GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ager | increases cleavage | ISO | Ager (Mus musculus) | 6480464 | CTD | Pyruvaldehyde results in increased cleavage of AGER protein | PMID:26723916 PMID:29148590 | Ager | increases expression | ISO | AGER (Homo sapiens) | 6480464 | CTD | Pyruvaldehyde results in increased expression of AGER mRNA | PMID:30447388 | Ager | increases expression | ISO | Ager (Mus musculus) | 6480464 | CTD | Pyruvaldehyde results in increased expression of AGER mRNA; Pyruvaldehyde results in increased expression of AGER protein | PMID:22101032 PMID:34656697 | Ager | multiple interactions | ISO | Ager (Mus musculus) | 6480464 | CTD | bergenin inhibits the reaction [Pyruvaldehyde results in increased cleavage of AGER protein]; epigallocatechin gallate inhibits the reaction [Pyruvaldehyde results in increased expression of AGER protein]; honokiol affects the reaction [Pyruvaldehyde results in increased cleavage of AGER protein]; pimagedine inhibits the reaction [Pyruvaldehyde results in increased cleavage of AGER protein] | PMID:22101032 PMID:26723916 PMID:29148590 | | ||||||||||||||||||||||
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