NBEAL2 (neurobeachin like 2) - Rat Genome Database

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Gene: NBEAL2 (neurobeachin like 2) Chlorocebus sabaeus
Analyze
Symbol: NBEAL2
Name: neurobeachin like 2
RGD ID: 18596987
Description: ENCODES a protein that exhibits protein kinase binding (inferred); INVOLVED IN blood coagulation (ortholog); megakaryocyte development (ortholog); platelet alpha granule organization (ortholog); ASSOCIATED WITH genetic disease (ortholog); gray platelet syndrome (ortholog); hemorrhagic disease (ortholog); FOUND IN cytosol (inferred); endoplasmic reticulum (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neurobeachin-like protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,385,109 - 8,414,553 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl228,385,229 - 8,414,655 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041158,734,654 - 158,764,072 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NBEAL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,385,109 - 8,414,553 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl228,385,229 - 8,414,655 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041158,734,654 - 158,764,072 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
NBEAL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38346,979,666 - 47,009,701 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl346,979,666 - 47,009,704 (+)EnsemblGRCh38hg38GRCh38
GRCh37347,021,156 - 47,051,191 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,996,177 - 47,026,197 (+)NCBINCBI36Build 36hg18NCBI36
Celera346,959,687 - 46,989,710 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef347,064,280 - 47,094,298 (+)NCBIHuRef
CHM1_1346,971,583 - 47,001,579 (+)NCBICHM1_1
T2T-CHM13v2.0346,996,032 - 47,026,064 (+)NCBIT2T-CHM13v2.0
Nbeal2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,453,857 - 110,483,229 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9110,453,857 - 110,483,229 (-)EnsemblGRCm39 Ensembl
GRCm389110,624,789 - 110,654,161 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,624,789 - 110,654,161 (-)EnsemblGRCm38mm10GRCm38
MGSCv379110,527,293 - 110,556,665 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369110,469,609 - 110,498,977 (-)NCBIMGSCv36mm8
Celera9110,354,722 - 110,384,193 (-)NCBICelera
Cytogenetic Map9F2NCBI
cM Map960.27NCBI
Nbeal2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88119,481,608 - 119,511,997 (-)NCBIGRCr8
mRatBN7.28110,603,220 - 110,633,612 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8110,599,389 - 110,633,707 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.08118,893,987 - 118,924,390 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8118,893,995 - 118,926,613 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,234,959 - 118,265,227 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,005,741 - 115,034,787 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18115,025,276 - 115,055,017 (-)NCBI
Celera8109,887,398 - 109,917,800 (-)NCBICelera
Cytogenetic Map8q32NCBI
Nbeal2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542025,184,198 - 25,205,442 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542025,184,574 - 25,204,870 (-)NCBIChiLan1.0ChiLan1.0
NBEAL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2246,935,998 - 46,966,045 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1346,940,771 - 46,970,814 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0346,879,867 - 46,909,901 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1347,991,098 - 48,011,147 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl347,987,142 - 48,010,766 (+)Ensemblpanpan1.1panPan2
NBEAL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12041,806,903 - 41,836,286 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2041,803,702 - 41,827,587 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2041,723,466 - 41,752,507 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02042,290,044 - 42,319,069 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2042,290,104 - 42,318,880 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12041,531,736 - 41,560,747 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02041,932,687 - 41,961,726 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02042,213,648 - 42,242,687 (-)NCBIUU_Cfam_GSD_1.0
Nbeal2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118201,209,337 - 201,240,015 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936596758,495 - 789,168 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936596758,495 - 789,252 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NBEAL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1329,855,182 - 29,878,286 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11329,847,406 - 29,881,904 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21333,122,350 - 33,133,673 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Nbeal2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473074,284,240 - 74,310,201 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473074,283,938 - 74,310,340 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 16 13 16
Low 20 7 44
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007984003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007984004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007984005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007984006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007984007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007984008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007984009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_007984010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038004031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038004032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038004033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038004034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038004035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038004036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038004037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038004039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCSAT00000014236   ⟹   ENSCSAP00000012214
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl228,385,229 - 8,414,655 (+)Ensembl
RefSeq Acc Id: XM_007984003   ⟹   XP_007982194
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1228,385,109 - 8,414,553 (+)NCBI
Vero_WHO_p1.0NW_023666041158,734,654 - 158,764,072 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007984006   ⟹   XP_007982197
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1228,385,110 - 8,414,553 (+)NCBI
Vero_WHO_p1.0NW_023666041158,734,654 - 158,764,071 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007984008   ⟹   XP_007982199
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1228,389,122 - 8,414,553 (+)NCBI
Vero_WHO_p1.0NW_023666041158,734,654 - 158,761,350 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038004031   ⟹   XP_037859959
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666041158,734,654 - 158,761,352 (-)NCBI
RefSeq Acc Id: XM_038004032   ⟹   XP_037859960
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666041158,734,654 - 158,764,071 (-)NCBI
RefSeq Acc Id: XM_038004033   ⟹   XP_037859961
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666041158,734,654 - 158,764,072 (-)NCBI
RefSeq Acc Id: XM_038004034   ⟹   XP_037859962
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666041158,734,654 - 158,764,071 (-)NCBI
RefSeq Acc Id: XM_038004035   ⟹   XP_037859963
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666041158,734,654 - 158,764,071 (-)NCBI
RefSeq Acc Id: XM_038004036   ⟹   XP_037859964
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666041158,734,654 - 158,764,071 (-)NCBI
RefSeq Acc Id: XM_038004037   ⟹   XP_037859965
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666041158,734,654 - 158,764,071 (-)NCBI
RefSeq Acc Id: XM_038004039   ⟹   XP_037859967
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_023666041158,734,654 - 158,764,070 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_007982194   ⟸   XM_007984003
- Peptide Label: isoform X1
- UniProtKB: A0A0D9RUC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007982197   ⟸   XM_007984006
- Peptide Label: isoform X6
- UniProtKB: A0A0D9RUC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007982199   ⟸   XM_007984008
- Peptide Label: isoform X10
- UniProtKB: A0A0D9RUC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000012214   ⟸   ENSCSAT00000014236
RefSeq Acc Id: XP_037859961   ⟸   XM_038004033
- Peptide Label: isoform X4
- UniProtKB: A0A0D9RUC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037859964   ⟸   XM_038004036
- Peptide Label: isoform X8
- UniProtKB: A0A0D9RUC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037859963   ⟸   XM_038004035
- Peptide Label: isoform X7
- UniProtKB: A0A0D9RUC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037859960   ⟸   XM_038004032
- Peptide Label: isoform X3
- UniProtKB: A0A0D9RUC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037859965   ⟸   XM_038004037
- Peptide Label: isoform X9
- UniProtKB: A0A0D9RUC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037859962   ⟸   XM_038004034
- Peptide Label: isoform X5
- UniProtKB: A0A0D9RUC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037859967   ⟸   XM_038004039
- Peptide Label: isoform X11
- UniProtKB: A0A0D9RUC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037859959   ⟸   XM_038004031
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RUC5 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000016142 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000014236.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1540.10 UniProtKB/TrEMBL
  1.25.10.10 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  BEACH_dom UniProtKB/TrEMBL
  BEACH_dom_sf UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  DUF4704 UniProtKB/TrEMBL
  NBCH_WD40 UniProtKB/TrEMBL
  Neurobeachin_a-sol UniProtKB/TrEMBL
  PH-BEACH_dom UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene NBEAL2 ENTREZGENE
PANTHER BEIGE/BEACH-RELATED UniProtKB/TrEMBL
  PTHR13743:SF111 UniProtKB/TrEMBL
Pfam Beach UniProtKB/TrEMBL
  DUF4704 UniProtKB/TrEMBL
  DUF4800 UniProtKB/TrEMBL
  NBCH_WD40 UniProtKB/TrEMBL
  Neurobeachin UniProtKB/TrEMBL
  PH_BEACH UniProtKB/TrEMBL
PROSITE BEACH UniProtKB/TrEMBL
  PH_BEACH UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART Beach UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
  SSF50978 UniProtKB/TrEMBL
  SSF81837 UniProtKB/TrEMBL
UniProt A0A0D9RUC5 ENTREZGENE, UniProtKB/TrEMBL