI chr21:111,787,214...111,816,893
Ensembl chr21:111,787,694...111,811,847

UMOD

uromodulin

acts_upstream_of_or_within
involved_in

(PMID:29145399), (PMID:29357410)

PMID:29145399 PMID:29357410

GO_REF:0000107

NCBI chr 5:18,620,927...18,641,312
Ensembl chr 5:18,619,895...18,638,719

renal water absorption

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1 (Colton blood group)

involved_in
acts_upstream_of_or_within

(PMID:10021457), (PMID:10662735), (PMID:10724035), (PMID:10795927), (PMID:11035042), (PMID:12133842), (PMID:16525162), (PMID:9468475)
(PMID:10662735)
(PMID:11035042)
(PMID:15998844)

PMID:9468475 PMID:10021457 PMID:10662735 PMID:10724035 PMID:10795927 More...

GO_REF:0000107

NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728

AQP3

aquaporin 3 (Gill blood group)

acts_upstream_of_or_within

(PMID:11035042)
(PMID:10795927), (PMID:11035042)

PMID:10795927 PMID:11035042

NCBI chr12:46,817,790...46,825,154

AQP3

aquaporin 3 (Gill blood group)

involved_in

GO_REF:0000107

Ensembl chr12:46,818,779...46,825,148

AQP4

aquaporin 4

acts_upstream_of_or_within

(PMID:10662735)
(PMID:10662735), (PMID:10795927)

PMID:10662735 PMID:10795927

NCBI chr18:53,729,143...53,742,916
Ensembl chr18:53,729,186...53,743,156

AQP7

aquaporin 7

involved_in
acts_upstream_of_or_within

(PMID:15998844)

PMID:15998844

GO_REF:0000107

NCBI chr12:46,866,519...46,886,525

HAS2

hyaluronan synthase 2

involved_in

PMID:19635555

NCBI chr 8:116,199,516...116,228,705
Ensembl chr 8:116,200,799...116,228,788

HYAL2

hyaluronidase 2

involved_in

PMID:19635555

NCBI chr22:11,704,422...11,710,013
Ensembl chr22:11,703,790...11,709,454

cystinosin

NCBI chr16:3,138,716...3,164,512
Ensembl chr16:3,138,734...3,164,625

MLLT6

MLLT6, PHD finger containing

involved_in
acts_upstream_of_or_within

(PMID:21546577)

PMID:21546577

GO_REF:0000107

NCBI chr16:67,466,001...67,490,019
Ensembl chr16:67,465,913...67,490,251

SCTR

secretin receptor

involved_in

(PMID:17283064)

PMID:17283064

NCBI chr10:10,802,156...10,883,884
Ensembl chr10:10,833,507...10,883,605

renal water homeostasis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCY6

adenylate cyclase 6

involved_in

(PMID:20466003)

PMID:20466003

NCBI chr11:45,006,220...45,031,481
Ensembl chr11:45,005,637...45,025,501

AKAP11

A-kinase anchoring protein 11

involved_in
acts_upstream_of_or_within

(PMID:27402760)

PMID:27402760

GO_REF:0000107

NCBI chr 3:20,447,394...20,498,604
Ensembl chr 3:20,462,176...20,494,670

AQP2

aquaporin 2

involved_in
acts_upstream_of_or_within

(PMID:27402760)

PMID:27402760

GO_REF:0000107

NCBI chr11:46,179,783...46,188,631
Ensembl chr11:46,180,387...46,188,712

ATP6V1B1

ATPase H+ transporting V1 subunit B1

involved_in
acts_upstream_of_or_within

(PMID:24051376)

PMID:24051376

GO_REF:0000107

NCBI chr14:36,149,074...36,179,145
Ensembl chr14:36,149,006...36,177,671

LOC103226928

aldo-keto reductase family 1 member B1

acts_upstream_of_or_within

(PMID:16449351)

PMID:16449351

NCBI chr21:103,060,018...103,076,844
Ensembl chr21:103,059,991...103,077,341

UMOD

uromodulin

acts_upstream_of_or_within
involved_in

(PMID:15522986)

PMID:15522986

GO_REF:0000107

NCBI chr 5:18,620,927...18,641,312
Ensembl chr 5:18,619,895...18,638,719

WFS1

wolframin ER transmembrane glycoprotein

involved_in

GO_REF:0000107

NCBI chr27:42,404,028...42,437,988
Ensembl chr27:42,404,084...42,438,005

renal water transport

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

aquaporin 1 (Colton blood group)

involved_in

GO_REF:0000107 GO_REF:0000118

NCBI chr21:27,456,553...27,473,196
Ensembl chr21:27,456,259...27,470,728

AQP2

aquaporin 2

involved_in
acts_upstream_of_or_within

(PMID:3184310)

PMID:3184310

GO_REF:0000107

NCBI chr11:46,179,783...46,188,631
Ensembl chr11:46,180,387...46,188,712

AQP6

aquaporin 6

involved_in

(PMID:8812490)

PMID:8812490

NCBI chr11:46,199,907...46,207,010

AQP6

aquaporin 6

involved_in

GO_REF:0000107

Ensembl chr11:46,202,677...46,206,161

saliva secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AQP5

aquaporin 5

involved_in
acts_upstream_of_or_within

(PMID:10400615), (PMID:10795927), (PMID:15647389)

PMID:10400615 PMID:10795927 PMID:15647389

GO_REF:0000107

NCBI chr11:46,190,504...46,195,461

CHRM1

cholinergic receptor muscarinic 1

involved_in

GO_REF:0000002

NCBI chr 1:10,978,464...10,991,650
Ensembl chr 1:10,989,207...10,990,589

CHRM3

cholinergic receptor muscarinic 3

involved_in
acts_upstream_of_or_within

(PMID:10944224)

InterPro
MGI

PMID:10944224

GO_REF:0000002

NCBI chr25:76,772,212...77,009,433
Ensembl chr25:77,001,477...77,003,249

KCNMA1

potassium calcium-activated channel subfamily M alpha 1

acts_upstream_of_or_within

(PMID:16873365)

PMID:16873365

NCBI chr 9:53,727,790...54,557,252
Ensembl chr 9:54,182,910...54,554,716

KCNN4

potassium calcium-activated channel subfamily N member 4

acts_upstream_of_or_within

(PMID:16873365)

PMID:16873365

NCBI chr 6:37,289,088...37,316,850

NKX2-3

NK2 homeobox 3

involved_in
acts_upstream_of_or_within

(PMID:38311164)

PMID:38311164

GO_REF:0000107

NCBI chr 9:92,590,342...92,594,749
Ensembl chr 9:92,591,375...92,594,842

SLC4A9

solute carrier family 4 member 9

involved_in

GO_REF:0000107

NCBI chr23:43,009,857...43,026,123
Ensembl chr23:43,010,484...43,026,689

TRPC1

transient receptor potential cation channel subfamily C member 1

acts_upstream_of_or_within

(PMID:17956991)

PMID:17956991

NCBI chr15:47,827,295...47,909,207
Ensembl chr15:47,827,247...47,909,202

tear secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FGF10

fibroblast growth factor 10

involved_in

GO_REF:0000107

NCBI chr 4:43,080,387...43,163,355
Ensembl chr 4:43,081,831...43,163,432

LACRT

lacritin

involved_in

PMID:25034600 PMID:25481446

(PMID:25034600), (PMID:25481446)

FlyBase

NCBI chr11:50,746,437...50,752,631

LACRT

lacritin

involved_in

GO_REF:0000107

Ensembl chr11:50,746,518...50,750,513

PRICKLE1

prickle planar cell polarity protein 1

involved_in