Gene: Nr3c2 (nuclear receptor subfamily 3, group C, member 2) Rattus norvegicus
Symbol: Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Description: ENCODES a protein that exhibits double-stranded DNA binding; hormone binding; mineralocorticoid receptor activity; INVOLVED IN mineralocorticoid receptor signaling pathway; regulation of cell proliferation; cellular sodium ion homeostasis (ortholog); PARTICIPATES IN aldosterone signaling pathway; amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; ASSOCIATED WITH Hypertension, Early-Onset, Autosomal Dominant, with Severe Exacerbation in Pregnancy (ortholog); Pseudohypoaldosteronism (ortholog); FOUND IN cytoplasm; nucleus; receptor complex (ortholog); INTERACTS WITH 11-deoxycorticosterone; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MCR; mineralocorticoid receptor; Mineralocorticoid receptor (aldosterone receptor); Mlr; MR
Orthologs:
Is Marker For: QTLs:   Salc2   Gmadr1   Bw28  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01934,408,275 - 34,761,003 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01945,287,442 - 45,639,834 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41932,527,752 - 32,875,369 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11932,532,632 - 32,880,250 (-)NCBI
Celera1930,192,512 - 30,534,995 (-)NCBI
Cytogenetic Map19q11NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nr3c2
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3094
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-07-05
Status: ACTIVE