Gene: Pde4d (phosphodiesterase 4D) Rattus norvegicus
Symbol: Pde4d
Name: phosphodiesterase 4D
Description: ENCODES a protein that exhibits 3',5'-cyclic-AMP phosphodiesterase activity; beta-2 adrenergic receptor binding; cAMP binding; INVOLVED IN adrenergic receptor signaling pathway; cAMP catabolic process; cellular protein complex assembly; PARTICIPATES IN protein kinase A (PKA) signaling pathway; adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; ASSOCIATED WITH basilar artery occlusion; Brain Injuries; carotid artery occlusion; FOUND IN centrosome; Golgi apparatus; myofibril; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3',5'-cyclic AMP phosphodiesterase; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; cAMP-specific phosphodiesterase PDE4D; cAMP-specific phosphodiesterase splice variant PDE4D8; DPDE3; PDE3/IVd; Phosphodiesterase 4D cAMP-specific (dunce; Phosphodiesterase 4D cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3); phosphodiesterase 4D, cAMP specific; Phosphodiesterase 4D, cAMP-specific (dunce; phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)
Homo sapiens (human) : PDE4D (phosphodiesterase 4D)  HGNC
Mus musculus (house mouse) : Pde4d (phosphodiesterase 4D, cAMP specific)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Pde4d (phosphodiesterase 4D)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE4D (phosphodiesterase 4D)
Canis lupus familiaris (dog) : PDE4D (phosphodiesterase 4D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde4d (phosphodiesterase 4D)
more info ...
Allele / Splice: Pde4dTn(sb-T2/Bart3)2.285Mcwi  
Genetic Models: F344-Pde4dTn(sb-T2/Bart3)2.285Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0240,219,999 - 41,468,551 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0260,035,104 - 60,521,358 (+)NCBIRnor5.0rn5Rnor5.0
Rnor_5.0259,292,847 - 59,860,049 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4240,196,097 - 41,311,012 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1241,035,303 - 41,231,381NCBI
Celera236,258,764 - 37,353,786 (+)NCBI
Cytogenetic Map2q14NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Pde4d
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 3281
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-09-05
Status: ACTIVE