Annotation (Toggle Detail/Summary View) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene-Chemical Interaction AnnotationsGene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of GIPR mRNA | CTD | PMID:16483693 | cadmium atom | increases expression | ISO | RGD:732777 | 6480464 | Cadmium results in increased expression of GIPR mRNA | CTD | PMID:21694771 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] affects the expression of GIPR mRNA | CTD | PMID:18636392 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] affects the expression of GIPR mRNA | CTD | PMID:18636392 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway Annotations| External Database Links | |
| KEGG Pathway | Neuroactive ligand-receptor interaction |
Disease Annotations
|
|
|
Gene-Chemical Interaction Annotations
|
|
Gene Ontology Annotations
|
|
|
|
Molecular Pathway Annotations| External Database Links | |
| KEGG Pathway | Neuroactive ligand-receptor interaction |
References - curated| 1. |
Boylan MO, etal., Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1287-95. Epub 2006 Jan 10. |
| 2. |
Buhren BA, etal., J Neurosci Res. 2009 Jun;87(8):1858-70. |
| 3. |
Cho GJ, etal., Curr Eye Res. 2002 Dec;25(6):381-8. |
| 4. |
GOA data from the GO Consortium |
| 5. |
Harada N, etal., Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E61-8. Epub 2007 Oct 30. |
| 6. |
Herbach N, etal., Am J Physiol Renal Physiol. 2009 Apr;296(4):F819-29. Epub 2009 Feb 11. |
| 7. |
Herbach N, etal., Regul Pept. 2005 Feb 15;125(1-3):103-17. |
| 8. |
Kato S, etal., Acta Neuropathol. 1992;83(3):277-82. |
| 9. |
Lewis JT, etal., Endocrinology. 2000 Oct;141(10):3710-6. |
| 10. |
Lynn FC, etal., Diabetes 2001 May;50(5):1004-11. |
| 11. |
Lynn FC, etal., FASEB J 2003 Jan;17(1):91-3. |
| 12. |
Miyawaki K, etal., Nat Med 2002 Jul;8(7):738-42. |
| 13. |
Miyawaki K, etal., Proc Natl Acad Sci U S A 1999 Dec 21;96(26):14843-7. |
| 14. |
NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 15. |
Nitz I, etal., Mol Nutr Food Res. 2007 Aug;51(8):1046-52. |
| 16. |
RGD automated data pipeline |
| 17. |
RGD automated import pipeline for gene-chemical interactions |
| 18. |
Rudovich N, etal., Regul Pept. 2007 Aug 16;142(3):138-45. Epub 2007 Feb 23. |
| 19. |
Shu L, etal., Hum Mol Genet. 2009 Jul 1;18(13):2388-99. Epub 2009 Apr 21. |
| 20. |
Tentative Sequence Data IDs. TIGR Gene Index, Rat Data |
| 21. |
Tseng CC and Zhang XY, Mol Cell Endocrinol. 1998 Apr 30;139(1-2):179-86. |
| 22. |
Tseng CC, etal., Am J Physiol. 1996 Apr;270(4 Pt 1):E661-6. |
| 23. |
Tseng CC, etal., J Clin Invest. 1996 Dec 1;98(11):2440-5. |
| 24. |
Usdin TB, etal., Endocrinology 1993 Dec;133(6):2861-70. |
| 25. |
Vogel CI, etal., BMC Med Genet. 2009 Mar 2;10:19. |
| 26. |
Zhou J, etal., Am J Physiol Endocrinol Metab. 2007 Aug;293(2):E538-47. Epub 2007 May 15. |
References - uncuratedRGD Disease Portals| Gipr has been annotated in the following RGD Disease Portals. |
|||||
 |
| ||||
 |
| ||||
 |
| ||||
Comparative Map Data| Gipr (Rattus norvegicus) |
|
|||||||||||||||||||||||||||||||||||
| GIPR (Homo sapiens) |
|
|||||||||||||||||||||||||||||||||||
| Gipr (Mus musculus) |
|
Position Markers| D1Wox30 |
|
|||||||||||||||||||||||||||||||||||||||||||||
| RH144450 |
|
QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_012714 | (Get FASTA) | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR06003873 | (Get FASTA) | Search GEO for Microarray Profiles |
| AAHX01004185 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH473979 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L19660 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_012714 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_036846 | ||||||||||||||||||||
| Peptide Label: | precursor | ||||||||||||||||||||
| Position: |
|
Protein Sequences| Protein RefSeqs | NP_036846 | (Get FASTA) |
| GenBank Protein | AAC37637 | (Get FASTA) |
| EDM08230 | (Get FASTA) | |
| EDM08231 | (Get FASTA) | |
| P43219 | (Get FASTA) |
Strain Sequence Variants
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000015860 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000021456 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000021456 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Entrez Gene | 25024 | ENTREZGENE |
| Germonline | ENSRNOG00000015860 | UniProtKB/Swiss-Prot |
| HomoloGene Group ID | 20081 | ENTREZGENE |
| InterPro | GPCR_2-like | UniProtKB/Swiss-Prot |
| GPCR_2_extracellular_dom | UniProtKB/Swiss-Prot | |
| GPCR_2_GIP_rcpt | UniProtKB/Swiss-Prot | |
| GPCR_2_secretin-like | UniProtKB/Swiss-Prot | |
| GPCR_2_secretin-like_CS | UniProtKB/Swiss-Prot | |
| IPI | IPI00198412 | UniProtKB/Swiss-Prot |
| KEGG Report | rno:25024 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Pfam | 7tm_2 | UniProtKB/Swiss-Prot |
| HRM | UniProtKB/Swiss-Prot | |
| PRINTS | GIPRECEPTOR | UniProtKB/Swiss-Prot |
| GPCRSECRETIN | UniProtKB/Swiss-Prot | |
| PROSITE | G_PROTEIN_RECEP_F2_1 | UniProtKB/Swiss-Prot |
| G_PROTEIN_RECEP_F2_2 | UniProtKB/Swiss-Prot | |
| G_PROTEIN_RECEP_F2_3 | UniProtKB/Swiss-Prot | |
| G_PROTEIN_RECEP_F2_4 | UniProtKB/Swiss-Prot | |
| SMART | HormR | UniProtKB/Swiss-Prot |
| TIGR | TC220766 | |
| UniGene | Rn.9676 | ENTREZGENE |
| UniProt | GIPR_RAT | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2004-09-10 | Gipr | gastric inhibitory polypeptide receptor | gastric inhibitory peptide receptor | Name updated | 10779 | APPROVED | |
| 2002-06-10 | Gipr | gastric inhibitory peptide receptor | Symbol and Name status set to approved | 1490 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_disease | may be associated with type 2 diabetes | 68929 |
| gene_disease | decreased mRNA and protein expression is detected in pancreatic islets of the Vancouver diabetic fatty Zucker rat | 68929 |
| gene_function | receptor for GIP (gastric inhibitory peptide) | 68929 |
| gene_process | potentiates glucose-induced insulin secretion from the pancreatic beta cells | 68929 |
| More on Gipr | |
|
Entrez Gene |
|
Ensembl Gene |
| Genome Browser |
|
NCBI Map Viewer |
|
Vista |
|
Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 2689 |
| Created: | 2000-05-25 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-16 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.