Gene: Tap2 (transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)) Rattus norvegicus
Symbol: Tap2
Name: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Description: ENCODES a protein that exhibits ADP binding; ATP binding; MHC class I protein binding; INVOLVED IN antigen processing and presentation of endogenous peptide antigen via MHC class I; peptide transport; positive regulation of antigen processing and presentation of peptide antigen via MHC class I; PARTICIPATES IN antigen processing and presentation pathway; phagocytosis pathway; primary immunodeficiency disease pathway; ASSOCIATED WITH Alzheimer Disease (ortholog); Arthritis, Reactive (ortholog); Arthritis, Rheumatoid (ortholog); FOUND IN intracellular membrane-bounded organelle; MHC class I peptide loading complex; TAP complex; INTERACTS WITH 4-(ethoxymethylene)-2-phenyloxazol-5-one; ammonium chloride; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Abcb3; antigen peptide transporter 2; APT2; ATP-binding cassette sub-family B member 3; Cim; MGC108646; Transporter 2 ABC (ATP binding cassette); transporter 2 ATP-binding cassette sub-family B; Transporter 2, ABC (ATP binding cassette)
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0203,995,544 - 4,009,587+NCBI
Rat Cytogenetic Map20p12 NCBI
RGSC Genome Assembly v5.0207,259,226 - 7,273,268-NCBI
RGSC Genome Assembly v5.0206,075,031 - 6,089,429+NCBI
RGSC Genome Assembly v3.4204,770,446 - 4,784,488-NCBI
Rat Celera Assembly206,237,501 - 6,251,447-NCBI
Genome Assembly 3.1204,770,672 - 4,784,715-NCBI
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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Tap2
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 3818
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-10-01
Status: ACTIVE