BCAT2 (branched chain amino acid transaminase 2) - Rat Genome Database

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Gene: BCAT2 (branched chain amino acid transaminase 2) Chlorocebus sabaeus
Analyze
Symbol: BCAT2
Name: branched chain amino acid transaminase 2
RGD ID: 18649942
Description: ENCODES a protein that exhibits branched-chain-amino-acid transaminase activity (ortholog); INVOLVED IN branched-chain amino acid catabolic process (ortholog); branched-chain amino acid metabolic process (ortholog); cellular response to leukemia inhibitory factor (ortholog); PARTICIPATES IN valine, leucine and isoleucine biosynthetic pathway; valine, leucine and isoleucine degradation pathway; ASSOCIATED WITH hypervalinemia and hyperleucine-isoleucinemia (ortholog); maple syrup urine disease (ortholog); pre-malignant neoplasm (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: branched-chain-amino-acid aminotransferase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,031,003 - 42,051,770 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,030,984 - 42,049,050 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607321,910,508 - 21,927,833 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BCAT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,031,003 - 42,051,770 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,030,984 - 42,049,050 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607321,910,508 - 21,927,833 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
BCAT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,795,064 - 48,811,029 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,795,062 - 48,811,029 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,298,321 - 49,314,286 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361953,990,131 - 54,006,113 (-)NCBINCBI36Build 36hg18NCBI36
Build 341953,990,131 - 54,006,113NCBI
Celera1946,166,129 - 46,182,134 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,677,853 - 45,693,853 (-)NCBIHuRef
CHM1_11949,300,194 - 49,316,125 (-)NCBICHM1_1
T2T-CHM13v2.01951,790,087 - 51,806,051 (-)NCBIT2T-CHM13v2.0
Bcat2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,219,773 - 45,239,134 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,219,577 - 45,239,135 (+)EnsemblGRCm39 Ensembl
GRCm38745,568,967 - 45,589,710 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,570,153 - 45,589,711 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,825,733 - 52,845,078 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,438,405 - 45,457,750 (+)NCBIMGSCv36mm8
Celera741,023,580 - 41,045,483 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.36NCBI
Bcat2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,175,157 - 105,196,474 (+)NCBIGRCr8
mRatBN7.2196,040,407 - 96,060,008 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl196,042,625 - 96,060,007 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,428,109 - 101,445,450 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,900,801 - 109,918,146 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,191,189 - 103,208,524 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,553,900 - 101,572,103 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,554,642 - 101,572,080 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,633,422 - 102,650,883 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,038,287 - 96,055,622 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1196,116,397 - 96,133,732 (+)NCBI
Celera190,298,174 - 90,315,510 (+)NCBICelera
Cytogenetic Map1q22NCBI
Bcat2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,785,253 - 1,797,899 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,785,253 - 1,796,838 (+)NCBIChiLan1.0ChiLan1.0
BCAT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22054,897,417 - 54,914,501 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,823,445 - 56,840,050 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,793,433 - 45,809,546 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,945,156 - 54,962,887 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,945,157 - 54,962,887 (+)Ensemblpanpan1.1panPan2
BCAT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,539,125 - 107,549,286 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,538,465 - 107,549,234 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,061,565 - 107,071,746 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01108,063,749 - 108,073,941 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1108,063,615 - 108,073,930 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,730,663 - 107,740,841 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,377,548 - 107,387,729 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,213,156 - 108,223,338 (+)NCBIUU_Cfam_GSD_1.0
Bcat2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,247,666 - 21,259,021 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,864,231 - 2,890,018 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,865,804 - 2,890,038 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCAT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,107,684 - 54,142,790 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,107,682 - 54,123,595 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,855,038 - 49,870,815 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Bcat2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,134,590 - 5,147,290 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,132,667 - 5,147,099 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000000827   ⟹   ENSCSAP00000015237
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl642,030,984 - 42,049,050 (-)Ensembl
RefSeq Acc Id: XM_007997469   ⟹   XP_007995660
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1642,031,003 - 42,051,463 (-)NCBI
Vero_WHO_p1.0NW_02366607321,910,508 - 21,927,605 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007997470   ⟹   XP_007995661
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1642,031,003 - 42,051,768 (-)NCBI
Vero_WHO_p1.0NW_02366607321,910,508 - 21,927,833 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037991354   ⟹   XP_037847282
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607321,910,508 - 21,927,595 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007995660 (Get FASTA)   NCBI Sequence Viewer  
  XP_007995661 (Get FASTA)   NCBI Sequence Viewer  
  XP_037847282 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015237
  ENSCSAP00000015237.1
RefSeq Acc Id: XP_007995661   ⟸   XM_007997470
- Peptide Label: isoform X2
RefSeq Acc Id: XP_007995660   ⟸   XM_007997469
- Peptide Label: isoform X1
Ensembl Acc Id: ENSCSAP00000015237   ⟸   ENSCSAT00000000827
RefSeq Acc Id: XP_037847282   ⟸   XM_037991354
- Peptide Label: isoform X3
- UniProtKB: A0A0D9S2Z8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002809 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000827.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.10.10 UniProtKB/TrEMBL
  3.30.470.10 UniProtKB/TrEMBL
InterPro Aminotrans_IV UniProtKB/TrEMBL
  Aminotrans_IV_CS UniProtKB/TrEMBL
  Aminotransferase-like UniProtKB/TrEMBL
  B_amino_transII UniProtKB/TrEMBL
  BCAT-like_C UniProtKB/TrEMBL
  BCAT-like_N UniProtKB/TrEMBL
  BCAT_family UniProtKB/TrEMBL
NCBI Gene BCAT2 ENTREZGENE
PANTHER BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR11825 UniProtKB/TrEMBL
Pfam Aminotran_4 UniProtKB/TrEMBL
PIRSF BCAT1 UniProtKB/TrEMBL
PROSITE AA_TRANSFER_CLASS_4 UniProtKB/TrEMBL
Superfamily-SCOP SSF56752 UniProtKB/TrEMBL
UniProt A0A0D9S2Z8 ENTREZGENE, UniProtKB/TrEMBL