AGER (advanced glycosylation end-product specific receptor) - Rat Genome Database

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Gene: AGER (advanced glycosylation end-product specific receptor) Homo sapiens
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Symbol: AGER
Name: advanced glycosylation end-product specific receptor
RGD ID: 737312
HGNC Page HGNC:320
Description: Enables several functions, including S100 protein binding activity; amyloid-beta binding activity; and identical protein binding activity. Involved in several processes, including glial cell activation; modulation of chemical synaptic transmission; and positive regulation of intracellular signal transduction. Located in apical plasma membrane; cell junction; and fibrillar center. Implicated in several diseases, including autoimmune disease (multiple); cardiovascular system disease (multiple); cystic fibrosis; kidney failure (multiple); and lupus nephritis. Biomarker of several diseases, including artery disease (multiple); chronic kidney disease (multiple); congestive heart failure (multiple); diabetic retinopathy (multiple); and lung disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: advanced glycosylation end product-specific receptor; MGC22357; RAGE; RAGE isoform delta; RAGE isoform NtRAGE-delta; RAGE isoform sRAGE-delta; receptor for advanced glycation end-products; receptor for advanced glycation end-products variant 20; receptor for advanced glycosylation end products; receptor for advanced glycosylation end-products; SCARJ1; sRAGE
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,180,969 - 32,184,253 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,180,968 - 32,184,322 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,148,746 - 32,152,030 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,256,724 - 32,260,001 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,256,723 - 32,260,001NCBI
Celera633,715,793 - 33,719,070 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef631,902,943 - 31,906,297 (-)NCBIHuRef
CHM1_1632,151,229 - 32,154,583 (-)NCBICHM1_1
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Coronary Syndrome  (IEP)
acute kidney failure  (IDA)
Acute Lung Injury  (ISO)
adult respiratory distress syndrome  (ISO)
Albuminuria  (IEP,ISO)
Alzheimer's disease  (IDA,IEP,ISO)
Aortic Calcification  (ISO)
aortic disease  (ISO,ISS)
aspergillosis  (IAGP)
asthma  (EXP,IEP,ISO)
atherosclerosis  (EXP,IEP,ISO)
atrial fibrillation  (IEP)
bacterial pneumonia  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Breast Neoplasms  (IAGP,IEP)
Cardiac Fibrosis  (ISO)
cardiovascular system disease  (IAGP,ISO)
carotid artery disease  (IEP,ISO)
Carotid Artery Injuries  (ISO)
cerebral infarction  (IEP)
chorioamnionitis  (IEP)
Chronic Allograft Dysfunction  (ISO)
chronic kidney disease  (IAGP,IDA,IEP)
chronic obstructive pulmonary disease  (IEP)
clear cell renal cell carcinoma  (IEP)
colorectal carcinoma  (ISS)
congestive heart failure  (IEP)
contact dermatitis  (ISO)
Cor pulmonale  (IEP)
coronary artery disease  (IAGP,IEP)
Coronary Disease  (IEP)
cystic fibrosis  (IAGP,IEP)
diabetes mellitus  (IEP)
diabetic angiopathy  (EXP)
Diabetic Cardiomyopathies  (ISO)
diabetic encephalopathy  (ISO)
Diabetic Foot  (IEP)
Diabetic Nephropathies  (IAGP,IEP,ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (IAGP,IEA,IEP,ISO)
end stage renal disease  (IEP)
Epidermal Hyperplasia  (ISO)
Experimental Autoimmune Myocarditis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Fibrosis  (ISO)
gastrointestinal system disease  (ISO)
genetic disease  (IAGP)
glomerulosclerosis  (ISO)
Hyperalgesia  (EXP,ISO)
hyperglycemia  (EXP)
Hyperoxia  (ISO)
hypertension  (EXP,ISO)
Hypertrophy  (EXP)
impotence  (ISO)
Inflammation  (EXP,IEP)
inflammatory bowel disease  (IEP)
intracranial aneurysm  (ISO)
invasive aspergillosis  (ISO)
invasive ductal carcinoma  (IEP)
Kawasaki disease  (IEP)
kidney disease  (ISO)
Left Ventricular Hypertrophy  (IEP)
leishmaniasis  (ISO)
Lewy body dementia  (EXP)
liver cirrhosis  (IEP)
Liver Reperfusion Injury  (ISO)
Lung Injury  (ISO)
Lung Neoplasms  (IEA)
lung non-small cell carcinoma  (IEP)
lupus nephritis  (IAGP)
melanoma  (IMP)
middle cerebral artery infarction  (EXP,ISO)
mild cognitive impairment  (IDA)
morbid obesity  (IDA)
multiple sclerosis  (IAGP)
myocardial infarction  (IAGP,ISO)
Myocardial Ischemia  (IAGP)
Myocardial Reperfusion Injury  (ISO)
Neointima  (IDA)
neovascular inflammatory vitreoretinopathy  (IEP)
Neuralgia  (EXP)
obesity  (IEP,ISO)
occupational asthma  (EXP)
optic nerve disease  (IEP)
osteoarthritis  (EXP,ISO)
osteoporosis  (ISO)
ovarian carcinoma  (EXP)
pancreas disease  (EXP)
pancreatic cancer  (IEP)
periodontitis  (IEP,ISO)
Peripheral Nerve Injuries  (EXP)
Peritoneal Fibrosis  (ISO)
polycystic kidney disease  (ISO)
proliferative diabetic retinopathy  (IEP)
prostate cancer  (IEP)
proteasome-associated autoinflammatory syndrome 1  (IAGP)
proteinuria  (IAGP)
psoriasis  (IAGP)
pulmonary emphysema  (EXP)
pulmonary fibrosis  (IEP,ISO)
pulmonary hypertension  (IEP)
renal fibrosis  (IEP,ISO)
rheumatoid arthritis  (EXP,IEP)
rosacea  (ISO)
schistosomiasis  (ISO)
schizophrenia  (IAGP)
schizotypal personality disorder  (IAGP)
Sepsis  (ISO)
Skin Neoplasms  (ISO)
Spinal Cord Injuries  (ISO)
Stroke  (IAGP,ISO)
Subarachnoid Hemorrhage  (ISO)
systemic lupus erythematosus  (IAGP)
systemic scleroderma  (IEP,ISO)
Takayasu's arteritis  (IEP)
thromboangiitis obliterans  (ISO)
Tongue Neoplasms  (ISO)
toxic shock syndrome  (ISO)
transient cerebral ischemia  (ISO)
tuberculosis  (ISO)
type 1 diabetes mellitus  (IAGP,IEP,ISO)
type 2 diabetes mellitus  (IAGP,ISO)
uremia  (ISO)
ureteral obstruction  (ISO)
Vascular Calcification  (IEP,ISO)
vascular skin disease  (IAGP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-Nornicotine  (EXP)
(-)-anisomycin  (EXP)
(-)-cotinine  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,2,2-tetramine  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
3,4-dihydroxybenzaldehyde  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-phenylprop-2-enal  (ISO)
6-propyl-2-thiouracil  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
acteoside  (EXP)
agomelatine  (ISO)
aldehydo-D-glucose  (EXP,ISO)
aldehydo-D-ribose  (ISO)
all-trans-retinol  (ISO)
allyl isothiocyanate  (ISO)
alpha-D-galactose  (ISO)
aminoguanidine  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
ampicillin  (ISO)
anthocyanin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
aristolochic acid A  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
azathioprine  (ISO)
benazepril  (ISO)
benzo[a]pyrene  (EXP)
berberine  (ISO)
Bergenin  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
Bisphenol A diglycidyl ether  (ISO)
bleomycin A2  (ISO)
bortezomib  (ISO)
butanal  (EXP)
C60 fullerene  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
calycosin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carnosine  (ISO)
chlorohydrocarbon  (ISO)
cholesterol  (EXP)
cisplatin  (EXP)
curcumin  (ISO)
D-glucose  (EXP,ISO)
D-ribofuranose  (ISO)
dapagliflozin  (ISO)
dichlorine  (ISO)
diclofenac  (EXP,ISO)
dicloxacillin  (ISO)
Dimerumic acid  (ISO)
dimethyl fumarate  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
estriol  (EXP)
ethanol  (ISO)
Ethyl pyruvate  (ISO)
febuxostat  (ISO)
flutamide  (EXP,ISO)
fructose  (ISO)
fulvestrant  (EXP)
furan  (ISO)
galactose  (ISO)
galanthamine  (ISO)
gallic acid  (ISO)
genistein  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
glucose  (EXP,ISO)
glyburide  (ISO)
graphene oxide  (ISO)
hesperetin  (ISO)
Honokiol  (ISO)
hydrogen peroxide  (ISO)
indoprofen  (EXP)
lead diacetate  (ISO)
leflunomide  (ISO)
linoleic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
losartan  (ISO)
luteolin  (EXP)
LY294002  (ISO)
lycopene  (EXP)
mangiferin  (ISO)
mebendazole  (EXP)
melatonin  (ISO)
mesalamine  (ISO)
metformin  (ISO)
methimazole  (ISO)
methylglyoxal  (EXP,ISO)
methylmercury chloride  (ISO)
naphthalene  (ISO)
nitrofen  (ISO)
oleanolic acid  (EXP)
oxidopamine  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentanal  (EXP)
pentetrazol  (ISO)
perfluorohexanesulfonic acid  (ISO)
permethrin  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
pioglitazone  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
procyanidin B2  (ISO)
procyanidin B3  (ISO)
propanal  (EXP)
protein kinase inhibitor  (ISO)
Pyridostigmine bromide  (ISO)
quercetin  (EXP)
reactive oxygen species  (ISO)
resveratrol  (EXP)
rotenone  (EXP)
rutin  (EXP)
SB 203580  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (EXP)
sinapic acid  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
streptozocin  (ISO)
sulfadimethoxine  (ISO)
sulfasalazine  (ISO)
testosterone  (EXP)
thioacetamide  (ISO)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (EXP,ISO)
trichloroethene  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (EXP)
troglitazone  (ISO)
vinclozolin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
astrocyte activation  (IGI)
astrocyte development  (IEA,ISO)
cell adhesion  (IEA)
cell surface receptor signaling pathway  (TAS)
cell surface receptor signaling pathway via JAK-STAT  (ISO)
cellular response to amyloid-beta  (IEA,ISS)
cellular response to fatty acid  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to xenobiotic stimulus  (ISO)
glucose mediated signaling pathway  (IDA)
glycoprotein metabolic process  (ISO)
induction of positive chemotaxis  (IEA,ISO)
inflammatory response  (IEA,ISO,TAS)
learning or memory  (IGI)
lung development  (ISO)
microglial cell activation  (IEA,IGI,ISS)
negative regulation of blood circulation  (IEA,ISS)
negative regulation of cell adhesion  (ISO)
negative regulation of collagen biosynthetic process  (ISO)
negative regulation of endothelial cell migration  (ISO)
negative regulation of endothelial cell proliferation  (ISO)
negative regulation of interleukin-10 production  (IDA)
negative regulation of long-term synaptic depression  (IGI)
negative regulation of long-term synaptic potentiation  (IEA,IGI,ISS)
negative regulation of osteoblast proliferation  (ISO)
negative regulation of protein phosphorylation  (ISO)
neuron projection development  (IGI,ISO)
positive regulation of activated T cell proliferation  (IMP)
positive regulation of apoptotic process  (ISO)
positive regulation of autophagy  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cellular process  (ISO)
positive regulation of chemokine production  (IEA,ISS)
positive regulation of dendritic cell differentiation  (IMP)
positive regulation of endothelial cell apoptotic process  (ISO)
positive regulation of endothelin production  (IEA,ISS)
positive regulation of epithelial to mesenchymal transition  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IGI)
positive regulation of fibroblast migration  (ISO)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of heterotypic cell-cell adhesion  (IGI)
positive regulation of interleukin-1 beta production  (IEA,ISS)
positive regulation of interleukin-12 production  (IMP)
positive regulation of interleukin-6 production  (IEA,ISS)
positive regulation of JNK cascade  (IGI)
positive regulation of monocyte chemotactic protein-1 production  (IEA,ISO)
positive regulation of monocyte extravasation  (IMP)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of non-canonical NF-kappaB signal transduction  (IGI)
positive regulation of p38MAPK cascade  (IGI)
positive regulation of phagocytosis, engulfment  (ISO)
positive regulation of potassium ion transmembrane transporter activity  (ISO)
positive regulation of protein phosphorylation  (IGI,ISO)
positive regulation of reactive oxygen species metabolic process  (ISO)
positive regulation of smooth muscle cell migration  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of tumor necrosis factor production  (IEA,ISS)
positive regulation of type B pancreatic cell apoptotic process  (ISO)
protein localization to membrane  (IEA,ISO)
regulation of CD4-positive, alpha-beta T cell activation  (IDA)
regulation of inflammatory response  (IBA,IEA)
regulation of long-term synaptic potentiation  (IEA,ISS)
regulation of non-canonical NF-kappaB signal transduction  (NAS)
regulation of p38MAPK cascade  (IBA,IEA,ISS)
regulation of spontaneous synaptic transmission  (IGI)
regulation of synaptic plasticity  (TAS)
regulation of T cell mediated cytotoxicity  (IDA)
response to activity  (ISO)
response to amyloid-beta  (IEA,ISS,TAS)
response to fructose  (ISO)
response to genistein  (ISO)
response to hyperoxia  (ISO)
response to hypoxia  (IEA,ISO)
response to methylglyoxal  (ISO)
response to selenite ion  (ISO)
response to vitamin A  (ISO)
response to wounding  (TAS)
transcytosis  (IEA,ISS)
transdifferentiation  (ISO)
transport across blood-brain barrier  (IDA,NAS)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The relationship between receptor for advanced glycation end products expression and the severity of periodontal disease in the gingiva of diabetic and non diabetic periodontitis patients. Abbass MM, etal., Arch Oral Biol. 2012 Jul 12.
2. Proteomic analysis of lung tissues from patients with pulmonary arterial hypertension. Abdul-Salam VB, etal., Circulation. 2010 Nov 16;122(20):2058-67. doi: 10.1161/CIRCULATIONAHA.110.972745. Epub 2010 Nov 1.
3. Regulation of human melanoma growth and metastasis by AGE-AGE receptor interactions. Abe R, etal., J Invest Dermatol. 2004 Feb;122(2):461-7.
4. Identification of a functional interaction of HMGB1 with Receptor for Advanced Glycation End-products in a model of neuropathic pain. Allette YM, etal., Brain Behav Immun. 2014 Jul 8. pii: S0889-1591(14)00364-X. doi: 10.1016/j.bbi.2014.06.199.
5. Increased expression of advanced glycation end-products and their receptor, and activation of nuclear factor kappa-B in lacrimal glands of diabetic rats. Alves M, etal., Diabetologia. 2005 Dec;48(12):2675-81. Epub 2005 Nov 8.
6. Association analysis of nine candidate gene polymorphisms in Indian patients with type 2 diabetic retinopathy. Balasubbu S, etal., BMC Med Genet. 2010 Nov 10;11:158. doi: 10.1186/1471-2350-11-158.
7. Polymorphisms in the TNF-alpha and IL10 gene promoters and risk of arsenic-induced skin lesions and other nondermatological health effects. Banerjee N, etal., Toxicol Sci. 2011 May;121(1):132-9. doi: 10.1093/toxsci/kfr046. Epub 2011 Feb 25.
8. -374 T/A RAGE Polymorphism Is Associated with Chronic Kidney Disease Progression in Subjects Affected by Nephrocardiovascular Disease. Baragetti I, etal., PLoS One. 2013 Apr 4;8(4):e60089. doi: 10.1371/journal.pone.0060089. Print 2013.
9. Down-regulation of the receptor for advanced glycation end-products (RAGE) supports non-small cell lung carcinoma. Bartling B, etal., Carcinogenesis. 2005 Feb;26(2):293-301. Epub 2004 Nov 11.
10. The genetic association database. Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
11. Predicting diabetic nephropathy using a multifactorial genetic model. Blech I, etal., PLoS One. 2011 Apr 14;6(4):e18743. doi: 10.1371/journal.pone.0018743.
12. The soluble form of the receptor of advanced glycation endproducts increases after bariatric surgery in morbid obesity. Brix JM, etal., Int J Obes (Lond). 2012 Nov;36(11):1412-7. doi: 10.1038/ijo.2012.107. Epub 2012 Jul 17.
13. Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury. Bucciarelli LG, etal., Circulation. 2006 Mar 7;113(9):1226-34. Epub 2006 Feb 27.
14. RAGE and modulation of ischemic injury in the diabetic myocardium. Bucciarelli LG, etal., Diabetes. 2008 Jul;57(7):1941-51. Epub 2008 Apr 16.
15. Association of increased S100B, S100A6 and S100P in serum levels with acute coronary syndrome and also with the severity of myocardial infarction in cardiac tissue of rat models with ischemia-reperfusion injury. Cai XY, etal., Atherosclerosis. 2011 Aug;217(2):536-42. Epub 2011 May 27.
16. Arterial calcification is driven by RAGE in Enpp1-/- mice. Cecil DL and Terkeltaub RA, J Vasc Res. 2011;48(3):227-35. doi: 10.1159/000318805. Epub 2010 Nov 23.
17. Glycated matrix up-regulates inflammatory signaling similarly to Porphyromonas gingivalis lipopolysaccharide. Chang PC, etal., J Periodontal Res. 2013 Apr;48(2):184-93. doi: 10.1111/j.1600-0765.2012.01519.x. Epub 2012 Aug 26.
18. Puerarin enhances superoxide dismutase activity and inhibits RAGE and VEGF expression in retinas of STZ-induced early diabetic rats. Chen F, etal., Asian Pac J Trop Med. 2012 Nov;5(11):891-6. doi: 10.1016/S1995-7645(12)60166-7.
19. Ancestral haplotype 8.1 and lung disease severity in European cystic fibrosis patients. Corvol H, etal., J Cyst Fibros. 2012 Jan;11(1):63-7. Epub 2011 Oct 10.
20. APPswe/Abeta regulation of osteoclast activation and RAGE expression in an age-dependent manner. Cui S, etal., J Bone Miner Res. 2011 May;26(5):1084-98. doi: 10.1002/jbmr.299.
21. Genetically-determined hyperfunction of the S100B/RAGE axis is a risk factor for aspergillosis in stem cell transplant recipients. Cunha C, etal., PLoS One. 2011;6(11):e27962. doi: 10.1371/journal.pone.0027962. Epub 2011 Nov 17.
22. Schistosoma mansoni infection causes oxidative stress and alters receptor for advanced glycation endproduct (RAGE) and tau levels in multiple organs in mice. de Oliveira RB, etal., Int J Parasitol. 2013 Apr;43(5):371-9. doi: 10.1016/j.ijpara.2012.12.006. Epub 2013 Jan 29.
23. Inhibition of the interaction of AGE-RAGE prevents hyperglycemia-induced fibrosis of the peritoneal membrane. De Vriese AS, etal., J Am Soc Nephrol. 2003 Aug;14(8):2109-18.
24. Myofibroblast transdifferentiation of mesothelial cells is mediated by RAGE and contributes to peritoneal fibrosis in uraemia. De Vriese AS, etal., Nephrol Dial Transplant. 2006 Sep;21(9):2549-55. Epub 2006 Jun 6.
25. RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain. Deane R, etal., Nat Med 2003 Jul;9(7):907-13.
26. The -374A allele of the receptor for advanced glycation end products gene is associated with a decreased risk of ischemic heart disease in African-Brazilians with type 2 diabetes. dos Santos KG, etal., Mol Genet Metab. 2005 Jun;85(2):149-56. Epub 2005 Mar 24.
27. Levels of soluble advanced glycation end product-receptors and other soluble serum markers as indicators of diabetic neuropathy in the foot. El-Mesallamy HO, etal., J Investig Med. 2011 Dec;59(8):1233-8.
28. Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease. Ferhani N, etal., Am J Respir Crit Care Med. 2010 May 1;181(9):917-27. Epub 2010 Feb 4.
29. Determinants of thromboxane biosynthesis in rheumatoid arthritis: Role of RAGE and oxidant stress. Ferrante E, etal., Free Radic Biol Med. 2010 Sep 1;49(5):857-64. doi: 10.1016/j.freeradbiomed.2010.06.009. Epub 2010 Jun 10.
30. Association of polymorphisms in the RAGE gene with serum CRP levels and coronary artery disease in the Chinese Han population. Gao J, etal., J Hum Genet. 2010 Oct;55(10):668-75. Epub 2010 Jul 29.
31. Expression of HMGB1 and RAGE in rat and human brains after traumatic brain injury. Gao TL, etal., J Trauma Acute Care Surg. 2012 Mar;72(3):643-9. doi: 10.1097/TA.0b013e31823c54a6.
32. RAGE-mediated interstitial fibrosis in neonatal obstructive nephropathy is independent of NF-kappaB activation. Gasparitsch M, etal., Kidney Int. 2013 May 15. doi: 10.1038/ki.2013.171.
33. Increased tau phosphorylation and receptor for advanced glycation endproducts (RAGE) in the brain of mice infected with Leishmania amazonensis. Gasparotto J, etal., Brain Behav Immun. 2014 Jul 8. pii: S0889-1591(14)00389-4. doi: 10.1016/j.bbi.2014.06.204.
34. RAGE signaling sustains inflammation and promotes tumor development. Gebhardt C, etal., J Exp Med. 2008 Feb 18;205(2):275-85. doi: 10.1084/jem.20070679. Epub 2008 Jan 21.
35. The possible role of esRAGE and sRAGE in the natural history of diabetic nephropathy in childhood. Giannini C, etal., Pediatr Nephrol. 2012 Feb;27(2):269-75. doi: 10.1007/s00467-011-1988-5. Epub 2011 Aug 26.
36. The pleiotropic actions of rosuvastatin confer renal benefits in the diabetic Apo-E knockout mouse. Giunti S, etal., Am J Physiol Renal Physiol. 2010 Sep;299(3):F528-35. doi: 10.1152/ajprenal.00127.2010. Epub 2010 Jun 16.
37. The - 429 T/C and - 374 T/A gene polymorphisms of the receptor of advanced glycation end products gene are not risk factors for diabetic retinopathy in Caucasians with type 2 diabetes. Globocnik Petrovic M, etal., Klin Monbl Augenheilkd. 2003 Dec;220(12):873-6.
38. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
39. Expression of receptor for advanced glycation end products (RAGE) on the surface of circulating endothelial cells is upregulated in Kawasaki disease. Gong F, etal., Pediatr Res. 2012 Jun;71(6):720-4. doi: 10.1038/pr.2012.27. Epub 2012 Feb 15.
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Additional References at PubMed
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Genomics

Comparative Map Data
AGER
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,180,969 - 32,184,253 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,180,968 - 32,184,322 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,148,746 - 32,152,030 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,256,724 - 32,260,001 (-)NCBINCBI36Build 36hg18NCBI36
Build 34632,256,723 - 32,260,001NCBI
Celera633,715,793 - 33,719,070 (-)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef631,902,943 - 31,906,297 (-)NCBIHuRef
CHM1_1632,151,229 - 32,154,583 (-)NCBICHM1_1
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBIT2T-CHM13v2.0
Ager
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,816,545 - 34,819,911 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,816,836 - 34,819,910 (+)EnsemblGRCm39 Ensembl
GRCm381734,597,460 - 34,600,937 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,597,862 - 34,600,936 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,734,807 - 34,737,877 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,205,945 - 34,208,989 (+)NCBIMGSCv36mm8
Celera1737,693,022 - 37,696,092 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.18NCBI
Ager
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,152,758 - 4,155,956 (-)NCBIGRCr8
mRatBN7.2204,148,150 - 4,151,361 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,147,890 - 4,151,078 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,854,742 - 4,857,677 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,216,494 - 4,219,429 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,747,395 - 4,750,329 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,363,152 - 4,366,079 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,363,152 - 4,366,079 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,442,508 - 6,445,435 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,250,613 - 4,253,540 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,250,839 - 4,253,767 (-)NCBI
Celera203,879,126 - 3,882,053 (+)NCBICelera
Cytogenetic Map20p12NCBI
Ager
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437645,897 - 648,479 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437645,482 - 648,607 (-)NCBIChiLan1.0ChiLan1.0
AGER
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,644,045 - 46,647,812 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,605,525 - 42,609,148 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,828,363 - 31,831,981 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,708,251 - 32,711,641 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,708,251 - 32,711,641 (-)Ensemblpanpan1.1panPan2
AGER
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,574,251 - 1,577,410 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,574,251 - 1,577,129 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,707,946 - 1,710,824 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,712,483 - 1,715,623 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,712,483 - 1,715,351 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,575,515 - 1,578,386 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,641,097 - 1,643,974 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,707,421 - 1,710,298 (-)NCBIUU_Cfam_GSD_1.0
Ager
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494636,139,331 - 36,142,908 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,418,799 - 1,422,147 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,418,342 - 1,422,005 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGER
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl724,218,120 - 24,221,162 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1724,218,116 - 24,221,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2728,038,957 - 28,042,327 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGER
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,847,343 - 39,851,288 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1739,847,759 - 39,851,127 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604432,080,456 - 32,084,078 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ager
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475424,138,086 - 24,140,900 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AGER
34 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3		 pathogenic
GRCh37/hg19 6p21.33-21.32(chr6:32052479-32184403)x3 copy number gain See cases [RCV000239830] Chr6:32052479..32184403 [GRCh37]
Chr6:6p21.33-21.32		 likely pathogenic|uncertain significance
GRCh37/hg19 6p21.33-21.32(chr6:31952482-32243155)x4 copy number gain See cases [RCV000446740] Chr6:31952482..32243155 [GRCh37]
Chr6:6p21.33-21.32		 uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367) copy number gain not provided [RCV000767714] Chr6:29455465..81447367 [GRCh37]
Chr6:6p22.1-q14.1		 pathogenic
NM_001136.5(AGER):c.1177G>A (p.Glu393Lys) single nucleotide variant Inborn genetic diseases [RCV003283379] Chr6:32181181 [GRCh38]
Chr6:32148958 [GRCh37]
Chr6:6p21.32		 uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
NM_001136.5(AGER):c.811T>A (p.Trp271Arg) single nucleotide variant not provided [RCV000881806] Chr6:32182579 [GRCh38]
Chr6:32150356 [GRCh37]
Chr6:6p21.32		 benign|conflicting interpretations of pathogenicity
NM_001136.5(AGER):c.902G>C (p.Cys301Ser) single nucleotide variant not provided [RCV000881805] Chr6:32182309 [GRCh38]
Chr6:32150086 [GRCh37]
Chr6:6p21.32		 benign|conflicting interpretations of pathogenicity
NM_001136.5(AGER):c.243C>T (p.Asn81=) single nucleotide variant not provided [RCV000904731] Chr6:32183667 [GRCh38]
Chr6:32151444 [GRCh37]
Chr6:6p21.32		 likely benign
NM_001136.5(AGER):c.692-9A>C single nucleotide variant not provided [RCV000922439] Chr6:32182707 [GRCh38]
Chr6:32150484 [GRCh37]
Chr6:6p21.32		 likely benign
NM_001136.5(AGER):c.941G>A (p.Arg314His) single nucleotide variant not provided [RCV000966990] Chr6:32182270 [GRCh38]
Chr6:32150047 [GRCh37]
Chr6:6p21.32		 benign
NM_001136.5(AGER):c.975G>A (p.Glu325=) single nucleotide variant not provided [RCV000918517] Chr6:32181622 [GRCh38]
Chr6:32149399 [GRCh37]
Chr6:6p21.32		 likely benign
NM_001136.5(AGER):c.925G>A (p.Gly309Arg) single nucleotide variant not provided [RCV000964471] Chr6:32182286 [GRCh38]
Chr6:32150063 [GRCh37]
Chr6:6p21.32		 likely benign
NM_001136.5(AGER):c.138C>T (p.Pro46=) single nucleotide variant not provided [RCV000919262] Chr6:32183902 [GRCh38]
Chr6:32151679 [GRCh37]
Chr6:6p21.32		 likely benign
NM_001136.5(AGER):c.842C>T (p.Pro281Leu) single nucleotide variant Inborn genetic diseases [RCV003268170] Chr6:32182369 [GRCh38]
Chr6:32150146 [GRCh37]
Chr6:6p21.32		 uncertain significance
GRCh37/hg19 6p21.33-21.32(chr6:32027371-32448599)x3 copy number gain not provided [RCV000846873] Chr6:32027371..32448599 [GRCh37]
Chr6:6p21.33-21.32		 uncertain significance
NM_001136.5(AGER):c.6= (p.Ala2=) variation not provided [RCV000950146] Chr6:32184217 [GRCh38]
Chr6:32151994 [GRCh37]
Chr6:6p21.32		 benign
NM_001136.5(AGER):c.229C>T (p.Arg77Cys) single nucleotide variant not provided [RCV000952525] Chr6:32183681 [GRCh38]
Chr6:32151458 [GRCh37]
Chr6:6p21.32		 benign
NM_001136.5(AGER):c.1106G>A (p.Arg369Gln) single nucleotide variant not provided [RCV000948730] Chr6:32181363 [GRCh38]
Chr6:32149140 [GRCh37]
Chr6:6p21.32		 benign
NM_001136.5(AGER):c.1027C>T (p.Leu343=) single nucleotide variant not provided [RCV000911191] Chr6:32181442 [GRCh38]
Chr6:32149219 [GRCh37]
Chr6:6p21.32		 benign
GRCh37/hg19 6p21.33-21.32(chr6:31916915-32278000)x3 copy number gain not provided [RCV001005792] Chr6:31916915..32278000 [GRCh37]
Chr6:6p21.33-21.32		 uncertain significance
GRCh37/hg19 6p21.33-21.31(chr6:31036397-34088832)x3 copy number gain not provided [RCV001005791] Chr6:31036397..34088832 [GRCh37]
Chr6:6p21.33-21.31		 likely pathogenic
GRCh37/hg19 6p21.33-21.32(chr6:31952482-32243155) copy number gain not specified [RCV002053565] Chr6:31952482..32243155 [GRCh37]
Chr6:6p21.33-21.32		 uncertain significance
NC_000006.11:g.(?_30695893)_(36953949_?)dup duplication Proteasome-associated autoinflammatory syndrome 1 [RCV003113679] Chr6:30695893..36953949 [GRCh37]
Chr6:6p21.33-21.2		 uncertain significance
NM_001136.5(AGER):c.653G>A (p.Arg218Gln) single nucleotide variant Inborn genetic diseases [RCV002901954] Chr6:32182879 [GRCh38]
Chr6:32150656 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.169C>T (p.Arg57Trp) single nucleotide variant Inborn genetic diseases [RCV002969167] Chr6:32183741 [GRCh38]
Chr6:32151518 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.754G>A (p.Gly252Ser) single nucleotide variant Inborn genetic diseases [RCV002688310] Chr6:32182636 [GRCh38]
Chr6:32150413 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.242A>G (p.Asn81Ser) single nucleotide variant Inborn genetic diseases [RCV002817606] Chr6:32183668 [GRCh38]
Chr6:32151445 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.737G>A (p.Gly246Asp) single nucleotide variant Inborn genetic diseases [RCV002703850] Chr6:32182653 [GRCh38]
Chr6:32150430 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.88A>G (p.Ile30Val) single nucleotide variant Inborn genetic diseases [RCV002980463] Chr6:32183952 [GRCh38]
Chr6:32151729 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.782T>A (p.Val261Asp) single nucleotide variant Inborn genetic diseases [RCV002709476] Chr6:32182608 [GRCh38]
Chr6:32150385 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.188T>G (p.Val63Gly) single nucleotide variant Inborn genetic diseases [RCV002874018] Chr6:32183722 [GRCh38]
Chr6:32151499 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.1124C>T (p.Ala375Val) single nucleotide variant Inborn genetic diseases [RCV002831166] Chr6:32181234 [GRCh38]
Chr6:32149011 [GRCh37]
Chr6:6p21.32		 likely benign
NM_001136.5(AGER):c.878C>T (p.Pro293Leu) single nucleotide variant Inborn genetic diseases [RCV002935040] Chr6:32182333 [GRCh38]
Chr6:32150110 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.826G>A (p.Val276Met) single nucleotide variant Inborn genetic diseases [RCV002670463] Chr6:32182385 [GRCh38]
Chr6:32150162 [GRCh37]
Chr6:6p21.32		 likely benign
NM_001136.5(AGER):c.114T>G (p.Cys38Trp) single nucleotide variant Inborn genetic diseases [RCV002679077] Chr6:32183926 [GRCh38]
Chr6:32151703 [GRCh37]
Chr6:6p21.32		 uncertain significance
NC_000006.11:g.(?_32148920)_(36953949_?)dup duplication not provided [RCV003154914] Chr6:32148920..36953949 [GRCh37]
Chr6:6p21.32-21.2		 uncertain significance
NM_001136.5(AGER):c.920G>T (p.Ser307Ile) single nucleotide variant Inborn genetic diseases [RCV003220638] Chr6:32182291 [GRCh38]
Chr6:32150068 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.208G>A (p.Gly70Ser) single nucleotide variant Inborn genetic diseases [RCV003197822] Chr6:32183702 [GRCh38]
Chr6:32151479 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.763G>A (p.Val255Ile) single nucleotide variant Inborn genetic diseases [RCV003265894] Chr6:32182627 [GRCh38]
Chr6:32150404 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.1165A>C (p.Asn389His) single nucleotide variant Inborn genetic diseases [RCV003368934] Chr6:32181193 [GRCh38]
Chr6:32148970 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.10G>A (p.Gly4Arg) single nucleotide variant Inborn genetic diseases [RCV003354761] Chr6:32184213 [GRCh38]
Chr6:32151990 [GRCh37]
Chr6:6p21.32		 uncertain significance
NM_001136.5(AGER):c.914A>G (p.His305Arg) single nucleotide variant Inborn genetic diseases [RCV003352296] Chr6:32182297 [GRCh38]
Chr6:32150074 [GRCh37]
Chr6:6p21.32		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3725
Count of miRNA genes:702
Interacting mature miRNAs:850
Transcripts:ENST00000375055, ENST00000375056, ENST00000375065, ENST00000375067, ENST00000375069, ENST00000375070, ENST00000375076, ENST00000438221, ENST00000450110, ENST00000469940, ENST00000473619, ENST00000484849, ENST00000488669, ENST00000538695
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH40485  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37838,457,853 - 38,457,999UniSTSGRCh37
GRCh37632,148,283 - 32,148,429UniSTSGRCh37
Build 36632,256,261 - 32,256,407RGDNCBI36
Celera837,411,195 - 37,411,341UniSTS
Celera633,715,330 - 33,715,476RGD
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef836,993,139 - 36,993,285UniSTS
HuRef631,902,481 - 31,902,627UniSTS
RH65115  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37838,457,740 - 38,457,970UniSTSGRCh37
GRCh37632,148,312 - 32,148,542UniSTSGRCh37
Build 36632,256,290 - 32,256,520RGDNCBI36
Celera837,411,082 - 37,411,312UniSTS
Celera633,715,359 - 33,715,589RGD
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef836,993,026 - 36,993,256UniSTS
HuRef631,902,510 - 31,902,740UniSTS
RH67947  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37838,457,785 - 38,457,875UniSTSGRCh37
GRCh37632,148,407 - 32,148,497UniSTSGRCh37
Build 36632,256,385 - 32,256,475RGDNCBI36
Celera837,411,127 - 37,411,217UniSTS
Celera633,715,454 - 33,715,544RGD
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef836,993,071 - 36,993,161UniSTS
HuRef631,902,605 - 31,902,695UniSTS
RH46823  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,153,445 - 32,153,615UniSTSGRCh37
GRCh373142,897,006 - 142,897,184UniSTSGRCh37
Build 363144,379,696 - 144,379,874RGDNCBI36
Celera633,720,489 - 33,720,659UniSTS
Celera3141,320,402 - 141,320,579RGD
Cytogenetic Map3q24UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef631,907,640 - 31,907,810UniSTS
HuRef3140,269,283 - 140,269,459UniSTS
GDB:607721  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,153,249 - 32,154,023UniSTSGRCh37
GRCh373142,896,599 - 142,897,372UniSTSGRCh37
Build 363144,379,289 - 144,380,062RGDNCBI36
Celera633,720,296 - 33,721,067UniSTS
Celera3141,319,995 - 141,320,768RGD
Cytogenetic Map3q24UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef631,907,447 - 31,908,218UniSTS
HuRef3140,268,876 - 140,269,648UniSTS
PMC162222P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,150,442 - 32,151,423UniSTSGRCh37
Build 36632,258,420 - 32,259,401RGDNCBI36
Celera633,717,489 - 33,718,470RGD
Cytogenetic Map6p21.3UniSTS
HuRef631,904,640 - 31,905,621UniSTS
PMC203021P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,150,444 - 32,150,915UniSTSGRCh37
Build 36632,258,422 - 32,258,893RGDNCBI36
Celera633,717,491 - 33,717,962RGD
Cytogenetic Map6p21.3UniSTS
HuRef631,904,642 - 31,905,113UniSTS
D3S4540  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,153,242 - 32,153,518UniSTSGRCh37
GRCh373142,897,103 - 142,897,379UniSTSGRCh37
Build 363144,379,793 - 144,380,069RGDNCBI36
Celera633,720,289 - 33,720,562UniSTS
Celera3141,320,499 - 141,320,775RGD
Cytogenetic Map3q24UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef631,907,440 - 31,907,713UniSTS
HuRef3140,269,380 - 140,269,655UniSTS
D6S1871  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,148,745 - 32,148,919UniSTSGRCh37
Build 36632,256,723 - 32,256,897RGDNCBI36
Celera633,715,792 - 33,715,966RGD
Cytogenetic Map6p21.3UniSTS
HuRef631,902,943 - 31,903,117UniSTS
Stanford-G3 RH Map61672.0UniSTS
GeneMap99-GB4 RH Map6145.45UniSTS
GeneMap99-GB4 RH Map6120.03UniSTS
Whitehead-RH Map6179.7UniSTS
NCBI RH Map6509.1UniSTS
GeneMap99-G3 RH Map61804.0UniSTS
STS-D60277  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37838,457,758 - 38,457,875UniSTSGRCh37
GRCh37632,148,407 - 32,148,524UniSTSGRCh37
Build 36632,256,385 - 32,256,502RGDNCBI36
Celera633,715,454 - 33,715,571RGD
Celera837,411,100 - 37,411,217UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map8p11.22UniSTS
HuRef836,993,044 - 36,993,161UniSTS
HuRef631,902,605 - 31,902,722UniSTS
GeneMap99-GB4 RH Map6120.03UniSTS
NCBI RH Map6509.1UniSTS
MARC_10431-10432:999637141:1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,151,138 - 32,151,505UniSTSGRCh37
Build 36632,259,116 - 32,259,483RGDNCBI36
Celera633,718,185 - 33,718,552RGD
HuRef631,905,336 - 31,905,703UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High 314
Medium 1503 1222 1104 92 1543 53 1779 728 1451 126 1142 1089 43 511 1106 1
Low 929 1762 611 522 405 403 2576 1465 2249 286 305 206 127 693 1682 3
Below cutoff 8 8 8 9 6 2 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_172197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_038190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047418260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047418261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054328451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054328452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054328453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054329741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054329742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054329743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054354413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054354414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054354415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001743189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001743190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB036432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB061668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB061669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF001095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF065211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF065212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF208289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF502127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF536236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF536237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF537303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ012753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ133822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ238896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL845464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM971899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX284686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX927239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR812478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR933878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS300822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D28769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ104251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ104252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ104253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ104254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU117141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU428811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU428812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU428813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU428814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU428815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU428816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU826616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU826617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU826618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU826619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU826620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ545655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ148133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ148134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ148135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC692917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M91211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  ON814573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  ON814574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  ON814575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  ON814576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  ON814577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  PP412807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U89336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y18060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y18061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000375055   ⟹   ENSP00000364195
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,180,968 - 32,184,246 (-)Ensembl
RefSeq Acc Id: ENST00000375056   ⟹   ENSP00000364196
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,182,880 - 32,184,237 (-)Ensembl
RefSeq Acc Id: ENST00000375065   ⟹   ENSP00000364206
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,181,143 - 32,184,222 (-)Ensembl
RefSeq Acc Id: ENST00000375067   ⟹   ENSP00000364208
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,180,968 - 32,184,237 (-)Ensembl
RefSeq Acc Id: ENST00000375069   ⟹   ENSP00000364210
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,180,968 - 32,184,322 (-)Ensembl
RefSeq Acc Id: ENST00000375070   ⟹   ENSP00000364211
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,180,968 - 32,184,322 (-)Ensembl
RefSeq Acc Id: ENST00000375076   ⟹   ENSP00000364217
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,180,969 - 32,184,253 (-)Ensembl
RefSeq Acc Id: ENST00000438221   ⟹   ENSP00000387887
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,180,968 - 32,184,322 (-)Ensembl
RefSeq Acc Id: ENST00000450110   ⟹   ENSP00000398466
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,182,868 - 32,184,235 (-)Ensembl
RefSeq Acc Id: ENST00000469940
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,180,968 - 32,181,635 (-)Ensembl
RefSeq Acc Id: ENST00000473619
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,180,968 - 32,182,931 (-)Ensembl
RefSeq Acc Id: ENST00000484849
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,180,968 - 32,184,246 (-)Ensembl
RefSeq Acc Id: ENST00000488669
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,180,968 - 32,182,931 (-)Ensembl
RefSeq Acc Id: ENST00000538695   ⟹   ENSP00000445389
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,183,409 - 32,184,322 (-)Ensembl
RefSeq Acc Id: ENST00000620802   ⟹   ENSP00000484081
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,180,968 - 32,184,322 (-)Ensembl
RefSeq Acc Id: NM_001136   ⟹   NP_001127
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
Build 36632,256,724 - 32,260,001 (-)NCBI Archive
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206929   ⟹   NP_001193858
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206932   ⟹   NP_001193861
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206934   ⟹   NP_001193863
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206936   ⟹   NP_001193865
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206940   ⟹   NP_001193869
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206954   ⟹   NP_001193883
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206966   ⟹   NP_001193895
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_172197   ⟹   NP_751947
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
Build 36632,256,724 - 32,260,001 (-)NCBI Archive
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NR_038190
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010328   ⟹   XP_016865817
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047418260   ⟹   XP_047274216
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,181,357 - 32,184,253 (-)NCBI
RefSeq Acc Id: XM_047418261   ⟹   XP_047274217
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,181,357 - 32,184,253 (-)NCBI
RefSeq Acc Id: XM_054354413   ⟹   XP_054210388
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
RefSeq Acc Id: XM_054354414   ⟹   XP_054210389
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0632,034,548 - 32,037,444 (-)NCBI
RefSeq Acc Id: XM_054354415   ⟹   XP_054210390
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0632,034,548 - 32,037,444 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001127 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193858 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193861 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193863 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193865 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193869 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193883 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193895 (Get FASTA)   NCBI Sequence Viewer  
  NP_751947 (Get FASTA)   NCBI Sequence Viewer  
  XP_016865817 (Get FASTA)   NCBI Sequence Viewer  
  XP_047274216 (Get FASTA)   NCBI Sequence Viewer  
  XP_047274217 (Get FASTA)   NCBI Sequence Viewer  
  XP_054184426 (Get FASTA)   NCBI Sequence Viewer  
  XP_054184427 (Get FASTA)   NCBI Sequence Viewer  
  XP_054184428 (Get FASTA)   NCBI Sequence Viewer  
  XP_054185716 (Get FASTA)   NCBI Sequence Viewer  
  XP_054185717 (Get FASTA)   NCBI Sequence Viewer  
  XP_054185718 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186504 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186505 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186506 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186751 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186752 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186753 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186987 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186988 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186989 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187253 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187254 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187255 (Get FASTA)   NCBI Sequence Viewer  
  XP_054210388 (Get FASTA)   NCBI Sequence Viewer  
  XP_054210389 (Get FASTA)   NCBI Sequence Viewer  
  XP_054210390 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA03574 (Get FASTA)   NCBI Sequence Viewer  
  AAB47491 (Get FASTA)   NCBI Sequence Viewer  
  AAD15888 (Get FASTA)   NCBI Sequence Viewer  
  AAD15889 (Get FASTA)   NCBI Sequence Viewer  
  AAG35728 (Get FASTA)   NCBI Sequence Viewer  
  AAH20669 (Get FASTA)   NCBI Sequence Viewer  
  AAQ10685 (Get FASTA)   NCBI Sequence Viewer  
  AAQ10686 (Get FASTA)   NCBI Sequence Viewer  
  AAQ10782 (Get FASTA)   NCBI Sequence Viewer  
  AAX07272 (Get FASTA)   NCBI Sequence Viewer  
  AAX07273 (Get FASTA)   NCBI Sequence Viewer  
  AAX07274 (Get FASTA)   NCBI Sequence Viewer  
  AAX07275 (Get FASTA)   NCBI Sequence Viewer  
  AAX07276 (Get FASTA)   NCBI Sequence Viewer  
  AAX07277 (Get FASTA)   NCBI Sequence Viewer  
  AAX07278 (Get FASTA)   NCBI Sequence Viewer  
  AAX07279 (Get FASTA)   NCBI Sequence Viewer  
  AAX07280 (Get FASTA)   NCBI Sequence Viewer  
  AAX07281 (Get FASTA)   NCBI Sequence Viewer  
  AAZ32412 (Get FASTA)   NCBI Sequence Viewer  
  AAZ32413 (Get FASTA)   NCBI Sequence Viewer  
  AAZ32414 (Get FASTA)   NCBI Sequence Viewer  
  AAZ32415 (Get FASTA)   NCBI Sequence Viewer  
  ABV03807 (Get FASTA)   NCBI Sequence Viewer  
  ACE78167 (Get FASTA)   NCBI Sequence Viewer  
  ACE78168 (Get FASTA)   NCBI Sequence Viewer  
  ACE78169 (Get FASTA)   NCBI Sequence Viewer  
  ACE78170 (Get FASTA)   NCBI Sequence Viewer  
  ACF47652 (Get FASTA)   NCBI Sequence Viewer  
  ACF47653 (Get FASTA)   NCBI Sequence Viewer  
  ACF47654 (Get FASTA)   NCBI Sequence Viewer  
  ACF47655 (Get FASTA)   NCBI Sequence Viewer  
  ACF47656 (Get FASTA)   NCBI Sequence Viewer  
  ACL80027 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42256 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42257 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42258 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42259 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42260 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42261 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42262 (Get FASTA)   NCBI Sequence Viewer  
  ADV92535 (Get FASTA)   NCBI Sequence Viewer  
  ADV92536 (Get FASTA)   NCBI Sequence Viewer  
  ADV92537 (Get FASTA)   NCBI Sequence Viewer  
  AHB30241 (Get FASTA)   NCBI Sequence Viewer  
  AQY76648 (Get FASTA)   NCBI Sequence Viewer  
  AQY76649 (Get FASTA)   NCBI Sequence Viewer  
  AQY76650 (Get FASTA)   NCBI Sequence Viewer  
  AQY76651 (Get FASTA)   NCBI Sequence Viewer  
  AQY76652 (Get FASTA)   NCBI Sequence Viewer  
  BAA05958 (Get FASTA)   NCBI Sequence Viewer  
  BAA89369 (Get FASTA)   NCBI Sequence Viewer  
  BAC65465 (Get FASTA)   NCBI Sequence Viewer  
  BAC65466 (Get FASTA)   NCBI Sequence Viewer  
  BAG35995 (Get FASTA)   NCBI Sequence Viewer  
  BAG60385 (Get FASTA)   NCBI Sequence Viewer  
  CAA10169 (Get FASTA)   NCBI Sequence Viewer  
  CAB43094 (Get FASTA)   NCBI Sequence Viewer  
  CAB43108 (Get FASTA)   NCBI Sequence Viewer  
  CAK32486 (Get FASTA)   NCBI Sequence Viewer  
  EAX03610 (Get FASTA)   NCBI Sequence Viewer  
  EAX03611 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000364195
  ENSP00000364195.2
  ENSP00000364196.2
  ENSP00000364208
  ENSP00000364208.3
  ENSP00000364210
  ENSP00000364210.4
  ENSP00000364211.4
  ENSP00000364217
  ENSP00000364217.4
  ENSP00000372762.2
  ENSP00000372766.4
  ENSP00000387853.2
  ENSP00000387887
  ENSP00000387887.2
  ENSP00000388041.1
  ENSP00000388462.2
  ENSP00000391024.1
  ENSP00000391743.2
  ENSP00000391970.2
  ENSP00000394516.1
  ENSP00000395578.1
  ENSP00000395812.2
  ENSP00000397227.2
  ENSP00000397350.1
  ENSP00000397777.2
  ENSP00000398466.1
  ENSP00000399134.1
  ENSP00000399686.1
  ENSP00000400667.1
  ENSP00000401068.2
  ENSP00000401896.1
  ENSP00000403322.1
  ENSP00000407467.1
  ENSP00000409457.2
  ENSP00000410918.1
  ENSP00000411203.1
  ENSP00000411652.1
  ENSP00000412576.1
  ENSP00000413391.1
  ENSP00000415144.2
  ENSP00000415780.1
  ENSP00000416042.2
  ENSP00000445389.1
  ENSP00000446495.1
  ENSP00000446533.1
  ENSP00000446582.1
  ENSP00000446660.1
  ENSP00000446682.2
  ENSP00000446692.1
  ENSP00000446835.1
  ENSP00000447095.1
  ENSP00000447301.2
  ENSP00000447531.1
  ENSP00000448028.1
  ENSP00000448142.1
  ENSP00000448234.1
  ENSP00000448287.1
  ENSP00000448486.1
  ENSP00000448525.1
  ENSP00000448579.2
  ENSP00000448979.2
  ENSP00000449037.1
  ENSP00000449040.1
  ENSP00000449042.1
  ENSP00000449091.1
  ENSP00000449100.1
  ENSP00000449143.1
  ENSP00000449226.1
  ENSP00000449368.1
  ENSP00000449506.1
  ENSP00000449676.1
  ENSP00000449708.1
  ENSP00000449731.2
  ENSP00000449754.1
  ENSP00000449769.1
  ENSP00000449931.1
  ENSP00000449997.1
  ENSP00000450134.2
  ENSP00000450205.1
GenBank Protein Q15109 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001193861   ⟸   NM_001206932
- Peptide Label: isoform 3 precursor
- UniProtKB: A0A1U9X782 (UniProtKB/TrEMBL),   A0A1U9X790 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_751947   ⟸   NM_172197
- Peptide Label: isoform 7 precursor
- UniProtKB: A0A0G2JID9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193883   ⟸   NM_001206954
- Peptide Label: isoform 8 precursor
- UniProtKB: Q101R5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193865   ⟸   NM_001206936
- Peptide Label: isoform 5 precursor
- UniProtKB: Q101R5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001127   ⟸   NM_001136
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9Y3R3 (UniProtKB/Swiss-Prot),   Q9H2X7 (UniProtKB/Swiss-Prot),   Q86SN1 (UniProtKB/Swiss-Prot),   Q3L1S0 (UniProtKB/Swiss-Prot),   Q3L1R8 (UniProtKB/Swiss-Prot),   Q3L1R7 (UniProtKB/Swiss-Prot),   Q3L1R6 (UniProtKB/Swiss-Prot),   Q3L1R5 (UniProtKB/Swiss-Prot),   Q3L1R4 (UniProtKB/Swiss-Prot),   Q15279 (UniProtKB/Swiss-Prot),   B0V176 (UniProtKB/Swiss-Prot),   A7Y2U9 (UniProtKB/Swiss-Prot),   A6NKF0 (UniProtKB/Swiss-Prot),   A2BFI7 (UniProtKB/Swiss-Prot),   V5R6A3 (UniProtKB/Swiss-Prot),   Q15109 (UniProtKB/Swiss-Prot),   A0A1U9X785 (UniProtKB/TrEMBL),   A0A1U9X782 (UniProtKB/TrEMBL),   A0A1U9X790 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193895   ⟸   NM_001206966
- Peptide Label: isoform 6 precursor
- UniProtKB: A0A0G2JJF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193869   ⟸   NM_001206940
- Peptide Label: isoform 6 precursor
- UniProtKB: A0A0G2JJF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193858   ⟸   NM_001206929
- Peptide Label: isoform 2 precursor
- UniProtKB: A0A0G2JL65 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193863   ⟸   NM_001206934
- Peptide Label: isoform 4 precursor
- UniProtKB: A0A0G2JL37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016865817   ⟸   XM_017010328
- Peptide Label: isoform X1
- UniProtKB: Q101R5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000387887   ⟸   ENST00000438221
RefSeq Acc Id: ENSP00000484081   ⟸   ENST00000620802
RefSeq Acc Id: ENSP00000398466   ⟸   ENST00000450110
RefSeq Acc Id: ENSP00000364196   ⟸   ENST00000375056
RefSeq Acc Id: ENSP00000364195   ⟸   ENST00000375055
RefSeq Acc Id: ENSP00000364208   ⟸   ENST00000375067
RefSeq Acc Id: ENSP00000364206   ⟸   ENST00000375065
RefSeq Acc Id: ENSP00000364210   ⟸   ENST00000375069
RefSeq Acc Id: ENSP00000364211   ⟸   ENST00000375070
RefSeq Acc Id: ENSP00000364217   ⟸   ENST00000375076
RefSeq Acc Id: ENSP00000445389   ⟸   ENST00000538695
RefSeq Acc Id: XP_047274217   ⟸   XM_047418261
- Peptide Label: isoform X3
- UniProtKB: Q101R3 (UniProtKB/TrEMBL),   Q101R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047274216   ⟸   XM_047418260
- Peptide Label: isoform X2
- UniProtKB: Q101R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054210388   ⟸   XM_054354413
- Peptide Label: isoform X1
- UniProtKB: Q101R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054210390   ⟸   XM_054354415
- Peptide Label: isoform X3
- UniProtKB: Q101R3 (UniProtKB/TrEMBL),   Q101R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054210389   ⟸   XM_054354414
- Peptide Label: isoform X2
- UniProtKB: Q101R5 (UniProtKB/TrEMBL)
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q15109-F1-model_v2 AlphaFold Q15109 1-404 view protein structure

Promoters
RGD ID:6872772
Promoter ID:EPDNEW_H9551
Type:initiation region
Name:AGER_1
Description:advanced glycosylation end-product specific receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,184,253 - 32,184,313EPDNEW
RGD ID:6803738
Promoter ID:HG_KWN:53077
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   K562,   Lymphoblastoid
Transcripts:OTTHUMT00000076204
Position:
Human AssemblyChrPosition (strand)Source
Build 36632,256,901 - 32,258,322 (-)MPROMDB
RGD ID:6803740
Promoter ID:HG_KWN:53078
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   K562,   Lymphoblastoid
Transcripts:OTTHUMT00000268939,   OTTHUMT00000268940
Position:
Human AssemblyChrPosition (strand)Source
Build 36632,258,401 - 32,259,252 (-)MPROMDB
RGD ID:6803749
Promoter ID:HG_KWN:53079
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000375055,   ENST00000375056,   ENST00000375059,   ENST00000375061,   ENST00000375065,   ENST00000375069,   ENST00000375070,   OTTHUMT00000076200,   OTTHUMT00000076201,   OTTHUMT00000076202,   OTTHUMT00000076203,   OTTHUMT00000268938,   UC003OAM.1,   UC003OAO.1,   UC003OAQ.1,   UC003OAT.1,   UC010JTV.1,   UC010JTW.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36632,259,631 - 32,260,131 (-)MPROMDB
RGD ID:6852566
Promoter ID:EP74095
Type:initiation region
Name:HS_AGER
Description:Advanced glycosylation end product-specific receptor.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Mammalian gene collection (MGC) full-length cDNA cloning
Position:
Human AssemblyChrPosition (strand)Source
Build 36632,260,015 - 32,260,075EPD

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:320 AgrOrtholog
COSMIC AGER COSMIC
Ensembl Genes ENSG00000204305 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000206320 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000229058 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000230514 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000231268 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000234729 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000237405 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000375055 ENTREZGENE
  ENST00000375055.6 UniProtKB/Swiss-Prot
  ENST00000375056.6 UniProtKB/TrEMBL
  ENST00000375067 ENTREZGENE
  ENST00000375067.7 UniProtKB/Swiss-Prot
  ENST00000375069 ENTREZGENE
  ENST00000375069.7 UniProtKB/Swiss-Prot
  ENST00000375070.7 UniProtKB/TrEMBL
  ENST00000375076 ENTREZGENE
  ENST00000375076.9 UniProtKB/Swiss-Prot
  ENST00000383275.6 UniProtKB/Swiss-Prot
  ENST00000383279.8 UniProtKB/Swiss-Prot
  ENST00000412470.6 UniProtKB/Swiss-Prot
  ENST00000412794.5 UniProtKB/TrEMBL
  ENST00000415973.5 UniProtKB/TrEMBL
  ENST00000416532.5 UniProtKB/TrEMBL
  ENST00000418313.5 UniProtKB/TrEMBL
  ENST00000424145.6 UniProtKB/TrEMBL
  ENST00000424476.5 UniProtKB/TrEMBL
  ENST00000426138.6 UniProtKB/Swiss-Prot
  ENST00000426320.5 UniProtKB/TrEMBL
  ENST00000427822.6 UniProtKB/Swiss-Prot
  ENST00000432831.5 UniProtKB/Swiss-Prot
  ENST00000434502.5 UniProtKB/TrEMBL
  ENST00000436456.6 UniProtKB/Swiss-Prot
  ENST00000436653.5 UniProtKB/TrEMBL
  ENST00000438221 ENTREZGENE
  ENST00000438221.6 UniProtKB/Swiss-Prot
  ENST00000441180.6 UniProtKB/Swiss-Prot
  ENST00000441753.5 UniProtKB/TrEMBL
  ENST00000441804.6 UniProtKB/Swiss-Prot
  ENST00000444630.5 UniProtKB/TrEMBL
  ENST00000447921.6 UniProtKB/Swiss-Prot
  ENST00000448768.6 UniProtKB/TrEMBL
  ENST00000449037.5 UniProtKB/Swiss-Prot
  ENST00000450110.5 UniProtKB/TrEMBL
  ENST00000451115.6 UniProtKB/Swiss-Prot
  ENST00000452945.5 UniProtKB/TrEMBL
  ENST00000453119.5 UniProtKB/TrEMBL
  ENST00000453588.5 UniProtKB/Swiss-Prot
  ENST00000454284.5 UniProtKB/TrEMBL
  ENST00000455471.5 UniProtKB/TrEMBL
  ENST00000456918.6 UniProtKB/Swiss-Prot
  ENST00000484849 ENTREZGENE
  ENST00000538695.2 UniProtKB/TrEMBL
  ENST00000546535.2 UniProtKB/TrEMBL
  ENST00000547155.5 UniProtKB/TrEMBL
  ENST00000547213.5 UniProtKB/TrEMBL
  ENST00000547328.5 UniProtKB/Swiss-Prot
  ENST00000547651.2 UniProtKB/Swiss-Prot
  ENST00000547770.5 UniProtKB/TrEMBL
  ENST00000548009.4 UniProtKB/TrEMBL
  ENST00000548034.3 UniProtKB/TrEMBL
  ENST00000548464.3 UniProtKB/Swiss-Prot
  ENST00000548935.4 UniProtKB/TrEMBL
  ENST00000548959.5 UniProtKB/TrEMBL
  ENST00000549168.4 UniProtKB/TrEMBL
  ENST00000549227.5 UniProtKB/TrEMBL
  ENST00000549626.3 UniProtKB/TrEMBL
  ENST00000549758.5 UniProtKB/Swiss-Prot
  ENST00000549776.3 UniProtKB/TrEMBL
  ENST00000549839.5 UniProtKB/TrEMBL
  ENST00000550196.5 UniProtKB/TrEMBL
  ENST00000550441.5 UniProtKB/TrEMBL
  ENST00000550562.5 UniProtKB/Swiss-Prot
  ENST00000550854.5 UniProtKB/TrEMBL
  ENST00000550885.5 UniProtKB/TrEMBL
  ENST00000550959.5 UniProtKB/TrEMBL
  ENST00000551244.4 UniProtKB/TrEMBL
  ENST00000551254.5 UniProtKB/Swiss-Prot
  ENST00000551378.4 UniProtKB/TrEMBL
  ENST00000551381.5 UniProtKB/Swiss-Prot
  ENST00000551677.3 UniProtKB/TrEMBL
  ENST00000551684.5 UniProtKB/TrEMBL
  ENST00000551827.4 UniProtKB/Swiss-Prot
  ENST00000552209.5 UniProtKB/TrEMBL
  ENST00000552517.5 UniProtKB/TrEMBL
  ENST00000552621.4 UniProtKB/TrEMBL
  ENST00000552891.5 UniProtKB/TrEMBL
  ENST00000552991.5 UniProtKB/TrEMBL
  ENST00000553014.5 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000204305 GTEx
  ENSG00000206320 GTEx
  ENSG00000229058 GTEx
  ENSG00000230514 GTEx
  ENSG00000231268 GTEx
  ENSG00000234729 GTEx
  ENSG00000237405 GTEx
HGNC ID HGNC:320 ENTREZGENE
Human Proteome Map AGER Human Proteome Map
InterPro CD80_C2-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:177 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 177 ENTREZGENE
OMIM 600214 OMIM
PANTHER ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CELL SURFACE GLYCOPROTEIN MUC18-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_2 UniProtKB/TrEMBL
  Ig_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00047 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA24617 PharmGKB
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_MHC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JID9 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JJF5 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JJW2_HUMAN UniProtKB/TrEMBL
  A0A0G2JKB6_HUMAN UniProtKB/TrEMBL
  A0A0G2JL21_HUMAN UniProtKB/TrEMBL
  A0A0G2JL23_HUMAN UniProtKB/TrEMBL
  A0A0G2JL37 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JL65 ENTREZGENE, UniProtKB/TrEMBL
  A0A1U9X782 ENTREZGENE, UniProtKB/TrEMBL
  A0A1U9X785 ENTREZGENE, UniProtKB/TrEMBL
  A0A1U9X790 ENTREZGENE, UniProtKB/TrEMBL
  A2BFI7 ENTREZGENE
  A6NKF0 ENTREZGENE
  A7Y2U9 ENTREZGENE
  A8MS87_HUMAN UniProtKB/TrEMBL
  B0V176 ENTREZGENE
  B4DNX3_HUMAN UniProtKB/TrEMBL
  B5A982_HUMAN UniProtKB/TrEMBL
  C0IP14_HUMAN UniProtKB/TrEMBL
  C0IP16_HUMAN UniProtKB/TrEMBL
  E9LVY5_HUMAN UniProtKB/TrEMBL
  E9LVY6_HUMAN UniProtKB/TrEMBL
  E9LVY7_HUMAN UniProtKB/TrEMBL
  F1ABM9_HUMAN UniProtKB/TrEMBL
  F1ABN0_HUMAN UniProtKB/TrEMBL
  F1ABN1_HUMAN UniProtKB/TrEMBL
  F1ABN2_HUMAN UniProtKB/TrEMBL
  F1ABN3_HUMAN UniProtKB/TrEMBL
  F1ABN4_HUMAN UniProtKB/TrEMBL
  F1ABN5_HUMAN UniProtKB/TrEMBL
  Q101R2_HUMAN UniProtKB/TrEMBL
  Q101R3 ENTREZGENE, UniProtKB/TrEMBL
  Q101R5 ENTREZGENE, UniProtKB/TrEMBL
  Q15109 ENTREZGENE
  Q15279 ENTREZGENE
  Q3L1R2_HUMAN UniProtKB/TrEMBL
  Q3L1R3_HUMAN UniProtKB/TrEMBL
  Q3L1R4 ENTREZGENE
  Q3L1R5 ENTREZGENE
  Q3L1R6 ENTREZGENE
  Q3L1R7 ENTREZGENE
  Q3L1R8 ENTREZGENE
  Q3L1S0 ENTREZGENE
  Q5SSZ2_HUMAN UniProtKB/TrEMBL
  Q5SSZ3_HUMAN UniProtKB/TrEMBL
  Q71BB6_HUMAN UniProtKB/TrEMBL
  Q71BG7_HUMAN UniProtKB/TrEMBL
  Q86SN1 ENTREZGENE
  Q9H2X7 ENTREZGENE
  Q9Y3R3 ENTREZGENE
  RAGE_HUMAN UniProtKB/Swiss-Prot
  V5R6A3 ENTREZGENE
UniProt Secondary A2BFI7 UniProtKB/Swiss-Prot
  A6NKF0 UniProtKB/Swiss-Prot
  A7Y2U9 UniProtKB/Swiss-Prot
  B0V176 UniProtKB/Swiss-Prot
  C0IP17 UniProtKB/TrEMBL
  Q15279 UniProtKB/Swiss-Prot
  Q3L1R4 UniProtKB/Swiss-Prot
  Q3L1R5 UniProtKB/Swiss-Prot
  Q3L1R6 UniProtKB/Swiss-Prot
  Q3L1R7 UniProtKB/Swiss-Prot
  Q3L1R8 UniProtKB/Swiss-Prot
  Q3L1S0 UniProtKB/Swiss-Prot
  Q5JP26 UniProtKB/TrEMBL
  Q86SN1 UniProtKB/Swiss-Prot
  Q9H2X7 UniProtKB/Swiss-Prot
  Q9Y3R3 UniProtKB/Swiss-Prot
  V5R6A3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-26 AGER  advanced glycosylation end-product specific receptor    advanced glycosylation end product-specific receptor  Symbol and/or name change 5135510 APPROVED