dichlorine - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	dichlorine	go back to main search page
Accession:	CHEBI:29310	browse the term
Definition:	A diatomic chlorine that has formula Cl2.
Synonyms:	related_synonym:	Cl2; Formula=Cl2; InChI=1S/Cl2/c1-2; InChIKey=KZBUYRJDOAKODT-UHFFFAOYSA-N; SMILES=ClCl; chlorine; molecular chlorine
	xref:	Beilstein:3902968; CAS:7782-50-5; Gmelin:788
	xref_mesh:	MESH:D002713

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Rat (380) Mouse (381) Human (379) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (14) Green Monkey (0) Naked Mole-rat (0) All
Genes (380)

dichlorine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP-binding cassette, sub-family B member 1B

increases expression
multiple interactions

Chlorine results in increased expression of ABCB1B mRNA
[Ozone co-treated with Chlorine] results in decreased expression of ABCB1B mRNA

NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199

G

ATP binding cassette subfamily C member 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ABCC1 mRNA

NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114

G

acyl-CoA dehydrogenase medium chain

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ACADM mRNA

NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147

G

acetylcholinesterase

multiple interactions

[[Chlorine co-treated with Diazinon] results in increased abundance of diazoxon] which results in decreased activity of ACHE protein

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

acyl-CoA thioesterase 7

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of ACOT7 mRNA

NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309

G

acyl-CoA synthetase long-chain family member 1

decreases expression
multiple interactions

Chlorine results in decreased expression of ACSL1 mRNA
[Ozone co-treated with Chlorine] affects the expression of ACSL1 mRNA

NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541

G

activin A receptor type 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ACVR1 mRNA

NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241

G

adenylate cyclase 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ADCY2 mRNA

NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236

G

adenylate cyclase 3

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of ADCY3 mRNA

NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686

G

adenylate cyclase 4

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of ADCY4 mRNA

NCBI chr15:29,266,280...29,282,153
Ensembl chr15:29,266,287...29,282,108

G

adenylate cyclase 5

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ADCY5 mRNA

NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974

G

adenylate cyclase 8

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ADCY8 mRNA

NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911

G

adhesion G protein-coupled receptor L1

decreases expression
multiple interactions

Chlorine results in decreased expression of ADGRL1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of ADGRL1 mRNA

NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139

G

adenosine A3 receptor

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ADORA3 mRNA

NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357

G

adrenoceptor alpha 2C

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ADRA2C mRNA

NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846

G

adrenoceptor beta 2

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of ADRB2 mRNA

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

G

advanced glycosylation end product-specific receptor

decreases expression
multiple interactions
increases expression

Chlorine results in decreased expression of AGER mRNA
[Ozone co-treated with Chlorine] results in increased expression of AGER mRNA
Chlorine results in increased expression of AGER protein

PMID:18636392 PMID:36690086

NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078

G

aldo-keto reductase family 1 member A1

increases expression
multiple interactions

Chlorine results in increased expression of AKR1A1 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of AKR1A1 mRNA

NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674

G

AKT serine/threonine kinase 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of AKT1 mRNA

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

AKT serine/threonine kinase 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of AKT2 mRNA

NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817

G

aldolase, fructose-bisphosphate C

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ALDOC mRNA

NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066

G

alpha-methylacyl-CoA racemase

increases expression
multiple interactions

Chlorine results in increased expression of AMACR mRNA
[Ozone co-treated with Chlorine] results in increased expression of AMACR mRNA

NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255

G

amphiphysin

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of AMPH mRNA

NCBI chr17:45,739,385...45,982,905
Ensembl chr17:45,739,395...45,983,315

G

annexin A2

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in decreased expression of ANXA2 mRNA
Chlorine results in increased expression of ANXA2 mRNA

NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658

G

annexin A3

increases expression
multiple interactions

Chlorine results in increased expression of ANXA3 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of ANXA3 mRNA

NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617

G

annexin A4

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ANXA4 mRNA

NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161

G

annexin A5

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ANXA5 mRNA

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

G

APC regulator of WNT signaling pathway

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of APC mRNA

NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696

G

apurinic/apyrimidinic endodeoxyribonuclease 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of APEX1 mRNA

NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785

G

apolipoprotein A1

multiple interactions
affects binding

[MPO protein binds to and results in increased oxidation of APOA1 protein] promotes the reaction [APOA1 protein binds to Chlorine]; [MPO protein promotes the reaction [APOA1 protein binds to Chlorine]] which results in decreased activity of LCAT protein

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

G

apolipoprotein D

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of APOD mRNA

NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305

G

aquaporin 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of AQP1 mRNA

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

G

aquaporin 3 (Gill blood group)

decreases expression
multiple interactions

Chlorine results in decreased expression of AQP3 mRNA
[Ozone co-treated with Chlorine] affects the expression of AQP3 mRNA

NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720

G

ADP-ribosylation factor 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ARF1 mRNA

NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434

G

ADP-ribosylation factor 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ARF3 mRNA

NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002

G

ADP-ribosylation factor 4

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ARF4 mRNA

NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261

G

ADP-ribosylation factor 5

increases expression
multiple interactions

Chlorine results in increased expression of ARF5 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of ARF5 mRNA

NCBI chr 4:57,038,521...57,041,447
Ensembl chr 4:57,038,521...57,041,441

G

ADP-ribosylation factor 6

increases expression
multiple interactions

Chlorine results in increased expression of ARF6 mRNA
[Ozone co-treated with Chlorine] affects the expression of ARF6 mRNA

NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114

G

arginase 1

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of ARG1 mRNA
Chlorine results in increased expression of ARG1 mRNA; Chlorine results in increased expression of ARG1 protein

PMID:18636392 PMID:24582687 PMID:30189237

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

Rho GTPase activating protein 35

decreases expression
multiple interactions

Chlorine results in decreased expression of ARHGAP35 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of ARHGAP35 mRNA

NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298

G

arrestin, beta 2

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of ARRB2 mRNA

NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850

G

activating transcription factor 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ATF2 mRNA

NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236

G

ATPase Na+/K+ transporting subunit alpha 1

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] results in decreased expression of ATP1A1 mRNA
Chlorine results in decreased expression of ATP1A1 mRNA

PMID:18636392 PMID:24218892

NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3

decreases expression
multiple interactions

Chlorine results in decreased expression of ATP2A3 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of ATP2A3 mRNA

NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748

G

ATPase H+ transporting V0 subunit C

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ATP6V0C mRNA

NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500

G

ATPase copper transporting beta

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ATP7B mRNA

NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636

G

BCL2 associated X, apoptosis regulator

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of BAX mRNA

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

bradykinin receptor B2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of BDKRB2 mRNA

NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497

G

bone morphogenetic protein 4

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of BMP4 mRNA

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

G

complement C5a receptor 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of C5AR1 mRNA

NCBI chr 1:76,948,622...76,959,826

G

calcium voltage-gated channel subunit alpha1 A

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of CACNA1A mRNA

NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225

G

calcium voltage-gated channel subunit alpha1 B

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of CACNA1B mRNA

NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091

G

calcium voltage-gated channel auxiliary subunit beta 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CACNB3 mRNA

NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074

G

carbonic anhydrase 3

decreases expression
multiple interactions

Chlorine results in decreased expression of CA3 mRNA
[Ozone co-treated with Chlorine] affects the expression of CA3 mRNA

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

CART prepropeptide

decreases expression
multiple interactions

Chlorine results in decreased expression of CARTPT mRNA
[Ozone co-treated with Chlorine] affects the expression of CARTPT mRNA

NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713

G

caspase 3

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of CASP3 mRNA

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

calcium-sensing receptor

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CASR mRNA

NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811

G

calpastatin

increases expression
multiple interactions

Chlorine results in increased expression of CAST mRNA
[Ozone co-treated with Chlorine] affects the expression of CAST mRNA

NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659

G

catalase

increases expression
multiple interactions

Chlorine results in increased expression of CAT protein
Acetylcysteine inhibits the reaction [Chlorine results in increased expression of CAT protein]

PMID:35065218 PMID:36690086

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

cholecystokinin B receptor

decreases expression
multiple interactions

Chlorine results in decreased expression of CCKBR mRNA
[Ozone co-treated with Chlorine] results in increased expression of CCKBR mRNA

NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881

G

C-C motif chemokine ligand 11

increases expression

Chlorine results in increased expression of CCL11 protein

NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926

G

C-C motif chemokine ligand 12

increases expression

Chlorine results in increased expression of CCL12 mRNA

NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780

G

C-C motif chemokine ligand 2

increases expression
decreases secretion
multiple interactions

Chlorine results in increased expression of CCL2 mRNA; Chlorine results in increased expression of CCL2 protein
Chlorine results in decreased secretion of CCL2 protein
Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of CCL2 protein]

PMID:23146759 PMID:24582687 PMID:30189237 PMID:35065218

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 20

increases expression

Chlorine results in increased expression of CCL20 mRNA

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 3

increases expression

Chlorine results in increased expression of CCL3 protein

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 5

increases expression
multiple interactions

Chlorine results in increased expression of CCL5 protein
[Chlorine binds to Cytidine] which results in decreased expression of CCL5 mRNA

PMID:23146759 PMID:31066272

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

C-C motif chemokine ligand 7

increases expression

Chlorine results in increased expression of CCL7 mRNA

NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303

G

C-C motif chemokine ligand 9

increases expression

Chlorine results in increased expression of CCL6 mRNA

NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369

G

cyclin C

increases expression
multiple interactions

Chlorine results in increased expression of CCNC mRNA
[Ozone co-treated with Chlorine] results in decreased expression of CCNC mRNA

NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584

G

cyclin D1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CCND1 mRNA

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CCND3 mRNA

NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371

G

cyclin G1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CCNG1 mRNA

NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641

G

Cd4 molecule

decreases expression
multiple interactions

Chlorine results in decreased expression of CD4 mRNA
[Ozone co-treated with Chlorine] affects the expression of CD4 mRNA

NCBI chr 4:157,668,878...157,695,366

G

CD44 molecule

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of CD44 mRNA

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

G

CD9 molecule

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CD9 mRNA

NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222

G

cell division cycle 25B

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of CDC25B mRNA

NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272

G

cadherin 22

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of CDH22 mRNA

NCBI chr 3:153,845,563...153,970,630
Ensembl chr 3:153,845,787...153,970,588

G

cyclin-dependent kinase 4

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CDK4 mRNA

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1A

increases expression
multiple interactions

Chlorine results in increased expression of CDKN1A mRNA
[Ozone co-treated with Chlorine] affects the expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 2B

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CDKN2B mRNA

NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050

G

cofilin 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CFL1 mRNA

NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587

G

CF transmembrane conductance regulator

multiple interactions
increases transport

CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]; Nitric Oxide inhibits the reaction [CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]]
CFTR protein results in increased transport of Chlorine

PMID:12612912 PMID:21765217

NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756

G

cholinergic receptor nicotinic alpha 1 subunit

increases expression
multiple interactions

Chlorine results in increased expression of CHRNA1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of CHRNA1 mRNA

NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840

G

cholinergic receptor nicotinic alpha 4 subunit

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of CHRNA4 mRNA

NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957

G

cholinergic receptor nicotinic beta 1 subunit

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of CHRNB1 mRNA

NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345

G

creatine kinase, mitochondrial 1

affects expression
multiple interactions

Chlorine affects the expression of CKMT1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of CKMT1 mRNA

NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758

G

C-type lectin domain family 4, member D

increases expression

Chlorine results in increased expression of CLEC4D mRNA

NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848

G

clusterin

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in decreased expression of CLU mRNA
Acetylcysteine promotes the reaction [Chlorine results in increased expression of CLU protein]

PMID:18636392 PMID:35065218

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

G

chemerin chemokine-like receptor 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CMKLR1 mRNA

NCBI chr12:42,974,462...43,027,321
Ensembl chr12:42,974,410...43,028,129

G

calponin 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CNN3 mRNA

NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104

G

cannabinoid receptor 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of CNR1 mRNA

NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099

G

carboxypeptidase D

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CPD mRNA

NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491

G

carnitine palmitoyltransferase 1B

increases expression
multiple interactions

Chlorine results in increased expression of CPT1B mRNA
[Ozone co-treated with Chlorine] results in decreased expression of CPT1B mRNA

NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404

G

corticotropin releasing hormone receptor 2

increases expression
multiple interactions

Chlorine results in increased expression of CRHR2 mRNA
[Ozone co-treated with Chlorine] affects the expression of CRHR2 mRNA

NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904

G

CRK proto-oncogene, adaptor protein

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CRK mRNA

NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406

G

colony stimulating factor 1 receptor

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of CSF1R mRNA

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

G

colony stimulating factor 2

increases expression

Chlorine results in increased expression of CSF2 protein

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

colony stimulating factor 3

increases expression
multiple interactions

Chlorine results in increased expression of CSF3 mRNA
[Ozone co-treated with Chlorine] results in increased expression of CSF3 mRNA
Chlorine results in increased expression of CSF3 protein

PMID:18636392 PMID:23146759

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

casein kinase 1, gamma 1

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] results in increased expression of CSNK1G1 mRNA
Chlorine results in decreased expression of CSNK1G1 mRNA

NCBI chr 8:66,439,760...66,577,247
Ensembl chr 8:66,439,864...66,572,826

G

cysteine and glycine rich protein 3

increases expression
multiple interactions

Chlorine results in increased expression of CSRP3 mRNA
[Ozone co-treated with Chlorine] results in increased expression of CSRP3 mRNA

NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653

G

cathepsin B

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CTSB mRNA

NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500

G

cathepsin L

increases expression
multiple interactions

Chlorine results in increased expression of CTSL mRNA
[Ozone co-treated with Chlorine] results in decreased expression of CTSL mRNA

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

C-X-C motif chemokine ligand 10

decreases expression
multiple interactions

Chlorine results in decreased expression of CXCL10 mRNA
[Ozone co-treated with Chlorine] results in increased expression of CXCL10 mRNA

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 3

multiple interactions
increases expression

triptolide inhibits the reaction [Chlorine results in increased expression of CXCL1 protein]
Chlorine results in increased expression of CXCL1 mRNA; Chlorine results in increased expression of CXCL1 protein

PMID:20348278 PMID:20819911 PMID:23146759 PMID:24582687

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine receptor 4

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CXCR4 mRNA

NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883

G

cytochrome P450, family 11, subfamily a, polypeptide 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of CYP11A1 mRNA

NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 19, subfamily a, polypeptide 1

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of CYP19A1 mRNA
Chlorine results in increased expression of CYP19A1 mRNA

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, subfamily 2, polypeptide 11

decreases expression
multiple interactions

Chlorine results in decreased expression of CYP2C mRNA
[Ozone co-treated with Chlorine] affects the expression of CYP2C mRNA

NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450, family 4, subfamily a, polypeptide 3

decreases expression
multiple interactions

Chlorine results in decreased expression of CYP4A3 mRNA
[Ozone co-treated with Chlorine] affects the expression of CYP4A3 mRNA

NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463

G

cytochrome P450, family 4, subfamily f, polypeptide 4

decreases expression
multiple interactions

Chlorine results in decreased expression of CYP4F4 mRNA
[Ozone co-treated with Chlorine] affects the expression of CYP4F4 mRNA

NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506

G

dopa decarboxylase

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of DDC mRNA
Chlorine results in decreased expression of DDC mRNA

NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208

G

DNA-damage inducible transcript 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of DDIT3 mRNA

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

dipeptidylpeptidase 4

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of DPP4 mRNA

NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901

G

dipeptidyl peptidase like 6

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of DPP6 mRNA

NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532

G

dopamine receptor D1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of DRD1 mRNA

NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002

G

eukaryotic translation elongation factor 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of EEF2 mRNA

NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183

G

early growth response 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of EGR1 mRNA

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

eukaryotic translation initiation factor 2 subunit alpha

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of EIF2S1 mRNA

NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225

G

eukaryotic translation initiation factor 5

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of EIF5 mRNA

NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656

G

coagulation factor II, thrombin

decreases expression
multiple interactions

Chlorine results in decreased expression of F2 mRNA
[Ozone co-treated with Chlorine] affects the expression of F2 mRNA

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

G

fatty acid amide hydrolase

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of FAAH mRNA

NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677

G

fatty acid binding protein 1

decreases expression
multiple interactions

Chlorine results in decreased expression of FABP1 mRNA
[Ozone co-treated with Chlorine] affects the expression of FABP1 mRNA

NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788

G

fatty acid binding protein 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of FABP2 mRNA

NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089

G

fatty acid binding protein 4

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of FABP4 mRNA

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

fatty acid binding protein 5

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of FABP5 mRNA

NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773

G

Fas cell surface death receptor

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of FAS mRNA

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

fibroblast growth factor 10

decreases expression
multiple interactions

Chlorine results in decreased expression of FGF10 mRNA
[Ozone co-treated with Chlorine] affects the expression of FGF10 mRNA

NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866

G

fibroblast growth factor 2

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of FGF2 mRNA
Chlorine results in decreased expression of FGF2 mRNA

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

FGR proto-oncogene, Src family tyrosine kinase

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of FGR mRNA

NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326

G

Fos proto-oncogene, AP-1 transcription factor subunit

decreases expression
multiple interactions

Chlorine results in decreased expression of FOS mRNA
[Ozone co-treated with Chlorine] affects the expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

FOS like 1, AP-1 transcription factor subunit

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of FOSL1 mRNA

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

gamma-aminobutyric acid type B receptor subunit 1

decreases expression
multiple interactions

Chlorine results in decreased expression of GABBR1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of GABBR1 mRNA

NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994

G

galanin receptor 1

decreases expression
multiple interactions

Chlorine results in decreased expression of GALR1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of GALR1 mRNA

NCBI chr18:75,772,021...75,787,577
Ensembl chr18:75,772,023...75,787,577

G

glyceraldehyde-3-phosphate dehydrogenase

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GAPDH mRNA

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

G

glucagon receptor

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of GCGR mRNA

NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640

G

glutamate cysteine ligase, modifier subunit

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GCLM mRNA

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

GDP dissociation inhibitor 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GDI1 mRNA

NCBI chr X:152,087,611...152,094,274
Ensembl chr X:152,087,444...152,094,272

G

GDP dissociation inhibitor 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GDI2 mRNA

NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366

G

growth hormone receptor

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of GHR mRNA
Chlorine results in decreased expression of GHR mRNA

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

G

gastric inhibitory polypeptide receptor

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of GIPR mRNA

NCBI chr 1:78,804,287...78,814,462
Ensembl chr 1:78,805,593...78,814,462

G

glia maturation factor, beta

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GMFB mRNA

NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331

G

G protein subunit alpha i1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GNAI1 mRNA

NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417

G

G protein subunit alpha i2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GNAI2 mRNA

NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979

G

G protein subunit alpha o1

decreases expression
multiple interactions

Chlorine results in decreased expression of GNAO1 mRNA
[Ozone co-treated with Chlorine] affects the expression of GNAO1 mRNA

NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493

G

GNAS complex locus

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GNAS mRNA

NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

G

G protein subunit alpha z

increases expression
multiple interactions

Chlorine results in increased expression of GNAZ mRNA
[Ozone co-treated with Chlorine] results in increased expression of GNAZ mRNA

NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907

G

G protein subunit beta 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GNB1 mRNA

NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124

G

glutathione peroxidase 3

increases expression
multiple interactions

Chlorine results in increased expression of GPX3 mRNA
[Ozone co-treated with Chlorine] affects the expression of GPX3 mRNA

NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035

G

glutathione peroxidase 5

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of GPX5 mRNA
Chlorine results in increased expression of GPX5 mRNA

NCBI chr17:43,436,126...43,443,074
Ensembl chr17:43,416,340...43,443,074

G

G protein-coupled receptor kinase 3

increases expression
multiple interactions

Chlorine results in increased expression of GRK3 mRNA
[Ozone co-treated with Chlorine] results in increased expression of GRK3 mRNA

NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262

G

glutathione-disulfide reductase

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of GSR mRNA

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione synthetase

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in decreased expression of GSS mRNA
Chlorine results in increased expression of GSS mRNA

NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198

G

glutathione S-transferase alpha 4

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of GSTA4 mRNA
Chlorine results in decreased expression of GSTA4 mRNA

NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182

G

glutathione S-transferase kappa 1

increases expression
multiple interactions

Chlorine results in increased expression of GSTK1 mRNA
[Ozone co-treated with Chlorine] affects the expression of GSTK1 mRNA

NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292

G

glutathione S-transferase mu 2

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of GSTM2 mRNA
Chlorine results in decreased expression of GSTM2 mRNA

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase theta 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of GSTT2 mRNA

NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288

G

guanylate cyclase 2E

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of GUCY2D mRNA

NCBI chr10:53,954,918...53,975,576
Ensembl chr10:53,959,010...53,974,067

G

H2A.X variant histone

increases expression

Chlorine results in increased expression of H2AX protein

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

decreases expression
multiple interactions

Chlorine results in decreased expression of HMGCS2 mRNA
[Ozone co-treated with Chlorine] affects the expression of HMGCS2 mRNA

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

heme oxygenase 1

increases expression

Chlorine results in increased expression of HMOX1 protein

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heme oxygenase 2

increases expression

Chlorine results in increased expression of HMOX2 protein

NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148

G

hippocalcin-like 4

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of HPCAL4 mRNA

NCBI chr 5:135,454,477...135,466,417
Ensembl chr 5:135,454,540...135,466,416

G

hypoxanthine phosphoribosyltransferase 1

increases expression
multiple interactions

Chlorine results in increased expression of HPRT1 mRNA
[Ozone co-treated with Chlorine] affects the expression of HPRT1 mRNA

NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154

G

HRas proto-oncogene, GTPase

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of HRAS mRNA

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

decreases expression
multiple interactions

Chlorine results in decreased expression of HSD3B1 mRNA
[Ozone co-treated with Chlorine] affects the expression of HSD3B1 mRNA

NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999

G

heat shock protein family A (Hsp70) member 5

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of HSPA5 mRNA

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family D (Hsp60) member 1

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in decreased expression of HSPD1 mRNA
Acetylcysteine inhibits the reaction [Chlorine results in increased expression of HSPD1 protein]

PMID:18636392 PMID:35065218

NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662

G

5-hydroxytryptamine receptor 1F

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of HTR1F mRNA

NCBI chr11:2,642,751...2,644,150
Ensembl chr11:2,642,751...2,644,150

G

5-hydroxytryptamine receptor 6

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of HTR6 mRNA

NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912

G

huntingtin

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of HTT mRNA

NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070

G

inhibitor of DNA binding 2

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of ID2 mRNA
Chlorine results in decreased expression of ID2 mRNA

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

interferon gamma

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of IFNG mRNA
Chlorine results in increased expression of IFNG protein

PMID:18636392 PMID:23146759

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

insulin-like growth factor binding protein, acid labile subunit

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of IGFALS mRNA

NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677

G

insulin-like growth factor binding protein 3

decreases expression
multiple interactions

Chlorine results in decreased expression of IGFBP3 mRNA
[Ozone co-treated with Chlorine] affects the expression of IGFBP3 mRNA

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

interleukin 12A

increases expression

Chlorine results in increased expression of IL12A protein

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

G

interleukin 12B

increases expression

Chlorine results in increased expression of IL12B protein

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

G

interleukin 13

increases expression

Chlorine results in increased expression of IL13 protein

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 18

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of IL18 mRNA

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 beta

multiple interactions
increases expression
affects expression

[Ozone co-treated with Chlorine] results in increased expression of IL1B mRNA
Chlorine results in increased expression of IL1B protein
Chlorine affects the expression of IL1B mRNA
[Chlorine binds to Cytidine] which results in increased expression of IL1B mRNA; [Chlorine binds to Cytidine] which results in increased expression of IL1B protein

PMID:18636392 PMID:23146759 PMID:24582687 PMID:31066272

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor-like 1

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] results in decreased expression of IL1RL1 mRNA
Chlorine results in decreased expression of IL1RL1 mRNA

NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256

G

interleukin 4 receptor

increases expression

Chlorine results in increased expression of IL4RA mRNA

NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980

G

interleukin 6

increases expression
multiple interactions
decreases secretion

Chlorine results in increased expression of IL6 mRNA; Chlorine results in increased expression of IL6 protein
Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of IL6 protein]

PMID:23146759 PMID:30189237 PMID:35065218

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

inhibin subunit beta A

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of INHBA mRNA

NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982

G

insulin receptor-related receptor

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of INSRR mRNA

NCBI chr 2:173,255,335...173,274,800
Ensembl chr 2:173,255,414...173,274,800

G

integrin subunit alpha 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ITGA1 mRNA

NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238

G

integrin subunit beta 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ITGB1 mRNA

NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195

G

inositol 1,4,5-trisphosphate receptor, type 3

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ITPR3 mRNA

NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337

G

Jun proto-oncogene, AP-1 transcription factor subunit

decreases expression
multiple interactions

Chlorine results in decreased expression of JUN mRNA
[Ozone co-treated with Chlorine] affects the expression of JUN mRNA

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

junction plakoglobin

increases expression
multiple interactions

Chlorine results in increased expression of JUP mRNA
[Ozone co-treated with Chlorine] results in decreased expression of JUP mRNA

NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057

G

potassium voltage-gated channel subfamily A member 4

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of KCNA4 mRNA

NCBI chr 3:93,756,399...93,778,004
Ensembl chr 3:93,756,446...93,769,162

G

potassium voltage-gated channel subfamily B member 1

affects expression
multiple interactions

Chlorine affects the expression of KCNB1 mRNA
[Ozone co-treated with Chlorine] affects the expression of KCNB1 mRNA

NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194

G

potassium voltage-gated channel subfamily D member 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of KCND2 mRNA

NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728

G

potassium inwardly-rectifying channel, subfamily J, member 4

decreases expression
multiple interactions

Chlorine results in decreased expression of KCNJ4 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of KCNJ4 mRNA

NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151

G

potassium inwardly-rectifying channel, subfamily J, member 5

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of KCNJ5 mRNA

NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518

G

potassium inwardly-rectifying channel, subfamily J, member 8

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of KCNJ8 mRNA

NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603

G

kallikrein B1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of KLKB1 mRNA

NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053

G

KRAS proto-oncogene, GTPase

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of KRAS mRNA

NCBI chr 4:178,185,418...178,218,484

G

lecithin cholesterol acyltransferase

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of LCAT mRNA
Chlorine results in decreased expression of LCAT mRNA
[MPO protein promotes the reaction [APOA1 protein binds to Chlorine]] which results in decreased activity of LCAT protein

PMID:18636392 PMID:33861588

NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231

G

LIM domain kinase 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of LIMK1 mRNA

NCBI chr12:22,026,697...22,060,605
Ensembl chr12:22,026,672...22,060,606

G

lipase C, hepatic type

decreases expression
multiple interactions

Chlorine results in decreased expression of LIPC mRNA
[Ozone co-treated with Chlorine] results in increased expression of LIPC mRNA

NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464

G

lipase E, hormone sensitive type

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of LIPE mRNA

NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310

G

LYN proto-oncogene, Src family tyrosine kinase

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in increased expression of LYN mRNA
Chlorine results in increased expression of LYN mRNA

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

G

mal, T-cell differentiation protein

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of MAL mRNA

NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136

G

mitogen activated protein kinase kinase 1

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in decreased expression of MAP2K1 mRNA
Chlorine results in increased expression of MAP2K1 mRNA

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MAPK1 mRNA

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MAPK3 mRNA

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

MYC associated factor X

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MAX mRNA

NCBI chr 6:95,636,859...95,662,204
Ensembl chr 6:95,636,858...95,662,137

G

melanocortin 4 receptor

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of MC4R mRNA

NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719

G

methyl CpG binding protein 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MECP2 mRNA

NCBI chr X:151,781,177...151,844,687
Ensembl chr X:151,789,930...151,844,689

G

mesenchyme homeobox 2

affects expression
multiple interactions

Chlorine affects the expression of MEOX2 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of MEOX2 mRNA

NCBI chr 6:53,856,760...53,917,467
Ensembl chr 6:53,856,758...53,917,467

G

O-6-methylguanine-DNA methyltransferase

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MGMT mRNA

NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756

G

microsomal glutathione S-transferase 1

decreases expression
multiple interactions

Chlorine results in decreased expression of MGST1 mRNA
[Ozone co-treated with Chlorine] affects the expression of MGST1 mRNA

NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892

G

matrix metallopeptidase 14

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MMP14 mRNA

NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864

G

matrix metallopeptidase 9

decreases secretion
multiple interactions
increases expression

Chlorine results in decreased secretion of MMP9 protein
Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of MMP9 protein]
Chlorine results in increased expression of MMP9 protein

PMID:35065218 PMID:36690086

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

myeloid cell nuclear differentiation antigen

increases expression

Chlorine results in increased expression of IFI204 mRNA

NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201

G

myeloperoxidase

multiple interactions

[MPO protein binds to and results in increased oxidation of APOA1 protein] promotes the reaction [APOA1 protein binds to Chlorine]; [MPO protein promotes the reaction [APOA1 protein binds to Chlorine]] which results in decreased activity of LCAT protein; MPO protein promotes the reaction [chlorodimedone binds to Chlorine]; Phenolsulfonphthalein promotes the reaction [MPO protein promotes the reaction [chlorodimedone binds to Chlorine]]

PMID:31288001 PMID:33861588

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

mannose receptor, C type 1

increases expression

Chlorine results in increased expression of MRC1 mRNA

NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857

G

MAS related GPR family member F

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of MRGPRF mRNA

NCBI chr 1:200,464,100...200,473,588
Ensembl chr 1:200,463,973...200,473,660

G

melatonin receptor 1A

decreases expression
multiple interactions

Chlorine results in decreased expression of MTNR1A mRNA
[Ozone co-treated with Chlorine] results in increased expression of MTNR1A mRNA

NCBI chr16:47,144,461...47,163,919
Ensembl chr16:47,144,461...47,163,919

G

major vault protein

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MVP mRNA

NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380

G

myosin Ib

increases expression
multiple interactions

Chlorine results in increased expression of MYO1B mRNA
[Ozone co-treated with Chlorine] affects the expression of MYO1B mRNA

NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798

G

neural EGFL like 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of NELL1 mRNA

NCBI chr 1:99,709,305...100,573,872
Ensembl chr 1:99,709,793...100,573,860

G

neural EGFL like 2

increases expression
multiple interactions

Chlorine results in increased expression of NELL2 mRNA
[Ozone co-treated with Chlorine] results in increased expression of NELL2 mRNA

NCBI chr 7:126,343,089...126,662,903
Ensembl chr 7:126,198,851...126,733,503

G

NFKB inhibitor alpha

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of NFKBIA mRNA
Chlorine results in decreased expression of NFKBIA mRNA

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

neuroglobin

affects abundance

NGB protein affects the abundance of Chlorine

NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830

G

NME/NM23 nucleoside diphosphate kinase 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of NME2 mRNA

NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538

G

nitric oxide synthase 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of NOS1 mRNA

NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945

G

nitric oxide synthase 2

increases expression

Chlorine results in increased expression of NOS2 mRNA

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

nitric oxide synthase 3

decreases activity
decreases expression

Chlorine results in decreased activity of NOS3 protein
Chlorine results in decreased expression of NOS3 protein

NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166

G

natriuretic peptide C

multiple interactions
affects expression

[Ozone co-treated with Chlorine] affects the expression of NPPC mRNA
Chlorine affects the expression of NPPC mRNA

NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251

G

neuronal pentraxin receptor

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of NPTXR mRNA

NCBI chr 7:111,336,660...111,354,737
Ensembl chr 7:111,336,664...111,354,802

G

nuclear receptor subfamily 2, group C, member 2

decreases expression
multiple interactions

Chlorine results in decreased expression of NR2C2 mRNA
[Ozone co-treated with Chlorine] affects the expression of NR2C2 mRNA

NCBI chr 4:124,610,216...124,666,813
Ensembl chr 4:124,608,960...124,661,902

G

nuclear receptor subfamily 2, group F, member 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of NR2F1 mRNA

NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123

G

nuclear receptor subfamily 3, group C, member 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of NR3C2 mRNA

NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885

G

nuclear receptor subfamily 4, group A, member 1

decreases expression
multiple interactions

Chlorine results in decreased expression of NR4A1 mRNA
[Ozone co-treated with Chlorine] affects the expression of NR4A1 mRNA

NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297

G

nuclear receptor subfamily 4, group A, member 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of NR4A3 mRNA

NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733

G

neuropilin 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of NRP2 mRNA

NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958

G

neurexin 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of NRXN1 mRNA

NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710

G

neurexin 2

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of NRXN2 mRNA

NCBI chr 1:203,726,420...203,842,301
Ensembl chr 1:203,735,753...203,842,297

G

neurotrophic receptor tyrosine kinase 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of NTRK1 mRNA

NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770

G

neurotensin receptor 2

decreases expression
multiple interactions

Chlorine results in decreased expression of NTSR2 mRNA
[Ozone co-treated with Chlorine] affects the expression of NTSR2 mRNA

NCBI chr 6:39,424,297...39,431,015
Ensembl chr 6:39,424,324...39,431,014

G

ornithine decarboxylase 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ODC1 mRNA

NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440

G

opioid receptor, kappa 1

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of OPRK1 mRNA
Chlorine results in decreased expression of OPRK1 mRNA

NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823

G

p21 (RAC1) activated kinase 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PAK1 mRNA

NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383

G

proliferating cell nuclear antigen

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of PCNA mRNA

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

proprotein convertase subtilisin/kexin type 7

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of PCSK7 mRNA

NCBI chr 8:46,202,079...46,224,699
Ensembl chr 8:46,202,131...46,224,705

G

PDGFA associated protein 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of PDAP1 mRNA

NCBI chr12:9,470,652...9,480,880
Ensembl chr12:9,470,574...9,535,374

G

phosphodiesterase 4D

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of PDE4D mRNA

NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884

G

platelet derived growth factor receptor beta

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of PDGFRB mRNA

NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843

G

protein disulfide isomerase family A, member 4

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in decreased expression of PDIA4 mRNA
Chlorine results in increased expression of PDIA4 mRNA

NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107

G

PDZ and LIM domain 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PDLIM1 mRNA

NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of PFKFB4 mRNA

NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634

G

post-GPI attachment to proteins 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PGAP2 mRNA

NCBI chr 1:156,591,540...156,618,116
Ensembl chr 1:156,591,615...156,618,114

G

prohibitin 1

increases expression
multiple interactions

Chlorine results in increased expression of PHB1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of PHB1 mRNA

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

G

phosphatidylinositol 4-kinase alpha

decreases expression
multiple interactions

Chlorine results in decreased expression of PI4KA mRNA
[Ozone co-treated with Chlorine] affects the expression of PI4KA mRNA

NCBI chr11:83,609,148...83,726,876
Ensembl chr11:83,609,069...83,724,080

G

phospholipase A2, group IIC

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of PLA2G2C mRNA

NCBI chr 5:150,959,365...150,981,388
Ensembl chr 5:150,959,182...150,981,377

G

placenta associated 8

increases expression

Chlorine results in increased expression of PLAC8 mRNA

NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264

G

plasminogen activator, tissue type

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PLAT mRNA

NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223

G

plectin

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PLEC mRNA

NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467

G

phospholipid phosphatase 1

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] results in decreased expression of PLPP1 mRNA
Chlorine results in decreased expression of PLPP1 mRNA

NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268

G

peripheral myelin protein 22

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PMP22 mRNA

NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714

G

pancreatic lipase

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of PNLIP mRNA

NCBI chr 1:257,774,012...257,811,656
Ensembl chr 1:257,798,581...257,811,654

G

protein phosphatase 2 catalytic subunit alpha

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PPP2CA mRNA

NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862

G

protein phosphatase 2 catalytic subunit beta

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PPP2CB mRNA

NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576

G

peroxiredoxin 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PRDX2 mRNA

NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194

G

protein arginine methyltransferase 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PRMT1 mRNA

NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345

G

proteasome 20S subunit alpha 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMA1 mRNA

NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472

G

proteasome 20S subunit alpha 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMA2 mRNA

NCBI chr17:50,554,536...50,564,923
Ensembl chr17:50,551,924...50,564,938

G

proteasome 20S subunit alpha 3

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of PSMA3L mRNA
Chlorine results in increased expression of PSMA3L mRNA

NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965

G

proteasome 20S subunit alpha 4

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMA4 mRNA

NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890

G

proteasome 20S subunit beta 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMB3 mRNA

NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521

G

proteasome 20S subunit beta 4

increases expression
multiple interactions

Chlorine results in increased expression of PSMB4 mRNA
[Ozone co-treated with Chlorine] affects the expression of PSMB4 mRNA

NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746

G

proteasome 20S subunit beta 6

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMB6 mRNA

NCBI chr10:55,239,256...55,241,586
Ensembl chr10:55,239,241...55,241,586

G

proteasome 20S subunit beta 8

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMB8 mRNA

NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283

G

proteasome 26S subunit, ATPase 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMC1 mRNA

NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123

G

proteasome 26S subunit, ATPase 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMC2 mRNA

NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185

G

proteasome 26S subunit, ATPase 4

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of PSMC4 mRNA

NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494

G

proteasome 26S subunit, ATPase 5

increases expression
multiple interactions

Chlorine results in increased expression of PSMC5 mRNA
[Ozone co-treated with Chlorine] affects the expression of PSMC5 mRNA

NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135

G

platelet-activating factor receptor

increases expression
multiple interactions

Chlorine results in increased expression of PTAFR mRNA
[Ozone co-treated with Chlorine] affects the expression of PTAFR mRNA

NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251

G

prostaglandin-endoperoxide synthase 2

increases expression

Chlorine results in increased expression of PTGS2 mRNA

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

pleiotrophin

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in increased expression of PTN mRNA
Chlorine results in increased expression of PTN mRNA

NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456

G

protein tyrosine phosphatase, non-receptor type 11

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PTPN11 mRNA

NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925

G

protein tyrosine phosphatase, non-receptor type 7

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of PTPN7 mRNA

NCBI chr13:46,570,904...46,584,048
Ensembl chr13:46,571,712...46,583,308

G

protein tyrosine phosphatase, receptor type, R

decreases expression
multiple interactions

Chlorine results in decreased expression of PTPRR mRNA
[Ozone co-treated with Chlorine] affects the expression of PTPRR mRNA

NCBI chr 7:51,662,595...51,929,605
Ensembl chr 7:51,662,595...51,929,603

G

RAB15, member RAS oncogene family

increases expression
multiple interactions

Chlorine results in increased expression of RAB15 mRNA
[Ozone co-treated with Chlorine] affects the expression of RAB15 mRNA

NCBI chr 6:95,499,584...95,524,073
Ensembl chr 6:95,499,587...95,523,942

G

RAB1A, member RAS oncogene family

increases expression
multiple interactions

Chlorine results in increased expression of RAB1A mRNA
[Ozone co-treated with Chlorine] affects the expression of RAB1A mRNA

NCBI chr14:94,422,219...94,448,799
Ensembl chr14:94,415,275...94,448,248

G

RAB2A, member RAS oncogene family

increases expression
multiple interactions

Chlorine results in increased expression of RAB2 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of RAB2 mRNA

NCBI chr 5:21,676,017...21,740,035
Ensembl chr 5:21,676,129...21,739,899

G

RAB3B, member RAS oncogene family

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of RAB3B mRNA

NCBI chr 5:123,629,562...123,697,410
Ensembl chr 5:123,644,423...123,697,401

G

RAB3D, member RAS oncogene family

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of RAB3D mRNA

NCBI chr 8:20,438,622...20,449,269
Ensembl chr 8:20,439,294...20,449,185

G

RAB4A, member RAS oncogene family

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RAB4A mRNA

NCBI chr19:51,795,613...51,822,706
Ensembl chr19:51,795,613...51,822,703

G

RAS like proto-oncogene A

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of RALA mRNA

NCBI chr17:47,092,163...47,145,192
Ensembl chr17:47,092,207...47,144,063

G

ral guanine nucleotide dissociation stimulator

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in increased expression of RALGDS mRNA
Chlorine results in increased expression of RALGDS mRNA

NCBI chr 3:11,839,686...11,880,059
Ensembl chr 3:11,839,416...11,880,059

G

RAS p21 protein activator 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RASA1 mRNA

NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854

G

regulating synaptic membrane exocytosis 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of RIMS1 mRNA

NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631

G

Ras and Rab interactor 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RIN1 mRNA

NCBI chr 1:202,355,729...202,362,731
Ensembl chr 1:202,355,890...202,362,729

G

arginyl aminopeptidase

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RNPEP mRNA

NCBI chr13:46,699,458...46,717,829
Ensembl chr13:46,699,463...46,717,998

G

ribosomal protein L10

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPL10 mRNA

NCBI chr X:152,054,562...152,056,769
Ensembl chr X:152,054,452...152,056,761

G

ribosomal protein L11

increases expression
multiple interactions

Chlorine results in increased expression of RPL11 mRNA
[Ozone co-treated with Chlorine] affects the expression of RPL11 mRNA

NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599

G

ribosomal protein L12

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPL12 mRNA

NCBI chr 3:16,264,269...16,266,645
Ensembl chr 3:16,264,251...16,266,642

G

ribosomal protein L13

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPL13 mRNA

NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014

G

ribosomal protein L21

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPL21 mRNA

NCBI chr12:8,268,641...8,272,278
Ensembl chr12:8,267,196...8,272,281
Ensembl chr 3:8,267,196...8,272,281
Ensembl chr13:8,267,196...8,272,281

G

ribosomal protein L36A like 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPL36AL mRNA

NCBI chr 6:87,654,808...87,656,202
Ensembl chr X:97,766,179...97,768,892
Ensembl chr10:97,766,179...97,768,892

G

ribosomal protein S11

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPS11 mRNA

NCBI chr 1:95,605,690...95,607,798
Ensembl chr 1:95,605,692...95,607,874

G

ribosomal protein S12

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPS12 mRNA

NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014

G

ribosomal protein S17

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPS17 mRNA

NCBI chr 1:135,295,920...135,298,506
Ensembl chr 1:135,295,919...135,298,535
Ensembl chr 8:135,295,919...135,298,535

G

ribosomal protein S19

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of RPS19 mRNA
Chlorine results in increased expression of RPS19 mRNA

NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508

G

ribosomal protein S29

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPS29 mRNA

NCBI chr 6:87,635,229...87,636,627
Ensembl chr 6:87,635,230...87,636,636

G

ribosomal protein S4, X-linked

increases expression
multiple interactions

Chlorine results in increased expression of RPS4X mRNA
[Ozone co-treated with Chlorine] results in decreased expression of RPS4X mRNA

NCBI chr X:67,298,522...67,302,965
Ensembl chr X:67,298,525...67,303,019
Ensembl chr 4:67,298,525...67,303,019

G

sphingosine-1-phosphate receptor 2

decreases expression
multiple interactions

Chlorine results in decreased expression of S1PR2 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of S1PR2 mRNA

NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574

G

sodium voltage-gated channel beta subunit 2

decreases expression
multiple interactions

Chlorine results in decreased expression of SCN2B mRNA
[Ozone co-treated with Chlorine] affects the expression of SCN2B mRNA

NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765

G

sodium voltage-gated channel alpha subunit 4

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SCN4A mRNA

NCBI chr10:91,246,936...91,296,670
Ensembl chr10:91,246,936...91,296,545

G

sterol carrier protein 2

decreases expression
multiple interactions

Chlorine results in decreased expression of SCP2 mRNA
[Ozone co-treated with Chlorine] affects the expression of SCP2 mRNA

NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287

G

secretin receptor

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SCTR mRNA

NCBI chr13:31,127,781...31,190,162
Ensembl chr13:31,127,858...31,180,189

G

selectin P

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SELP mRNA

NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845

G

serpin family B member 2

increases expression

Chlorine results in increased expression of SERPINB2 mRNA

NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408

G

serpin family B member 5

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SERPINB5 mRNA

NCBI chr13:22,985,557...23,005,756
Ensembl chr13:22,985,557...23,005,756

G

serpin family E member 1

increases expression
multiple interactions

Chlorine results in increased expression of SERPINE1 mRNA
[Ozone co-treated with Chlorine] affects the expression of SERPINE1 mRNA

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

G

surfactant protein B

affects expression

Chlorine affects the expression of SFTPB protein

NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436

G

surfactant protein D

affects expression
increases expression

Chlorine affects the expression of SFTPD protein
Chlorine results in increased expression of SFTPD protein

PMID:24582687 PMID:36690086

NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927

G

serum/glucocorticoid regulated kinase 1

decreases expression
multiple interactions

Chlorine results in decreased expression of SGK1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of SGK1 mRNA

NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283

G

sialic acid binding Ig like lectin 1

increases expression

Chlorine results in increased expression of SIGLEC1 mRNA

NCBI chr 3:118,287,988...118,307,125
Ensembl chr 3:118,287,988...118,306,850

G

signal-regulatory protein alpha

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SIRPA mRNA

NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098

G

solute carrier family 10 member 1

decreases expression
multiple interactions

Chlorine results in decreased expression of SLC10A1 mRNA
[Ozone co-treated with Chlorine] affects the expression of SLC10A1 mRNA

NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670

G

solute carrier family 14 member 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC14A2 mRNA

NCBI chr18:71,612,460...72,039,462
Ensembl chr18:71,612,460...71,792,968

G

solute carrier family 15 member 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC15A1 mRNA

NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545

G

solute carrier family 15 member 4

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SLC15A4 mRNA

NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480

G

solute carrier family 16 member 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC16A1 mRNA

NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611

G

solute carrier family 17 member 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SLC17A1 mRNA

NCBI chr17:41,219,461...41,255,199
Ensembl chr17:41,222,049...41,253,304

G

solute carrier family 18 member A1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC18A1 mRNA

NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051

G

solute carrier family 1 member 6

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of SLC1A6 mRNA

NCBI chr 7:10,841,836...10,870,424
Ensembl chr 7:10,841,837...10,870,449

G

solute carrier family 22 member 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC22A1 mRNA

NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678

G

solute carrier family 22 member 12

multiple interactions

[Chlorine co-treated with perfluoro-n-heptanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; [Chlorine co-treated with perfluoro-n-nonanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; [Chlorine co-treated with perfluorodecanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; [Chlorine co-treated with perfluorooctanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; Chlorine inhibits the reaction [SLC22A12 protein results in increased import of perfluorooctanoic acid]; Chlorine inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]

NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555

G

solute carrier family 22 member 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC22A2 mRNA

NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268

G

solute carrier family 4 member 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SLC4A2 mRNA

NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965

G

solute carrier family 6 member 12

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC6A12 mRNA

NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750

G

solute carrier family 6 member 15

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC6A15 mRNA

NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239

G

solute carrier family 6 member 9

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SLC6A9 mRNA

NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728

G

solute carrier family 7 member 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SLC7A1 mRNA

NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849

G

solute carrier family 9 member A2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC9A2 mRNA

NCBI chr 9:42,932,001...43,014,447
Ensembl chr 9:42,931,346...43,014,444

G

solute carrier organic anion transporter family, member 1a4

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] results in increased expression of SLCO1A4 mRNA
Chlorine results in decreased expression of SLCO1A4 mRNA

NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573

G

secretory leukocyte peptidase inhibitor

increases expression

Chlorine results in increased expression of SLPI mRNA

NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453

G

SMAD family member 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SMAD1 mRNA

NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651

G

survival of motor neuron 1, telomeric

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SMN1 mRNA

NCBI chr 2:31,490,018...31,501,065
Ensembl chr 2:31,490,015...31,501,060

G

synaptosome associated protein 25

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SNAP25 mRNA

NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760

G

spondin 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of SPON1 mRNA

NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226

G

structure specific recognition protein 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of SSRP1 mRNA

NCBI chr 3:70,124,371...70,134,481
Ensembl chr 3:70,118,655...70,134,482

G

somatostatin

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SST mRNA

NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173

G

somatostatin receptor 3

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of SSTR3 mRNA

NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769

G

syntaxin 1B

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of STX1B mRNA

NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280

G

syntaxin 5

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of STX5A mRNA

NCBI chr 1:205,637,401...205,653,563
Ensembl chr 1:205,637,413...205,653,563

G

syntaxin 6

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of STX6 mRNA

NCBI chr13:67,332,329...67,378,580
Ensembl chr13:67,332,314...67,378,576

G

sulfotransferase family 1B member 1

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of SULT1B1 mRNA
Chlorine results in decreased expression of SULT1B1 mRNA

NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483

G

synaptic vesicle glycoprotein 2b

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in increased expression of SV2B mRNA
Chlorine results in increased expression of SV2B mRNA

NCBI chr 1:128,978,471...129,152,479
Ensembl chr 1:128,978,473...129,152,479

G

synaptophysin

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SYP mRNA

NCBI chr X:14,849,444...14,864,553
Ensembl chr X:14,849,444...14,864,745

G

synaptotagmin 11

decreases expression
multiple interactions

Chlorine results in decreased expression of SYT11 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of SYT11 mRNA

NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964

G

synaptotagmin 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SYT2 mRNA

NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859

G

synaptotagmin 4

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SYT4 mRNA

NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332

G

tachykinin receptor 2

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of TACR2 mRNA

NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446

G

transporter 2, ATP binding cassette subfamily B member

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of TAP2 mRNA

NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407

G

thromboxane A2 receptor

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of TBXA2R mRNA

NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176

G

transferrin receptor

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of TFRC mRNA

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

transforming growth factor, beta receptor 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of TGFBR1 mRNA

NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777

G

TIMP metallopeptidase inhibitor 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of TIMP1 mRNA

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

G

thymidine kinase 1

decreases expression
multiple interactions

Chlorine results in decreased expression of TK1 mRNA
[Ozone co-treated with Chlorine] affects the expression of TK1 mRNA

NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920

G

tumor necrosis factor

increases expression

Chlorine results in increased expression of TNF protein

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 1A

increases expression

Chlorine results in increased expression of TNFRSF1A protein

NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591

G

DNA topoisomerase II alpha

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of TOP2A mRNA

NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874

G

tumor protein p53

multiple interactions
increases expression

Acetylcysteine promotes the reaction [Chlorine results in increased expression of TP53 protein modified form]

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tripeptidyl peptidase 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of TPP2 mRNA

NCBI chr 9:46,046,712...46,128,157
Ensembl chr 9:46,046,632...46,128,157

G

tubulin, alpha 1A

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of TUBA1A mRNA

NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186

G

thymidylate synthetase

decreases expression
multiple interactions

Chlorine results in decreased expression of TYMS mRNA
[Ozone co-treated with Chlorine] affects the expression of TYMS mRNA

NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536

G

unc-5 netrin receptor B

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of UNC5B mRNA

NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537

G

valosin-containing protein

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of VCP mRNA

NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571

G

von Hippel-Lindau tumor suppressor

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of VHL mRNA

NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377

G

vasoactive intestinal peptide receptor 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of VIPR1 mRNA

NCBI chr 8:121,303,739...121,339,587
Ensembl chr 8:121,310,248...121,339,585

G

vasoactive intestinal peptide receptor 2

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of VIPR2 mRNA

NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:137,001,511...137,070,597

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of YWHAE mRNA

NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of YWHAG mRNA
Chlorine results in increased expression of YWHAG mRNA

NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of YWHAH mRNA

NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

increases expression
multiple interactions

Chlorine results in increased expression of YWHAZ mRNA
[Ozone co-treated with Chlorine] results in decreased expression of YWHAZ mRNA

NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19808
role	19784
application	19627
reagent	17989
bleaching agent	3580
dichlorine	380
Path 2
Term	Annotations
CHEBI ontology	19808
subatomic particle	19806
composite particle	19806
hadron	19806
baryon	19806
nucleon	19806
atomic nucleus	19806
atom	19806
main group element atom	19756
p-block element atom	19756
p-block molecular entity	19756
halogen molecular entity	18645
chlorine molecular entity	18433
elemental chlorine	8518
diatomic chlorine	380
dichlorine	380

paths to the root