RASA3 (RAS p21 protein activator 3) - Rat Genome Database

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Gene: RASA3 (RAS p21 protein activator 3) Chlorocebus sabaeus
Analyze
Symbol: RASA3
Name: RAS p21 protein activator 3
RGD ID: 18777818
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); intracellularly gated calcium channel activity (inferred); metal ion binding (inferred); INVOLVED IN cellular response to heat (ortholog); ASSOCIATED WITH aplastic anemia (ortholog); Dwarfism (ortholog); factor X deficiency (ortholog); FOUND IN cytoplasmic side of plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras GTPase-activating protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1391,848,158 - 91,974,675 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl391,848,160 - 91,974,555 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604649,138,040 - 49,271,270 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
RASA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1391,848,158 - 91,974,675 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl391,848,160 - 91,974,555 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604649,138,040 - 49,271,270 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
RASA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813113,977,783 - 114,132,623 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13113,977,783 - 114,132,623 (-)EnsemblGRCh38hg38GRCh38
GRCh3713114,747,194 - 114,898,098 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3613113,765,296 - 113,916,197 (-)NCBINCBI36Build 36hg18NCBI36
Build 3413113,765,296 - 113,916,197NCBI
Celera1395,423,074 - 95,573,004 (-)NCBICelera
Cytogenetic Map13q34NCBI
HuRef1395,016,746 - 95,162,033 (-)NCBIHuRef
CHM1_113114,715,940 - 114,865,735 (-)NCBICHM1_1
T2T-CHM13v2.013113,188,423 - 113,340,668 (-)NCBIT2T-CHM13v2.0
Rasa3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39813,617,218 - 13,727,590 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl813,616,948 - 13,727,603 (-)EnsemblGRCm39 Ensembl
GRCm38813,567,218 - 13,677,587 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl813,566,948 - 13,677,603 (-)EnsemblGRCm38mm10GRCm38
MGSCv37813,567,218 - 13,677,587 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36813,567,195 - 13,677,549 (-)NCBIMGSCv36mm8
Celera813,734,036 - 13,844,447 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map86.29NCBI
Rasa3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81682,557,556 - 82,671,527 (+)NCBIGRCr8
mRatBN7.21675,855,360 - 75,969,349 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1675,855,265 - 75,970,804 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1681,135,990 - 81,249,957 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01684,588,959 - 84,702,928 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01679,837,128 - 79,951,690 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01681,320,090 - 81,434,239 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1681,318,633 - 81,434,363 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01680,808,492 - 80,922,641 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41680,710,463 - 80,824,220 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11680,815,596 - 80,825,940 (+)NCBI
Celera1673,663,562 - 73,777,478 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
Rasa3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955404141,060 - 225,572 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955404140,906 - 225,278 (+)NCBIChiLan1.0ChiLan1.0
RASA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214115,451,429 - 115,622,482 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113114,144,769 - 114,304,323 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01395,036,382 - 95,195,480 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113114,123,816 - 114,271,066 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13114,123,816 - 114,271,066 (-)Ensemblpanpan1.1panPan2
RASA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12261,093,762 - 61,202,209 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2261,095,044 - 61,202,152 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2260,805,357 - 60,913,843 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02261,780,849 - 61,889,450 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2261,780,855 - 61,889,451 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12261,218,315 - 61,326,769 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02261,225,625 - 61,334,098 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02261,252,037 - 61,360,858 (-)NCBIUU_Cfam_GSD_1.0
Rasa3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945195,992,373 - 196,074,750 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493703040,116 - 122,490 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493703040,123 - 122,478 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1178,951,019 - 79,027,900 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11178,951,017 - 79,027,991 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21186,685,993 - 86,763,496 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Rasa3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624793257,661 - 334,981 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624793209,616 - 336,304 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 2 20 14
Low 34 46
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000015488   ⟹   ENSCSAP00000013427
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl391,848,160 - 91,974,555 (-)Ensembl
RefSeq Acc Id: XM_007961021   ⟹   XP_007959212
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1391,848,158 - 91,974,675 (-)NCBI
Vero_WHO_p1.0NW_02366604649,138,040 - 49,271,270 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007961024   ⟹   XP_007959215
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1391,848,158 - 91,929,369 (-)NCBI
Vero_WHO_p1.0NW_02366604649,138,040 - 49,225,870 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038007934   ⟹   XP_037863862
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604649,138,040 - 49,271,255 (-)NCBI
Protein Sequences
Protein RefSeqs XP_007959212 (Get FASTA)   NCBI Sequence Viewer  
  XP_007959215 (Get FASTA)   NCBI Sequence Viewer  
  XP_037863862 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013427
  ENSCSAP00000013427.1
Reference Protein Sequences
RefSeq Acc Id: XP_007959212   ⟸   XM_007961021
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RXT8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007959215   ⟸   XM_007961024
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCSAP00000013427   ⟸   ENSCSAT00000015488
RefSeq Acc Id: XP_037863862   ⟸   XM_038007934
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017394 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015488.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  Ras_GTPase UniProtKB/TrEMBL
  RASA3_PH UniProtKB/TrEMBL
  RasGAP_CS UniProtKB/TrEMBL
  RasGAP_dom UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  Znf_Btk_motif UniProtKB/TrEMBL
KEGG Report csab:103214860 UniProtKB/TrEMBL
NCBI Gene RASA3 ENTREZGENE
PANTHER PTHR10194 UniProtKB/TrEMBL
  RAS GTPASE-ACTIVATING PROTEIN 3 UniProtKB/TrEMBL
Pfam BTK UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  RasGAP UniProtKB/TrEMBL
PRINTS TECBTKDOMAIN UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_1 UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_2 UniProtKB/TrEMBL
  ZF_BTK UniProtKB/TrEMBL
SMART BTK UniProtKB/TrEMBL
  RasGAP UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48350 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
UniProt A0A0D9RXT8 ENTREZGENE, UniProtKB/TrEMBL