Gene: Casr (calcium-sensing receptor) Rattus norvegicus
Symbol: Casr
Name: calcium-sensing receptor
Description: ENCODES a protein that exhibits calcium ion binding; drug binding; G-protein coupled receptor activity; INVOLVED IN adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; apoptotic process; branching morphogenesis of an epithelial tube; PARTICIPATES IN calcium signaling pathway via the calcium-sensing receptor; G protein mediated signaling pathway via Galphai family; G protein mediated signaling pathway via Galphaq family; ASSOCIATED WITH Albuminuria; Anoxia; Atherosclerosis; FOUND IN apical plasma membrane; axon; axon terminus; INTERACTS WITH 6-propyl-2-thiouracil; aluminium atom; aluminium(0)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism); Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); extracellular calcium-sensing receptor; parathyroid Cell calcium-sensing receptor; PCaR1
Allele / Splice: Casrem1Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01167,188,204 - 67,262,261 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01170,278,784 - 70,352,137 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41166,084,169 - 66,153,292 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11166,141,757 - 66,210,881 (-)NCBI
Celera1163,705,377 - 63,774,888 (+)NCBI
Cytogenetic Map11q22NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Casr
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 2277
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-10-04
Status: ACTIVE