Gene: Bdkrb2 (bradykinin receptor B2) Rattus norvegicus
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Symbol: Bdkrb2
Name: bradykinin receptor B2
Description: ENCODES a protein that exhibits beta-2 adrenergic receptor binding; bradykinin receptor activity; protease binding (ortholog); INVOLVED IN acute inflammatory response to antigenic stimulus; cellular response to hypoxia; maintenance of permeability of blood-brain barrier; PARTICIPATES IN G protein mediated signaling pathway via Galphai family; G protein mediated signaling pathway via Galphaq family; kallikrein-kinin cascade pathway; ASSOCIATED WITH Asthma; asthma; Diabetes Mellitus, Experimental; FOUND IN plasma membrane; endosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3',5'-cyclic GMP; 4-amino-2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B2 bradykinin receptor; B2BKR; B2BRA; B2R; BK-2 receptor; bradykinin receptor, beta 2
Orthologs:
Homo sapiens (human) : BDKRB2 (bradykinin receptor B2)  HGNC  AGR
Mus musculus (house mouse) : Bdkrb2 (bradykinin receptor, beta 2)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Bdkrb2 (bradykinin receptor B2)
Pan paniscus (bonobo/pygmy chimpanzee) : BDKRB2 (bradykinin receptor B2)
Canis lupus familiaris (dog) : BDKRB2 (bradykinin receptor B2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bdkrb2 (bradykinin receptor B2)
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Allele / Splice: Bdkrb2m1Mcwi   Bdkrb2m2Mcwi  
Genetic Models: FHH-Bdkrb2m1Mcwi SS-Bdkrb2m2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06129,399,468 - 129,429,676 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06138,615,812 - 138,622,272 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46129,744,781 - 129,748,851 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16129,748,527 - 129,752,598 (+)NCBI
Celera6122,039,524 - 122,069,422 (+)NCBICelera
Cytogenetic Map6q32NCBI
RH 3.4 Map6815.41RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Bdkrb2
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2201
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-12-05
Status: ACTIVE