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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69258
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ager
Name: advanced glycosylation end product-specific receptor
Acc ID: CHEBI:28757
Term: fructose
Definition: A ketohexose that is an isomer of glucose.
Chemical ID: MESH:D005632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agerincreases expressionEXP 6480464CTDFructose results in increased expression of AGER proteinPMID:21704028 PMID:25679220
Agermultiple interactionsEXP 6480464CTDGenistein inhibits the reaction [Fructose results in increased expression of AGER protein]; geraniol inhibits the reaction [Fructose results in increased expression of AGER protein]; Pioglitazone inhibits the reaction [Fructose results in increased expression of AGER protein]PMID:21704028 PMID:25679220
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