A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex.
blood coagulation, extrinsic pathway +
blood coagulation, fibrin clot formation +
blood coagulation, intrinsic pathway +
kinin cascade +
negative regulation of protein activation cascade +
positive regulation of protein activation cascade +