TMX1 (thioredoxin related transmembrane protein 1) - Rat Genome Database

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Gene: TMX1 (thioredoxin related transmembrane protein 1) Chlorocebus sabaeus
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Symbol: TMX1
Name: thioredoxin related transmembrane protein 1
RGD ID: 18481372
Description: ENCODES a protein that exhibits disulfide oxidoreductase activity (inferred); enzyme inhibitor activity (inferred); protein disulfide isomerase activity (inferred); INVOLVED IN negative regulation of platelet aggregation (inferred); negative regulation of triglyceride biosynthetic process (inferred); positive regulation of ERAD pathway (inferred); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); mitochondria-associated endoplasmic reticulum membrane contact site (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: thioredoxin-related transmembrane protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12428,334,017 - 28,350,571 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2428,333,357 - 28,352,457 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605316,656,245 - 16,672,417 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
TMX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12428,334,017 - 28,350,571 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2428,333,357 - 28,352,457 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605316,656,245 - 16,672,417 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TMX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381451,240,247 - 51,257,655 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1451,240,162 - 51,257,655 (+)EnsemblGRCh38hg38GRCh38
GRCh371451,706,965 - 51,724,373 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361450,776,636 - 50,794,123 (+)NCBINCBI36Build 36hg18NCBI36
Build 341450,776,685 - 50,792,512NCBI
Celera1431,573,863 - 31,591,352 (+)NCBICelera
Cytogenetic Map14q22.1NCBI
HuRef1431,866,596 - 31,884,390 (+)NCBIHuRef
CHM1_11451,645,399 - 51,662,884 (+)NCBICHM1_1
T2T-CHM13v2.01445,446,717 - 45,464,426 (+)NCBIT2T-CHM13v2.0
Tmx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391270,499,928 - 70,514,398 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1270,499,869 - 70,514,814 (+)EnsemblGRCm39 Ensembl
GRCm381270,453,154 - 70,467,624 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1270,453,095 - 70,468,040 (+)EnsemblGRCm38mm10GRCm38
MGSCv371271,554,141 - 71,568,611 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361271,371,759 - 71,386,229 (+)NCBIMGSCv36mm8
Celera1271,558,987 - 71,573,471 (+)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1229.13NCBI
Tmx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8694,696,699 - 94,707,751 (+)NCBIGRCr8
mRatBN7.2688,960,691 - 88,971,744 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl688,960,695 - 88,971,301 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx689,352,744 - 89,363,806 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0689,652,189 - 89,663,251 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0689,091,717 - 89,102,779 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0692,864,123 - 92,875,141 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl692,864,123 - 92,874,204 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06102,311,253 - 102,322,281 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4692,562,592 - 92,572,638 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1692,566,047 - 92,576,094 (+)NCBI
Celera687,447,253 - 87,457,339 (+)NCBICelera
Cytogenetic Map6q24NCBI
Tmx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540911,710,646 - 11,722,342 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540911,708,867 - 11,722,205 (-)NCBIChiLan1.0ChiLan1.0
TMX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21552,378,563 - 52,394,539 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11451,595,079 - 51,612,555 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01431,844,418 - 31,861,911 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11450,129,565 - 50,146,148 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1450,129,568 - 50,147,057 (+)Ensemblpanpan1.1panPan2
TMX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1827,541,407 - 27,556,058 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl827,541,460 - 27,554,681 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha827,294,348 - 27,309,006 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0827,720,393 - 27,735,066 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl827,720,419 - 27,735,066 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1827,375,197 - 27,389,859 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0827,449,389 - 27,464,067 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0827,796,517 - 27,811,194 (+)NCBIUU_Cfam_GSD_1.0
Tmx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864059,744,345 - 59,759,804 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649514,431,137 - 14,447,476 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649514,432,971 - 14,447,380 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1180,933,859 - 180,951,341 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11180,933,678 - 180,950,826 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21201,220,189 - 201,235,370 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Tmx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473117,718,868 - 17,730,586 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473117,713,812 - 17,730,521 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007986670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000013183   ⟹   ENSCSAP00000011191
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2428,333,357 - 28,352,457 (+)Ensembl
RefSeq Acc Id: XM_007986670   ⟹   XP_007984861
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12428,334,017 - 28,350,571 (+)NCBI
Vero_WHO_p1.0NW_02366605316,656,245 - 16,672,417 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007984861 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000011191
  ENSCSAP00000011191.1
RefSeq Acc Id: XP_007984861   ⟸   XM_007986670
- UniProtKB: A0A0D9RRF2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000011191   ⟸   ENSCSAT00000013183


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000015090 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000013183.1 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro Thioredoxin-like_sf UniProtKB/TrEMBL
  Thioredoxin_CS UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/TrEMBL
  TMX_domain-containing UniProtKB/TrEMBL
KEGG Report csab:103228972 UniProtKB/TrEMBL
NCBI Gene TMX1 ENTREZGENE
PANTHER DUMPY: SHORTER THAN WILD-TYPE UniProtKB/TrEMBL
  THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 1 UniProtKB/TrEMBL
Pfam Thioredoxin UniProtKB/TrEMBL
PROSITE THIOREDOXIN_1 UniProtKB/TrEMBL
  THIOREDOXIN_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
UniProt A0A0D9RRF2 ENTREZGENE, UniProtKB/TrEMBL