SYTL2 (synaptotagmin like 2) - Rat Genome Database

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Gene: SYTL2 (synaptotagmin like 2) Chlorocebus sabaeus
Analyze
Symbol: SYTL2
Name: synaptotagmin like 2
RGD ID: 18680381
Description: ENCODES a protein that exhibits phosphatase binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN positive regulation of mucus secretion (ortholog); protein localization to plasma membrane (ortholog); vesicle docking involved in exocytosis (ortholog); ASSOCIATED WITH angioedema (ortholog); COVID-19 (ortholog); exudative vitreoretinopathy 1 (ortholog); FOUND IN cytoplasm (ortholog); melanosome (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: synaptotagmin-like protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1176,937,076 - 77,061,895 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604348,660,500 - 48,785,835 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SYTL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1176,937,076 - 77,061,895 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604348,660,500 - 48,785,835 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
SYTL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381185,694,229 - 85,854,870 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1185,694,224 - 85,811,159 (-)EnsemblGRCh38hg38GRCh38
GRCh371185,405,272 - 85,565,913 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361185,082,912 - 85,146,692 (-)NCBINCBI36Build 36hg18NCBI36
Build 341185,082,914 - 85,107,859NCBI
Celera1182,714,568 - 82,831,481 (-)NCBICelera
Cytogenetic Map11q14.1NCBI
HuRef1181,702,610 - 81,819,526 (-)NCBIHuRef
CHM1_11185,290,075 - 85,406,976 (-)NCBICHM1_1
T2T-CHM13v2.01185,630,917 - 85,791,555 (-)NCBIT2T-CHM13v2.0
Sytl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39789,951,421 - 90,059,927 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl789,951,460 - 90,059,927 (+)EnsemblGRCm39 Ensembl
GRCm38790,302,211 - 90,410,719 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl790,302,252 - 90,410,719 (+)EnsemblGRCm38mm10GRCm38
MGSCv37797,497,209 - 97,558,949 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36790,223,891 - 90,285,897 (+)NCBIMGSCv36mm8
Celera787,675,751 - 87,737,560 (+)NCBICelera
Cytogenetic Map7E1NCBI
cM Map750.54NCBI
Sytl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81153,685,403 - 153,791,758 (+)NCBIGRCr8
mRatBN7.21144,272,870 - 144,379,310 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1144,273,360 - 144,379,222 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1152,196,100 - 152,302,039 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01159,372,674 - 159,480,256 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01152,246,593 - 152,354,171 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01156,334,298 - 156,440,327 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.01154,536,592 - 154,599,515 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1154,579,949 - 154,599,430 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1156,335,279 - 156,354,353 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01160,800,567 - 160,863,654 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41146,977,959 - 147,084,664 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1142,493,600 - 142,599,739 (+)NCBICelera
Cytogenetic Map1q32NCBI
Sytl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554147,104,268 - 7,174,001 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554147,104,239 - 7,172,791 (+)NCBIChiLan1.0ChiLan1.0
SYTL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2986,616,996 - 86,773,315 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11187,664,954 - 87,823,384 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01180,749,861 - 80,866,479 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11184,358,095 - 84,474,422 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1184,358,155 - 84,421,509 (-)Ensemblpanpan1.1panPan2
SYTL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12113,639,054 - 13,756,332 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2113,688,338 - 13,755,414 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2113,505,757 - 13,623,017 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02113,819,767 - 13,937,016 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2113,819,798 - 13,937,013 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12113,608,437 - 13,725,706 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02113,680,690 - 13,797,966 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02113,733,418 - 13,850,744 (+)NCBIUU_Cfam_GSD_1.0
Sytl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494771,978,205 - 72,082,188 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649813,577,795 - 13,681,808 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649813,577,839 - 13,681,782 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYTL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl919,617,293 - 19,734,633 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1919,617,287 - 19,763,439 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2921,887,423 - 22,023,108 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sytl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248454,092,206 - 4,220,599 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008020392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008020416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038005396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_008020395   ⟹   XP_008018586
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,937,076 - 76,980,985 (-)NCBI
Vero_WHO_p1.0NW_02366604348,752,542 - 48,785,835 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008020398   ⟹   XP_008018589
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,937,076 - 77,061,862 (-)NCBI
Vero_WHO_p1.0NW_02366604348,660,523 - 48,785,835 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008020399   ⟹   XP_008018590
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,937,076 - 77,061,862 (-)NCBI
Vero_WHO_p1.0NW_02366604348,660,522 - 48,785,835 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008020400   ⟹   XP_008018591
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,937,076 - 77,061,862 (-)NCBI
Vero_WHO_p1.0NW_02366604348,660,522 - 48,785,835 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008020401   ⟹   XP_008018592
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,937,076 - 77,061,862 (-)NCBI
Vero_WHO_p1.0NW_02366604348,660,522 - 48,785,835 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008020403   ⟹   XP_008018594
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,937,076 - 77,061,860 (-)NCBI
Vero_WHO_p1.0NW_02366604348,660,523 - 48,785,835 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008020404   ⟹   XP_008018595
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,937,076 - 77,061,860 (-)NCBI
Vero_WHO_p1.0NW_02366604348,660,523 - 48,785,835 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008020405   ⟹   XP_008018596
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,937,076 - 77,061,860 (-)NCBI
Vero_WHO_p1.0NW_02366604348,660,523 - 48,785,832 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008020406   ⟹   XP_008018597
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,937,076 - 76,961,894 (-)NCBI
Vero_WHO_p1.0NW_02366604348,762,484 - 48,785,835 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008020414   ⟹   XP_008018605
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,937,076 - 76,961,929 (-)NCBI
Vero_WHO_p1.0NW_02366604348,760,463 - 48,785,835 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008020415   ⟹   XP_008018606
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,937,076 - 76,968,220 (-)NCBI
Vero_WHO_p1.0NW_02366604348,660,500 - 48,785,835 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008020416   ⟹   XP_008018607
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1176,937,076 - 76,968,219 (-)NCBI
Vero_WHO_p1.0NW_02366604348,752,489 - 48,785,835 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038005389   ⟹   XP_037861317
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604348,660,501 - 48,785,835 (+)NCBI
RefSeq Acc Id: XM_038005390   ⟹   XP_037861318
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604348,660,503 - 48,785,835 (+)NCBI
RefSeq Acc Id: XM_038005391   ⟹   XP_037861319
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604348,660,500 - 48,785,835 (+)NCBI
RefSeq Acc Id: XM_038005392   ⟹   XP_037861320
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604348,760,463 - 48,785,835 (+)NCBI
RefSeq Acc Id: XM_038005393   ⟹   XP_037861321
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604348,760,463 - 48,785,835 (+)NCBI
RefSeq Acc Id: XM_038005394   ⟹   XP_037861322
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604348,760,460 - 48,785,835 (+)NCBI
RefSeq Acc Id: XM_038005395   ⟹   XP_037861323
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604348,760,460 - 48,785,835 (+)NCBI
RefSeq Acc Id: XM_038005396   ⟹   XP_037861324
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366604348,760,996 - 48,785,835 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008018592   ⟸   XM_008020401
- Peptide Label: isoform X9
RefSeq Acc Id: XP_008018590   ⟸   XM_008020399
- Peptide Label: isoform X7
RefSeq Acc Id: XP_008018591   ⟸   XM_008020400
- Peptide Label: isoform X8
RefSeq Acc Id: XP_008018589   ⟸   XM_008020398
- Peptide Label: isoform X6
RefSeq Acc Id: XP_008018596   ⟸   XM_008020405
- Peptide Label: isoform X12
RefSeq Acc Id: XP_008018595   ⟸   XM_008020404
- Peptide Label: isoform X11
RefSeq Acc Id: XP_008018594   ⟸   XM_008020403
- Peptide Label: isoform X10
RefSeq Acc Id: XP_008018586   ⟸   XM_008020395
- Peptide Label: isoform X5
RefSeq Acc Id: XP_008018606   ⟸   XM_008020415
- Peptide Label: isoform X2
RefSeq Acc Id: XP_008018607   ⟸   XM_008020416
- Peptide Label: isoform X4
- UniProtKB: A0A0D9QUK2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008018605   ⟸   XM_008020414
- Peptide Label: isoform X13
RefSeq Acc Id: XP_008018597   ⟸   XM_008020406
- Peptide Label: isoform X13
RefSeq Acc Id: XP_037861319   ⟸   XM_038005391
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037861317   ⟸   XM_038005389
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037861318   ⟸   XM_038005390
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037861322   ⟸   XM_038005394
- Peptide Label: isoform X13
RefSeq Acc Id: XP_037861323   ⟸   XM_038005395
- Peptide Label: isoform X13
RefSeq Acc Id: XP_037861320   ⟸   XM_038005392
- Peptide Label: isoform X13
RefSeq Acc Id: XP_037861321   ⟸   XM_038005393
- Peptide Label: isoform X13
RefSeq Acc Id: XP_037861324   ⟸   XM_038005396
- Peptide Label: isoform X13


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000003677 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000001699.1 UniProtKB/TrEMBL
Gene3D-CATH C2 domain UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  SYTL1-5_C2B UniProtKB/TrEMBL
NCBI Gene SYTL2 ENTREZGENE
PANTHER BITESIZE, ISOFORM I UniProtKB/TrEMBL
  SYNAPTOTAGMIN-LIKE PROTEIN 2 UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP C2 domain (Calcium/lipid-binding domain, CaLB) UniProtKB/TrEMBL
UniProt A0A0D9QUK2 ENTREZGENE, UniProtKB/TrEMBL