GP9 (glycoprotein IX platelet) - Rat Genome Database

Name: GP9
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: GP9 (glycoprotein IX platelet) Chlorocebus sabaeus

Analyze

Symbol:

GP9

Name:

glycoprotein IX platelet

RGD ID:

18359553

Description:

INVOLVED IN blood coagulation (inferred); blood coagulation, intrinsic pathway (inferred); megakaryocyte development (inferred); PARTICIPATES IN platelet aggregation pathway; ASSOCIATED WITH alkaptonuria (ortholog); Bernard-Soulier syndrome (ortholog); Bernard-Soulier Syndrome, Type C (ortholog); FOUND IN glycoprotein Ib-IX-V complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

platelet glycoprotein IX

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GP9 (glycoprotein IX platelet)	NCBI	Ortholog
Mus musculus (house mouse):	Gp9 (glycoprotein 9 platelet)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Gp9 (glycoprotein IX (platelet))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gp9 (glycoprotein IX platelet)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GP9 (glycoprotein IX platelet)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GP9 (glycoprotein IX platelet)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gp9 (glycoprotein IX platelet)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GP9 (glycoprotein IX platelet)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gp9 (glycoprotein IX platelet)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	52,000,620 - 52,013,570 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	52,000,758 - 52,001,291 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	114,366,247 - 114,367,885 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alkaptonuria (ISO)

Bernard-Soulier syndrome (ISO)

Bernard-Soulier Syndrome, Type C (ISO)

genetic disease (ISO)

immunodeficiency 21 (ISO)

Primary Lymphedema with Myelodysplasia (ISO)

thrombocytopenia (ISO)

Thrombocytopenic Purpura (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blood coagulation (IEA)

blood coagulation, intrinsic pathway (IEA)

megakaryocyte development (IEA)

positive regulation of platelet activation (IEA)

release of sequestered calcium ion into cytosol (IEA)

Cellular Component

glycoprotein Ib-IX-V complex (IEA,ISO)

membrane (IEA)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

platelet aggregation pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

GP9
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	52,000,620 - 52,013,570 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	52,000,758 - 52,001,291 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	114,366,247 - 114,367,885 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

GP9
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	129,054,845 - 129,062,406 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	129,060,779 - 129,062,406 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	128,779,622 - 128,781,249 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	130,262,335 - 130,263,939 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	130,262,342 - 130,263,945	NCBI
Celera	3	127,211,950 - 127,213,558 (+)	NCBI		Celera
Cytogenetic Map	3	q21.3	NCBI
HuRef	3	126,166,125 - 126,167,732 (+)	NCBI		HuRef
CHM1_1	3	128,743,075 - 128,744,683 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	131,799,713 - 131,807,274 (+)	NCBI		T2T-CHM13v2.0

Gp9
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	87,753,115 - 87,756,768 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	87,755,054 - 87,756,750 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	87,776,131 - 87,779,786 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	87,778,072 - 87,779,768 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	87,728,130 - 87,729,756 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	87,743,777 - 87,745,403 (+)	NCBI		MGSCv36	mm8
Celera	6	89,715,360 - 89,716,986 (+)	NCBI		Celera
Cytogenetic Map	6	D1	NCBI
cM Map	6	39.13	NCBI

Gp9
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	121,792,842 - 121,794,452 (+)	NCBI		GRCr8
mRatBN7.2	4	120,235,500 - 120,237,110 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	120,235,421 - 120,237,110 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	125,714,540 - 125,715,875 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	121,489,331 - 121,490,666 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	120,113,566 - 120,114,901 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	119,680,671 - 119,682,006 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	119,680,112 - 119,682,547 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	184,931,999 - 184,933,334 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	121,965,797 - 121,967,132 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	109,196,129 - 109,197,464 (+)	NCBI		Celera
Cytogenetic Map	4	q34	NCBI

Gp9
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955450	10,478,165 - 10,479,425 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955450	10,478,165 - 10,479,425 (-)	NCBI	ChiLan1.0	ChiLan1.0

GP9
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	126,993,599 - 126,997,569 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	126,998,316 - 127,002,292 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	126,118,762 - 126,122,732 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	133,479,202 - 133,480,843 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	133,480,173 - 133,480,706 (+)	Ensembl	panpan1.1		panPan2

GP9
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	3,027,790 - 3,029,496 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	3,064,497 - 3,066,213 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	3,048,622 - 3,050,338 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	3,048,699 - 3,049,232 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	2,768,165 - 2,769,881 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	3,090,922 - 3,092,638 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	3,055,430 - 3,057,146 (-)	NCBI		UU_Cfam_GSD_1.0

Gp9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404942	20,128,784 - 20,129,755 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936798	170,654 - 171,625 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GP9
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	71,560,012 - 71,562,774 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	71,558,768 - 71,565,134 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	79,213,436 - 79,213,825 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Gp9
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624781	7,579,824 - 7,581,516 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium		17
Low	2	3	7
Below cutoff	10		27

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_007985408	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007985409	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007985410	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_007985411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000018902 ⟹ ENSCSAP00000018332

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	22	52,000,758 - 52,001,291 (-)	Ensembl

RefSeq Acc Id:

XM_007985411 ⟹ XP_007983602

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	22	52,000,620 - 52,002,447 (-)	NCBI
Vero_WHO_p1.0	NW_023666041	114,366,247 - 114,367,885 (+)	NCBI

Sequence:

show sequence

CAGTCACAGCACTGGCGGCACAGTGGGACACCCTTCATAAACCGGGGTTGAGATGTGGTTCTGT
GCCCAAGGCGCGGGCCCCTGAGGGCCTCCAGCCTCTGGAAATAGGCCCCAGGGCTGCACTGGGG
GGATAAGCCAGGCTATTTTCATCACTTCCTTCCACCCGCTTCCGCAGGGGCCACCTCAGCTGCA
TCCCATAGAGTTGCCACCCAGACCTCAGCCAGGACCTTTCAGGCCACGCGGGAGTGCCCAACCA
AAGGCTTCACAGCTGCCCTCACCACCCTGCCTTCAACGGTGTCCAGAGAGGGTCAGCCAGGCCT
GGGTTGGGCACGCTGTACCTTCCCCAGTCACCAGCCTGTTTCCCGGAGGAGAAGGCTGAGACCC
GAGAAGGGAGCCAGCCTGTCCCATGCCTGCCTGGGAAGCCCTGTTCCTGCTCTGGGCCACAGCA
GAGGCCACCAAGGACTGCCCTATCCCATGCACCTGCCGCGCCCTGGAAACCATGGGGCTGTGGG
TGGACTGCAGGGGCCGCGGGCTCACGGCCCTGCCTGCCCTGCCAGCCCGCACCCGCCACCTCCT
GCTGGCCAACAACAGCCTTCAGTCCGTGCCCCCGGGAGCCTTCGACCACCTGCCCCAGCTGCAG
ACCCTCGATGTGACGCAGAACCCGTGGCACTGTGACTGCAGCCTCACCTATCTGCGCCTCTGGC
TGGAGGACCGCACACCTGAGGCCCTGCTGCAGGTCCGCTGCGCCAGCCCCAGCCTCGCTGCCCA
TGGCCCGCTGGGCCAGCTGACAGGCTACCAGCTGGGCAGCTGCGGCTGGCAGCTGCAGGCGTCC
TGGGTGCGCTCAGGGGTCTTGTGGGACGTGGCACTGGTCGCCGTGGCTGCGCTGGGCCTGGCTC
TTCTGGCTGGCCTGCTGTGTGCCACCACTGAGGCCCTGGATTGAGCCAGGCCCCCAGAACCCCT
GGTCCCAGGCCAGGGGGCCAGTCCCTGAGGCAGGTCCCCAGACTCCGCCAAGCCTGGTCAGCCC
AAACCACTAGAAGCCCAAAATAAACTGGCAGCTTGGCTGTTTTATATAAGCTCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007983602	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000018332
	ENSCSAP00000018332.1

RefSeq Acc Id:	XP_007983602 ⟸ XM_007985411
- UniProtKB:	A0A0D9SBU3 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000018332 ⟸ ENSCSAT00000018902

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000018812	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000018902.1	UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
InterPro	Cys-rich_flank_reg_C	UniProtKB/TrEMBL
	Leu-rich_rpt	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
	LRRNT	UniProtKB/TrEMBL
NCBI Gene	GP9	ENTREZGENE
PANTHER	GLYCOPROTEIN IB BETA	UniProtKB/TrEMBL
	PLATELET GLYCOPROTEIN IX	UniProtKB/TrEMBL
Pfam	LRR_8	UniProtKB/TrEMBL
	LRRNT	UniProtKB/TrEMBL
SMART	LRRCT	UniProtKB/TrEMBL
	LRRNT	UniProtKB/TrEMBL
Superfamily-SCOP	L domain-like	UniProtKB/TrEMBL
UniProt	A0A0D9SBU3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

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