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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69258
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ager
Name: advanced glycosylation end product-specific receptor
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agerincreases expressionISOAGER (Homo sapiens)6480464CTDEstradiol results in increased expression of AGER mRNA; Estradiol results in increased expression of AGER proteinPMID:15878629
Agermultiple interactionsISOAGER (Homo sapiens)6480464CTDESR1 protein promotes the reaction [Estradiol results in increased expression of AGER protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of AGER protein]PMID:15878629
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