Gene: Ptprr (protein tyrosine phosphatase, receptor type, R)
Rattus norvegicus
Symbol:
Ptprr
Name:
protein tyrosine phosphatase, receptor type, R
Description:
ENCODES a protein that exhibits protein kinase binding (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN nervous system development; neuron differentiation; in utero embryonic development (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; FOUND IN cell surface (ortholog); cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
PC12-PTP1; Pcptp1; protein tyrosine phosphatase PCPTP1; protein-tyrosine phosphatase PCPTP1; R-PTP-R; receptor-type tyrosine-protein phosphatase R; tyrosine phosphatase CBPTP
Orthologs:
Homo sapiens : PTPRR
(protein tyrosine phosphatase, receptor type, R)
HGNC
Mus musculus : Ptprr
(protein tyrosine phosphatase, receptor type, R)
MGI
Latest Assembly:
RGSC Genome Assembly v3.4
NCBI Annotation Information:
Annotation category: partial on reference assembly
Position:
Map Chr Position Strand Source Rat Cytogenetic Map 7 q22 NCBI RGSC Genome Assembly v5.0 7 59,041,711 - 59,084,462 + NCBI RGSC Genome Assembly v5.0 7 59,207,155 - 59,335,376 + NCBI RGSC Genome Assembly v3.4 7 55,324,246 - 55,612,945 + NCBI Rat Celera Assembly 7 48,446,749 - 48,710,763 + NCBI Genome Assembly 3.1 7 55,344,975 - 55,633,672 + NCBI
Model
Gene Ontology Annotations
634336 Anxrr17 Anxiety related response QTL 17 3.66 Anxiety response 7 1786555 121975577 Rat 2298547 Neuinf5 Neuroinflammation QTL 5 2.7 Neuroinflammation 7 10973606 87034412 Rat 1643004 Pain2 Pain QTL 2 1 Pain 7 10973606 103612887 Rat 1578652 Bmd15 Bone mineral density QTL 15 5.2 Bone mineral density femoral neck trabecular vBMD 7 11379354 64612198 Rat 738033 Anxrr6 Anxiety related response QTL 6 4.1 Anxiety response open field inner locomotion 7 18504784 63504784 Rat 2317059 Aia15 Adjuvant induced arthritis QTL 15 2.46 Joint/bone inflammation adjuvant induced 7 21202126 66202126 Rat 1354639 Spl5 Serum phospholipid level QTL 5 3.9 Lipid level LDL phospholipid 7 21790655 56589443 Rat 1641885 Alcrsp9 Alcohol response QTL 9 Alcohol response blood ethanol concentration 7 27664404 72664404 Rat 1549840 Bss5 Bone structure and strength QTL 5 9.8 Bone structure and strength Femoral midshaft moment of inertia 7 28333735 73333735 Rat 1300127 Srn1 Serum renin concentration QTL 1 3.49 Renin concentration salt-loaded 7 28488298 89945095 Rat 70190 Mcs6 Mammary carcinoma susceptibility QTL 6 2.29 Mammary tumor susceptibility 7 29204226 68057251 Rat 1300138 Hrtrt9 Heart rate QTL 9 4.72 Heart rate salt-loaded 7 32004504 57326584 Rat 1300132 Bp182 Blood pressure QTL 182 3.87 Blood pressure salt-loaded time series calculation 7 32004504 89945095 Rat 631534 Lnnr1 Liver neoplastic nodule remodeling QTL 1 3.85 .001 Liver neoplastic nodule remodeling frequency 7 38076588 83076588 Rat 631513 Scl7 Serum cholesterol level QTL 7 4.1 Lipid level cholesterol, males 7 42112081 87112081 Rat 2303629 Vencon3 Ventilatory control QTL 3 7.25 Ventilatory control re-oxygenation after hypoxia 7 44462790 60576660 Rat 61357 Bp38 Blood pressure QTL 38 1.6 .052 Blood pressure 7 44698822 125481104 Rat 634326 Hc3 Hypercalciuria QTL 3 2.1 Renal function calcium excretion 7 47007003 92007003 Rat 1358361 Sradr5 Stress Responsive Adrenal Weight QTL 5 5.55 Hypothalamic-pituitary-adrenal axis adrenal gland weight 7 47145687 114883369 Rat 1300179 Kidm5 Kidney mass QTL 5 3.51 Kidney mass salt-loaded 7 47145687 124315164 Rat 1300149 Cm6 Cardiac mass QTL 6 4.09 Cardiac mass salt-loaded left ventricle 7 47145774 107950815 Rat 631504 Cm27 Cardiac mass QTL 27 3.45 Cardiac mass left ventricle 7 47865637 125399168 Rat 738030 Anxrr8 Anxiety related response QTL 8 4.1 Anxiety response open field inner locomotion 7 50941627 95941627 Rat 2293667 Bss42 Bone structure and strength QTL 42 7.25 .0001 Bone structure 7 52159077 97159077 Rat 2293678 Bss24 Bone structure and strength QTL 24 6.71 .0001 Bone structure 7 52159077 97159077 Rat 2293707 Bss32 Bone structure and strength QTL 32 7.64 .0001 Bone structure 7 52159077 97159077 Rat 2300178 Bmd54 Bone mineral density QTL 54 5.3 .0001 Bone mineral density 7 52159077 97159077 Rat