GATA1 (GATA binding protein 1) - Rat Genome Database

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Gene: GATA1 (GATA binding protein 1) Chlorocebus sabaeus
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Symbol: GATA1
Name: GATA binding protein 1
RGD ID: 18787778
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN animal organ regeneration (ortholog); bone mineralization (ortholog); cell development (ortholog); ASSOCIATED WITH acute megakaryocytic leukemia (ortholog); acute myeloid leukemia (ortholog); Altitude Sickness (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); protein-DNA complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: erythroid transcription factor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X45,912,638 - 45,920,415 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX45,917,231 - 45,920,268 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607611,392,674 - 11,400,428 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anatomical structure morphogenesis  (IEA)
animal organ regeneration  (ISO)
basophil differentiation  (IEA)
bone mineralization  (IEA,ISO)
cell development  (IEA,ISO)
cell differentiation  (IEA)
cell fate commitment  (IEA)
cell population proliferation  (IEA,ISO)
cell-cell signaling  (IEA,ISO)
cellular response to cAMP  (ISO)
cellular response to follicle-stimulating hormone stimulus  (ISO)
cellular response to lipopolysaccharide  (ISO)
dendritic cell differentiation  (IEA,ISO)
embryonic hemopoiesis  (IEA,ISO)
eosinophil differentiation  (IEA)
eosinophil fate commitment  (IEA)
erythrocyte development  (IEA)
erythrocyte differentiation  (IEA,ISO)
homeostasis of number of cells within a tissue  (IEA,ISO)
in utero embryonic development  (IEA,ISO)
male gonad development  (IEA)
megakaryocyte differentiation  (IEA,ISO)
myeloid cell apoptotic process  (IEA,ISO)
myeloid cell differentiation  (IEA,ISO)
negative regulation of apoptotic process  (IEA)
negative regulation of bone mineralization  (IEA,ISO)
negative regulation of cell population proliferation  (IEA,ISO)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (IEA)
negative regulation of myeloid cell apoptotic process  (IEA,ISO)
negative regulation of transcription by RNA polymerase II  (IEA,ISO)
osteoblast proliferation  (IEA,ISO)
platelet aggregation  (IEA)
platelet formation  (IEA,ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of erythrocyte differentiation  (IEA)
positive regulation of mast cell degranulation  (ISO)
positive regulation of osteoblast proliferation  (IEA,ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
primitive erythrocyte differentiation  (IEA,ISO)
regulation of definitive erythrocyte differentiation  (IEA)
regulation of glycoprotein biosynthetic process  (IEA)
regulation of primitive erythrocyte differentiation  (IEA,ISO)
regulation of transcription by RNA polymerase II  (IEA)
Sertoli cell development  (ISO)
system development  (IEA)
transcription by RNA polymerase II  (IEA,ISO)

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GATA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X45,912,638 - 45,920,415 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX45,917,231 - 45,920,268 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607611,392,674 - 11,400,428 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
GATA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X48,786,590 - 48,794,311 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX48,786,540 - 48,794,311 (+)EnsemblGRCh38hg38GRCh38
GRCh37X48,644,998 - 48,652,718 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,529,906 - 48,537,662 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X48,401,209 - 48,408,964NCBI
CeleraX53,010,810 - 53,018,547 (-)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX46,304,230 - 46,311,086 (+)NCBIHuRef
CHM1_1X48,676,125 - 48,683,862 (+)NCBICHM1_1
T2T-CHM13v2.0X48,197,083 - 48,204,804 (+)NCBIT2T-CHM13v2.0
Gata1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,825,504 - 7,842,844 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,825,499 - 7,844,310 (-)EnsemblGRCm39 Ensembl
GRCm38X7,959,260 - 7,976,663 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX7,959,260 - 7,978,071 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X7,536,386 - 7,544,941 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X7,116,219 - 7,124,774 (-)NCBIMGSCv36mm8
CeleraX3,501,753 - 3,509,992 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.59NCBI
Gata1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X17,193,291 - 17,209,462 (+)NCBIGRCr8
mRatBN7.2X14,529,706 - 14,537,530 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,529,702 - 14,537,530 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX19,343,293 - 19,351,113 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X20,732,001 - 20,739,823 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X16,997,169 - 17,004,991 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X15,273,937 - 15,281,759 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,378,789 - 15,382,066 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,273,933 - 15,281,759 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,054,178 - 16,062,000 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,564,259 - 26,572,081 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X26,617,727 - 26,625,550 (+)NCBI
CeleraX14,614,331 - 14,622,295 (+)NCBICelera
Cytogenetic MapXq12NCBI
Gata1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543334,061 - 342,061 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955543334,581 - 342,042 (+)NCBIChiLan1.0ChiLan1.0
GATA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X50,280,196 - 50,283,660 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X50,283,568 - 50,287,032 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X41,088,724 - 41,092,190 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X48,945,394 - 48,953,126 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX48,945,394 - 48,953,126 (+)Ensemblpanpan1.1panPan2
GATA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X41,991,321 - 41,998,319 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX41,971,582 - 41,998,303 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,366,765 - 16,373,724 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X42,127,527 - 42,134,488 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX42,127,523 - 42,134,481 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X42,113,779 - 42,120,737 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X42,102,035 - 42,108,995 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X42,196,190 - 42,203,150 (+)NCBIUU_Cfam_GSD_1.0
Gata1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,488,565 - 34,510,496 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936721742,862 - 750,768 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936721742,862 - 750,843 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GATA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX42,898,442 - 42,905,976 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X42,898,431 - 42,905,939 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X47,745,326 - 47,752,876 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Gata1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624893595,967 - 602,979 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624893595,948 - 602,980 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
16 13 20 20 20 16 13

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007991602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000011294   ⟹   ENSCSAP00000009373
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 EnsemblX45,917,231 - 45,920,268 (+)Ensembl
RefSeq Acc Id: XM_007991602   ⟹   XP_007989793
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1X45,912,638 - 45,920,415 (+)NCBI
Vero_WHO_p1.0NW_02366607611,392,674 - 11,400,428 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007989793 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000009373
  ENSCSAP00000009373.1
RefSeq Acc Id: XP_007989793   ⟸   XM_007991602
- UniProtKB: A0A0D9RL84 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000009373   ⟸   ENSCSAT00000011294


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000013203 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000011294.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.50.10 UniProtKB/TrEMBL
InterPro Transcription_factor_GATA UniProtKB/TrEMBL
  Znf_GATA UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/TrEMBL
NCBI Gene GATA1 ENTREZGENE
PANTHER PTHR10071 UniProtKB/TrEMBL
  PTHR10071:SF190 UniProtKB/TrEMBL
Pfam GATA UniProtKB/TrEMBL
PRINTS GATAZNFINGER UniProtKB/TrEMBL
PROSITE GATA_ZN_FINGER_1 UniProtKB/TrEMBL
  GATA_ZN_FINGER_2 UniProtKB/TrEMBL
SMART ZnF_GATA UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt A0A0D9RL84 ENTREZGENE, UniProtKB/TrEMBL