Gene: Gnai2 (G protein subunit alpha i2) Rattus norvegicus
Symbol: Gnai2
Name: G protein subunit alpha i2
Description: ENCODES a protein that exhibits G-protein beta/gamma-subunit complex binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN activation of MAPKK activity; adenosine receptor signaling pathway; G-protein coupled receptor signaling pathway; PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family; angiotensin II signaling pathway via AT2 receptor; dopamine signaling pathway via D2 family of receptors; ASSOCIATED WITH ACTH-Secreting Pituitary Adenoma (ortholog); Adrenal Cortex Neoplasms (ortholog); Atrioventricular Block (ortholog); FOUND IN cytosol; membrane; membrane raft; INTERACTS WITH (+)-alpha-tocopherol; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: adenylate cyclase-inhibiting G alpha protein; G alpha inhibitory type 2 (a); G alpha inhibitory type 2 (b); Galphai2; GTP-binding protein (G-alpha-i2); guanine nucleotide binding protein (G protein), alpha inhibiting 2; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2; guanine nucleotide binding protein, alpha inhibiting 2; guanine nucleotide-binding protein G(i) subunit alpha-2; guanine nucleotide-binding protein G(i), alpha-2 subunit
Homo sapiens (human) : GNAI2 (G protein subunit alpha i2)  HGNC  AGR
Mus musculus (house mouse) : Gnai2 (guanine nucleotide binding protein (G protein), alpha inhibiting 2)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Gnai2 (G protein subunit alpha i2)
Pan paniscus (bonobo/pygmy chimpanzee) : GNAI2 (G protein subunit alpha i2)
Canis lupus familiaris (dog) : GNAI2 (G protein subunit alpha i2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnai2 (G protein subunit alpha i2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.08116,370,730 - 116,391,337 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08115,726,562 - 115,746,754 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48112,861,952 - 112,882,647 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18112,881,416 - 112,902,054 (-)NCBI
Celera8107,594,933 - 107,615,332 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gnai2
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620243
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE