Gene: Nr3c2 (nuclear receptor subfamily 3, group C, member 2) Rattus norvegicus
Symbol: Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Description: ENCODES a protein that exhibits double-stranded DNA binding; hormone binding; mineralocorticoid receptor activity; INVOLVED IN mineralocorticoid receptor signaling pathway; regulation of cell proliferation; cellular sodium ion homeostasis (ortholog); PARTICIPATES IN aldosterone signaling pathway; ASSOCIATED WITH Hypertension, Early-Onset, Autosomal Dominant, with Severe Exacerbation in Pregnancy (ortholog); Melanoma (ortholog); Pseudohypoaldosteronism (ortholog); FOUND IN cytoplasm; nucleus; cell (ortholog); INTERACTS WITH (S)-nicotine; 11-deoxycorticosterone; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MCR; mineralocorticoid receptor; Mineralocorticoid receptor (aldosterone receptor); Mlr; MR
Orthologs:
Is Marker For: QTLs:   Salc2   Gmadr1   Bw28  
Latest Assembly: RGSC Genome Assembly v3.4
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.01934,408,275 - 34,761,003-NCBI
Rat Cytogenetic Map19q11 NCBI
RGSC Genome Assembly v5.01945,287,442 - 45,639,834-NCBI
RGSC Genome Assembly v3.41932,527,752 - 32,875,369-NCBI
Rat Celera Assembly1930,192,512 - 30,534,995-NCBI
Genome Assembly 3.11932,532,632 - 32,880,250-NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nr3c2
Entrez Gene
Ensembl Gene
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NCBI Map Viewer
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RGD Object Information
RGD ID: 3094
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2014-10-14
Status: ACTIVE