F2RL3 (F2R like thrombin or trypsin receptor 3) - Rat Genome Database

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Gene: F2RL3 (F2R like thrombin or trypsin receptor 3) Chlorocebus sabaeus
Analyze
Symbol: F2RL3
Name: F2R like thrombin or trypsin receptor 3
RGD ID: 18622580
Description: ENCODES a protein that exhibits protease binding (ortholog); INVOLVED IN platelet activation (ortholog); platelet aggregation (ortholog); positive regulation of release of sequestered calcium ion into cytosol (ortholog); PARTICIPATES IN protease mediated signaling via protease-activated receptor 4; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); cholestasis (ortholog); genetic disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F2R like thrombin/trypsin receptor 3; proteinase-activated receptor 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1615,397,552 - 15,400,708 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660744,036,812 - 4,040,135 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
F2RL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1615,397,552 - 15,400,708 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660744,036,812 - 4,040,135 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
F2RL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381916,888,999 - 16,892,606 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1916,888,999 - 16,892,606 (+)EnsemblGRCh38hg38GRCh38
GRCh371916,999,810 - 17,003,417 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361916,860,826 - 16,863,830 (+)NCBINCBI36Build 36hg18NCBI36
Build 341916,860,825 - 16,870,516NCBI
Celera1916,901,357 - 16,904,361 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1916,568,368 - 16,571,379 (+)NCBIHuRef
CHM1_11916,999,569 - 17,002,573 (+)NCBICHM1_1
T2T-CHM13v2.01917,023,836 - 17,027,443 (+)NCBIT2T-CHM13v2.0
F2rl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39873,488,287 - 73,490,526 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl873,488,508 - 73,490,502 (+)EnsemblGRCm39 Ensembl
GRCm38872,761,659 - 72,763,898 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl872,761,880 - 72,763,874 (+)EnsemblGRCm38mm10GRCm38
MGSCv37875,285,779 - 75,287,784 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36875,657,952 - 75,659,957 (+)NCBIMGSCv36mm8
Celera877,077,985 - 77,079,990 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map835.08NCBI
F2rl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81617,151,516 - 17,153,509 (-)NCBIGRCr8
mRatBN7.21617,117,441 - 17,119,434 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1617,117,441 - 17,119,472 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1617,185,458 - 17,187,486 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01618,317,104 - 18,319,112 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01617,238,362 - 17,240,390 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01618,817,797 - 18,819,790 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1618,814,622 - 18,819,833 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01618,687,984 - 18,689,977 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1617,341,816 - 17,343,823 (-)NCBICelera
Cytogenetic Map16p14NCBI
F2rl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555241,044,792 - 1,047,819 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555241,045,493 - 1,047,924 (-)NCBIChiLan1.0ChiLan1.0
F2RL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22021,757,541 - 21,762,253 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11920,764,020 - 20,768,733 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01916,375,572 - 16,379,587 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11917,355,542 - 17,357,628 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1917,355,542 - 17,357,628 (+)Ensemblpanpan1.1panPan2
F2RL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12045,738,587 - 45,740,564 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2045,738,587 - 45,740,473 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2045,652,073 - 45,655,003 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02046,224,593 - 46,227,523 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2046,225,014 - 46,226,479 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12045,460,781 - 45,463,709 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02045,871,392 - 45,874,323 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02046,146,994 - 46,149,271 (-)NCBIUU_Cfam_GSD_1.0
F2RL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl260,742,996 - 60,744,864 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1260,742,978 - 60,747,014 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2260,307,031 - 60,309,288 (-)NCBISscrofa10.2Sscrofa10.2susScr3
F2rl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624908762,356 - 766,563 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624908761,067 - 764,562 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007995666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_007995666   ⟹   XP_007993857
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1615,397,552 - 15,400,708 (+)NCBI
Vero_WHO_p1.0NW_0236660744,036,812 - 4,040,135 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007993857 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000001996.1
Reference Protein Sequences
RefSeq Acc Id: XP_007993857   ⟸   XM_007995666
- UniProtKB: A0A0D9R057 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005687 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003725.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Prot_act_rcpt_4 UniProtKB/TrEMBL
  Protea_act_rcpt UniProtKB/TrEMBL
NCBI Gene F2RL3 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  PROTEINASE-ACTIVATED RECEPTOR 4 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  PROTEASEAR UniProtKB/TrEMBL
  PROTEASEAR4 UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0D9R057 ENTREZGENE, UniProtKB/TrEMBL