Nr3c2 (nuclear receptor subfamily 3, group C, member 2)

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Keyword

Gene: Nr3c2 (nuclear receptor subfamily 3, group C, member 2) Rattus norvegicus

Symbol:

Nr3c2

Name:

nuclear receptor subfamily 3, group C, member 2

Description:

ENCODES a protein that exhibits double-stranded DNA binding; hormone binding; mineralocorticoid receptor activity; INVOLVED IN mineralocorticoid receptor signaling pathway; regulation of cell proliferation; cellular sodium ion homeostasis (ortholog); PARTICIPATES IN aldosterone signaling pathway; ASSOCIATED WITH Hypertension, Early-Onset, Autosomal Dominant, with Severe Exacerbation in Pregnancy (ortholog); Pseudohypoaldosteronism (ortholog); FOUND IN cytoplasm; nucleus; INTERACTS WITH (S)-nicotine; 11-deoxycorticosterone; 2,3,7,8-tetrachlorodibenzodioxine

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

MCR; mineralocorticoid receptor; Mineralocorticoid receptor (aldosterone receptor); Mlr; MR; nuclear receptor subfamily 3, group C, member 2

Orthologs:

Homo sapiens : NR3C2 (nuclear receptor subfamily 3, group C, member 2) HGNC
Mus musculus : Nr3c2 (nuclear receptor subfamily 3, group C, member 2) MGI

Is Marker For:

QTLs: Salc2 Gmadr1 Bw28

Latest Assembly:

RGSC Genome Assembly v3.4

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	19	q11		NCBI
RGSC Genome Assembly v5.0	19	45,287,442 - 45,639,834	-	NCBI
RGSC Genome Assembly v3.4	19	32,527,752 - 32,875,369	-	NCBI
Rat Celera Assembly	19	30,192,512 - 30,534,995	-	NCBI
Genome Assembly 3.1	19	32,532,632 - 32,880,250	-	NCBI