Gene: Psmb8 (proteasome subunit beta 8) Rattus norvegicus
Symbol: Psmb8
Name: proteasome subunit beta 8
Description: ENCODES a protein that exhibits threonine-type endopeptidase activity (inferred); INVOLVED IN antigen processing and presentation (ortholog); fat cell differentiation (ortholog); regulation of endopeptidase activity (ortholog); PARTICIPATES IN ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Autoinflammation, Lipodystrophy, and Dermatosis Syndrome (ortholog); Diabetes Mellitus, Type 1 (ortholog); Liver Cirrhosis, Experimental (ortholog); FOUND IN extracellular exosome (ortholog); proteasome complex (ortholog); proteasome core complex (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: large multifunctional protease 7; Lmp7; low molecular mass polypeptide 7; macropain subunit C13; MGC124945; multicatalytic endopeptidase complex subunit C13; proteasome (prosome macropain) subunit beta type 8 (low molecular mass polypeptide 7); proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7); proteasome (prosome, macropain) subunit, beta type, 8; proteasome component C13; proteasome subunit beta type-8; proteasome subunit beta-5i; proteosome (prosome macropain) subunit beta type 8 (large multifunctional protease 7); proteosome (prosome, macropain) subunit, beta type 8; Ring10
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0203,990,809 - 3,993,772 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0206,070,355 - 6,073,317 (+)NCBIRnor5.0rn5Rnor5.0
Rnor_5.0207,275,040 - 7,276,378 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4204,786,260 - 4,789,223 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,786,490 - 4,789,389 (-)NCBI
Celera206,253,214 - 6,256,177 (-)NCBI
Cytogenetic Map20p12NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Psmb8
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 3426
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-10-04
Status: ACTIVE