Gene: Acvr1 (activin A receptor type 1) Rattus norvegicus
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Symbol: Acvr1
Name: activin A receptor type 1
Description: ENCODES a protein that exhibits activin receptor activity, type I; signal transducer, downstream of receptor, with serine/threonine kinase activity; SMAD binding; INVOLVED IN cellular response to glucocorticoid stimulus; protein phosphorylation; regulation of skeletal muscle tissue development; PARTICIPATES IN activin signaling pathway; cytokine mediated signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; ASSOCIATED WITH Diabetic Nephropathies; Acute Lung Injury (ortholog); ADENOCARCINOMA OF STOMACH (ortholog); FOUND IN activin receptor complex; apical part of cell (ortholog); integral component of plasma membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: activin A receptor, type 1; activin A receptor, type I; activin receptor type I; activin receptor type-1; activin type I receptor; ACTR-I; ALK2-B; serine/threonine-protein kinase receptor R1; SKR1; TGF-B superfamily receptor type I; TSR-I
Orthologs:
Homo sapiens (human) : ACVR1 (activin A receptor type 1)  HGNC
Mus musculus (house mouse) : Acvr1 (activin A receptor, type 1)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Acvr1 (activin A receptor type 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ACVR1 (activin A receptor type 1)
Canis lupus familiaris (dog) : ACVR1 (activin A receptor type 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acvr1 (activin A receptor type 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0344,432,476 - 44,539,680 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0349,551,411 - 49,641,517 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4340,191,727 - 40,260,488 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1340,088,098 - 40,156,860 (-)NCBI
Celera341,046,965 - 41,113,654 (-)NCBI
Cytogenetic Map3q21NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
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RGD Object Information
RGD ID: 620200
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2017-08-08
Status: ACTIVE