SCT (secretin) - Rat Genome Database

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Gene: SCT (secretin) Chlorocebus sabaeus
Analyze
Symbol: SCT
Name: secretin
RGD ID: 18534965
Description: ENCODES a protein that exhibits digestive hormone activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); dentate gyrus development (ortholog); diet induced thermogenesis (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Beckwith-Wiedemann syndrome (ortholog); Chanarin-Dorfman syndrome (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11444,487 - 445,535 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1444,601 - 445,339 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603897,504,399 - 97,506,110 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SCT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11444,487 - 445,535 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1444,601 - 445,339 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603897,504,399 - 97,506,110 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SCT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811626,309 - 627,181 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11626,309 - 627,181 (-)EnsemblGRCh38hg38GRCh38
GRCh3711626,309 - 627,181 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611616,313 - 617,173 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411616,312 - 617,173NCBI
Celera11691,460 - 692,319 (-)NCBICelera
Cytogenetic Map11p15.5NCBI
HuRef11441,591 - 442,452 (-)NCBIHuRef
CHM1_111625,319 - 626,154 (-)NCBICHM1_1
T2T-CHM13v2.011674,921 - 675,793 (-)NCBIT2T-CHM13v2.0
Sct
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,858,243 - 140,859,082 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7140,858,243 - 140,859,046 (-)EnsemblGRCm39 Ensembl
GRCm387141,278,329 - 141,279,174 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,278,330 - 141,279,133 (-)EnsemblGRCm38mm10GRCm38
MGSCv377148,464,237 - 148,465,030 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367141,129,650 - 141,130,426 (-)NCBIMGSCv36mm8
Celera7141,072,071 - 141,072,883 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.59NCBI
Sct
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81205,812,435 - 205,813,246 (-)NCBIGRCr8
mRatBN7.21196,382,857 - 196,383,668 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,382,856 - 196,383,658 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1204,728,423 - 204,729,117 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01211,855,200 - 211,855,894 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01204,529,338 - 204,530,032 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01214,264,865 - 214,277,437 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,264,754 - 214,265,668 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,182,403 - 221,191,992 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,472,250 - 201,472,944 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11201,623,164 - 201,623,978 (-)NCBI
Celera1194,016,798 - 194,017,492 (-)NCBICelera
Cytogenetic Map1q41NCBI
Sct
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,433,969 - 11,434,574 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,433,857 - 11,434,662 (+)NCBIChiLan1.0ChiLan1.0
SCT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v293,004,772 - 3,006,739 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1112,221,004 - 2,222,552 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011632,073 - 634,296 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111661,461 - 662,008 (-)NCBIpanpan1.1PanPan1.1panPan2
SCT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha1825,367,827 - 25,368,884 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01826,303,408 - 26,304,465 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1826,303,525 - 26,304,498 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11825,812,919 - 25,814,007 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01825,457,869 - 25,458,979 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01826,070,329 - 26,071,383 (-)NCBIUU_Cfam_GSD_1.0
Sct
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947459,168 - 459,911 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936888459,247 - 459,911 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936888459,168 - 459,919 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2383,799 - 384,841 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12382,783 - 385,082 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22289,564 - 290,744 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sct
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476621,842,014 - 21,842,683 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476621,841,994 - 21,842,754 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
50 35 20 35 35 35 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007985567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000008889   ⟹   ENSCSAP00000007023
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1444,601 - 445,339 (-)Ensembl
RefSeq Acc Id: XM_007985567   ⟹   XP_007983758
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11444,487 - 445,535 (-)NCBI
Vero_WHO_p1.0NW_02366603897,504,399 - 97,506,110 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007983758 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007023
  ENSCSAP00000007023.1
RefSeq Acc Id: XP_007983758   ⟸   XM_007985567
- UniProtKB: A0A0D9REI4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000007023   ⟸   ENSCSAT00000008889


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010809 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008889.1 UniProtKB/TrEMBL
InterPro Glucagon_GIP_secretin_VIP UniProtKB/TrEMBL
  Prosecretin UniProtKB/TrEMBL
NCBI Gene SCT ENTREZGENE
PANTHER PTHR17378 UniProtKB/TrEMBL
  SECRETIN UniProtKB/TrEMBL
Pfam Hormone_2 UniProtKB/TrEMBL
PROSITE GLUCAGON UniProtKB/TrEMBL
SMART GLUCA UniProtKB/TrEMBL
UniProt A0A0D9REI4 ENTREZGENE, UniProtKB/TrEMBL