Gene: Ager (advanced glycosylation end product-specific receptor) Rattus norvegicus
Symbol: Ager
Name: advanced glycosylation end product-specific receptor
Description: ENCODES a protein that exhibits advanced glycation end-product receptor activity; high mobility group box 1 binding; S100 protein binding; INVOLVED IN brain development; calcium ion homeostasis; cellular response to drug; PARTICIPATES IN Ras mediated signaling pathway; receptor for advanced glycation end-products signaling pathway; ASSOCIATED WITH Acute Lung Injury; Albuminuria; Alzheimer Disease; FOUND IN axon; basal plasma membrane; cell surface; INTERACTS WITH 3,4-dihydroxybenzaldehyde; aldehydo-D-glucose; all-trans-retinol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: advanced glycosylation end product-specific receptor variant 2; advanced glycosylation end product-specific receptor variant 3; advanced glycosylation end product-specific receptor variant 4; advanced glycosylation end product-specific receptor variant 5; RAGE; receptor for advanced glycosylation end products
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0204,363,152 - 4,366,079 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0206,442,508 - 6,445,435 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,250,613 - 4,253,540 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,250,839 - 4,253,767 (-)NCBI
Celera203,879,126 - 3,882,053 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ager
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69258
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2018-01-02
Status: ACTIVE