IL6R (interleukin 6 receptor) - Rat Genome Database

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Gene: IL6R (interleukin 6 receptor) Chlorocebus sabaeus
Analyze
Symbol: IL6R
Name: interleukin 6 receptor
RGD ID: 18768490
Description: ENCODES a protein that exhibits ciliary neurotrophic factor binding (inferred); ciliary neurotrophic factor receptor activity (inferred); cytokine receptor activity (inferred); INVOLVED IN developmental growth (ortholog); negative regulation of collagen biosynthetic process (ortholog); positive regulation of cell population proliferation (ortholog); PARTICIPATES IN interleukin-6 signaling pathway; ASSOCIATED WITH Acute-Phase Reaction (ortholog); Alzheimer's disease (ortholog); arrhythmogenic right ventricular cardiomyopathy (ortholog); FOUND IN extracellular space (ortholog); neuronal cell body membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: interleukin-6 receptor subunit alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1209,345,723 - 9,418,963 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl209,361,152 - 9,396,610 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660388,700,264 - 8,762,770 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 32 rows

  
Object Symbol
Species
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Reference
Notes
Source
Original Reference(s)
IL6RGreen MonkeyAcute-Phase Reaction  ISOIl6r (Rattus norvegicus)9068941mRNA:increased expression:liverRGDPMID:2174054 and REF_RGD_ID:729416
IL6RGreen MonkeyAlzheimer's disease  ISOIL6R (Homo sapiens)9068941protein:increased expression:cerebrospinal fluid and plasmaRGDPMID:12664314 and REF_RGD_ID:10402808
IL6RGreen MonkeyAlzheimer's disease no_associationISOIL6R (Homo sapiens)9068941DNA:SNPs:promoter:-208G>A (rs4845617) (human)RGDPMID:20197062 and REF_RGD_ID:10402810
IL6RGreen MonkeyAlzheimer's disease  ISOIL6R (Homo sapiens)9068941DNA:SNPs:promoter more ...RGDPMID:20197062 and REF_RGD_ID:10402810
IL6RGreen Monkeyarrhythmogenic right ventricular cardiomyopathy  ISOIL6R (Homo sapiens)9068941protein:increased expression:serumRGDPMID:21859801 and REF_RGD_ID:10402826
IL6RGreen Monkeyasthma  ISOIl6ra (Mus musculus)9068941 RGDPMID:17496315 more ...
IL6RGreen Monkeycongestive heart failure  ISOIl6r (Rattus norvegicus)9068941protein:increased expression:paraventricular hypothalamic nucleusRGDPMID:17095650 and REF_RGD_ID:1625433
IL6RGreen Monkeydepressive disorder  ISOIl6r (Rattus norvegicus)9068941mRNA:increased expression:colonRGDPMID:23589140 and REF_RGD_ID:10402829
IL6RGreen MonkeyExperimental Seizures  ISOIl6r (Rattus norvegicus)9068941mRNA:increased expression:hippocampusRGDPMID:12591161 and REF_RGD_ID:1625441
IL6RGreen MonkeyGraves' disease disease_progressionISOIL6R (Homo sapiens)9068941protein:increased expression:serum:RGDPMID:12818091 and REF_RGD_ID:7829750
IL6RGreen MonkeyHuntington's disease treatmentISOIL6R (Homo sapiens)9068941 RGDPMID:11860469 and REF_RGD_ID:10402809
IL6RGreen MonkeyHyperalgesia  ISOIl6r (Rattus norvegicus)9068941mRNA:increased expression:dorsal root ganglionRGDPMID:23953943 and REF_RGD_ID:10402830
IL6RGreen Monkeyhypertension severityISOIL6R (Homo sapiens)9068941Hypertension more ...RGDPMID:11778537 and REF_RGD_ID:1625432
IL6RGreen MonkeyInsulin Resistance  ISOIL6R (Homo sapiens)9068941protein:decreased expression:serumRGDPMID:14962155 and REF_RGD_ID:1625431
IL6RGreen MonkeyMetabolic Syndrome susceptibilityISOIL6R (Homo sapiens)9068941DNA:polymorphism: :p.D358ARGDPMID:16817825 and REF_RGD_ID:1625430
IL6RGreen Monkeymyocardial infarction  ISOIl6r (Rattus norvegicus)9068941 RGDPMID:12123772 and REF_RGD_ID:1625444
IL6RGreen MonkeyMyocardial Reperfusion Injury  ISOIL6R (Homo sapiens)9068941 RGDPMID:16056242 and REF_RGD_ID:1625435
IL6RGreen Monkeyobesity susceptibilityISOIL6R (Homo sapiens)9068941DNA:polymorphism: :p.D358ARGDPMID:16817825 and REF_RGD_ID:1625430
IL6RGreen Monkeyobesity  ISOIL6R (Homo sapiens)9068941DNA:SNP and haplotypes:promoter:-208G>A (rs4845617) (human)RGDPMID:17984249 and REF_RGD_ID:10402807
IL6RGreen Monkeyobesity  ISOIL6R (Homo sapiens)9068941protein:increased expression:serumRGDPMID:17434052 and REF_RGD_ID:1625429
1 to 20 of 32 rows
1 to 9 of 9 rows
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Original Reference(s)
IL6RGreen MonkeyCharcot-Marie-Tooth disease type 2  ISOIL6R (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth disease type 2ClinVarPMID:28492532 and PMID:29845577
IL6RGreen Monkeydyschromatosis symmetrica hereditaria  ISOIL6R (Homo sapiens)8554872ClinVar Annotator: match by term: Symmetrical dyschromatosis of extremitiesClinVarPMID:22974014 and PMID:28492532
IL6RGreen Monkeygastrointestinal stromal tumor  ISOIL6R (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
IL6RGreen MonkeyHyper-IgE Recurrent Infection Syndrome 5  ISOIL6R (Homo sapiens)8554872ClinVar Annotator: match by term: Hyper-IgE recurrent infection syndrome 5 and autosomal recessiveClinVarPMID:25741868 more ...
IL6RGreen Monkeyimmunodeficiency 42  ISOIL6R (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal recessive mendelian susceptibility to mycobacterial diseases due to complete RORgamma receptor deficiencyClinVarPMID:28492532
IL6RGreen MonkeyMHC class II deficiency  ISOIL6R (Homo sapiens)8554872ClinVar Annotator: match by term: MHC class II deficiencyClinVarPMID:28492532
IL6RGreen Monkeyparathyroid carcinoma  ISOIL6R (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
IL6RGreen Monkeysevere congenital neutropenia 3  ISOIL6R (Homo sapiens)8554872ClinVar Annotator: match by term: Kostmann syndromeClinVarPMID:17187068 and PMID:28492532
IL6RGreen Monkeysevere congenital neutropenia 5  ISOIL6R (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital neutropenia-myelofibrosis-nephromegaly syndromeClinVarPMID:28492532
1 to 9 of 9 rows
1 to 13 of 13 rows
Object Symbol
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Evidence
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Reference
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Source
Original Reference(s)
IL6RGreen Monkeyasthma  ISOIL6R (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:29902480
IL6RGreen MonkeyFever  ISOIl6ra (Mus musculus)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25429137
IL6RGreen MonkeyGraves' disease  ISOIL6R (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16372246
IL6RGreen MonkeyHashimoto Disease  ISOIL6R (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16372246
IL6RGreen MonkeyHeat Stroke  ISOIl6ra (Mus musculus)9068941CTD Direct Evidence: marker/mechanismCTDPMID:24039931
IL6RGreen Monkeylung non-small cell carcinoma  ISOIL6R (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:22552503
IL6RGreen Monkeymiddle cerebral artery infarction  ISOIl6ra (Mus musculus)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21940958
IL6RGreen Monkeyosteoporosis  ISOIL6R (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:15995586
IL6RGreen Monkeyrenal cell carcinoma  ISOIL6R (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:7834629
IL6RGreen MonkeyReperfusion Injury  ISOIl6ra (Mus musculus)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21940958
IL6RGreen Monkeyrheumatoid arthritis  ISOIL6R (Homo sapiens)9068941CTD more ...CTDPMID:16729287 and PMID:23143596
IL6RGreen Monkeyschizophrenia  ISOIL6R (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:8067274
IL6RGreen MonkeyStomach Neoplasms  ISOIL6R (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16367923
1 to 13 of 13 rows
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Original Reference(s)
IL6RGreen MonkeyHyper-IgE Recurrent Infection Syndrome 5  ISOIL6R (Homo sapiens)7240710 OMIM 


Biological Process
1 to 20 of 28 rows

  
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Original Reference(s)
IL6RGreen Monkeycell surface receptor signaling pathway involved_inIEAARBA:ARBA00029053150520179 UniProtGO_REF:0000117
IL6RGreen Monkeycell surface receptor signaling pathway via STAT involved_inIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyciliary neurotrophic factor-mediated signaling pathway involved_inIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeycytokine-mediated signaling pathway involved_inIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeycytokine-mediated signaling pathway involved_inIEAPANTHER:PTN007726888150520179 TreeGrafterGO_REF:0000118
IL6RGreen Monkeydevelopmental growth  ISOIl6r (Rattus norvegicus)9068941 RGDPMID:23855552 and REF_RGD_ID:10402824
IL6RGreen Monkeyendocrine pancreas development involved_inIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyimmunoglobulin mediated immune response involved_inIEAPANTHER:PTN007726888150520179 TreeGrafterGO_REF:0000118
IL6RGreen Monkeyinterleukin-6-mediated signaling pathway involved_inIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyinterleukin-6-mediated signaling pathway acts_upstream_of_or_withinIEAUniProtKB:P22272 and ensembl:ENSMUSP00000029559150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeynegative regulation of collagen biosynthetic process involved_inISOIL6R (Homo sapiens)9068941 PMID:12419823BHF-UCLPMID:12419823
IL6RGreen Monkeypositive regulation of cell population proliferation  ISOIl6r (Rattus norvegicus)9068941 RGDPMID:19961020 and REF_RGD_ID:5128678
IL6RGreen Monkeypositive regulation of cell population proliferation involved_inIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeypositive regulation of chemokine production involved_inIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeypositive regulation of glomerular mesangial cell proliferation involved_inIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeypositive regulation of interleukin-6 production involved_inIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeypositive regulation of MAPK cascade involved_inISOIL6R (Homo sapiens)9068941 PMID:12419823BHF-UCLPMID:12419823
IL6RGreen Monkeypositive regulation of platelet aggregation acts_upstream_ofISOIL6R (Homo sapiens)9068941 PMID:31145836ARUK-UCLPMID:31145836
IL6RGreen Monkeypositive regulation of smooth muscle cell proliferation involved_inIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyresponse to cAMP  ISOIl6r (Rattus norvegicus)9068941 RGDPMID:7814800 and REF_RGD_ID:1625445
1 to 20 of 28 rows

Cellular Component
1 to 13 of 13 rows

  
Object Symbol
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Evidence
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Reference
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Original Reference(s)
IL6RGreen Monkeyapical plasma membrane located_inIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyciliary neurotrophic factor receptor complex part_ofIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyexternal side of plasma membrane located_inIEAPANTHER:PTN007726888150520179 TreeGrafterGO_REF:0000118
IL6RGreen Monkeyextracellular region located_inIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyextracellular space located_inISOIL6R (Homo sapiens)9068941 PMID:12419823 more ...BHF-UCLPMID:12419823 more ...
IL6RGreen Monkeyextracellular space is_active_inISOIL6R (Homo sapiens)9068941 PMID:21990364UniProtPMID:21990364
IL6RGreen Monkeyextracellular space  ISOIl6r (Rattus norvegicus)9068941 RGDPMID:11448096 and REF_RGD_ID:1625446
IL6RGreen Monkeyinterleukin-6 receptor complex part_ofIEAUniProtKB:P08887 more ...150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeymembrane located_inIEAInterPro:IPR003530150520179 InterProGO_REF:0000002
IL6RGreen Monkeymembrane located_inIEAUniProtKB-SubCell:SL-0162150520179 UniProtGO_REF:0000044
IL6RGreen Monkeymembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
IL6RGreen Monkeyneuronal cell body membrane  ISOIl6r (Rattus norvegicus)9068941 RGDPMID:8921254 and REF_RGD_ID:5686896
IL6RGreen Monkeyplasma membrane is_active_inISOIL6R (Homo sapiens)9068941 PMID:12829785UniProtPMID:12829785
1 to 13 of 13 rows

Molecular Function
1 to 16 of 16 rows

  
Object Symbol
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Reference
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Original Reference(s)
IL6RGreen Monkeyciliary neurotrophic factor binding enablesIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyciliary neurotrophic factor receptor activity contributes_toIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeycytokine receptor activity enablesIEAInterPro:IPR003530150520179 InterProGO_REF:0000002
IL6RGreen Monkeycytokine receptor activity enablesIEAPANTHER:PTN007726888150520179 TreeGrafterGO_REF:0000118
IL6RGreen Monkeyenzyme binding enablesIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyinterleukin-6 binding enablesIEAUniProtKB:P08887 more ...150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyinterleukin-6 receptor activity enablesIEAUniProtKB:P22272 and ensembl:ENSMUSP00000029559150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyinterleukin-6 receptor activity contributes_toIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyinterleukin-6 receptor binding contributes_toIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
IL6RGreen Monkeyprotein binding enablesISOUniProtKB:P785369068941 PMID:16034137BHF-UCLPMID:16034137
IL6RGreen Monkeyprotein binding enablesISOUniProtKB:P05231 and UniProtKB:Q2HRC79068941 PMID:11238858IntActPMID:11238858
IL6RGreen Monkeyprotein binding enablesISOUniProtKB:P05231 and UniProtKB:Q926739068941 PMID:28265003IntActPMID:28265003
IL6RGreen Monkeyprotein binding enablesISOUniProtKB:O002339068941 PMID:25009770IntActPMID:25009770
IL6RGreen Monkeyprotein binding enablesISOUniProtKB:P052319068941 PMID:12829785 more ...IntActPMID:12829785 more ...
IL6RGreen Monkeyprotein binding enablesISOUniProtKB:Q96EQ09068941 PMID:32296183IntActPMID:32296183
IL6RGreen Monkeyprotein homodimerization activity enablesIEAUniProtKB:P08887 and ensembl:ENSP00000357470150520179 EnsemblGO_REF:0000107
1 to 16 of 16 rows

RGD Manual Annotations


  
Object Symbol
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Qualifier
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Reference
Notes
Source
Original Reference(s)
IL6RGreen Monkeyinterleukin-6 signaling pathway   ISOIL6R (Homo sapiens)9068941 RGDPMID:21881215 more ...

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
IL6RGreen Monkeyinterleukin-6 signaling pathway   ISOIL6R (Homo sapiens)9068941 PIDPID:200146
PMID:22301074   PMID:30032202  



IL6R
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1209,345,723 - 9,418,963 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl209,361,152 - 9,396,610 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660388,700,264 - 8,762,770 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
IL6R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381154,405,343 - 154,469,450 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1154,405,193 - 154,469,450 (+)EnsemblGRCh38hg38GRCh38
GRCh371154,377,819 - 154,441,926 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361152,644,293 - 152,706,812 (+)NCBINCBI36Build 36hg18NCBI36
Build 341151,190,741 - 151,253,261NCBI
Celera1127,449,298 - 127,511,851 (+)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1125,740,964 - 125,805,584 (+)NCBIHuRef
CHM1_11155,774,020 - 155,838,256 (+)NCBICHM1_1
T2T-CHM13v2.01153,542,427 - 153,606,601 (+)NCBIT2T-CHM13v2.0
Il6ra
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39389,776,631 - 89,820,503 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl389,771,366 - 89,820,503 (-)EnsemblGRCm39 Ensembl
GRCm38389,869,324 - 89,913,196 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl389,864,059 - 89,913,196 (-)EnsemblGRCm38mm10GRCm38
MGSCv37389,673,246 - 89,717,084 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36389,962,736 - 89,998,969 (-)NCBIMGSCv36mm8
Celera389,906,161 - 89,949,620 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.19NCBI
Il6r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,582,020 - 177,646,705 (-)NCBIGRCr8
mRatBN7.22175,289,157 - 175,347,719 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,298,686 - 175,347,536 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2182,447,296 - 182,496,140 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02180,469,671 - 180,518,517 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02175,070,810 - 175,119,703 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,196,180 - 189,255,987 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,205,701 - 189,254,628 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02208,619,391 - 208,679,233 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42182,078,049 - 182,128,135 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12182,028,156 - 182,078,238 (-)NCBI
Celera2169,240,233 - 169,289,575 (-)NCBICelera
Cytogenetic Map2q34NCBI
Il6r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955545950,765 - 981,762 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955545932,814 - 979,359 (+)NCBIChiLan1.0ChiLan1.0
IL6R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2195,364,609 - 95,427,592 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1195,099,912 - 95,162,870 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01129,761,914 - 129,824,386 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,374,078 - 133,433,089 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1133,374,078 - 133,433,089 (+)Ensemblpanpan1.1panPan2
IL6R
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1742,877,731 - 42,920,149 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl742,880,885 - 42,920,090 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha742,368,082 - 42,410,484 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0742,747,387 - 42,789,817 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl742,747,374 - 42,790,122 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1742,526,574 - 42,569,177 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0742,580,411 - 42,622,783 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0742,864,074 - 42,906,503 (-)NCBIUU_Cfam_GSD_1.0
Il6r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505825,027,301 - 25,051,502 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365804,057,771 - 4,081,885 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365804,055,438 - 4,081,876 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL6R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl495,322,433 - 95,381,282 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1495,322,426 - 95,381,393 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24104,202,230 - 104,250,108 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Il6r
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248852,910,112 - 2,946,886 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248852,910,367 - 2,946,916 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in IL6R
2159 total Variants



ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20



Ensembl Acc Id: ENSCSAT00000016584   ⟹   ENSCSAP00000016089
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl209,361,152 - 9,396,610 (-)Ensembl
RefSeq Acc Id: XM_007976966   ⟹   XP_007975157
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1209,357,052 - 9,418,948 (-)NCBI
Vero_WHO_p1.0NW_0236660388,700,264 - 8,762,770 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037997867   ⟹   XP_037853795
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660388,700,264 - 8,762,770 (-)NCBI
Protein RefSeqs XP_007975157 (Get FASTA)   NCBI Sequence Viewer  
  XP_037853795 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000016089
  ENSCSAP00000016089.1
RefSeq Acc Id: XP_007975157   ⟸   XM_007976966
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S5F0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000016089   ⟸   ENSCSAT00000016584
RefSeq Acc Id: XP_037853795   ⟸   XM_037997867
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S5F0 (UniProtKB/TrEMBL)



1 to 27 of 27 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCSAG00000001948 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000016584.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Hematopoietin_rcpt_L_F3_CS UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
  TypeI_recpt_CBD UniProtKB/TrEMBL
NCBI Gene IL6R ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  CYTOKINE RECEPTOR COMMON SUBUNIT BETA UniProtKB/TrEMBL
Pfam IL6Ra-bind UniProtKB/TrEMBL
  PF00047 UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  HEMATOPO_REC_L_F3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
UniProt A0A0D9S5F0 ENTREZGENE, UniProtKB/TrEMBL
1 to 27 of 27 rows