EMILIN2 (elastin microfibril interfacer 2) - Rat Genome Database

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Gene: EMILIN2 (elastin microfibril interfacer 2) Chlorocebus sabaeus
Analyze
Symbol: EMILIN2
Name: elastin microfibril interfacer 2
RGD ID: 18645190
Description: INVOLVED IN negative regulation of cell migration (ortholog); positive regulation of angiogenesis (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH chromosome 18p deletion syndrome (ortholog); facioscapulohumeral muscular dystrophy 2 (ortholog); genetic disease (ortholog); FOUND IN extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EMILIN-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11862,110,324 - 62,171,066 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1862,110,616 - 62,170,384 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605036,965,893 - 37,026,280 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
EMILIN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11862,110,324 - 62,171,066 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1862,110,616 - 62,170,384 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605036,965,893 - 37,026,280 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
EMILIN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38182,846,232 - 2,916,003 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl182,847,006 - 2,916,003 (+)EnsemblGRCh38hg38GRCh38
GRCh37182,847,004 - 2,916,001 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36182,837,028 - 2,904,090 (+)NCBINCBI36Build 36hg18NCBI36
Build 34182,837,027 - 2,904,088NCBI
Celera182,722,463 - 2,789,538 (+)NCBICelera
Cytogenetic Map18p11.32-p11.31NCBI
HuRef182,808,350 - 2,875,373 (+)NCBIHuRef
CHM1_1182,846,395 - 2,913,454 (+)NCBICHM1_1
T2T-CHM13v2.0183,001,875 - 3,071,504 (+)NCBIT2T-CHM13v2.0
Emilin2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391771,559,167 - 71,618,551 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1771,559,167 - 71,618,973 (-)EnsemblGRCm39 Ensembl
GRCm381771,252,172 - 71,311,556 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1771,252,172 - 71,311,978 (-)EnsemblGRCm38mm10GRCm38
MGSCv371771,601,516 - 71,660,305 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361771,154,355 - 71,216,323 (-)NCBIMGSCv36mm8
Celera1775,520,092 - 75,581,836 (-)NCBICelera
Cytogenetic Map17E1.3NCBI
cM Map1741.87NCBI
Emilin2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89118,607,312 - 118,667,087 (-)NCBIGRCr8
mRatBN7.29111,160,708 - 111,220,463 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9111,160,712 - 111,220,352 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.09119,594,049 - 119,653,675 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9119,594,629 - 119,653,255 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09119,047,568 - 119,106,639 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49110,458,062 - 110,488,722 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19110,668,124 - 110,751,827 (-)NCBI
Celera9108,289,680 - 108,349,263 (-)NCBICelera
Cytogenetic Map9q38NCBI
Emilin2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554027,508,159 - 7,519,977 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554027,507,674 - 7,519,978 (-)NCBIChiLan1.0ChiLan1.0
EMILIN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21735,533,333 - 35,599,301 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11821,225,935 - 21,291,535 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01811,368,328 - 11,435,808 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11813,678,090 - 13,743,075 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1813,678,772 - 13,743,346 (-)Ensemblpanpan1.1panPan2
EMILIN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1769,521,430 - 69,580,963 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha768,976,680 - 69,036,232 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0769,583,656 - 69,642,665 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl769,584,913 - 69,643,162 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1769,266,531 - 69,325,009 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0769,286,034 - 69,345,061 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0769,583,984 - 69,642,505 (+)NCBIUU_Cfam_GSD_1.0
Emilin2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494465,880,202 - 65,931,886 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366721,609,193 - 1,661,528 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366721,607,914 - 1,661,531 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EMILIN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6103,730,626 - 103,786,927 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16103,730,618 - 103,786,921 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2696,739,144 - 96,792,557 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Emilin2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477013,133,319 - 13,156,420 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 5
Low 36 15 40
Below cutoff 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007974520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000015700   ⟹   ENSCSAP00000013632
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1862,110,616 - 62,170,384 (+)Ensembl
RefSeq Acc Id: XM_007974520   ⟹   XP_007972711
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11862,110,324 - 62,171,066 (+)NCBI
Vero_WHO_p1.0NW_02366605036,965,893 - 37,026,280 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007972711 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000013632.1
Reference Protein Sequences
RefSeq Acc Id: XP_007972711   ⟸   XM_007974520
- UniProtKB: A0A0D9RYE3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000013632   ⟸   ENSCSAT00000015700


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000017605 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000015700.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.60 UniProtKB/TrEMBL
  2.60.120.40 UniProtKB/TrEMBL
InterPro C1q_dom UniProtKB/TrEMBL
  EMI_domain UniProtKB/TrEMBL
  Tumour_necrosis_fac-like_dom UniProtKB/TrEMBL
KEGG Report csab:103222697 UniProtKB/TrEMBL
NCBI Gene EMILIN2 ENTREZGENE
PANTHER EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER UniProtKB/TrEMBL
  EMILIN-2 UniProtKB/TrEMBL
Pfam C1q UniProtKB/TrEMBL
  EMI UniProtKB/TrEMBL
PROSITE C1Q UniProtKB/TrEMBL
  EMI UniProtKB/TrEMBL
SMART C1Q UniProtKB/TrEMBL
Superfamily-SCOP SSF49842 UniProtKB/TrEMBL
UniProt A0A0D9RYE3 ENTREZGENE, UniProtKB/TrEMBL