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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69258
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ager
Name: advanced glycosylation end product-specific receptor
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agermultiple interactionsEXP 6480464CTD[Ozone co-treated with Chlorine] results in increased expression of AGER mRNA; [Ozone co-treated with Vehicle Emissions] results in increased expression of AGER mRNAPMID:18636392 PMID:20980218
Agermultiple interactionsISOAGER (Homo sapiens)6480464CTD[Air Pollutants results in increased abundance of Ozone] which affects the expression of AGER mRNAPMID:35430440
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