Gene: Tap2 (transporter 2, ATP binding cassette subfamily B member) Rattus norvegicus
Symbol: Tap2
Name: transporter 2, ATP binding cassette subfamily B member
Description: ENCODES a protein that exhibits ADP binding; ATP binding; MHC class I protein binding; INVOLVED IN antigen processing and presentation of endogenous peptide antigen via MHC class I; peptide transport; positive regulation of antigen processing and presentation of peptide antigen via MHC class I; PARTICIPATES IN antigen processing and presentation pathway; phagocytosis pathway; primary immunodeficiency disease pathway; ASSOCIATED WITH Alzheimer Disease (ortholog); Arthritis, Reactive (ortholog); Arthritis, Rheumatoid (ortholog); FOUND IN intracellular membrane-bounded organelle; MHC class I peptide loading complex; TAP complex; INTERACTS WITH 4,4'-diaminodiphenylmethane; 4-(ethoxymethylene)-2-phenyloxazol-5-one; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Abcb3; antigen peptide transporter 2; APT2; ATP-binding cassette sub-family B member 3; Cim; MGC108646; Transporter 2 ABC (ATP binding cassette); transporter 2 ATP-binding cassette sub-family B; Transporter 2, ABC (ATP binding cassette); transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0203,995,544 - 4,009,587 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0206,075,031 - 6,089,429 (+)NCBIRnor5.0rn5Rnor5.0
Rnor_5.0207,259,226 - 7,273,268 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4204,770,446 - 4,784,488 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,770,672 - 4,784,715 (-)NCBI
Celera206,237,501 - 6,251,447 (-)NCBI
Cytogenetic Map20p12NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Tap2
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 3818
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-10-11
Status: ACTIVE