Gene: Casr (calcium-sensing receptor) Rattus norvegicus
Symbol: Casr
Name: calcium-sensing receptor
Description: ENCODES a protein that exhibits calcium ion binding; drug binding; G-protein coupled receptor activity; INVOLVED IN adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; apoptotic process; branching morphogenesis of an epithelial tube; PARTICIPATES IN calcium signaling pathway via the calcium-sensing receptor; G protein mediated signaling pathway via Galphai family; G protein mediated signaling pathway via Galphaq family; ASSOCIATED WITH Albuminuria; Anoxia; Atherosclerosis; FOUND IN apical plasma membrane; axon; axon terminus; INTERACTS WITH 6-propyl-2-thiouracil; aluminium atom; aluminium(0)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism); Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); extracellular calcium-sensing receptor; parathyroid Cell calcium-sensing receptor; PCaR1
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01167,188,630 - 67,258,721+NCBI
Rat Cytogenetic Map11q22 NCBI
RGSC Genome Assembly v5.01170,278,784 - 70,352,137+NCBI
RGSC Genome Assembly v3.41166,084,169 - 66,153,292-NCBI
Rat Celera Assembly1163,705,377 - 63,774,820+NCBI
Genome Assembly 3.11166,141,757 - 66,210,881-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Casr
Entrez Gene
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RGD Object Information
RGD ID: 2277
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-02-02
Status: ACTIVE